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Personal profile

Quote

“I push the limits of sensitivity and resolution, to make the invisible visible.”

Research profile

Peter Zijlstra is an associate professor of Molecular Plasmonics in the research group for Molecular Biosensing for Medical Diagnostics, a joint group of the TU/e departments of Applied Physics and Biomedical Engineering. He develops approaches for single-molecule sensing with the aim to study individual biomolecules in complex environments. In particular, his research focuses on single-molecule detection using plasmonic and fluorescent approaches. His research group combines concepts from single-molecule microscopy, plasmonics, super-resolution miicroscopy and modelling to develop novel sensing concepts and study biomolecular interactions. 

Visit the group website (www.molecular-plasmonics.nl) and the Marie Curie ITN SuperCol (www.supercol.eu) for more information.

Academic background

Peter Zijlstra studied Applied Physics at the University of Twente (Enschede, The Netherlands), where he obtained his MSc degree in 2005. In 2009, he received his PhD from Swinburne University of Technology (Melbourne, Australia), where he studied the photothermal properties of single plasmonic nanoparticles with applications in optical data storage. After a postdoctoral fellowship in the lab of Prof. Michel Orrit at Leiden University (The Netherlands) he moved to Eindhoven University of Technology (TU/e, The Netherlands). He is currently an associate professor in the research group Molecular Biosensing at the department of Applied Physics. He is a core member of the Institute for Complex Molecular Systems at TU/e, wherein groups from different disciplines (chemistry, physics, biomedical engineering, mathematics) collaborate on multidisciplinary research topics.

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Research Output

  • 776 Citations
  • 23 Article
  • 9 Poster
  • 8 Conference contribution
  • 2 Chapter

Dynamic single-molecule counting for the quantification and optimization of nanoparticle functionalization protocols

Horáček, M., Engels, D. J. & Zijlstra, P., 14 Feb 2020, In : Nanoscale. 12, 6, p. 4128-4136 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
  • 3 Downloads (Pure)

    Strong plasmon enhancement of the saturation photon count rate of single molecules

    Wang, Y., Horáček, M. & Zijlstra, P., 5 Mar 2020, In : Journal of Physical Chemistry Letters. 11, 5, p. 1962-1969 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • 3 Downloads (Pure)

    A robust and general approach to quantitatively conjugate enzymes to plasmonic nanoparticles

    Wang, Y., van Asdonk, K. & Zijlstra, P., 23 Sep 2019, In : Langmuir. 35, 41, p. 13356−13363 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • 16 Downloads (Pure)

    Effect of film thickness on the far- and near-field optical response of nanoparticle-on-film systems

    Armstrong, R. E., van Liempt, J. C. & Zijlstra, P., 24 Oct 2019, In : Journal of Physical Chemistry C. 123, 42, p. 25801-25808 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • 19 Downloads (Pure)

    All-optical imaging of gold nanoparticle geometry using super-resolution microscopy

    Taylor, A., Verhoef, R., Beuwer, M., Wang, Y. & Zijlstra, P., 1 Feb 2018, In : Journal of Physical Chemistry C. 122, 4, p. 2336-2342 7 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • 14 Citations (Scopus)
    57 Downloads (Pure)

    Prizes

  • Activities

    • 5 Contributed talk

    Plasmon-enhanced Single-molecule Enzymology

    Yuyang Wang (Speaker), P. Zijlstra (Member)
    23 Jan 2018

    Activity: Talk or presentation typesContributed talkScientific

    Single-molecule plasmonic sensing

    Peter Zijlstra (Speaker)
    28 Oct 2015

    Activity: Talk or presentation typesContributed talkScientific

    Single-particle and single-molecule plasmonic sensing

    Peter Zijlstra (Speaker)
    12 Oct 2015

    Activity: Talk or presentation typesContributed talkScientific

    Optical microscopy of single metal nanoparticles

    Peter Zijlstra (Speaker)
    20 Jul 2015

    Activity: Talk or presentation typesContributed talkScientific

    Optical microscopy of single metal nanoparticles

    Peter Zijlstra (Speaker)
    17 Jul 2015

    Activity: Talk or presentation typesContributed talkScientific

    Courses

    Applied natural sciences formal

    1/09/12 → …

    Course

    Electromagnetism

    1/09/12 → …

    Course

    Experimental physics 2

    1/09/12 → …

    Course

    Student theses

    (In,Ga)N heterostructures in self-assembled GaN nanowires grown on TiN by molecular beam epitaxy

    Author: Goertz, J. J., 2016

    Supervisor: Koenraad, P. M. (Supervisor 1), Geelhaar, L. (External person) (External coach), Bakkers, E. P. (Supervisor 2), Nijdam, S. (Supervisor 2) & Zijlstra, P. (Supervisor 2)

    Student thesis: Master

    File

    Binding kinetics in tethered particle biosensors

    Author: Almass, H., 2018

    Supervisor: Ellenbroek, W. G. (Supervisor 1) & Zijlstra, P. (Supervisor 2)

    Student thesis: Bachelor

    File

    Characterizing the optical properties of gold nanoparticles

    Author: Biemans, D., 2014

    Supervisor: Beuwer, M. (Supervisor 1) & Zijlstra, P. (Supervisor 2)

    Student thesis: Bachelor

    File

    Dark field microscopy of gold nanoparticles: rods versus bipyramids : a spectral analysis of nanoparticle size distribution

    Author: Peters, S. M., 2015

    Supervisor: Beuwer, M. (Supervisor 1) & Zijlstra, P. (Supervisor 2)

    Student thesis: Bachelor

    File

    Morphology of fluorescently labeled supramolecular fibers

    Author: Knopper, M., 2015

    Supervisor: Beuwer, M. (Supervisor 1) & Zijlstra, P. (Supervisor 2)

    Student thesis: Bachelor

    File