• 3801 Citations
1989 …2020

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2020

Continuous small-molecule monitoring with a digital single particle switch

Yan, J., van Smeden, L., Merkx, M., Zijlstra, P. & Prins, M. W. J., 24 Apr 2020, In : ACS Sensors. 5, 4, p. 1168-1176 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multiplexed continuous biosensing by single-molecule encoded nanoswitches

Lubken, R. M., de Jong, A. M. & Prins, M. W. J., 8 Apr 2020, In : Nano Letters. 20, 4, p. 2296-2302 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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18 Downloads (Pure)
2019

Conformation switching of single native proteins revealed by nanomechanical probing without a pulling force

Gutierrez Mejia, F. A., Moerland, C., van Ijzendoorn, L. & Prins, M., 14 Nov 2019, In : Nanoscale. 11, 42, p. 19933-19942 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
25 Downloads (Pure)

Rate of dimer formation in stable colloidal solutions quantified using an attractive interparticle force

Scheepers, M. R. W., Romijn, A. R., van IJzendoorn, L. J. & Prins, M. W. J., 13 Aug 2019, In : Langmuir. 35, 32, p. 10533-10541 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
26 Downloads (Pure)

Single-dimer formation rate reveals heterogeneous particle surface reactivity

Scheepers, M. R. W., van IJzendoorn, L. J. & Prins, M. W. J., 13 Oct 2019, In : Langmuir. 35, 44, p. 14272-14281 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
18 Downloads (Pure)
2018

Continuous biomarker monitoring by particle mobility sensing with single molecule resolution

Visser, E. W. A., Yan, J., van IJzendoorn, L. J. & Prins, M. W. J., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 2541.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
13 Citations (Scopus)
95 Downloads (Pure)

Nanoscale interparticle distance within dimers in solution measured by light scattering

van Vliembergen, R. W. L., van Ijzendoorn, L. J. & Prins, M. W. J., 9 Jan 2018, In : Langmuir. 34, 1, p. 179-186 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
169 Downloads (Pure)
2017

How actuated particles effectively capture biomolecular targets

van Reenen, A., de Jong, A. M. & Prins, M. W. J., 21 Mar 2017, In : Analytical Chemistry. 89, 6, p. 3402-3410 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
85 Downloads (Pure)

Interparticle capillary forces at a fluid−fluid interface with strong polymer-induced aging

Cappelli, S., de Jong, A. M., Baudry, J. & Prins, M. W. J., 24 Jan 2017, In : Langmuir. 33, 3, p. 696–705 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)
87 Downloads (Pure)

The influence of covalent immobilization conditions on antibody accessibility on nanoparticles

Saha, B., Songe, P., Evers, T. H. & Prins, M. W. J., 21 Nov 2017, In : Analyst. 142, 22, p. 4247-4256 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
17 Citations (Scopus)
272 Downloads (Pure)
2016

Distance within colloidal dimers probed by rotation-induced oscillations of scattered light

van Vliembergen, R. W. L., van IJzendoorn, L. J. & Prins, M. W. J., 25 Jan 2016, In : Optics Express. 24, 2, p. A123-A138

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
217 Downloads (Pure)

Evanescent field biosensor using polymer slab waveguide-based cartridges for the optical detection of nanoparticles

Teigell Beneitez, N., Missinne, J., Visser, E. W. A., Van Ijzendoorn, L. J., Prins, M. W. J., Schleipen, J. J. H. B., Vinkenborg, J. L., Rietjens, G., Verschuuren, M. A., Krishnamoorthy, G., Orsel, J. G. & Van Steenberge, G., 1 May 2016, In : IEEE Journal of Selected Topics in Quantum Electronics. 22, 3, p. 1-8

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
3 Downloads (Pure)

Interfacial rheometry of polymer at a water-oil interface by intra-pair magnetophoresis

Cappelli, S., de Jong, A. M., Baudry, J. & Prins, M. W. J., 17 May 2016, In : Soft Matter. 12, p. 5551-5562 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
3 Downloads (Pure)

Mechanical properties of single supramolecular polymers from correlative AFM and fluorescence microscopy

Beuwer, M. A., Knopper, M. F., Albertazzi, L., van der Zwaag, D., Ellenbroek, W. G., Meijer, E. W., Prins, M. W. J. & Zijlstra, P., 8 Nov 2016, In : Polymer Chemistry. 7, 47, p. 7260-7268 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
13 Downloads (Pure)

Particle motion analysis reveals nanoscale bond characteristics and enhances dynamic range for biosensing

Visser, E. W. A., van IJzendoorn, L. J. & Prins, M. W. J., 22 Mar 2016, In : ACS Nano. 10, 3, p. 3093-3101 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
9 Downloads (Pure)

Single-bond association kinetics determined by tethered particle motion: concept and simulations

Merkus, K. E., Prins, M. W. J. & Storm, C., 18 Oct 2016, In : Biophysical Journal. 111, 8, p. 1612–1620

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
108 Downloads (Pure)

Strong reduction of spectral heterogeneity in gold bipyramids for single-particle and single-molecule plasmon sensing

Peters, S. M. E., Verheijen, M. A., Prins, M. W. J. & Zijlstra, P., 15 Jan 2016, In : Nanotechnology. 27, 2, 7 p., 024001.

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)
8 Downloads (Pure)
2015

Ara h 1 protein–antibody dissociation study : evidence for binding inhomogeneities on a molecular scale

Perez-Ruiz, E., Spasic, D., Gils, A., IJzendoorn, van, L. J., Prins, M. W. J. & Lammertyn, J., 2015, In : New Biotechnology. 32, 5, p. 458-466 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
2 Downloads (Pure)

Dynamic wetting : status and prospective of single particle based experiments and simulations

Cappelli, S., Xie, Q., Harting, J. D. R., Jong, de, A. M. & Prins, M. W. J., 2015, In : New Biotechnology. 32, 5, p. 420-432 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
11 Citations (Scopus)
80 Downloads (Pure)

Gurus of single molecule detection

Duffy, D., Landegren, U., Oijen, van, A. & Prins, M. W. J., 2015, In : The Analytical Scientist. 28, p. 36-42 7 p.

Research output: Contribution to journalArticleProfessional

2 Downloads (Pure)

Molecular interference in antibody–antigen interaction studied with magnetic force immunoassay

Dorokhin, D. V., IJzendoorn, van, L. J., Jong, de, A. M., Nieto, L., Brunsveld, L., Orsel, J. G. & Prins, M. W. J., 2015, In : New Biotechnology. 32, 5, p. 450-457 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2 Downloads (Pure)

Stochastic protein interactions monitored by hundreds of single-molecule plasmonic biosensors

Beuwer, M. A., Prins, M. W. J. & Zijlstra, P., 2015, In : Nano Letters. 15, 5, p. 3507-3511

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
74 Citations (Scopus)
68 Downloads (Pure)

Strong vortical flows generated by the collective motion of magnetic particle chains rotating in a fluid cell

Gao, Y., Beerens, J., Reenen, van, A., Hulsen, M. A., Jong, de, A. M., Prins, M. W. J. & Toonder, den, J. M. J., 2015, In : Lab on a Chip. 15, p. 351-360 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
12 Downloads (Pure)

Surfactants modify the torsion properties of proteins : a single molecule study

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2015, In : New Biotechnology. 32, 5, p. 441-449 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
8 Downloads (Pure)

Transportation, dispersion and ordering of dense colloidal assemblies by magnetic interfacial rotaphoresis

Reenen, van, A., Jong, de, A. M. & Prins, M. W. J., 2015, In : Lab on a Chip. 15, p. 2864-2871 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
2014

Biology becomes digital

Prins, M. W. J., 2014, In : ICMS Highlights. 2, March 2014, p. 4-6 3 p.

Research output: Contribution to journalArticlePopular

Open Access
File
56 Downloads (Pure)

Chaotic fluid mixing by alternating microparticle topologies to enhance biochemical reactions

Gao, Y., Reenen, van, A., Hulsen, M. A., Jong, de, A. M., Prins, M. W. J. & Toonder, den, J. M. J., 2014, In : Microfluidics and Nanofluidics. 16, 1-2, p. 265-274 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)
3 Downloads (Pure)

Dynamics of magnetic particles near a surface : model and experiments on field-induced disaggregation

van Reenen, A., Gao, Y., de Jong, A., Hulsen, M. A., den Toonder, J. M. J. & Prins, M. W. J., 22 Apr 2014, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 89, 4, p. 042306-1/10 10 p., 042306.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
36 Citations (Scopus)
129 Downloads (Pure)

How antibody surface coverage on nanoparticles determines the activity and kinetics of antigen capturing for biosensing

Saha, B., Evers, T. H. & Prins, M. W. J., 2014, In : Analytical Chemistry. 86, 16, p. 8158-66

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
74 Citations (Scopus)
235 Downloads (Pure)

Influence of dsDNA fragment length on particle binding in an evanescent field biosensing system

Koets, M., van Ommering, K., Wang, L., Testori, E., Evers, T. H. & Prins, M. W. J., 2014, In : Analyst. 139, p. 1672-1677 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
76 Downloads (Pure)

Integrated lab-on-chip biosensing systems based on magnetic particle actuation : a comprehensive review

Reenen, van, A., Jong, de, A. M., Toonder, den, J. M. J. & Prins, M. W. J., 2014, In : Lab on a Chip. 2014, 12, p. 1966-1986

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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152 Citations (Scopus)
341 Downloads (Pure)

Probing cell membrane mechanics by magnetic particle actuation and 3D rotational particle tracking

Irmscher, M., Jong, de, A. M., Kress, H. & Prins, M. W. J., 2014, In : Biophysical Journal. 106, 2, suppl. 1, p. 43a 1 p.

Research output: Contribution to journalArticleAcademic

Open Access
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51 Downloads (Pure)

Probing the force-induced dissociation of aptamer-protein complexes

Perez-Ruiz, E., Kemper, M., Spasic, D., Gils, A., IJzendoorn, van, L. J., Lammertyn, J. & Prins, M. W. J., 2014, In : Analytical Chemistry. 86, 6, p. 3084-3091

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
10 Citations (Scopus)
140 Downloads (Pure)

Quantification of platelet-surface interactions in real-time using intracellular calcium signaling

Zijp, van, H. M., Barendregt, A. D., Riegman, J., Goudsmits, J. M. H., Jong, de, A. M., Kress, H. & Prins, M. W. J., 2014, In : Biomedical Microdevices. 16, 2, p. 217-227 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
3 Downloads (Pure)
2013

Accelerated particle-based target capture : the roles of volume transport and near-surface alignment

Reenen, van, A., Jong, de, A. M. & Prins, M. W. J., 2013, In : Journal of Physical Chemistry B. 117, 5, p. 1210-1218 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Accurate quantification of magnetic particle properties by intra-pair magnetophoresis for nanobiotechnology

Reenen, van, A., Gao, Y., Bos, A. H., Jong, de, A. M., Hulsen, M. A., Toonder, den, J. M. J. & Prins, M. W. J., 2013, In : Applied Physics Letters. 103, 4, p. 043704-1/5 5 p., 043704.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
9 Citations (Scopus)
156 Downloads (Pure)

A method for time-resolved measurements of the mechanics of phagocytic cups

Irmscher, M., Jong, de, A. M., Kress, H. & Prins, M. W. J., 6 May 2013, In : Journal of Royal Society Interface. 10, 82, 9 p., 20121048.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
1 Downloads (Pure)

Circulating biomarkers for predicting cardiovascular disease risk : a systematic review and comprehensive overview of meta-analyses

Holten, van, T. C., Waanders, L. F., Groot, de, P. G., Vissers, J., Hoefer, I. E., Pasterkamp, G., Prins, M. W. J. & Roest, M., 2013, In : PLoS ONE. 8, p. e62080-1/8 8 p., e62080.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
62 Citations (Scopus)
107 Downloads (Pure)

Correction to accelerated particle-based target capture : the roles of volume transport and near-surface alignment

Reenen, van, A., Jong, de, A. M. & Prins, M. W. J., 2013, In : Journal of Physical Chemistry B. 117, 22, p. 6856-6856 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
78 Downloads (Pure)

Disaggregation of microparticle clusters by induced magnetic dipole-dipole repulsion near a physical surface

Gao, Y., Reenen, van, A., Hulsen, M. A., Jong, de, A. M., Prins, M. W. J. & Toonder, den, J. M. J., 2013, In : Lab on a Chip. 13, 7, p. 1394-1401

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)

Magneto-capillary valve for integrated purification and enrichment of nucleic acids and proteins

Dulk, den, R. C., Schmidt, K. A., Sabatté, G. S., Liebana, S. & Prins, M. W. J., 2013, In : Lab on a Chip. 13, 1, p. 106-118 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

50 Citations (Scopus)
1 Downloads (Pure)

The influence of inhomogeneous adhesion on the detachment dynamics of adhering cells

Irmscher, M., Laarhoven, van, K. A., Jong, de, A. M. & Prins, M. W. J., 2013, In : European Biophysics Journal. 42, p. 419-426 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
2 Downloads (Pure)

Torsion profiling of proteins using magnetic particles

Reenen, van, A., Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, In : Biophysical Journal. 104, 5, p. 1073-1080

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
3 Downloads (Pure)
2012

Interactions between protein coated particles and polymer surfaces studied with the rotating particles probe

Kemper, M., Spridon, D., IJzendoorn, van, L. J. & Prins, M. W. J., 2012, In : Langmuir. 28, 21, p. 8149-8155 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
1 Downloads (Pure)

Measurement of platelet responsiveness using antibody-coated magnetic beads for lab-on-chip applications

Zijp, van, H. M., Schot, C. C. M. M., Jong, de, A. M., Jongmans, N., Holten, van, T. C., Roest, M. & Prins, M. W. J., 2012, In : Platelets. 23, 8, p. 626-632

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2 Downloads (Pure)

One-step homogeneous magnetic nanoparticle immunoassay for biomarker detection directly in blood plasma

Ranzoni, A., Sabatté, G. S., IJzendoorn, van, L. J. & Prins, M. W. J., 2012, In : ACS Nano. 6, 4, p. 3134-3141 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

99 Citations (Scopus)
7 Downloads (Pure)

Probing the cell membrane by magnetic particle actuation and Euler angle tracking

Irmscher, M., Jong, de, A. M., Kress, H. & Prins, M. W. J., 2012, In : Biophysical Journal. 102, 3, p. 698-708 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)
1 Downloads (Pure)

Quantification of protein-ligand dissociation kinetics in heterogeneous affinity assays

Jacob, A., IJzendoorn, van, L. J., Jong, de, A. M. & Prins, M. W. J., 2012, In : Analytical Chemistry. 84, 21, p. 9287-9294 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)
2 Downloads (Pure)
2011

Frequency-selective rotation of two-particle nanoactuators for rapid and sensitive detection of biomolecules

Ranzoni, A., Schleipen, J. J. H. B., IJzendoorn, van, L. J. & Prins, M. W. J., 2011, In : Nano Letters. 11, 5, p. 2017-2022

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)
5 Downloads (Pure)

Protein biomarker enrichment by biomarker antibody complex elution for immunoassay biosensing

Sabatté, G. S., Feitsma, H., Evers, T. H. & Prins, M. W. J., 2011, In : Biosensors and Bioelectronics. 29, 1, p. 18-22

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
1 Downloads (Pure)