Projects per year
Personal profile
Academic background
Miguel Castilho is an Associate Professor of Biomaterial engineering and Biofabrication at TU/e. He holds a MSc degree in Mechanical Engineering and a PhD in Biomedical engineering (cum laude) from the University of Lisbon (IST, Portugal). During his PhD studies he was a visiting researcher at Department for Functional Materials in Medicine and Dentistry, University of Würzburg (Germany), focusing on engineering Bioactive inorganic materials and bone bioengineering. From 2015 - 2018, he was a post-doctoral research fellow in Biofabrication at the University Medical Center Utrecht (UMC Utrecht, The Netherlands). In 2018, he become an Assistant professor at UMC Utrecht and at the Regenerative Medicine Center (The Netherlands), a role he held until 2021. In 2021, he started a tenured position as an Assistant Professor in the Department of Biomedical Engineering at TU/e, while maintaining an adjunct appointment in Biofabrication at UMC Utrecht. In 2024, he was appointed Associate Professor at TU/e
Research profile
Development of design & fabrication technologies that enable the local control of (bio) material composition and structure across multiple length scales is fundamental to understand complex regenerative processes in the human body; as well as to develop approaches for functional restoration of damaged&diseased tissues and organs. To address this challenge, Castilho team uses a material-by-design approach, combining advanced 3D printing technologies and computational design, to develop instructive materials for regenerative medicine, particularly of musculoskeletal tissues, like bone. Castilho’s research is interdisciplinary, bringing together engineers, materials scientists and cell biologists. An important focus area of the team is on exploring opportunities for translation of instructive materials in human clinics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Editorial Board, Biomaterial Advances
2024 → …
Editorial Board, In vitro models
2024 → …
Communications & Outreach Committee Member, Tissue Engineering & Regenerative medicine – European Chapter
2024 → …
Scientific Leadership Committee, International Society of Bone Morphometry
2023 → …
Adjunct Assistant Professor, UMC Utrecht
1 Dec 2021 → …
Assistant Professor, UMC Utrecht
15 May 2018 → …
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Advaessel: Ad vanced materials processing and design for regenerating blodd vessels
Kurniawan, N. A. (Project Manager) & Castilho, M. (Project member)
1/11/20 → 30/11/21
Project: Research direct
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Meta-adaptive biomaterials: multiscale, spatiotemporal organization and actuation in engineered tissues
Cedillo-Servin, G., Al-Jehani, E. A. A., Rossy, T., Teixeira, S. P. B., Sage, F., Domingues, R. M. A., Raman, R. & Castilho, M. (Corresponding author), 4 Jun 2025, (E-pub ahead of print) In: Trends in Biotechnology. XX, XResearch output: Contribution to journal › Review article › peer-review
Open Access -
Thermoforming for Small Feature Replication in Melt Electrowritten Membranes to Model Kidney Proximal Tubule
Valverde, M. G. (Corresponding author), Stampa Zamorano, C., Kožinec, D., Benito Zarza, L., van Genderen, A. M., Janssen, R., Castilho, M., Hrynevich, A., Vermonden, T., Malda, J., de Ruijter, M., Masereeuw, R. & Mihăilă, S. M. (Corresponding author), Jan 2025, In: Advanced Healthcare Materials. 14, 1, 13 p., 2401800.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Downloads (Pure) -
Xolography for Biomedical Applications: Dual-Color Light-Sheet Printing of Hydrogels With Local Control Over Shape and Stiffness
Stoecker, L., Cedillo-Servin, G., König, N. F., de Graaf, F. V., García-Jiménez, M., Hofmann, S., Ito, K., Wentzel, A. S. & Castilho, M. (Corresponding author), 12 Mar 2025, In: Advanced Materials. 37, 10, 16 p., 2410292.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)15 Downloads (Pure) -
3D Printed Magneto-Active Microfiber Scaffolds for Remote Stimulation and Guided Organization of 3D In Vitro Skeletal Muscle Models
Cedillo-Servin, G., Dahri, O., Meneses, J., van Duijn, J., Moon, H., Sage, F., Silva, J., Pereira, A., Magalhães, F. D., Malda, J., Geijsen, N., Pinto, A. M. & Castilho, M. (Corresponding author), 22 Mar 2024, In: Small. 20, 12, 15 p., 2307178.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Citations (Scopus)67 Downloads (Pure) -
Covalent Grafting of Functionalized MEW Fibers to Silk Fibroin Hydrogels to Obtain Reinforced Tissue Engineered Constructs
Viola, M., Ainsworth, M. J., Mihajlovic, M., Cedillo-Servin, G., van Steenbergen, M. J., van Rijen, M., de Ruijter, M., Castilho, M., Malda, J. & Vermonden, T. (Corresponding author), 11 Mar 2024, In: Biomacromolecules. 25, 3, p. 1563-1577 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)56 Downloads (Pure)
Prizes
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Jean Leray Award
Castilho, M. (Recipient), 2023
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific