Projects per year
Personal profile
Quote
"Molecular biosensors for continuous patient monitoring will help to make healthcare truly personal"
Research profile
With his research group, Menno Prins aims at the development of technologies to detect proteins and study protein function with single-molecule resolution in complex macromolecular environments such as blood plasma. This entails the investigation of biophysical manipulation and detection methods with emphasis on the use of small particles. These particles offer the possibility to actively transport biological materials and to detect the presence and properties of specific targets.
The capability to probe individual molecules enables the researchers to reveal novel characteristics of the molecules, e.g. distributions of molecular properties (such as affinity or kinetic parameters, variations in space and/or in time). Moreover, it allows the study of properties that are difficult or even impossible to measure on ensembles of molecules, e.g. molecular torsion constants. The research of the MBx group leads to novel biosensing technologies and to a better understanding of molecular functions within complex and crowded environments.
Menno Prins is the founder and organizer of SensUs, the annual international student competition in the field of bioensors for health (www.sensus.org). SensUs serves as a platform to accelerate education and innovation in the field of biosensing, with participation of international academic research groups, companies, and healthcare organizations.
The research activities are part of the Institute for Complex Molecular Systems (ICMS) and the Strategic Area Health (SA Health).
Academic background
Menno Prins studied Applied Physics at Université Paris XI and Delft University of Technology where he obtained his MSc degree cum laude. He received his PhD from Radboud University Nijmegen in 1995. He then moved to Philips Research where he worked on microfluidics and point-of-care biosensing. In 2005, he was appointed as part-time professor at Eindhoven University of Technology in the department of Applied Physics. In 2014, he was appointed full Professor in Molecular Biosensing for Medical Diagnostics in the departments of BioMedical Engineering and Applied Physics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Network
Projects
- 1 Active
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Real-time Biomolecular Sensing for Smart Food Industry
Prins, M. W. J., Michielsen, C. M. S. & Vu, C.
1/05/21 → 21/12/26
Project: Research direct
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Continuous biomarker monitoring with single molecule resolution by measuring free particle motion
Buskermolen, A. D., Lin, Y-T., van Smeden, L., van Haaften, R. B., Yan, J., Sergelen, K., de Jong, A. M. & Prins, M. W. J., 13 Oct 2022, In: Nature Communications. 13, 1, 6052.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)14 Downloads (Pure) -
Real-Time Monitoring of Biomolecules: Dynamic Response Limits of Affinity-Based Sensors
Lubken, R. M., de Jong, A. M. & Prins, M. W. J., 28 Jan 2022, In: ACS Sensors. 7, 1, p. 286-295 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)65 Downloads (Pure) -
Reversible Immunosensor for the Continuous Monitoring of Cortisol in Blood Plasma Sampled with Microdialysis
van Smeden, L., Saris, A., Sergelen, K., de Jong, A. M., Yan, J. & Prins, M. W. J., 28 Oct 2022, In: ACS Sensors. 7, 10, p. 3041-3048 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Downloads (Pure) -
Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU: results from the international A- TEAMICU survey
Lanckohr, C., Boeing, C., De Waele, J. J., de Lange, D. W., Schouten, J., Prins, M., Nijsten, M., Povoa, P., Morris, A. C. & Bracht, H., 26 Aug 2021, In: Annals of Intensive Care. 11, 1, 8 p., 131.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)24 Downloads (Pure) -
Click-Coupling to Electrostatically Grafted Polymers Greatly Improves the Stability of a Continuous Monitoring Sensor with Single-Molecule Resolution
Lin, Y. T., Vermaas, R., Yan, J., de Jong, A. M. & Prins, M. W. J., 28 May 2021, In: ACS Sensors. 6, 5, p. 1980-1986 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)38 Downloads (Pure)
Datasets
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Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU: results from the international A- TEAMICU survey
Lanckohr, C. (Creator), Boeing, C. (Creator), De Waele, J. J. (Creator), de Lange, D. W. (Creator), Schouten, J. (Creator), Prins, M. W. J. (Creator), Nijsten, M. (Creator), Povoa, P. (Creator), Morris, A. C. (Creator) & Bracht, H. (Creator), Figshare, 27 Aug 2021
DOI: 10.6084/m9.figshare.c.5585799
Dataset
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Lecture during Summer School UAB, Barcelona, Spain
Menno W.J. Prins (Invited speaker)
30 Jun 2014Activity: Talk or presentation types › Invited talk › Scientific
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Physics@FOM Veldhoven 2013, January 22-23, 2013, Veldhoven, The Netherlands
Menno W.J. Prins (Invited speaker)
22 Jan 2013Activity: Talk or presentation types › Invited talk › Scientific
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International Symposium Technologies for Diagnostics, 22 October 2012, Uppsala, Sweden
Menno W.J. Prins (Invited speaker)
22 Oct 2012Activity: Talk or presentation types › Invited talk › Scientific
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Symposium Bossche Chemische Kring, 8 Mei 2012, Den Bosch, Nederland, 's-Hertogenbosch
Menno W.J. Prins (Speaker)
8 May 2012Activity: Talk or presentation types › Contributed talk › Scientific
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Workshop ITN (International Training Network) BioMaX, 13 February 2012, Eindhoven, The Netherlands
Menno W.J. Prins (Speaker)
13 Feb 2012Activity: Talk or presentation types › Contributed talk › Scientific
Courses
Press / Media
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Findings on Hematology Detailed by Investigators at Eindhoven University of Technology (Reversible Immunosensor for the Continuous Monitoring of Cortisol In Blood Plasma Sampled With Microdialysis)
Menno W.J. Prins & Junhong Yan
25/11/22
1 item of Media coverage
Press/Media: Expert Comment
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Continuous biomarker monitoring with single molecule resolution by measuring free particle motion
19/10/22
3 items of Media coverage
Press/Media: Expert Comment
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-Eindhoven University of Technology : Get ready for the biosensor future
Leo J. van IJzendoorn & Menno W.J. Prins
8/11/21
1 item of Media coverage
Press/Media: Expert Comment
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Get ready for the biosensor future
Leo J. van IJzendoorn & Menno W.J. Prins
5/11/21
1 item of Media coverage
Press/Media: Expert Comment
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Eindhoven University of Technology Students Launch Competition to Develop Biosensors That Quickly Measure Flu in Saliva
Menno W.J. Prins & B. Fitzgerald
27/08/21
1 item of Media coverage
Press/Media: Expert Comment