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Personal profile


“My ambition is to engineer functional nanosystems to mimic the structural and systematic complexity of biology”

Research profile

Loai Abdelmohsen's research experience is in the field of polymer synthesis, nanoparticles characterization, copolymer self-assembly and shape transformations, and the design of nanomotors. He is a member of the Bio-organic chemistry research group at Eindhoven University of Technology where the objective is to construct smart compartments with life-like features along two main lines of research: nanomedicine and artificial cells and organelles.

Academic background

Loai Abdelmohsen studied chemistry at Alexandria University (Egypt) where he received his bachelor degree in 2008. He then undertook a research programme in the field of electrochemistry at Monash University (Australia). In 2013 he started his masters in chemistry at Radboud University, which he completed in 2013. He continued with PhD research at the Bio-Organic Chemistry group at Radboud University where he obtained his PhD in 2017 with his thesis 'Polymeric Assemblies with Controlled Shape and Function' under supervision of professors Daniela Wilson and Jan van Hest. Abdelmohsen currently is assistant professor at the Bio-Organic Chemistry group at Eindhoven University of Technology.

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Research Output 2014 2018

  • 379 Citations
  • 16 Article
  • 1 Meeting Abstract
  • 1 Review article
  • 1 Phd Thesis 4 Research NOT TU/e / Graduation NOT TU/e)

Adaptive polymersome and micelle morphologies in anticancer nanomedicine: from design rationale to fabrication and proof-of-concept studies

Pijpers, I. A. B., Abdelmohsen, L. K. E. A., Xia, Y., Cao, S., Williams, D. S., Meng, F., van Hest, J. C. M. & Zhong, Z., 4 Sep 2018, In : Advanced Therapeutics. 1800068

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Medical nanotechnology
Drug delivery

A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

De Jong, E., Williams, D. S., Abdelmohsen, L. K. E. A., van Hest, J. C. M. & Zuhorn, I. S., 10 Nov 2018, In : Journal of Controlled Release. 289, p. 14-22 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Fluorescence Spectrometry
Blood-Brain Barrier
2 Citations

Biodegradable synthetic organelles demonstrate ROS shielding in human-complex-I-deficient fibroblasts

van Oppen, L. M. P. E., Abdelmohsen, L. K. E. A., van Emst-de Vries, S. E., Welzen, P. L. W., Wilson, D. A., Smeitink, J. A. M., Koopman, W. J. H., Brock, R., Willems, P. H. G. M., Williams, D. S. & van Hest, J. C. M., 25 Jul 2018, In : ACS Central Science. 4, 7, p. 917-928 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Polyethylene glycols
Open Access
Medical nanotechnology
Polyethylene glycols
Particle interactions


Student theses

Development of reduction responsive polymersomes for controlled drug delivery

Author: Stam, R., 13 Nov 2018

Supervisor: Pijpers, I. (Supervisor 1), van Hest, J. (Supervisor 2), Brunsveld, L. (Supervisor 2) & Abdelmohsen, L. (Supervisor 2)

Student thesis: Master