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Personal profile


Chemical systems exhibit behavior rich enough to provide endless research questions in dynamics and control. Understanding and expressing them mathematically is the cornerstone of my research. The rest is icing on the cake. 

Research profile

Leyla Özkan is an Assistant Professor in the Electrical Engineering Department at Eindhoven University of Technology (TU/e). Her research seeks to improve the operation and increase the understanding of industrial chemical systems. She uses modeling, system theory and mathematics to develop new tools and methods and apply them to chemical applications. She collaborates closely with industrial partners, developing solutions for processes with real industrial needs, and her work has demonstrated the commercial value of these methods. The group specifically advances methods for autonomous operation support technology: models for predictive control, real-time optimization, process monitoring both at unit and enterprise level, and integration of process design with instrumentation and operational aspects.  

In addition, Özkan teaches master’s degree level courses such as Model Based Control, Advanced Process Control and the System Integration Project in the Systems and Control master’s degree program. She is the chair of the PSE-NL Network and is an associate editor for the Journal of Process Control. 

Academic background

Leyla Özkan holds a BSc and MSc in Chemical Engineering from Bogazici University (Turkey). She undertook her PhD in Chemical Engineering at Lehigh University (USA), studying model-based control of chemical processes.  

Upon graduatingÖzkan became a postdoc at the University of Newcastle-upon-Tyne (UK) as part of EPSRC project Chemicals Behaving Badly II. In this projectÖzkan developed tools and methods for the control of pharmaceutical crystallization processes for companies including GSK, Pfizer, Syngenta and Astrazeneca 

In 2005, Özkan joined IPCOS Technology Boxtel as an R&D consultant, developing model reduction technology for glass melting tanks. In 2009, she returned to academia as Assistant Professor in the Control Systems group of the Electrical Engineering department at Eindhoven University of Technology (TU/e). 

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Research Output

Open Access
  • 7 Downloads (Pure)

    A second order cone formulation of min-max MPC with zone control for LPV systems

    Marquez-Ruiz, A., Patino, J., Ozkan, L. & Espinosa, J., Oct 2019, 4th IEEE Colombian Conference on Automatic Control: Automatic Control as Key Support of Industrial Productivity, CCAC 2019 - Proceedings. Garcia-Tirado, J., Munoz-Durango, D., Alvarez, H. & Botero-Castro, H. (eds.). Piscataway: Institute of Electrical and Electronics Engineers, 6 p. 8921029

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

  • Dynamic modeling of milk acidification for product design and process control

    Porru, M., Ozkan, L., Huppertz, T. & Szymanska, E., 9 Oct 2019.

    Research output: Contribution to conferencePoster

    Integration of Max-plus-linear scheduling and control

    Dirza, R., Marquez Ruiz, A., Ozkan, L. & Mendez Blanco, C., 25 Jul 2019, In : Computer Aided Chemical Engineering. 46, p. 1279-1284 6 p.

    Research output: Contribution to journalConference articleAcademicpeer-review

  • 2 Downloads (Pure)

    Modeling of reactive batch distillation processes for control

    Marquez Ruiz, A., Mendez Blanco, C. S. & Ozkan, L., 2 Feb 2019, In : Computers and Chemical Engineering. 121, p. 86-98 13 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 5 Citations (Scopus)
    1 Downloads (Pure)


    29th European Symposium on Computer Aided Process Engineering (ESCAPE 29)

    Leyla Özkan (Organiser)
    Aug 2018Jul 2019

    Activity: Participating in or organising an event typesConferenceScientific


    Advanced process control

    1/09/15 → …


    Model-based control

    1/09/15 → …


    Process dynamics and control

    1/09/13 → …


    Press / Media

    Simulation Models Increase Process Efficiency

    Leyla Özkan


    1 Media contribution

    Press/Media: Research

    Dynamic modeling of ultrafiltration membranes for whey separation processes

    Leyla Özkan


    1 item of Media coverage

    Press/Media: Expert Comment

    Student theses

    Disturbance model and observer tuning method for model predictive control

    Author: Gonzalez Burgos, J., 30 Sep 2011

    Supervisor: Backx, A. (Supervisor 1) & Ozkan, L. (Supervisor 2)

    Student thesis: Master

    Extremum seeking based auto-tuning of MPC for a tubular polymerization reactor

    Author: Bruggeman, O., 31 Aug 2015

    Supervisor: Ozkan, L. (Supervisor 1)

    Student thesis: Master

    LPV modelling and parameter estimation for reaction systems

    Author: Prikken, D., 7 Sep 2018

    Supervisor: Ozkan, L. (Supervisor 1), Mendez Blanco, C. (Supervisor 2) & Van den Hof, P. (Supervisor 2)

    Student thesis: Master

    Modeling and optimal control of fluidized bed membrane reactors

    Author: Wu, J., 27 Jun 2018

    Supervisor: Özkan, L. (Supervisor 1) & van Sint Annaland, M. (Supervisor 2)

    Student thesis: Master

    Model learning predictive control with applications to batch processes

    Author: Loonen, M., 28 Jun 2018

    Supervisor: Weiland, S. (Supervisor 1), Ozkan, L. (Supervisor 2), Marquez Ruiz, A. (Supervisor 2) & Saltik, M. (Supervisor 2)

    Student thesis: Master