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Personal profile


“L’invenzione è l’attimo in cui con la tua conoscenza torni bambino – invention is a moment when with our knowledge we are children again.”

Research profile

Massimo Mischi is Full Professor in the Signal Processing Systems group at Eindhoven University of Technology (TU/e).

His research focuses on model-based quantitative analysis of biomedical signals, spanning from heart and muscle electrophysiology to ultrasound and MRI. His work is based on fundamental understanding and modeling of the full measurement chain, accounting for physiological sources, sensing physics, and noise sources and characterization. Main application domains are oncology, cardiovascular, gynecology-perinatology, sleep, and neuromuscular research, supported by a number of national and international grants in tight collaboration with clinical and industrial partners.

Mischi was awarded the STW VIDI Grant in 2009 and the ERC Starting Grant in 2011 for his research on contrast-enhanced ultrasound imaging of angiogenesis for cancer diagnostics. He successfully valorized his scientific results through >10 patent applications, 4 implementations in commercial software and setting up “HiPerMotion”, a hi-tech company for neuromuscular rehabilitation, based on two valorisation grants (Phase 1 and 2) awarded by the Dutch Foundation for Technology.

Mischi has (co)authored over 100 journal papers and 150 conference contributions. He serves as associate editor for the IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control and for the Journal BioMedical Engineering and Research (IRBM) published by Elsevier.

Academic background

Massimo Mischi obtained his MSc in Electrical Engineering from La Sapienza University (Italy) in 1999. In 2004, he received his PhD from the Eindhoven University of Technology (TU/e). There, he became Assistant Professor in 2007, Associate Professor in 2011, and Full Professor in 2018. In 2012, he founded the Biomedical Diagnostics (BM/d) research Laboratory, based on a team of over 25 researchers working in collaboration with key industrial and clinical partners.

Mischi is Senior Member of the IEEE, Chairman of the IEEE EMBS Benelux Chapter, Secretary of the Dutch Society of Medical Ultrasound (EFSUMB Section), and Board Member of the ESUI (Urological Imaging Section of the European Association of Urology).

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Research Output

Magnetic resonance dispersion imaging for localization of angiogenesis and cancer growth

Mischi, M., Turco, S., Lavini, C., Kompatsiari, K., Rosette, de la, J. J. M. C. H., Breeuwer, M. & Wijkstra, H., 2014, In : Investigative Radiology. 49, 8, p. 561-569

Research output: Contribution to journalArticleAcademicpeer-review

  • 23 Citations (Scopus)
    8 Downloads (Pure)

    Ultrasound-contrast-agent dispersion and velocity imaging for prostate cancer localization

    van Sloun, R. J. G., Demi, L., Postema, A., de la Rosette, J. J. M. C. H. J., Wijkstra, H. & Mischi, M., Jan 2017, In : Medical Image Analysis. 35, Januari 2017, p. 610-619

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 28 Citations (Scopus)
    1 Downloads (Pure)

    Towards dynamic contrast specific ultrasound tomography

    Demi, L., Van Sloun, R. J. G., Wijkstra, H. & Mischi, M., 5 Oct 2016, In : Scientific Reports. 6, 8 p., 34458.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 2 Citations (Scopus)
    203 Downloads (Pure)

    Multiparametric dynamic contrast-enhanced ultrasound imaging of prostate cancer

    Wildeboer, R. R., Postema, A. W., Demi, L., Kuenen, M. P. J., Wijkstra, W. H. & Mischi, M. M., 1 Aug 2017, In : European Radiology. 27, 8, p. 3226-3234 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 21 Citations (Scopus)
    74 Downloads (Pure)

    Dedicated entropy measures for early assessment of pregnancy progression from single-channel electrohysterography

    Mischi, M., Chen, C., Ignatenko, T., de Lau, H., Ding, B., Oei, G. S. & Rabotti, C., Apr 2018, In : IEEE Transactions on Biomedical Engineering. 65, 4, p. 875-884 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 10 Citations (Scopus)
    1 Downloads (Pure)


    Prostate cancer localization by contrast-ultrasound angiogenesis imaging

    M. Mischi (Recipient), 2011

    Prize: ERCStartingScientific

  • Activities

    • 13 Contributed talk

    27th Annual Advances in Contrast Ultrasound - ICUS Bubble Conference, Chicago (IL)

    Massimo Mischi (Speaker)
    20 Sep 2012

    Activity: Talk or presentation typesContributed talkScientific

    Voorjaarsvergadering van de Nederlandse Vereniging voor Urologie (NVU), 10-11 mei 2012, 's-Hertogenbosch, Nederland

    Massimo Mischi (Speaker)
    10 May 2012

    Activity: Talk or presentation typesContributed talkScientific

    Health Valley 2012, Nijmegen, The Netherlands

    Massimo Mischi (Speaker)
    15 Mar 2012

    Activity: Talk or presentation typesContributed talkScientific


    Biomedical sensing technology

    1/09/15 → …


    Medical ultrasound

    1/09/13 → …


    Student theses

    2D vascular strain imaging, using plane wave ultrasound

    Author: Wijnhoven, L., 30 Apr 2012

    Supervisor: Mischi, M. (Supervisor 1), Hansen, H. (External coach) & de Korte, C. (External coach)

    Student thesis: Master

    Acoustic and cardiovascular quantification by transesophageal echography and Luminity(R) contrast agent dilution

    Author: Hermens, B., 31 Oct 2007

    Supervisor: Mischi, M. (Supervisor 1)

    Student thesis: Master


    Analysis of nonlinear features from electrohysterogram

    Author: Chen, C., 31 Oct 2015

    Supervisor: Mischi, M. (Supervisor 1) & Rabotti, C. (Supervisor 2)

    Student thesis: Master

    Analysis of the uterine electrical activity ex-vivo based on electrohysterography (EHG)

    Author: Ye, X., 26 Apr 2018

    Supervisor: Rabotti, C. (Supervisor 1), Mischi, M. (Supervisor 2) & Schoot, B. (Supervisor 2)

    Student thesis: Master

    An elastic registration method for validation of prostate cancer ultrasound imaging

    Author: Schalk, S., 31 Aug 2011

    Supervisor: Mischi, M. (Supervisor 1) & Wijkstra, H. (Supervisor 2)

    Student thesis: Master