Research Output per year
Research Output 1998 2019
- 1 - 50 out of 77 results
- Publication Year, Title (descending)
2019
CALIMA: the semi-automated open-source calcium imaging analyzer
Radstake, F. D. W., Raaijmakers, E. A. L., Luttge, R., Zinger, S. & Frimat, J-P., 1 Oct 2019, In : Computer Methods and Programs in Biomedicine. 179, 10 p., 104991.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Calcium
Imaging techniques
Neurons
Cellular radio systems
Software
Characterizing the invasion of different breast cancer cell lines with distinct E-cadherin status in 3D using a microfluidic system
Eslami Amirabadi, H., Tuerlings, M., Hollestelle, A., Sahebali, S., Luttge, R., van Donkelaar, C. C. R., Martens, J. W. M. & den Toonder, J. M. J., 1 Dec 2019, In : Biomedical Microdevices. 21, 4, 11 p., 101.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Microfluidics
Cadherins
Cells
Breast Neoplasms
Cell Line
Exploiting nanogroove-induced cell culture anisotropy to advance in vitro brain models
Bastiaens, A., Frimat, J. P., van Nunen, T. & Luttge, R., 1 Nov 2019, In : Journal of Vacuum Science and Technology B: Nanotechnology and Microelectronics. 37, 6, 061802.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Brain models
Cell culture
brain
Anisotropy
anisotropy
Nanogroove-enhanced hydrogel scaffolds for 3D neuronal cell culture: an easy access brain-on-chip model
Bastiaens, A., Xie, S. & Luttge, R., 1 Oct 2019, In : Micromachines. 10, 10, 17 p., 638.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Scaffolds (biology)
Cell culture
Hydrogels
Brain
Brain models
The need for physiological micro-nanofluidic systems of the brain
Frimat, J-P. & Luttge, R., 7 May 2019, In : Frontiers in Bioengineering and Biotechnology. 7, MAY, 11 p., 100.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access
File
2018
Advancing a MEMS-Based 3D cell culture system for in vitro neuro-electrophysiological recordings
Bastiaens, A. J., Frimat, J. M. S., van Nunen, A. G. A., Schurink, B., Homburg, F. G. A. & Luttge, R., 13 Dec 2018, In : Frontiers in Mechanical Engineering. 4, p. 1-10 10 p., 21.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Micro-Electrical-Mechanical Systems
Cell Culture Techniques
Microelectrodes
Neurons
Fungi
Hybrid business models for ‘Organ-on-a-Chip’ technology: the best of both worlds
van de Burgwal, L. H. M., van Dorst, P., Viëtor, H., Luttge, R. & Claassen, E., 1 Jun 2018, In : PharmaNutrition. 6, 2, p. 55-63 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Technology
translation (genetics)
laboratory equipment
human physiology
Equipment and Supplies
2
Citations
(Scopus)
32
Downloads
(Pure)
Investigating the interplay of lateral and height dimensions influencing neuronal processes on nanogrooves
Bastiaens, A. J., Xie, S. & Luttge, R., 1 Nov 2018, In : Journal of Vacuum Science and Technology B: Nanotechnology and Microelectronics. 36, 6, 11 p., 06J801.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Polydimethylsiloxane
Lithography
Substrates
Cell culture
Atomic force microscopy
3
Citations
(Scopus)
48
Downloads
(Pure)
Nanoscale membrane actuator for in vitro mechano-stimuli responsive studies of neuronal cell networks on chip
Xie, S., Gardeniers, J. G. E. & Luttge, R., 9 May 2018, In : Journal of Micromechanics and Microengineering. 28, 8, 12 p., 085011.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Actuators
Membranes
Brain
Microfluidics
Brain models
3
Citations
(Scopus)
56
Downloads
(Pure)
Single cell trapping by capillary pumping using NOA81 replica moulded stencils
Moonen, E., Luttge, R. & Frimat, J. P., 5 Oct 2018, In : Microelectronic Engineering. 197, p. 1-7 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Syringes
Micromachining
replicas
Molding
Adhesives
3
Citations
(Scopus)
31
Downloads
(Pure)
Validation and optimization of an image-based screening method applied to the study of neuronal processes on nanogrooves
Bastiaens, A. J., Xie, S., Mustafa, D. A. M., Frimat, J-P., den Toonder, J. M. J. & Luttge, R., 6 Nov 2018, In : Frontiers in Cellular Neuroscience. 12, 14 p., 415.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Neurites
Software
Cues
Cultured Cells
Neurons
2017
A novel method to understand tumor cell invasion: integrating extracellular matrix mimicking layers in microfluidic chips by "selective curing"
Eslami Amirabadi, H., Sahebali, S., Frimat, J. M. S., Luttge, R. & den Toonder, J. M. J., 17 Oct 2017, In : Biomedical Microdevices. 19, 4, 11 p., 19:92.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
2
Citations
(Scopus)
2
Downloads
(Pure)
Fabrication and characterization of microsieve electrode array (μSEA) enabling cell positioning on 3D electrodes
Schurink, B., Tiggelaar, R. M., Gardeniers, J. G. E. & Luttge, R., 1 Jan 2017, In : Journal of Micromechanics and Microengineering. 27, 1, p. 1-16 015017.Research output: Contribution to journal › Article › Academic › peer-review
Sieves
Fabrication
Electrodes
Silicon
Boron
1
Citation
(Scopus)
1
Downloads
(Pure)
In Vitro and In Vivo evaluation of a hydrogel-based microneedle device for transdermal electro-modulated analgesia
Indermun, S., Choonara, Y. E., Kumar, P., du Toit, L. C., Modi, G., Luttge, R., Govender, M. & Pillay, V., 2017, In : European Journal of Pharmaceutical Sciences. 106, 4, p. 1111–1116 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Hydrogel
Analgesia
Chronic Pain
Equipment and Supplies
Pharmacokinetics
Passive pumping for the parallel trapping of single neurons onto a microsieve electrode array
Frimat, J. P., Schurink, B. & Luttge, R., 1 Nov 2017, In : Journal of Vacuum Science and Technology B: Nanotechnology and Microelectronics. 35, 6, 6 p., 06GA01.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
neurons
Neurons
pumping
trapping
chips
2016
1
Citation
(Scopus)
An actuator chip for in vitro mechano-stimuli responsive studies of primary cortical cell networks
Xie, S., Gardeniers, J. G. E. & Luttge, R., 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 495-496 2 p. M045bResearch output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Polydimethylsiloxane
Microfluidics
Pneumatics
Lithography
Rats
4
Citations
(Scopus)
67
Downloads
(Pure)
Displacement Talbot lithography nanopatterned microsieve array for directional neuronal network formation in brain-on-chip
Xie, S., Schurink, B., Berenschot, E. J. W., Tiggelaar, R. M., Gardeniers, J. G. E. & Luttge, R., 1 Nov 2016, In : Journal of Vacuum Science and Technology B: Nanotechnology and Microelectronics. 34, 6, p. 1-7 06KI02.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Microelectrodes
Lithography
brain
Brain
lithography
1
Citation
(Scopus)
2
Downloads
(Pure)
Drug delivery through microneedles
Luttge, R., 1 Jan 2016, Microsystems for Pharmatechnology : Manipulation of Fluids, Particles, Droplets, and Cells. Dietzel, A. (ed.). Dordrecht: Springer, p. 275-298 24 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Drug delivery
Technology
Pharmaceutical Preparations
Vaccines
Drug products
3
Citations
(Scopus)
Nano- and microfabrication for industrial and biomedical applications
Luttge, R., 15 Jun 2016, 2nd ed. Elsevier. 278 p. (Micro and nano technologies)Research output: Book/Report › Book › Academic
Microfabrication
Nanotechnology
Microsystems
Lithography
Nanolithography
2015
Advances in 3D neuronal cell culture
Frimat, J. M. S., Xie, S., Bastiaens, A. J., Schurink, B., Wolbers, F., den Toonder, J. M. J. & Luttge, R., 2015, In : Journal of Vacuum Science and Technology, B. 33, p. 1-6 06F902.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
120
Downloads
(Pure)
Cancer intravasation-on-a-chip : a LEGO house for tumors!
Eslami Amirabadi, H., Sahebali, S., Miggiels, A. L. W., Frimat, J. P., Luttge, R. & den Toonder, J., Nov 2015.Research output: Contribution to conference › Poster › Academic
Open Access
File
Neoplasms
Microfluidics
Extracellular Matrix
Ethics
Blood Vessels
16
Citations
(Scopus)
Controlled release of a model vaccine by nanoporous ceramic microneedle arrays
Boks, M. A., Unger, W. W. J., Engels, S., Ambrosini, M., Van Kooyk, Y. & Luttge, R., 14 Jul 2015, In : International Journal of Pharmaceutics. 491, 1-2, p. 375-383 9 p., 14977.Research output: Contribution to journal › Article › Academic › peer-review
Ceramics
Vaccines
T-Lymphocytes
Vaccination
Syringes
1
Citation
(Scopus)
2
Downloads
(Pure)
Ex vivo evaluation of a microneedle array device for transdermal application
Indermun, S., Choonara, Y. E., Kumar, P., Du Toit, L. C., Modi, G., Van Vuuren, S., Luttge, R. & Pillay, V., 30 Dec 2015, In : International Journal of Pharmaceutics. 496, 2, p. 351-359 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Equipment and Supplies
Skin
Hydrogel
Swine
Pharmaceutical Preparations
10
Citations
(Scopus)
Highly uniform sieving structure by corner lithography and silicon wet etching
Schurink, B., Berenschot, E. J. W., Tiggelaar, R. M. & Luttge, R., 16 Aug 2015, In : Microelectronic Engineering. 144, p. 12-18 7 p.Research output: Contribution to journal › Article › Academic › peer-review
sieves
Sieves
Wet etching
Silicon
Lithography
Insertion process of ceramic nanoporous microneedles by means of a novel mechanical applicator design
Hartmann, X. H. M., van der Linde, P., Homburg, F. G. A., van Breemen, L. C. A., de Jong, A. M. & Luttge, R., 18 Nov 2015, In : Pharmaceutics. 7, 4, p. 503-522 20 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Ceramics
Thumb
Adhesives
Skin
Artificial Skin
84
Downloads
(Pure)
Integration of electro-spun scaffolds inside microfluidic chips : towards 3D migration assays on a chip
Eslami Amirabadi, H., Sahebali, S., Miggiels, A. L. W., Frimat, J-P., Luttge, R. & den Toonder, J., Nov 2015.Research output: Contribution to conference › Poster › Academic
Open Access
File
Microfluidics
Scaffolds
Assays
Microfabrication
Controllability
Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays
van der Maaden, K., Luttge, R., Vos, P. J. W., Bouwstra, J., Kersten, G. & Ploemen, I. H. J., Aug 2015, In : Drug Delivery and Translational Research. 5, 4, p. 397-406Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
2014
An interfacially plasticized electro-responsive hydrogel for transdermal electro-activated and modulated (TEAM) drug delivery
Indermun, S., Choonara, Y. E., Kumar, P., Toit, Du, L. C., Modi, G., Luttge, R. & Pillay, V., 2014, In : International Journal of Pharmaceutics. 462, 1-2, p. 52-65 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Hydrogel
Hydrogels
Pharmaceutical Preparations
carbopol 940
Drug Delivery Systems
107
Downloads
(Pure)
Cancer intravasation-on-a-chip (CIChip) : towards tumor tissue engineering
Eslami Amirabadi, H., Frimat, J. M. S., Luttge, R. & Toonder, den, J. M. J., 2014.Research output: Contribution to conference › Poster › Academic
Open Access
File
Current advances in the fabrication of microneedles for transdermal delivery
Indermun, S., Luttge, R., Choonara, Y. E., Kumar, P., Toit, Du, L. C., Modi, G. & Pillay, V., 2014, In : Journal of Controlled Release. 185, p. 130-138Research output: Contribution to journal › Article › Academic › peer-review
Needles
Needlestick Injuries
Macromolecular Substances
Phobic Disorders
Drug Delivery Systems
Imprint lithography provides topographical nanocues to guide cell growth in primary cortical cell culture
Xie, S. & Luttge, R., 2014, In : Microelectronic Engineering. 124, p. 30-36 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Polyethyleneimine
Cell growth
Cell culture
Lithography
Brain
7
Citations
(Scopus)
Nanoscaffold's stiffness affects primary cortical cell network formation
Xie, S., Schurink, B., Wolbers, F., Luttge, R. & Hassink, G., 1 Nov 2014, In : Journal of Vacuum Science and Technology B: Nanotechnology and Microelectronics. 32, 6, 5 p., 06FD03.Research output: Contribution to journal › Article › Academic › peer-review
stiffness
Stiffness
Silicon
Polydimethylsiloxane
brain
6
Citations
(Scopus)
Patient-controlled analgesia: therapeutic interventions using transdermal electro-activated and electro-modulated drug delivery
Indermun, S., Choonara, Y. E., Kumar, P., Du Toit, L. C., Modi, G., Luttge, R. & Pillay, V., 2014, In : European Journal of Pharmaceutical Sciences. 103, 2, p. 353-366 14 p.Research output: Contribution to journal › Review article › Academic › peer-review
Patient-Controlled Analgesia
Chronic Pain
Iontophoresis
Pharmaceutical Preparations
Drug Delivery Systems
10
Downloads
(Pure)
Towards the development of spatially standardized 3D neuronal cultures
Frimat, J. M. S., Bastiaens, A. J., Xie, S., Luttge, R. & Toonder, den, J. M. J., 2014.Research output: Contribution to conference › Poster › Academic
2013
23
Downloads
(Pure)
Brain on a chip
Wolbers, F., Schurink, B., Xie, S., Toonder, den, J. M. J. & Luttge, R., 2013.Research output: Contribution to conference › Poster › Academic
317
Downloads
(Pure)
Cancer metastasis-on-a-chip
Eslami Amirabadi, H., Luttge, R. & Toonder, den, J. M. J., 2013.Research output: Contribution to conference › Poster › Academic
Open Access
File
Hydrogel/poly-dimethylsiloxane hybrid bioreactor facilitating 3D cell culturing
Schurink, B. & Luttge, R., 2013, In : Journal of Vacuum Science and Technology, B. 31, 6, 5 p., 06F903.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
cell culturing
bioreactors
Polydimethylsiloxane
Bioreactors
Hydrogels
The effect of nanometric surface texture on bone contact to titanium implants in rabbit tibia
Prodanov, L., Lamers, E., Domanski, M., Luttge, R., Jansen, J. A. & Walboomers, X. F., 2013, In : Biomaterials. 34, 12, p. 2920-2927 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Titanium
Tibia
Bone
Textures
Rabbits
2012
Applying ceramic nanoporous microneedle arrays as a transport interface in egg plants and an ex-vivo human skin model
Verhoeven, M., Bystrova, S. N., Winnubst, L., Qureshi, H., Gruijl, de, T. D., Scheper, R. J. & Luttge, R., 2012, In : Microelectronic Engineering. 98, p. 659-662 4 p.Research output: Contribution to journal › Article › Academic › peer-review
eggs
delivery
Skin
Porosity
ceramics
38
Citations
(Scopus)
63
Downloads
(Pure)
Dynamic cell adhesion and migration on nanoscale grooved substrates
Lamers, E., Riet, te, J., Domanski, M., Luttge, R., Figdor, C. G., Gardeniers, J. G. E., Walboomers, X. F. & Jansen, J. A., 2012, In : European Cells and Materials. 23, p. 182-194Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Cell adhesion
Cell Adhesion
Cell Movement
Adhesion
Substrates
Influence of partner diversity on collaborative public R&D project outcomes : a study of application and commercialization of nanotechnologies in the Netherlands
Raesfeld, A. V., Geurts, P., Jansen, M., Boshuizen, J. & Luttge, R., 2012, In : Technovation. 32, 3-4, p. 227-233 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Nanotechnology
Commercialization
The Netherlands
Technological diversity
Value chain
In vitro and in vivo evaluation of the inflammatory response to nanoscale grooved substrates
Lamers, E., Walboomers, X. F., Domanski, M., Prodanov, L., Melis, J., Luttge, R., Winnubst, A. J. A., Anderson, J. M., Gardeniers, J. G. E. & Jansen, J. A., 2012, In : Nanomedicine. 8, 3, p. 308-317Research output: Contribution to journal › Article › Academic › peer-review
Macrophages
Biocompatible Materials
Interleukin-1
Cytokines
Biomaterials
Production and characterization of miro- and nano-features in biomedical alumina and zirconia ceramics using a tape casting route
Domanski, M., Winnubst, A. J. A., Luttge, R., Lamers, E., Walboomers, X. F., Jansen, J. A. & Gardeniers, J. G. E., 2012, In : Journal of Materials Science: Materials in Medicine.Research output: Contribution to journal › Article › Academic › peer-review
Aluminum Oxide
Ceramics
Silicon
Zirconia
Tapes
Submicron-patterning of bulk titanium by nanoimprint lithography and reactive ion etching
Domanski, M., Luttge, R., Lamers, E., Walboomers, X. F., Winnubst, A. J. A., Jansen, J. A. & Gardeniers, J. G. E., 2012, In : Nanotechnology. 23, 6, 065306.Research output: Contribution to journal › Article › Academic › peer-review
Nanoimprint lithography
Reactive ion etching
Titanium
Silicon
Masks
2011
Cryo dualbeam focused ion beam-scanning electron microscopy to evaluate the interface between cells and nanopatterned scaffolds
Lamers, E., Walboomers, X. F., Domanski, M., McKerr, G., O'Hagan, B. M., Barnes, C. A., Peto, L., Luttge, R., Winnubst, A. J. A., Gardeniers, J. G. E. & Jansen, J. A., 2011, In : Tissue Engineering. Part C: Methods. 17, 1, p. 1-7Research output: Contribution to journal › Article › Academic › peer-review
Micromolding for ceramic microneedle arrays
Bystrova, S. N. & Luttge, R., 2011, In : Microelectronic Engineering. 88, 8, p. 1681-1684Research output: Contribution to journal › Article › Academic › peer-review
Silicones
ceramics
Fabrication
Silicone Elastomers
microhardness
Nanotechnology
Luttge, R., 2011, Microfabrication for Industrial Applications. Luttge, R. (ed.). Boston: William Andrew Publishing, p. 91-146 312 p. (Micro and Nano Technologies).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
nanotechnology
2010
Nanolithography for oxide nanoarrays and their application in medical devices
Luttge, R., 2010, Oxide-based Materials and Devices, 23 January 2010, San Francisco, California. Teherani, F. H., Look, D. C., Litton, C. W. & Rogers, D. J. (eds.). Bellingham: SPIE, p. 76031J- (Proceedings of SPIE; vol. 7603).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Nanolithography
Oxides
Metamaterials
Medical applications
Photonic crystals
1
Citation
(Scopus)
Novel approach to produce nanopatterned titanium implants by combining nanoimprint lithography and reactive ion etching
Domanski, M., Luttge, R., Lamers, E., Winnubst, A. J. A., Walboomers, X. F., Jansen, J. A. & Gardeniers, J. G. E., 2010, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2010), 3-7 October 2010, Groningen, The Netherlands. San Diego: Chemical and Biological Microsystems Society, Vol. 1. p. 518-520Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
grooves
lithography
titanium
etching
nanofabrication
The influence of nanoscale grooved substrates on osteoblast behavior and extracellular matrix deposition
Lamers, E., Walboomers, X. F., Domanski, M., Riet, te, J., van Delft, F. C. M. J. M., Luttge, R., Winnubst, A. J. A., Gardeniers, J. G. E. & Jansen, J. A., 2010, In : Biomaterials. 31, 12, p. 3307-3316 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Osteoblasts
Extracellular Matrix
Bone
Bone and Bones
Substrates