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Research profile
Richard Lopata is an Associate Professor at the TU/e research group Cardiovascular Biomechanics (department of Biomedical Engineering) where he leads the PULS/e lab, Photoacoustics & Ultrasound Laboratory Eindhoven. The PULS/e lab facilitates research on technology development, such as ultrasound functional imaging, photoacoustics and image-based modeling; and more applied science, in particular ultrasound-based biomechanical modeling for improved clinical decision making.
In his research, Richard Lopata aims amongst others at the ultrasonic characterization of vulnerable arteries, such as aneurysms and plaques. A patient-specific biomechanical model of these arteries may help to better assess rupture risk, and ultrasound has the ability to provide highly detailed information on plaque geometry and distensibility. A second research line concerns the development and testing of 2-D and 3-D ultrasound imaging techniques for the assessment of cardiac function. The focus here is on acquisition, algorithms and methods that process the (raw) ultrasound data to produce measurements, needed in the clinic, and on methods to validate these measurements. These functional imaging techniques include motion/strain imaging, flow imaging and multi-perspective ultrasound imaging. Recent efforts are aimed at the assessment of cardiac function during exercise, together with USONO (spin-off company).
Photoacoustic imaging techniques, aimed at skin disease and plaque vulnerability assessment, are developed and validated in a preclinical setting.
Close collaborations with both clinical and technical partners were established over the years, paramount for a successful translation of these techniques from bench (lab) to bedside (clinic).
Academic background
Richard Lopata studied BioMedical Engineering at Eindhoven University of Technology (TU/e, The Netherlands) and received his MSc in 2004 on pharmacokinetic parameter estimation in dynamic contrast-enhanced MRI. From 2004-2009, Richard performed PhD research at the Clinical Physics Laboratory of Radboudumc (Nijmegen, The Netherlands), resulting in his PhD thesis on '2D and 3D Ultrasound Strain Imaging: Methods & In Vivo Applications'.
The following two years,he was a postdoctoral researcher at Maastricht University Medical Center (The Netherlands) and TU/e. In this period he was awarded a NWO-TTW VENI grant (2011).
In 2012, he became an assistant professor at TU/e. He works at the TU/e research group for Cardiovascular Biomechanics (department of Biomedical Engineering). Lopata founded the Photoacoustics and Ultrasound Laboratory Eindhoven, PULS/e. in 2014. In this period, Lopata was granted several EU-funded grants (FP7, H2020) and national grants.
In January 2017, he was appointed associate professor, receiving an ERC starting grant later that year. He has graduated over 35 MSc students and 1 PhD student, and is currently supervising 9 PhD students, two post-docs and 10 MSc students.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 3 Active
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PISANO/TKI/PPS/BMT
Lopata, R. G. P., Lopata, R. G. P. & van Aarle, D. A. C.
1/09/21 → 31/08/26
Project: Research direct
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TKI-HTSM/20.0295/PPS2006 MEDUSA
Lopata, R. G. P. & Gillissen, M.
1/01/21 → 5/02/26
Project: Research direct
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An aberration correction approach for single and dual aperture ultrasound imaging of the abdomen
van Hal, V. H. J., Muller, J-W., van Sambeek, M. R. H. M., Lopata, R. G. P. & Schwab, H. M., May 2023, In: Ultrasonics. 131, 11 p., 106936.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Downloads (Pure) -
A Radon diffraction theorem for plane wave ultrasound imaging
Schwab, H-M. & Lopata, R., 1 Feb 2023, In: Journal of the Acoustical Society of America. 153, 2, p. 1015-1026 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Downloads (Pure) -
Bandwidth Improvement in Ultrasound Image Reconstruction Using Deep Learning Techniques
Awasthi, N., van Anrooij, L., Jansen, G., Schwab, H. M., Pluim, J. P. W. & Lopata, R. G. P., Jan 2023, In: Healthcare (Switzerland). 11, 1, 19 p., 123.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Downloads (Pure) -
Coherent Bistatic 3-D Ultrasound Imaging using Two Sparse Matrix Arrays
de Hoop, H., Vermeulen, M. C. T., Schwab, H-M. & Lopata, R. G. P., 1 Mar 2023, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 70, 3, p. 182-196 15 p., 10003218.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile32 Downloads (Pure) -
Contactless Cardiovascular Assessment by Imaging Photoplethysmography: A Comparison with Wearable Monitoring
van Es, V. A. A., Lopata, R. G. P., Scilingo, E. P. & Nardelli, M., Feb 2023, In: Sensors. 23, 3, 18 p., 1505.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure)
Prizes
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Multi-perspective Ultrasound Strain Imaging & Elastography
Lopata, Richard G.P. (Recipient), 2017
Prize: ERC › Starting › Scientific
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NWO Veni Award : Monitoring an aneurysm with an ultrasonogram
Lopata, Richard G.P. (Recipient), 2011
Prize: NWO › Veni › Scientific
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The stiffening of arteries viewed from multiple angles
Lopata, Richard G.P. (Recipient), 2019
Prize: NWO › Vidi › Scientific
Courses
Press/Media
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Reports Summarize Sensor Research Research from University of Technology (Contactless Cardiovascular Assessment by Imaging Photoplethysmography: A Comparison with Wearable Monitoring)
Richard G.P. Lopata & Valerie van Es
28/02/23
1 item of Media coverage
Press/Media: Expert Comment
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Researchers at Eindhoven University of Technology Release New Study Findings on Abdominal Aortic Aneurysm (Local and global distensibility assessment of abdominal aortic aneurysms in vivo from probe tracked 2D ultrasound images)
Richard G.P. Lopata & Hans-Martin Schwab
25/01/23
1 item of Media coverage
Press/Media: Expert Comment
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Researchers' Work from Eindhoven University of Technology Focuses on Health and Medicine (Bandwidth Improvement in Ultrasound Image Reconstruction Using Deep Learning Techniques)
Richard G.P. Lopata, Josien P.W. Pluim, Hans-Martin Schwab, Laslo van Anrooij & Navchetan Awasthi
20/01/23
1 item of Media coverage
Press/Media: Expert Comment
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Eindhoven University of Technology: ERC Advanced Grants for Carlijn Bouten and Maurice Heemels
Carlijn V.C. Bouten & Richard G.P. Lopata
27/04/22
1 item of Media coverage
Press/Media: Expert Comment
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ERC Advanced Grants for Carlijn Bouten and Maurice Heemels
Carlijn V.C. Bouten & Richard G.P. Lopata
26/04/22
1 item of Media coverage
Press/Media: Expert Comment
Thesis
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Identifiability and optimal experiment design of the standard pharmacokinetic models for dynamic contrast-enhanced imaging of large tumour volumes
Author: Lopata, R. G. P., 30 Apr 2004Supervisor: van Riel, N. A. W. (Supervisor 1), Damen, A. A. H. (Supervisor 2) & Backes, W. H. (Supervisor 2)
Student thesis: Master