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Miguel Castilho is an Assistant Professor of Biomaterials design and processing at TU/e. He holds a MSc degree in Mechanical Engineering and a PhD in Biomedical engineering (cum laude) from the University of Lisbon (IST, Portugal). During his PhD studies he was a visiting researcher at Department for Functional Materials in Medicine and Dentistry, University of Würzburg (Germany), in the field of Bioactive inorganic materials design and 3D printing. From 2015 - 2018 he was a post-doctoral research fellow in 3D Printing and Biofabrication at the University Medical Center Utrecht (UMC Utrecht, The Netherlands), to become an Assistant professor at UMC Utrecht and at the Regenerative Medicine Center (The Netherlands) from 2018 – 2021. In 2021 he started a tenured position as an Assistant Professor in the Department of Biomedical Engineering at TU/e, and holds an adjunct appointment in Biofabrication at UMC Utrecht.
Development of design & fabrication technologies that enable the local control of (bio) material composition and structure across multiple length scales is fundamental to understand complex regenerative processes in the human body; as well as to develop approaches for functional restoration of damaged&diseased tissues and organs. To address this challenge, Castilho team uses a material-by-design approach, combining advanced 3D printing technologies and computational design, to develop instructive materials for regenerative medicine, particularly of musculoskeletal tissues, like bone. Castilho’s research is interdisciplinary, bringing together engineers, materials scientists and cell biologists. An important focus area of the team is on exploring opportunities for translation of instructive materials in human clinics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Adjunct Assistant Professor, UMC Utrecht
1 Dec 2021 → …
Assistant Professor, Universitair Medisch Centrum Utrecht
15 May 2018 → …
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- 1 Finished
1/11/20 → 30/11/21
Project: Research direct
Rikkers, M., Nguyen, H. C., Golafshan, N., de Ruijter, M., Levato, R., Vonk, L. A., van Egmond, N., Castilho, M., Custers, R. J. H. & Malda, J., 2023, (Accepted/In press) In: Journal of Cartilage and Joint Preservation. XX, X, 100117.
Research output: Contribution to journal › Article › Academic › peer-reviewOpen Access
Composite Graded Melt Electrowritten Scaffolds for Regeneration of the Periodontal Ligament-to-Bone InterfaceGolafshan, N., Castilho, M., Daghrery, A., Alehosseini, M., van de Kemp, T., Krikonis, K., de Ruijter, M., Dal-Fabbro, R., Dolatshahi-Pirouz, A., Bhaduri, S. B., Bottino, M. C. & Malda, J., 15 Mar 2023, In: ACS Applied Materials and Interfaces. 15, 10, p. 12735–12749 15 p.
Research output: Contribution to journal › Article › Academic › peer-reviewOpen AccessFile1 Downloads (Pure)
Convergence of melt electrowriting and extrusion-based bioprinting for vascular patterning of a myocardial constructAinsworth, M. J., Chirico, N., de Ruijter, M., Hrynevich, A., Dokter, I., Sluijter, J. P. G., Malda, J., van Mil, A. & Castilho, M., 1 Jul 2023, In: Biofabrication. 15, 3, 15 p., 035025.
Research output: Contribution to journal › Article › Academic › peer-reviewOpen AccessFile4 Downloads (Pure)
Ainsworth, M. J., Lotz, O., Gilmour, A., Zhang, A., Chen, M. J., McKenzie, D. R., Bilek, M. M. M., Malda, J., Akhavan, B. & Castilho, M., 10 Jan 2023, In: Advanced Functional Materials. 33, 2, 14 p., 2206583.
Research output: Contribution to journal › Article › Academic › peer-reviewOpen AccessFile
Load-induced fluid pressurisation in hydrogel systems before and after reinforcement by melt-electrowritten fibrous meshesMoo, E. K., Ebrahimi, M., Hrynevich, A., de Ruijter, M., Castilho, M., Malda, J. & Korhonen, R. K., Jul 2023, In: Journal of the Mechanical Behavior of Biomedical Materials. 143, 12 p., 105941.
Research output: Contribution to journal › Article › Academic › peer-review
1/09/13 → …
1/09/12 → 31/08/25
1/09/12 → …