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Personal profile


“L’invenzione è l’attimo in cui con la tua conoscenza torni bambino – invention is a moment when with our knowledge we are children again.”

Research profile

Massimo Mischi is Full Professor in the Signal Processing Systems group at Eindhoven University of Technology (TU/e).

His research focuses on model-based quantitative analysis of biomedical signals, spanning from heart and muscle electrophysiology to ultrasound and MRI. His work is based on fundamental understanding and modeling of the full measurement chain, accounting for physiological sources, sensing physics, and noise sources and characterization. Main application domains are oncology, cardiovascular, gynecology-perinatology, sleep, and neuromuscular research, supported by a number of national and international grants in tight collaboration with clinical and industrial partners.

Mischi was awarded the STW VIDI Grant in 2009 and the ERC Starting Grant in 2011 for his research on contrast-enhanced ultrasound imaging of angiogenesis for cancer diagnostics. He successfully valorized his scientific results through >10 patent applications, 4 implementations in commercial software and setting up “HiPerMotion”, a hi-tech company for neuromuscular rehabilitation, based on two valorisation grants (Phase 1 and 2) awarded by the Dutch Foundation for Technology.

Mischi has (co)authored over 100 journal papers and 150 conference contributions. He serves as associate editor for the IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control and for the Journal BioMedical Engineering and Research (IRBM) published by Elsevier.

Academic background

Massimo Mischi obtained his MSc in Electrical Engineering from La Sapienza University (Italy) in 1999. In 2004, he received his PhD from the Eindhoven University of Technology (TU/e). There, he became Assistant Professor in 2007, Associate Professor in 2011, and Full Professor in 2018. In 2012, he founded the Biomedical Diagnostics (BM/d) research Laboratory, based on a team of over 25 researchers working in collaboration with key industrial and clinical partners.

Mischi is Senior Member of the IEEE, Chairman of the IEEE EMBS Benelux Chapter, Secretary of the Dutch Society of Medical Ultrasound (EFSUMB Section), and Board Member of the ESUI (Urological Imaging Section of the European Association of Urology).

Fingerprint Dive into the research topics where Massimo Mischi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Ultrasonography Medicine & Life Sciences
Ultrasonics Engineering & Materials Science
Electrocardiography Engineering & Materials Science
Contrast Media Medicine & Life Sciences
Prostate Medicine & Life Sciences
Imaging techniques Engineering & Materials Science
Monitoring Engineering & Materials Science

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2002 2020

22 Citations (Scopus)
8 Downloads (Pure)

Magnetic resonance dispersion imaging for localization of angiogenesis and cancer growth

Mischi, M., Turco, S., Lavini, C., Kompatsiari, K., Rosette, de la, J. J. M. C. H., Breeuwer, M. & Wijkstra, H., 2014, In : Investigative Radiology. 49, 8, p. 561-569

Research output: Contribution to journalArticleAcademicpeer-review

Magnetic Resonance Imaging
Capillary Permeability
21 Citations (Scopus)
1 Downloads (Pure)

Ultrasound-contrast-agent dispersion and velocity imaging for prostate cancer localization

van Sloun, R. J. G., Demi, L., Postema, A., de la Rosette, J. J. M. C. H. J., Wijkstra, H. & Mischi, M., Jan 2017, In : Medical Image Analysis. 35, Januari 2017, p. 610-619

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Contrast Media
Prostatic Neoplasms
Imaging techniques
2 Citations (Scopus)
200 Downloads (Pure)

Towards dynamic contrast specific ultrasound tomography

Demi, L., Van Sloun, R. J. G., Wijkstra, H. & Mischi, M., 5 Oct 2016, In : Scientific Reports. 6, 8 p., 34458.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Contrast Media
Breast Neoplasms
17 Citations (Scopus)
71 Downloads (Pure)

Multiparametric dynamic contrast-enhanced ultrasound imaging of prostate cancer

Wildeboer, R. R., Postema, A. W., Demi, L., Kuenen, M. P. J., Wijkstra, W. H. & Mischi, M. M., 1 Aug 2017, In : European Radiology. 27, 8, p. 3226-3234 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Prostatic Neoplasms
7 Citations (Scopus)
1 Downloads (Pure)

Dedicated entropy measures for early assessment of pregnancy progression from single-channel electrohysterography

Mischi, M., Chen, C., Ignatenko, T., de Lau, H., Ding, B., Oei, G. S. & Rabotti, C., 2018, In : IEEE Transactions on Biomedical Engineering. 65, 4, p. 875-881

Research output: Contribution to journalArticleAcademicpeer-review

Risk assessment


Prostate cancer localization by contrast-ultrasound angiogenesis imaging

M. Mischi (Recipient), 2011

Prize: ERCStartingScientific

Prostatic Neoplasms
Spatio-Temporal Analysis

Activities 2002 2012

  • 13 Contributed talk

27th Annual Advances in Contrast Ultrasound - ICUS Bubble Conference, Chicago (IL)

Massimo Mischi (Speaker)
20 Sep 2012

Activity: Talk or presentation typesContributed talkScientific

Voorjaarsvergadering van de Nederlandse Vereniging voor Urologie (NVU), 10-11 mei 2012, 's-Hertogenbosch, Nederland

Massimo Mischi (Speaker)
10 May 2012

Activity: Talk or presentation typesContributed talkScientific

Health Valley 2012, Nijmegen, The Netherlands

Massimo Mischi (Speaker)
15 Mar 2012

Activity: Talk or presentation typesContributed talkScientific


Biomedical sensing technology

1/09/15 → …


Medical ultrasound

1/09/13 → …


Student theses

2D vascular strain imaging, using plane wave ultrasound

Author: Wijnhoven, L., 30 Apr 2012

Supervisor: Mischi, M. (Supervisor 1), Hansen, H. (External coach) & de Korte, C. (External coach)

Student thesis: Master

Acoustic and cardiovascular quantification by transesophageal echography and Luminity(R) contrast agent dilution

Author: Hermens, B., 31 Oct 2007

Supervisor: Mischi, M. (Supervisor 1)

Student thesis: Master


Analysis of nonlinear features from electrohysterogram

Author: Chen, C., 31 Oct 2015

Supervisor: Mischi, M. (Supervisor 1) & Rabotti, C. (Supervisor 2)

Student thesis: Master

Analysis of the uterine electrical activity ex-vivo based on electrohysterography (EHG)

Author: Ye, X., 26 Apr 2018

Supervisor: Rabotti, C. (Supervisor 1), Mischi, M. (Supervisor 2) & Schoot, B. (Supervisor 2)

Student thesis: Master

An elastic registration method for validation of prostate cancer ultrasound imaging

Author: Schalk, S., 31 Aug 2011

Supervisor: Mischi, M. (Supervisor 1) & Wijkstra, H. (Supervisor 2)

Student thesis: Master