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Personal profile

Quote

I use big microscopes to look at small objects.

Research profile

Lorenzo Albertazzi is an associate professor at the TU/e department of Biomedical Engineering (research group Molecular Biosensing for Medical Diagnostics). He is also junior group leader at the Institute of Bioengineering of Catalonia (IBEC) in Barcelona, where he leads the 'Nanoscopy for Nanomedicine' group. For most of his career he has been jumping between Chemistry and Biophysics; in his research he now aims to combine both to achieve a molecular understanding of synthetic materials in the biological environment, using optical microscopy and nanoscopy.

With his 2017 ERC Starting Grant, Lorenzo aims at the 'Design of Nanomaterials for Targeted Therapies Guided by Super Resolution Imaging'. In the NANOSTORM project he plans to use super resolution microscopy to examine nanomaterials that have potential as cancer therapies, and understand their interactions with their target: the diseased cells. Doing so will help identify the key principles that are needed to rationally design the next generation of targeted, super-efficient cancer treatments

Academic background

Lorenzo Albertazzi obtained a MSc in Chemistry (2007) and a PhD in Biophysics (2011) from Scuola Normale Superiore (Pisa, Italy). He then joined Eindhoven University of Technology (TU/e, The Netherlands) as postdoctoral researcher. In 2013, he was awarded a fellowship of the Institute for Complex Molecular Systems (ICMS) at TU/e, and in 2014 he became a NWO/VENI fellow (2014). In 2015, he moved to Barcelona (Spain) to the Institute of Bioengineering of Catalonia (IBEC) to start the 'Nanoscopy for Nanomedicine' group that he currently leads. In 2017, he received an ERC starting grant and in 2018 he was appointed Associate Professor at the TU/e department of Biomedical Engineering, with the research group Molecular Biosensing.

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Research Output

  • 2585 Citations
  • 63 Article
  • 3 Review article
  • 1 Poster

Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: boosting the efficacy of intravenously administered therapeutic adenoviruses

Brugada-Vilà, P., Cascante, A., Lázaro, M. Á., Castells-Sala, C., Fornaguera, C., Rovira-Rigau, M., Albertazzi, L., Borros, S. & Fillat, C., 1 Jan 2020, In : Theranostics. 10, 6, p. 2744-2758 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
  • 18 Downloads (Pure)

    Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment

    De Coen, R., Nuhn, L., Perera, C., Arista-Romero, M., Risseeuw, M. D. P., Freyn, A., Nachbagauer, R., Albertazzi, L., Van Calenbergh, S., Spiegel, D. A., Peterson, B. R. & De Geest, B. G., 10 Feb 2020, In : Biomacromolecules. 21, 2, p. 793-802 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • A stochastic view on surface inhomogeneity of nanoparticles

    Post, R. A. J., van der Zwaag, D., Bet, G., Wijnands, S. P. W., Albertazzi, L., Meijer, E. W. & van der Hofstad, R. W., 10 Apr 2019, In : Nature Communications. 10, 1, 11 p., 1663.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • 5 Citations (Scopus)
    47 Downloads (Pure)

    Efficient small-scale conjugation of DNA to primary antibodies for multiplexed cellular targeting

    Cremers, G., Rosier, B., Riera Brillas, R., Albertazzi, L. & de Greef, T., 18 Sep 2019, In : Bioconjugate Chemistry. 30, 9, p. 2384-2392 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • 2 Citations (Scopus)
    25 Downloads (Pure)

    Quantifying guest–host dynamics in supramolecular assemblies to analyze their robustness

    Bastings, M. M. C., Hermans, T. M., Spiering, A. J. H., Kemps, E. W. L., Albertazzi, L., Kurisinkal, E. E. & Dankers, P. Y. W., 1 Jan 2019, In : Macromolecular Bioscience. 19, 1, 11 p., 1800296.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 2 Citations (Scopus)
    2 Downloads (Pure)

    Prizes

  • Personalized attack on cancer cells

    Lorenzo Albertazzi (Recipient), 2019

    Prize: NWOVidiScientific

  • Courses

    DBL Entering the lab

    1/09/13 → …

    Course

    DBL Entering the lab

    1/09/13 → …

    Course

    Student theses

    Binding a BTA fiber to dsDNA via intercalation

    Author: Visser, P., 31 Aug 2015

    Supervisor: Baker, M. (Supervisor 1), Albertazzi, L. (Supervisor 2) & Meijer, E. (Supervisor 2)

    Student thesis: Master

    File

    Crosslinking supramolecular polymers : gaining control over dynamics

    Author: Hoogland, D., 31 Aug 2014

    Supervisor: Albertazzi, L. (Supervisor 1) & Meijer, E. (Supervisor 2)

    Student thesis: Master

    Enzyme-responsive supramolecular polymers

    Author: van der Veeken, N., 31 Jan 2015

    Supervisor: Albertazzi, L. (Supervisor 1), Meijer, E. (Supervisor 2), de Greef, T. (Supervisor 2) & Merkx, M. (Supervisor 2)

    Student thesis: Master

    Exploring multistep non-covalent synthesis: investigating supramolecular host-guest assemblies

    Author: Goor, O., 31 May 2013

    Supervisor: Bastings, M. (Supervisor 1), Albertazzi, L. (Supervisor 2) & Dankers, P. (Supervisor 2)

    Student thesis: Master