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Research Output 2000 2019

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Article
2019

A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data

O'Donovan, S. D., Lenz, M., Vink, R. G., Roumans, N. J. T., de Kok, T. M. C. M., Mariman, E. C. M., Peeters, R. L. M., van Riel, N. A. W., van Baak, M. A. & Arts, I. C. W., 3 Oct 2019, In : PLoS Computational Biology. 15, 10, 23 p., e1007400

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lipid Metabolism
Radioactive tracers
isotope labeling
Isotopes
lipid metabolism

Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples

Félix Garza, Z. C., Lenz, M., Liebmann, J., Ertaylan, G., Born, M., Arts, I. C. W., Hilbers, P. A. J. & Van Riel, N. A. W., 17 Aug 2019, In : BMC Medical Genomics. 12, 1, 14 p., 121

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Biopsy
Skin
Atopic Dermatitis
Psoriasis
Skin Diseases

Computational modelling of energy balance in individuals with Metabolic Syndrome

Rozendaal, Y., Wang, Y., Hilbers, P. & van Riel, N., 26 Feb 2019, In : BMC Systems Biology. 13, 24, 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Computational Modeling
Energy Balance
Energy balance
Energy Metabolism
Energy

Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator

O’Donovan, S. D., Lenz, M., Goossens, G. H., van der Kallen, C. J. H., Eussen, S. J. M. P., Stehouwer, C. D. A., van Greevenbroek, M. M., Schram, M. T., Sep, S. J., Peeters, R. L. M., Blaak, E. E., van Riel, N. A. W., de Kok, T. M. C. M. & Arts, I. C. W., 28 Jun 2019, In : Scientific Reports. 9, 1, 10 p., 9388

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Glucose Tolerance Test
Insulin Resistance
Muscles
Appointments and Schedules
Glucose Clamp Technique
2018
13 Citations (Scopus)

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects

Bouter, K., Bakker, G. J., Levin, E., Hartstra, A. V., Kootte, R. S., Udayappan, S. D., Katiraei, S., Bahler, L., Gilijamse, P. W., Tremaroli, V., Stahlman, M., Holleman, F., van Riel, N. A. W., Verberne, H. J., Romijn, J. A., Dallinga-Thie, G. M., Serlie, M. J., Ackermans, M. T., Kemper, E. M., Willems van Dijk, K. & 3 othersBackhed, F., Groen, A. K. & Nieuwdorp, M., 25 May 2018, In : Clinical and Translational Gastroenterology. 9, 5, 155

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Butyrates
Volatile Fatty Acids
Brown Adipose Tissue
Glucose
Butyric Acid
1 Citation (Scopus)

Domain intelligible models

Imangaliyev, S., Prodan, A., Nieuwdorp, M., Groen, A. K., van Riel, N. A. W. & Levin, E., 1 Oct 2018, In : Methods : a companion to methods in enzymology. 149, p. 69-73

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Metagenome
Biological Phenomena
Microorganisms
Cost functions
Insulin Resistance
2 Citations (Scopus)

In silico analysis identifies intestinal transit as a key determinant of systemic bile acid metabolism

Sips, F. L. P., Eggink, H. M., Hilbers, P. A. J., Soeters, M. R., Groen, A. K. & van Riel, N. A. W., 8 Jun 2018, In : Frontiers in Physiology. 9, 631

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Bile Acids and Salts
Computer Simulation
Bariatric Surgery
Lipid Metabolism
Type 2 Diabetes Mellitus
4 Citations (Scopus)

In vivo and in silico dynamics of the development of Metabolic Syndrome

Rozendaal, Y. J. W., Wang, Y., Paalvast, Y., Tambyrajah, L. L., Li, Z., Willems van Dijk, K., Rensen, P. C. N., Kuivenhoven, J. A., Groen, A. K., Hilbers, P. A. J. & van Riel, N. A. W., 1 Jun 2018, In : PLoS Computational Biology. 14, 6, e1006145

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
metabolic syndrome
Cholesterol
Computer Simulation
Lipids
Glucose
6 Citations (Scopus)

Model-based analysis of postprandial glycemic response dynamics for different types of food

Rozendaal, Y. J., Maas, A. H., van Pul, C., Cottaar, E. J. E., Haak, H. R., Hilbers, P. A. J. & van Riel, N. A., Jun 2018, In : Clinical Nutrition Experimental. 19, p. 32-45

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Insulin
Glucose
Food
Meals
Glycemic Index
4 Citations (Scopus)

Physical activity and nutrition influences in ageing (PANINI): consortium mission statement

Whittaker, A. C., Delledonne, M., Finni, T., Garagnani, P., Greig, C., Kallen, V., Kokko, K., Lord, J., Maier, A. B., Meskers, C. G. M., Santos, N. C., Sipila, S., Thompson, J. L. & van Riel, N. A. W., Jun 2018, In : Aging Clinical and Experimental Research. 30, 6, p. 685-692

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)

Visible light therapy: molecular mechanisms and therapeutic opportunities

Felix Garza, Z. C., Born, M., Hilbers, P. A. J., van Riel, N. A. W. & Liebmann, J., 2018, In : Current Medicinal Chemistry. 25, 40, p. 5564-5577

Research output: Contribution to journalArticleAcademicpeer-review

Phototherapy
Light
Skin
Therapeutics
Flavins
2017

A dynamic model for prediction of psoriasis management by blue light irradiation

Felix Garza, Z. C., Liebmann, J., Born, M., Hilbers, P. A. J. & van Riel, N. A. W., 26 Jan 2017, In : Frontiers in Physiology. 8, p. 1-17 28

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)

An in vivo magnetic resonance spectroscopy study of the effects of caloric and non-caloric sweeteners on liver lipid metabolism in rats

Janssens, S., Ciapaite, J., Wolters, J. C., van Riel, N. A., Nicolay, K. & Prompers, J. J., 10 May 2017, In : Nutrients. 9, 5, 19 p., 476

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Sweetening Agents
sweeteners
Lipid Metabolism
lipid metabolism
spectroscopy
3 Citations (Scopus)

Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in patients with mitochondrial myopathy

Nabben, M., Schmitz, J. P. J., Ciapaite, J., le Clercq, C. M. P., van Riel, N. A., Haak, H. R., Nicolay, K., de Coo, I. F. M., Smeets, H., Praet, S. F., van Loon, L. J. & Prompers, J. J., 1 May 2017, In : American Journal of Physiology : Regulatory Integrative and Comparative Physiology. 312, 5, p. R689-R701 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mitochondrial Myopathies
Nitrates
Exercise
Oxygen
Costs and Cost Analysis
1 Citation (Scopus)

Identifying user preferences for a digital educational solution for young seniors with diabetes

van der Molen, P., Maas, A. H., Chen, W., van Pul, C., Cottaar, E. J. E., van Riel, N. A. W., Hilbers, P. A. J. & Haak, H. R., 1 Aug 2017, In : Diabetes Spectrum. 30, 3, p. 182-187 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Education
Interviews
Equipment and Supplies
Video Games
Research
10 Citations (Scopus)

Methodologies for quantitative systems pharmacology (QSP) models: Design and Estimation

Ribba, B., Grimm, H., Agoram, B., Davies, M. R., Gadkar, K., Niederer, S., van Riel, N., Timmis, J. & van der Graaf, P., 1 Aug 2017, In : CPT: Pharmacometrics & Systems Pharmacology. 6, 8, p. 496-498 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pharmacology
Methodology
Research
Medicine
Granularity
2016
22 Citations (Scopus)

A genome-scale metabolic network reconstruction of tomato (Solanum lycopersicum L.) and its application to photorespiratory metabolism

Yuan, H., Cheung, C. Y. M., Poolman, M. G., Hilbers, P. A. J. & van Riel, N. A. W., 1 Jan 2016, In : Plant Journal. 85, 2, p. 289-304 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
11 Citations (Scopus)

Altered energetics of exercise explain risk of rhabdomyolysis in very long-chain acyl-coa dehydrogenase deficiency

Diekman, E. F., Visser, G., Schmitz, J. P. J., Nievelstein, R. A. J., De Sain-van Der Velden, M., Wardrop, M., Van Der Pol, W. L., Houten, S. M., van Riel, N. A. W., Takken, T. & Jeneson, J. A. L., 16 Feb 2016, In : PLoS ONE. 11, 2, 18 p., e0147818

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Long-Chain Acyl-CoA Dehydrogenase
acyl-CoA dehydrogenase
rhabdomyolysis
Rhabdomyolysis
Oxidoreductases
3 Citations (Scopus)

Concept development of the Eindhoven Diabetes Education Simulator project

Maas, A. H., van der Molen, P., van de Vijver, R., Chen, W., van Pul, C., Cottaar, E. J. E., van Riel, N. A. W., Hilbers, P. A. J. & Haak, H., 30 Mar 2016, In : Games for Health Journal. 5, 2, p. 120-127 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Medical problems
chronic illness
Simulators
Education
education
10 Citations (Scopus)

Flux balance analysis of plant metabolism: the effect of biomass composition and model structure on model predictions

Yuan, H., Cheung, C. Y. M., Hilbers, P. A. J. & van Riel, N. A. W., 26 Apr 2016, In : Frontiers in Plant Science. 7, 13 p., 537

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)

Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes

Nyman, E., Rozendaal, Y. J. W., Helmlinger, G., Hamrén, B., Kjellsson, M. C., Strålfors, P., van Riel, N. A. W., Gennemark, P. & Cedersund, G., 6 Apr 2016, In : Interface Focus. 6, 2, 14 p., 20150075

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Medical problems
Type 2 Diabetes Mellitus
Pharmacology
Pharmaceutical Preparations
Meals
2015
2 Citations (Scopus)

A physiology-based model describing heterogeneity in glucose metabolism: the core of the Eindhoven Diabetes Education Simulator (E-DES)

Maas, A. H., Rozendaal, Y. J. W., van Pul, C., Hilbers, P. A. J., Cottaar, E. J. E., Haak, H. R. & Riel, van, N. A. W., Mar 2015, In : Journal of Diabetes Science and Technology. 9, 2, p. 282-292 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Physiology
Medical problems
Metabolism
Glucose
Simulators
12 Citations (Scopus)

A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation

Hijmans, B. S., Tiemann, C. A., Grefhorst, A., Boesjes, M., Dijk, van, T. H., Tietge, U. J. F., Kuipers, F., Riel, van, N. A. W., Groen, A. K. & Oosterveer, M. H., 2015, In : The FASEB Journal. 29, 4, p. 1153-1164

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Systems Biology
Fatty Liver
Liver
Chemical activation
Triglycerides
4 Citations (Scopus)

Effects of low-stearate palm oil and high-stearate lard high-fat diets on rat liver lipid metabolism and glucose tolerance

Janssens, S., Heemskerk, M. M., van den Berg, S. A., van Riel, N. A., Nicolaij, K., Willems van Dijk, K. & Prompers, J., 18 Dec 2015, In : Nutrition and Metabolism. 12, 1, p. 1-11 57

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Stearates
High Fat Diet
Lipid Metabolism
Glucose
Liver
5 Citations (Scopus)

Model-based quantification of the systemic interplay between glucose and fatty acids in the postprandial state

Sips, F., Nyman, E. E., Adiels, M., Hilbers, P., Strålfors, P., van Riel, N. & Cedersund, G., 10 Sep 2015, In : PLoS ONE. 10, 9, 20 p., e0135665

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
postprandial state
Fatty Acids
free fatty acids
fatty acids
Glucose
2014
8 Citations (Scopus)

A computational model for the analysis of Lipoprotein distributions in the mouse : translating FPLC profiles to Lipoprotein metabolism

Sips, F. L. P., Tiemann, C. A., Oosterveer, M. H., Groen, A. K., Hilbers, P. A. J. & Riel, van, N. A. W., 2014, In : PLoS Computational Biology. 10, 5, p. e1003579-1/17 17 p., e1003579

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Lipoproteins
Metabolism
lipoproteins
Computational Model
Mouse

Effect of caloric and non-caloric sweeteners on liver lipid metabolism in rats

Janssens, S., van Riel, N., Nicolaij, K. & Prompers, J., Apr 2014, In : The FASEB Journal. 28, 1 supplement, 642.5

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Incorporating the intake of meals in the Eindhoven Diabetes Education Simulator (E-DES)

Maas, A. H., Rozendaal, Y. J. W., van Pul, C., Cottaar, E. J. E., Hilbers, P. A. J., Haak, H. R. & van Riel, N. A. W., 1 Feb 2014, In : Diabetes Technology & Therapeutics. 16, p. A116

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Muscle-type specific autophosphorylation of CaMKII isoforms after paced contractions

Eilers, W., Gevers, W. B. L., Overbeek, van, D., Haan, de, A., Jaspers, R. T., Hilbers, P. A. J., Riel, van, N. A. W. & Flück, M., 2014, In : BioMed Research International. 2014, p. 943806-1/21 20 p., 943806

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Calcium-Calmodulin-Dependent Protein Kinases
Calmodulin
Protein Kinases
Muscle
Protein Isoforms
20 Citations (Scopus)

Optimal experiment design for model selection of biochemical networks

Vanlier, J., Tiemann, C. A., Hilbers, P. A. J. & Riel, van, N. A. W., 2014, In : BMC Systems Biology. 8, p. 20-1/16 16 p., 20

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Biochemical Networks
Model Selection
Experiment
Predictive Density
Experiments
2013
4 Citations (Scopus)

Applications of analysis of dynamic adaptations in parameter trajectories

Riel, van, N. A. W., Tiemann, C. A., Vanlier, J. & Hilbers, P. A. J., 2013, In : Interface Focus. 3, 2, p. 20120084-1/13 20120084

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Trajectories
Metabolome
Proteome
Transcriptome
Research
12 Citations (Scopus)

Combined in vivo and in silico investigation of activation of glycolysis in contracting skeletal muscle

Schmitz, J. P. J., Groenendaal, W., Wessels, B., Wiseman, R. W., Hilbers, P. A. J., Nicolay, K., Prompers, J. J., Jeneson, J. A. L. & Riel, van, N. A. W., 2013, In : American Journal of Physiology : Cell Physiology. 304, 2, p. C180-C193 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Glycolysis
Computer Simulation
Skeletal Muscle
Calmodulin
Calcium
12 Citations (Scopus)

Parameter trajectory analysis to identify treatment effects of pharmacological interventions

Tiemann, C. A., Vanlier, J., Oosterveer, M. H., Groen, A. K., Hilbers, P. A. J. & Riel, van, N. A. W., 2013, In : PLoS Computational Biology. 9, 8, p. e1003166-1/15 15 p., e1003166

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Treatment Effects
trajectories
Receptor
trajectory
Trajectories
44 Citations (Scopus)

Parameter uncertainty in biochemical models described by ordinary differential equations

Vanlier, J., Tiemann, C. A., Hilbers, C. W. & Riel, van, N. A. W., 2013, In : Mathematical Biosciences. 246, 2, p. 305-314

Research output: Contribution to journalArticleAcademicpeer-review

parameter uncertainty
Uncertainty analysis
Parameter Uncertainty
Ordinary differential equations
Uncertainty
2012
44 Citations (Scopus)

A Bayesian approach to targeted experiment design

Vanlier, J., Tiemann, C. A., Hilbers, P. A. J. & Riel, van, N. A. W., 2012, In : Bioinformatics. 28, 8, p. 1136-1142 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bayes Theorem
Bayesian Approach
Uncertainty
Experiment
Prediction
41 Citations (Scopus)

An integrated strategy for prediction uncertainty analysis

Vanlier, J., Tiemann, C. A., Hilbers, P. A. J. & Riel, van, N. A. W., 2012, In : Bioinformatics. 28, 8, p. 1130-1135

Research output: Contribution to journalArticleAcademicpeer-review

Uncertainty Analysis
Uncertainty analysis
Prediction Model
Uncertainty
Pathway
23 Citations (Scopus)

Prediction of muscle energy states at low metabolic rates requires feedback control of mitochondrial respiratory chain activity by inorganic phosphate

Schmitz, J. P. J., Jeneson, J. A. L., Oorschot, van, J. W. M., Prompers, J. J., Nicolay, K., Hilbers, P. A. J. & Riel, van, N. A. W., 2012, In : PLoS ONE. 7, 3, p. E34118-1/14 14 p., E34118

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
electron transport chain
Electron Transport
Electron energy levels
Feedback control
Muscle
2011
6 Citations (Scopus)

Computational modeling of mitochondrial energy transduction

Schmitz, J. P. J., Vanlier, J., Riel, van, N. A. W. & Jeneson, J. A. L., 2011, In : Critical Reviews in Biomedical Engineering. 39, 5, p. 363-377

Research output: Contribution to journalArticleAcademicpeer-review

Mitochondria
Physiology
Oils and fats
Sugars
Free energy
16 Citations (Scopus)

Parameter adaptations during phenotype transitions in progressive diseases

Tiemann, C. A., Vanlier, J., Hilbers, P. A. J. & Riel, van, N. A. W., 2011, In : BMC Systems Biology. 5, p. 174-1/14 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Parameter Adaptation
Phenotype
Cholesterol
Biological systems
Biological Systems
2010
24 Citations (Scopus)

Quantifying the composition of human skin for glucose sensor development

Groenendaal, W., Von Basum, G., Schmidt, K. A., Hilbers, P. A. J. & van Riel, N. A. W., 1 Jan 2010, In : Journal of Diabetes Science and Technology. 4, 5, p. 1032-1040 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Glucose sensors
Skin
Glucose
Chemical analysis
Adipose Tissue

Regulation of force dynamics in fast twitch muscle

Groenendaal, W., Jeneson, J. A. L., Wiseman, R. W., Nicolaij, K., Hilbers, P. A. J. & Riel, van, N. A. W., 2010, In : The FASEB Journal. 24, p. 801.1-

Research output: Contribution to journalArticleAcademicpeer-review

Muscle
Tetanus
Chemical activation
Calcium
Muscles
14 Citations (Scopus)

Silencing of glycolysis in muscle : experimental observation and numerical analysis

Schmitz, J. P. J., Riel, van, N. A. W., Nicolay, K., Hilbers, P. A. J. & Jeneson, J. A. L., 2010, In : Experimental Physiology. 95, 2, p. 380-397

Research output: Contribution to journalArticleAcademicpeer-review

Glycolysis
Phosphofructokinases
Pyruvate Kinase
Hexoses
Muscle Contraction
48 Citations (Scopus)

The influence of temporal resolution in determining pharmacokinetic parameters from DCE-MRI data

Heisen, M., Fan, X., Buurman, J., Riel, van, N. A. W., Karczmar, G. S. & Haar Romenij, ter, B. M., 2010, In : Magnetic Resonance in Medicine. 63, 3, p. 811-816 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacokinetics
Gadolinium
Extracellular Space
Contrast Media
Genetic Recombination
18 Citations (Scopus)

The use of a reference tissue arterial input function with low-temporal-resolution DCE-MRI data

Heisen, M., Fan, X., Buurman, J., Riel, van, N. A. W., Karczmar, G. S. & Haar Romeny, ter, B. M., 2010, In : Physics in Medicine and Biology. 55, 16, p. 4871-4883

Research output: Contribution to journalArticleAcademicpeer-review

Magnetic Resonance Imaging
Pharmacokinetics
Rodentia
Breast
Neoplasms
2009

Analysis of tumor texture on a pre-treatment CT scan predicts treatment outcome in NSCLC patients

Rios Velazquez, E., Aerts, H., Dehing-Oberije, C., Petit, S. F., Eikelder, ten, H. M. M., Ruysscher, de, D., Riel, van, N. A. W. & Lambin, P., 2009, In : European Journal of Cancer. 7, S2, p. 522-523

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Neoplasms
Therapeutics
39 Citations (Scopus)

Intra-voxel heterogeneity influences the dose prescription for dose-painting with radiotherapy: a modelling study

Petit, S. F., Dekker, A. L. A. J., Seigneuric, R., Murrer, L. H. P., Riel, van, N. A. W., Nordsmark, M., Overgaard, J., Lambin, P. & Wouters, B. G., 2009, In : Physics in Medicine and Biology. 54, 7, p. 2179-2196

Research output: Contribution to journalArticleAcademicpeer-review

Paintings
Prescriptions
Radiotherapy
Oxygen
Neoplasms
32 Citations (Scopus)

Magnitude and control of mitochondrial sensitivity to ADP

Jeneson, J. A. L., Schmitz, J. P. J., Broek, van den, N. M. A., Riel, van, N. A. W., Hilbers, P. A. J., Nicolay, K. & Prompers, J. J., 2009, In : American Journal of Physiology : Endocrinology and Metabolism. 297, 3, p. E774-E784 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Adenosine Diphosphate
Phosphocreatine
Adenosine Triphosphate
Muscles
Computer Simulation
22 Citations (Scopus)

Reliability of pharmacokinetic parameters: small versus medium-sized contrast agents

Jaspers, K., Aerts, H., Leiner, T., Oostendorp, M., Riel, van, N. A. W., Post, M. J. & Backes, W. H., 2009, In : Magnetic Resonance in Medicine. 62, 3, p. 779-787

Research output: Contribution to journalArticleAcademicpeer-review

Contrast Media
Pharmacokinetics
Computer Simulation
2008
6 Citations (Scopus)

Computational modelling identifies impact of subtle anatomical variations between amphibian and mammalian skeletal muscle on spatiotemporal calcium dynamics

Groenendaal, W., Jeneson, J. A. L., Verhoog, P. J., Riel, van, N. A. W., Eikelder, ten, H. M. M., Nicolay, K. & Hilbers, P. A. J., 2008, In : IET Systems Biology. 2, 6, p. 411-422

Research output: Contribution to journalArticleAcademicpeer-review

Skeletal muscle
Computational Modeling
Amphibians
Calcium
Muscle
3 Citations (Scopus)

Mathematical modeling of the calcium-left ventricular pressure relationship in the intact diabetic rat heart

Op den Buijs, J., Ligeti, L., Ivanics, T., Miklós, Z., Vusse, van der, G. J. & Riel, van, N. A. W., 2008, In : Acta Physiologica. 193, 3, p. 205-217 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ventricular Pressure
Troponin C
Myofibrils
Calcium
Isoproterenol