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Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Peter J. Cossar is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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14-3-3 Protein-Protein Interactions: From Mechanistic Understanding to Their Small-Molecule Stabilization
Somsen, B. A., Cossar, P. J., Arkin, M. R., Brunsveld, L. & Ottmann, C. (Corresponding author), 15 Jul 2024, In: ChemBioChem. 25, 14, 14 p., e202400214.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)50 Downloads (Pure) -
Discovery of 14-3-3 PPI Stabilizers by Extension of an Amidine-Substituted Thiophene Fragment
Wu, Q., Centorrino, F., Guillory, X., Wolter, M., Ottmann, C. (Corresponding author), Cossar, P. J. (Corresponding author) & Brunsveld, L. (Corresponding author), 2 Jan 2024, In: ChemBioChem. 25, 1, 9 p., e202300636.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)81 Downloads (Pure) -
A simple method for developing lysine targeted covalent protein reagents
Gabizon, R., Tivon, B., Reddi, R. N., van den Oetelaar, M. C. M., Amartely, H., Cossar, P. J., Ottmann, C. & London, N. (Corresponding author), Dec 2023, In: Nature Communications. 14, 1, 16 p., 7933.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)93 Downloads (Pure) -
Molecular basis and dual ligand regulation of tetrameric Estrogen Receptor α/14-3-3ζ protein complex
Somsen, B. A., Sijbesma, E., Leysen, S., Honzejkova, K., Visser, E. J., Cossar, P. J., Obšil, T., Brunsveld, L. (Corresponding author) & Ottmann, C. (Corresponding author), Jul 2023, In: Journal of Biological Chemistry. 299, 7, 16 p., 104855.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)68 Downloads (Pure) -
Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach
Somsen, B. A., Schellekens, R. J. C., Verhoef, C. J. A., Arkin, M. R., Ottmann, C., Cossar, P. J. (Corresponding author) & Brunsveld, L. (Corresponding author), 29 Mar 2023, In: Journal of the American Chemical Society. 145, 12, p. 6741-6752 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile18 Citations (Scopus)236 Downloads (Pure)
Courses
Press/Media
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Reports from University of Newcastle Add New Data to Findings in Pancreatic Cancer (Novel Piperazine-1,2,3-triazole Leads for the Potential Treatment of Pancreatic Cancer)
11/10/23
1 item of Media coverage
Press/Media: Expert Comment
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News Actions of Protein "Glues" Uncovered by Mass Spec Molecular "glues" are emerging as powerful tools that can stick proteins together in the body. Mass spectrometry has revealed new insights into the actions of these "glues".
Cossar, P. J. & Verhoef, K. J. A.
9/06/23
2 items of Media coverage
Press/Media: Expert Comment
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University of Birmingham: Mass Spectrometry Uncovers Actions of Protein 'Glues'
9/06/23
1 item of Media coverage
Press/Media: Expert Comment
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Mass spectrometry uncovers actions of protein ‘glues’
8/06/23
1 item of Media coverage
Press/Media: Expert Comment
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Mass spectrometry uncovers actions of protein 'glues'
8/06/23
1 item of Media coverage
Press/Media: Expert Comment