• 322 Citations
20102019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2019

In vivo and in vitro approaches reveal novel insight into the ability of epicardium-derived cells to create their own extracellular environment

Bax, N. A. M., Duim, S. N., Kruithof, B. P. T., Smits, A. M., Bouten, C. V. C. & Goumans, M. J., 19 Jun 2019, In : Frontiers in Cardiovascular Medicine. 6, 14 p., 81.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
17 Downloads (Pure)
2017

Cardiac progenitor cells and the interplay with their microenvironment

Mauretti, A., Spaans, S., Bax, N. A. M., Sahlgren, C. & Bouten, C. V. C., 2017, In : Stem Cells International. 2017, 20 p., 7471582.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
14 Citations (Scopus)
84 Downloads (Pure)

Glycosylated cell surface markers for the isolation of human cardiac progenitors

Moerkamp, A. T., Leung, H. W., Bax, N. A. M., Holst, S., Lodder, K., Berends, T., Dingenouts, C. K. E., Choo, A., Smits, A. M. & Goumans, M. J., 1 Nov 2017, In : Stem Cells and Development. 26, 21, p. 1552-1565 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactions

Mollet, B. B., Spaans, S., Goodarzy Fard, P., Bax, N. A. M., Bouten, C. V. C. & Dankers, P. Y. W., 1 Sep 2017, In : Macromolecular Bioscience. 17, 9, 8 p., 1700053.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
65 Downloads (Pure)

Mimicking cardiac fibrosis in a dish: fibroblast density rather than collagen density weakens cardiomyocyte function

van Spreeuwel, A. C. C., Bax, N. A. M., van Nierop, B. J., Aartsma-Rus, A., Goumans, M. J. T. H. & Bouten, C. V. C., 1 Apr 2017, In : Journal of Cardiovascular Translational Research. 10, 2, p. 116-127 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
12 Citations (Scopus)
132 Downloads (Pure)

Spheroid three-dimensional culture enhances Notch signaling in cardiac progenitor cells

Mauretti, A., Rossi, F., Bax, N. A. M., Miano, C., Miraldi, F., Goumans, M. J., Messina, E., Giacomello, A., Bouten, C. V. C. & Sahlgren, C., 1 Sep 2017, In : MRS Communications. 7, 3, p. 496-501 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
7 Downloads (Pure)

Supramolecular surface functionalization via catechols for the improvement of cell-material interactions

Spaans, S., Fransen, P. P. K. H., Ippel, B. D., de Bont, D. F. A., Keizer, H. M., Bax, N. A. M., Bouten, C. V. C. & Dankers, P. Y. W., 7 Sep 2017, In : Biomaterials Science. 5, 8, p. 1541-1548 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
76 Downloads (Pure)
2016

Cardiac stem cell mechanosome and mechanosensitivity develop with differentiation

Mauretti, A., Bax, N. A. M., van Marion, M. H., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., 28 Jun 2016.

Research output: Contribution to conferencePoster

Open Access
File
28 Downloads (Pure)

Cardiac stem cell mechanosome and mechanosensitivity develop with differentiation

Mauretti, A., Bax, N. A. M., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., 22 Mar 2016.

Research output: Contribution to conferencePoster

Open Access
File
82 Downloads (Pure)

Cardiomyocyte progenitor cell mechanoresponse unrevealed: strain avoidance and mechanosome development.

Mauretti, A., Bax, N. A. M., van Marion, M. H., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., 12 Sep 2016, In : Integrative Biology. 8, 9, p. 991-1001 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
16 Downloads (Pure)

Mechanosensitivity of cardiomyocyte progenitor cells: the strain response in 2D and 3D environments

Bax, N. A. M., Mauretti, A., Van Marion, M. H., Van Turnhout, M. C., Van der Schaft, D. W. J., Sahlgren, C. M., Goumans, M. J. T. H. & Bouten, C. V. C., 1 Jul 2016, In : Cardiovascular Research. 111, suppl 1, p. S94-S94 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
File
37 Downloads (Pure)

Mechanosensitivity of CMPCs :strain response in 2D and 3D environments

Bax, N. A. M., Mauretti, A., van Marion, M. H., van Turnhout, M. C., van der Schaft, D. W. J., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., Sep 2016, International Society for Applied Cardiovascular Biology : ISACB, 7-10 September, Banff, Canada.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

8 Downloads (Pure)
2015

Assessment of myocardial fibrosis in mice using a T2*-weighted 3D radial magnetic resonance imaging sequence

van Nierop, B. J., Bax, N. A. M., Nelissen, J., Arslan, F., Motaal, A. G., de Graaf, L., Zwanenburg, J. J. M., Luijten, P. R., Nicolaij, K. & Strijkers, G. J., 26 Jun 2015, In : PLoS ONE. 10, 6, p. 1-15 15 p., e0129899.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
11 Citations (Scopus)
81 Downloads (Pure)

Behavior of CMPCs in unidirectional constrained and stress-free 3D hydrogels

Marion, van, M. H., Bax, N. A. M., van Turnhout, M. C., Mauretti, A., van der Schaft, D. W. J., Goumans, M. J. T. H. & Bouten, C. V. C., Oct 2015, In : Journal of Molecular and Cellular Cardiology. 87, p. 79-91

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
12 Downloads (Pure)

Behavior of CMPCs in unidirectional constrained and stress-free 3D hydrogels

van Marion, M. H., Bax, N. A., van Turnhout, M. C., van der Schaft, D. W., Goumans, M. J. T. H. & Bouten, C. V., 1 Sep 2015, In : Tissue engineering. Part A. 21, p. S341

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
94 Downloads (Pure)

Engineered cardiac microtissue model reveals no detrimental effect of fibrosis on beating frequency

van Spreeuwel, A. C., Bax, N. A., Chen, C. S. & Bouten, C. V. C., 1 Sep 2015, p. S223.

Research output: Contribution to conferenceAbstract

Open Access
File
48 Downloads (Pure)

Fibrosis has no detrimental effect on beating frequency in native-based cardiac microtissue models

Bax, N. A. M., van Spreeuwel, A. C. C., Chen, C. S. & Bouten, C. V. C., 2015.

Research output: Contribution to conferencePoster

The epicardium as modulator of the cardiac autonomic response during early development

Kelder, T. P., Duim, S. N., Vicente-Steijn, R., Végh, A. M. D., Kruithof, B. P. T., Smits, A. M., van Bavel, T. C., Bax, N., Schalij, M. J., Gittenberger-de Groot, A. C., DeRuiter, M. C., Goumans, M. J. T. H. & Jongbloed, M. R. M., 1 Dec 2015, In : Journal of Molecular and Cellular Cardiology. 89, p. 251-259 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
174 Downloads (Pure)
2014

Cardiac extracellular matrix analysis to engineer in vitro cardiac tissue models

Spreeuwel, van, A. C. C., Bax, N. A. M. & Bouten, C. V. C., 2014.

Research output: Contribution to conferencePoster

2 Downloads (Pure)

Material-based engineering strategies for cardiac regeneration

Marion, van, M. H., Bax, N. A. M., Spreeuwel, van, A. C. C., Schaft, van der, D. W. J. & Bouten, C. V. C., 2014, In : Current Pharmaceutical Design. 20, 12, p. 2057-2068

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Myocardial perfusion MRI shows impaired perfusion of the mouse hypertrophic left ventricle

Nierop, van, B. J., Coolen, B. F., Bax, N. A. M., Dijk, W. J. R., Deel, van, E. D., Duncker, D. J., Nicolay, K. & Strijkers, G. J., 2014, In : The International Journal of Cardiovascular Imaging. 30, 3, p. 619-628 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)
1 Downloads (Pure)

The influence of matrix (an)isotropy on cardiomyocyte contraction in engineered cardiac microtissues

Spreeuwel, van, A. C. C., Bax, N. A. M., Bastiaens, A. J., Foolen, J., Loerakker, S., Borochin, M. A., Schaft, van der, D. W. J., Chen, C. S., Baaijens, F. P. T. & Bouten, C. V. C., 2014, In : Integrative Biology. 6, 4, p. 422-429 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
26 Citations (Scopus)
110 Downloads (Pure)

The relevance of extracellular matrix structure and composition in engineering the diseased cardiac microenvironment

Spreeuwel, van, A. C. C., Bax, N. A. M. & Bouten, C. V. C., 2014, In : OA Tissue Engineering. 2, 1, p. 1-6

Research output: Contribution to journalArticleAcademicpeer-review

6 Downloads (Pure)
2013

Cardiac matrix analysis to mimic healhty and diseased matrix organization in vitro

Bax, N. A. M., Spreeuwel, van, A. C. C., Nierop, van, B. J., Chen, C. S. & Bouten, C. V. C., 2013.

Research output: Contribution to conferencePoster

5 Downloads (Pure)

Developing engineered cardiac tissue models from HL-1 cardiomyocytes and mouse embryonic fibroblasts

Acosta-Torres, Z., Bax, N. A. M., van Spreeuwel, A. C. C. & Bouten, C. V. C., 2013, Proceedings - 29th Southern Biomedical Engineering Conference, SBEC 2013. p. 39-40 2 p. 6525665

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Engineered microtissues for real-time characterization of cardiomyocyte function

van Spreeuwel, A. C. C., Bax, N. A. M., Foolen, J., Borochin, M. A., van der Schaft, D. W. J., Chen, C. S. & Bouten, C. V. C., 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. Vol. 1 A. 2 p. SBC2013-14248, pp. V01AT17A005

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Increased cardiac myocyte PDE5 levels in human and murine pressure overload hypertrophy cntribute to adverse LV remodeling

Vandenwijngaert, S., Pokreisz, P., Hermans, H., Gillijns, H., Pellens, M., Bax, N. A. M., Coppiello, G., Oosterlinck, W., Balogh, A., Papp, Z., Bouten, C. V. C., Bartunek, J., Hooge, d', J., Luttun, A., Verbeken, E., Herregods, M. C., Herijgers, P., Bloch, K. D. & Janssens, S., 2013, In : PLoS ONE. 8, 3, p. e58841-1/8

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
15 Citations (Scopus)
47 Downloads (Pure)

Influence of anisotropy on cardiomyocyte contraction in engineered microtissues

Spreeuwel, van, A. C. C., Bax, N. A. M., Bastiaens, A. J., Foolen, J., Loerakker, S., Borochin, M. A., Schaft, van der, D. W. J., Chen, C. S., Baaijens, F. P. T. & Bouten, C. V. C., 2013.

Research output: Contribution to conferencePoster

5 Downloads (Pure)
2012

3D microtissue platform for healthy and diseased human myocardium

Spreeuwel, van, A. C. C., Bax, N. A. M., Foolen, J., Borochin, M. A., Chen, C. S., Schaft, van der, D. W. J. & Bouten, C. V. C., 2012.

Research output: Contribution to conferencePoster

8 Downloads (Pure)

Dissecting healthy and diseased hearts

Bax, N. A. M., Spreeuwel, van, A. C. C., Schaft, van der, D. W. J. & Bouten, C. V. C., 2012.

Research output: Contribution to conferencePoster

5 Downloads (Pure)

Matrix production and proteolitic activity of cardiomyocyte progenitor cells during in vitro differentiation

Bax, N. A. M., Marion, van, M. H., Shah, B., Goumans, M. J. T. H., Bouten, C. V. C. & Schaft, van der, D. W. J., 2012, In : Cardiovascular Research. 93, S1, p. S56-S56

Research output: Contribution to journalMeeting AbstractAcademic

27 Citations (Scopus)
3 Downloads (Pure)
2011
179 Downloads (Pure)

Engineered cardiac model systems for dilated cardiomyopathy

Spreeuwel, van, A. C. C., Bax, N. A. M., Schaft, van der, D. W. J. & Bouten, C. V. C., 2011.

Research output: Contribution to conferencePoster

Open Access
File
51 Downloads (Pure)

Epithelial-to-mesenchymal transformation alters electrical conductivity of human epicardial cells

Bax, N. A. M., Pijnappels, D. A., van Oorschot, A. A. M., Winter, E. M., de Vries, A. A. F., van Tuyn, J., Braun, J., Maas, S., Schalij, M. J., Atsma, D. E., Goumans, M. J. T. H. & Gittenberger-de Groot, A. C., Dec 2011, In : Journal of Cellular and Molecular Medicine. 15, 12, p. 2675-2683

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
19 Citations (Scopus)
54 Downloads (Pure)

In vitro epithelial-to-mesenchymal transformation in human adult epicardial cells is regulated by TGFβ-signaling and WT1

Bax, N., Van Oorschot, A. A. M., Maas, S., Braun, J., Van Tuyn, J., De Vries, A. A. F., Gittenberger-De Groot, A. C. & Goumans, M. J. T. H., Sep 2011, In : Basic Research in Cardiology. 106, 5, p. 829-847 19 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
39 Citations (Scopus)
87 Downloads (Pure)
2010

Cardiac malformations in Pdgfrα mutant embryos are associated with increased expression of WT1 and Nkx2.5 in the second heart field

Bax, N. A. M., Bleyl, S. B., Gallini, R., Wisse, L. J., Hunter, J., Van Oorschot, A. A. M., Mahtab, E. A. F. E., Lie-Venema, H., Goumans, M. J. T. H., Betsholtz, C. & Gittenberger-de Groot, A. C., Aug 2010, In : Developmental Dynamics. 239, 8, p. 2307-2317 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)
1 Downloads (Pure)

Electrical activation of sinus venosus myocardium and expression patterns of RhoA and Isl-1 in the chick embryo

Vicente-Steijn, R., Kolditz, D. P., Mahtab, E. A. F., Askar, S. F., Bax, N. A. M., van der Graaf, L. M., Wisse, L. J., Pijnappels, D. A., Schalij, M. J., Poelmann, R. E., Gittenberger-de Groot, A. C. & Jongbloed, M. R. M., 2 Nov 2010, In : Journal of Cardiovascular Electrophysiology. p. 1284-1292

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Epicardium-derived cells enhance proliferation, cellular maturation and alignment of cardiomyocytes

Weeke-Klimp, A., Bax, N., Bellu, A. R., Winter, E. M., Vrolijk, J., Plantinga, J., Maas, S., Brinker, M., Mahtab, E. A. F. E., Gittenberger-de Groot, A. C., Luyn, van, M. J. A., Harmsen, M. C. & Lie-Venema, H., Oct 2010, In : Journal of Molecular and Cellular Cardiology. 49, 4, p. 606-616 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

44 Citations (Scopus)
1 Downloads (Pure)