Projects per year
Personal profile
Quote
“L’invenzione è l’attimo in cui con la tua conoscenza torni bambino – invention is a moment when with our knowledge we are children again.”
Research profile
Massimo Mischi is professor of biomedical signal processing and chairs the Signal Processing Systems (SPS) Division within the Electrical Engineering Faculty of the Eindhoven University of Technology (TU/e). With over 250 researchers, SPS is the largest division at TU/e. Within the SPS Division, he founded the Biomedical Diagnostics (BM/d) Lab in 2012, with focus on biomedical signal processing and analysis for improved patient diagnostics and monitoring. Today, the BM/d Lab comprises 180 researchers and several clinical and industrial advisors.
Prof. Mischi’s research focuses on the analysis of biomedical signals, with applications ranging from electrophysiology to diagnostic imaging. His approach emphasizes modeling the complete measurement chain, from (patho)physiological sources to sensor physics and ultimately to diagnostic interpretation. This approach bridges data-driven and physics-driven biosignal analysis, enabling more accurate and explainable diagnostics while reducing data volumes and computational complexity.
In recognition of his research contributions, he has been invited to deliver about 90 lectures at international conferences worldwide, spanning both technical and clinical audiences. Notable among these are the EUROSON Keynote Lecture in 2017 and the keynote at TU/e’s 57th academic anniversary (Dies Natalis) in 2013. Together with his students and collaborators, he received two Martin Black Awards for Best Paper in Physiological Measurement (2008, 2018), >30 awards at international conferences, and many co-authored papers that received editorial distinctions from journals including IEEE T-MI, IEEE T-UFFC, IEEE T-BME.
His scientific output includes >230 peer-reviewed journal articles (> 9000 citations), one book (plus one book foreword), 15 book chapters, and over 400+ conference contributions. His work has led to 17 patents and patent applications and has been implemented in various commercial software platforms. He is also the co-founder of three startup companies.
Beyond his roles at the SPS Division and BM/d Lab, he has actively contributed to various national and international scientific communities. He is the co-founder and former chairman of the IEEE-EMBS Benelux Chapter and served as a board member of the Urological Imaging Section of the European Association of Urology. He currently chairs the Safety Committee of the World Federation for Ultrasound in Medicine and Biology, serves as secretary of the Dutch Society of Medical Ultrasound, and sits on the Technical Program Committee of the IEEE IUS and the Steering Committee of the IEEE MeMeA. He also serves as the Counselor of the IEEE Student Branch in Eindhoven. In addition, Prof. Mischi is associate editor and editorial board member of several journals, including IEEE T-UFFC, IEEE RBME, CMPB, IRBM, WFUMB Ultrasound Open, and Sensors.
Academic background
Massimo Mischi obtained his MSc in Electrical Engineering from La Sapienza University (Italy) in 1999. In 2004, he received his PhD from the Eindhoven University of Technology (TU/e). There, he became Assistant Professor in 2007, Associate Professor in 2011, and Full Professor in 2018.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
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Collaborations and top research areas from the last five years
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Personalized Response and Optimization for Medical Engineering Technology and Healthcare Evaluation and Understanding of Solutions
Johny, J. (Project member), Mischi, M. (Project Manager), Bergmans, J. W. M. (Project member), Mast, K. (Project member), Kuhn, J. (Project member) & Warmink, T. (Project member)
1/01/25 → 31/12/30
Project: Third tier
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Patient driven Research to Optimize TEchnologies for UsercenteredSolutions
Mischi, M. (Project Manager), de Vries, I. (Project member), Vacancy PHD (Project member) & van Loosdrecht, S. J. (Project member)
1/01/25 → 31/12/30
Project: Third tier
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Medical Innovation and Research Advancing Clinical Learning and Excellence HTSM/24.0173
Mischi, M. (Project Manager), Turco, S. (Project member), Lemmens, E. (Project member), Ramos Gonçalves Teresa Afonso, M. (Project member), Klein, G. (Project member), van Gisbergen, M. (Project member), Bhattacharya, A. (Project member), Kortman, M. (Project member), van Hoeven, M. (Project member), Jerry, E. (Project member), Messing, F. (Project member), Hof, D. (Project member), van Barschot, A. (Project member) & Barbagini, A. (Project member)
1/01/24 → 31/12/29
Project: Third tier
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Medical Innovation and New Technology
Mischi, M. (Project Manager), Vacancy PHD (Project member), Vacancy 12 (Project member), Paulussen, I. W. F. (Project member), Dekker, E. M. L. (Project member), van der Hout-van der Jagt, M. B. (Project member), Peters, K. (Project member), Bhattacharya, A. (Project member), van Herwijnen, A. (Project member), Vacancy Postdoc (Project member) & de Vries, I. (Project member)
1/01/24 → 31/12/29
Project: Third tier
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Patient-centered Exploration for Reliable, Smart and Efficient Utilization of healthcare Services
Mischi, M. (Project Manager), van Steenbergen, G. (Project member), Ramsaroep, A. (Project member), van der Pas, M. (Project member) & van Donkelaar, I. (Project member)
1/01/23 → 16/04/29
Project: Third tier
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Magnetic resonance dispersion imaging for localization of angiogenesis and cancer growth
Mischi, M., Turco, S., Lavini, C., Kompatsiari, K., Rosette, de la, J. J. M. C. H., Breeuwer, M. & Wijkstra, H., 2014, In: Investigative Radiology. 49, 8, p. 561-569Research output: Contribution to journal › Article › Academic › peer-review
31 Link opens in a new tab Citations (Scopus)8 Downloads (Pure) -
Ultrasound-contrast-agent dispersion and velocity imaging for prostate cancer localization
van Sloun, R. J. G., Demi, L., Postema, A., de la Rosette, J. J. M. C. H., Wijkstra, H. & Mischi, M., Jan 2017, In: Medical Image Analysis. 35, p. 610-619 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access49 Link opens in a new tab Citations (Scopus)3 Downloads (Pure) -
Towards dynamic contrast specific ultrasound tomography
Demi, L., Van Sloun, R. J. G., Wijkstra, H. & Mischi, M., 5 Oct 2016, In: Scientific Reports. 6, 8 p., 34458.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)361 Downloads (Pure) -
Multiparametric dynamic contrast-enhanced ultrasound imaging of prostate cancer
Wildeboer, R. R., Postema, A. W., Demi, L., Kuenen, M. P. J., Wijkstra, W. H. & Mischi, M. M., 1 Aug 2017, In: European Radiology. 27, 8, p. 3226-3234 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile48 Link opens in a new tab Citations (Scopus)346 Downloads (Pure) -
Dedicated entropy measures for early assessment of pregnancy progression from single-channel electrohysterography
Mischi, M., Chen, C., Ignatenko, T., de Lau, H., Ding, B., Oei, G. S. & Rabotti, C., Apr 2018, In: IEEE Transactions on Biomedical Engineering. 65, 4, p. 875-884 10 p.Research output: Contribution to journal › Article › Academic › peer-review
55 Link opens in a new tab Citations (Scopus)2 Downloads (Pure)
Datasets
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Simulated data from A Model-based Approach to Generating Annotated Pressure Support Waveforms
Waeijen-van Diepen, A. (Creator), Bakkes, T. H. G. F. (Creator), de Bie, A. (Creator), Turco, S. (Creator), Bouwman, R. A. (Creator), Woerlee, P. H. (Creator) & Mischi, M. (Creator), Eindhoven University of Technology, 31 Jan 2024
DOI: 10.4121/81220350-0f3d-4e0a-86cf-28c904a1cb09.v1, https://data.4tu.nl/datasets/81220350-0f3d-4e0a-86cf-28c904a1cb09 and 2 more links, https://data.4tu.nl/datasets/81220350-0f3d-4e0a-86cf-28c904a1cb09/1, https://data.4tu.nl/datasets/81220350-0f3d-4e0a-86cf-28c904a1cb09/2 (show fewer)
Dataset
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Experimental acoustic characterisation of an endoskeletal antibubble contrast agent: first results
Panfilova, A. (Contributor), Chen, P. (Contributor), van Sloun, R. J. G. (Contributor), Wijkstra, H. (Contributor), Postema, M. (Contributor), Poortinga, A. T. (Contributor) & Mischi, M. (Contributor), Zenodo, 17 Sept 2021
DOI: 10.5281/zenodo.5514221, https://zenodo.org/record/5514221
Dataset
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Models, datasets, and raw results of "Measurement of sweat gland activity by discrete sweat sensing, statistics, and deep learning"
Haakma, J. (Creator), Turco, S. (Creator), Peri, E. (Creator) & Mischi, M. (Creator), 4TU.Centre for Research Data, 27 Jun 2025
DOI: 10.4121/f62008b2-4c3a-42c6-bf3a-c55e37a9598c.v1
Dataset
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Constrained Cramér-Rao Bound of Multilinear Singular Value Decomposition
Calis, M. (Creator), Mischi, M. (Creator), van der Veen, A. J. (Contributor) & Rajan, R. T. (Creator), Code Ocean, 5 Aug 2024
DOI: 10.24433/co.6530222.v2, https://codeocean.com/capsule/6409749/tree/v2
Dataset
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Additional file 3: of Three-dimensional greyscale transrectal ultrasound-guidance and biopsy core preembedding for detection of prostate cancer: Dutch clinical cohort study
van der Aa, A. A. M. A. (Contributor), Mannaerts, C. K. (Creator), Gayet, M. C. W. (Creator), van der Linden, J. C. (Contributor), Schrier, B. P. (Creator), Sedelaar, J. P. M. (Contributor), Mischi, M. (Creator), Beerlage, H. P. (Creator) & Wijkstra, H. (Creator), Figshare, 16 Apr 2019
DOI: 10.6084/m9.figshare.8002820, https://springernature.figshare.com/articles/Additional_file_3_of_Three-dimensional_greyscale_transrectal_ultrasound-guidance_and_biopsy_core_preembedding_for_detection_of_prostate_cancer_Dutch_clinical_cohort_study/8002820 and one more link, https://springernature.figshare.com/articles/Additional_file_3_of_Three-dimensional_greyscale_transrectal_ultrasound-guidance_and_biopsy_core_preembedding_for_detection_of_prostate_cancer_Dutch_clinical_cohort_study/8002820/1 (show fewer)
Dataset
Prizes
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Prostate cancer localization by contrast-ultrasound angiogenesis imaging
Mischi, M. (Recipient), 2011
Prize: ERC › Starting › Scientific
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Novel cancer biomarkers by enhanced 3D convective-dispersion modeling of ultrasound-contrast-agent transport
Sivadas, A. (Speaker), Turco, S. (Speaker), Wijkstra, H. (Speaker), Beerlage, H. P. (Speaker) & Mischi, M. (Speaker)
7 Apr 2026Activity: Talk or presentation types › Contributed talk › Scientific
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Novel 3D convective-dispersion modeling of ultrasound-contrast-agent transport for imaging cancer angiogenesis
Sivadas, A. (Speaker), Turco, S. (Speaker), Wijkstra, H. (Speaker), Beerlage, H. P. (Speaker) & Mischi, M. (Speaker)
23 Jan 2026Activity: Talk or presentation types › Contributed talk › Scientific
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The generalized finite amplitude insert substitution method for estimation of the ultrasound parameter of nonlinearity
Panfilova, A. (Speaker), Chen, X. (Speaker), van Sloun, R. J. G. (Speaker), Wijkstra, H. (Speaker), Sapozhnikov, O. (Speaker) & Mischi, M. (Speaker)
8 Dec 2020Activity: Talk or presentation types › Contributed talk › Scientific
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On what dynamic contrast-enhanced ultrasound tells us about the underlying vascular architecture
Panfilova, A. (Speaker), Shelton, S. E. (Speaker), Caresio, C. (Speaker), van Sloun, R. J. G. (Speaker), Molinari, F. (Speaker), Wijkstra, H. (Speaker), Dayton, P. A. (Speaker) & Mischi, M. (Speaker)
18 Jan 2018Activity: Talk or presentation types › Plenary talk › Scientific
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27th Annual Advances in Contrast Ultrasound - ICUS Bubble Conference, Chicago (IL)
Mischi, M. (Speaker)
20 Sept 2012Activity: Talk or presentation types › Contributed talk › Scientific
Courses
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Medical ultrasound
Belt, H. J. W., Lopata, R. G. P., Mischi, M. & van Sloun, R. J. G. 1/09/13 → 31/08/26
Course
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Technology for care and cure
van der Hout-van der Jagt, M. B., Overeem, S., Klooster, D. C. W., van Gilst, M. M., Paulides, M. M., van Pul, C., Mischi, M., Vullings, R., Peri, E., Hurkmans, C., Sumser, K., Mestrom, R. M. C., Hommerson, S. & Turco, S. 1/09/24 → 31/08/26
Course
Press/Media
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New Prostate Cancer Data Has Been Reported by a Researcher at Eindhoven University of Technology (Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer)
Mischi, M., Wijkstra, H., Turco, S., Eduati, F. & Zwart, W. T.
27/06/23
1 item of Media coverage
Press/Media: Expert Comment
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Studies from University of Padua Have Provided New Information about Fetal Heart Rate (Automatic Optimization of Multichannel Electrode Configurations for Robust Fetal Heart Rate Detection By Blind Source Separation)
12/05/23
1 item of Media coverage
Press/Media: Expert Comment
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Eindhoven University of Technology Reports Findings in Networks (Shear-Wave Particle-Velocity Estimation and Enhancement Using a Multi-Resolution Convolutional Neural Network)
Chennakeshava, N., Chen, X., Mischi, M. & van Sloun, R. J. G.
4/05/23
1 item of Media coverage
Press/Media: Expert Comment
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Findings in the Area of Nanobubbles Reported from Eindhoven University of Technology (Pharmacokinetic Modeling of the Second-wave Phenomenon In Nanobubble-based Contrast-enhanced Ultrasound)
7/04/23
1 item of Media coverage
Press/Media: Expert Comment
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Ultrasound images of the heart with a small patch
7/02/23
2 items of Media coverage
Press/Media: Expert Comment