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Personal profile

Research profile

Peter Hilbers is full professor of BioModeling and BioInformatics at the department of Biomedical Engineering (research group Computational Biology). His main research interests are large scale computer simulations, computational modeling and applications in biomedical engineering, systems biology, molecular systems, catalysis, and polymer chemistry.

Academic background

Peter Hilbers studied Mathematics at the University of Groningen (The Netherlands) where he completed his PhD study on 'Mapping of algorithms on processor networks' in 1989. From 1989 until 1996, he worked at the Shell Research Laboratories in Amsterdam. In 1993, he was appointed part-time Professor of Large Scale Computing and Applications at Eindhoven University of Technology (TU/e, The Netherlands) and in 1996 he became a full Professor of BioModeling and BioInformatics. Peter Hilbers leads the research cluster BIOMedical Imaging & Modeling and also heads the Computational Biology research group at the TU/e department of Biomedical Engineering. Since 2005, he is involved in the research and educational programs of the Sino-Dutch Biomedical & Information Engineering School of Northeastern University, Shenyang, China. In October 2007, he became the dean of the TU/e department of Biomedical Engineering.

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Research Output 1987 2019

Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples

Félix Garza, Z. C., Lenz, M., Liebmann, J., Ertaylan, G., Born, M., Arts, I. C. W., Hilbers, P. A. J. & Van Riel, N. A. W., 17 Aug 2019, In : BMC Medical Genomics. 12, 1, 14 p., 121

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Biopsy
Skin
Atopic Dermatitis
Psoriasis
Skin Diseases

Computational modelling of bile acid and lipid metabolism

Sips, F. L. P., 3 Jul 2019, Eindhoven: Technische Universiteit Eindhoven. 226 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Bile Acids and Salts
Lipid Metabolism

Computational modelling of energy balance in individuals with Metabolic Syndrome

Rozendaal, Y., Wang, Y., Hilbers, P. & van Riel, N., 26 Feb 2019, In : BMC Systems Biology. 13, 24, 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Computational Modeling
Energy Balance
Energy balance
Energy Metabolism
Energy

Counterion-dependent mechanisms of DNA origami nanostructure stabilization revealed by atomistic molecular simulation

Roodhuizen, J., Hendrikx, P. J. T. M., Hilbers, P. A. J., de Greef, T. & Markvoort, B., 10 Sep 2019, In : ACS Nano. 13, p. 10798-10809

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
helices
Nanostructures
DNA
deoxyribonucleic acid
Stabilization

Dynamics in human muscle bioenergetics: in silico and in vivo studies of metabolism during exercise

Hendriks, A., Nabben, M. W., Schmitz, J. P. J., Hilbers, P. A. J., Prompers, J. J. & van Riel, N. A. W., 2019, (In preparation) Eindhoven: Technische Universiteit Eindhoven

Research output: Working paperAcademic

Courses

Molecular modeling

1/09/15 → …

Course

Programming and genomics

1/09/15 → …

Course

Project Computational biology

1/09/14 → …

Course

Systems medicine

1/09/14 → …

Course

Student theses

File

ABCB1 variants in association with clopidogrel response

Author: de Kock, R., 29 Sep 2016

Supervisor: Brunsveld, L. (Supervisor 1), Hilbers, P. (Supervisor 2), Scharnhorst, V. (Supervisor 2) & Deiman, B. (External person) (External coach)

Student thesis: Master

Accuracy assessment of inter-fraction dose accumulation using non-rigid deformation models

Author: Fekkes, S., 31 Aug 2008

Supervisor: van Elmpt, W. (Supervisor 1) & Hilbers, P. (Supervisor 2)

Student thesis: Master

A computational biology framework: a data analysis tool to support biomedical engineers in their research

Author: Beishuizen, T., 29 Nov 2018

Supervisor: Bosnacki, D. (Supervisor 1), Cheplygina, V. (Supervisor 2), Hilbers, P. (Supervisor 2), Fletcher, G. (Supervisor 2) & Vanschoren, J. (Supervisor 2)

Student thesis: Master

A computational model for the drug treatment effects for the EGF pathway

Author: van Tienhoven, S., 31 Jan 2013

Supervisor: van Riel, N. (Supervisor 1) & Hilbers, P. (Supervisor 2)

Student thesis: Master