• 3120 Citations
1986 …2019
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Research Output 1986 2019

2019
12 Downloads (Pure)

Conformation switching of single native proteins revealed by nanomechanical probing without a pulling force

Gutierrez Mejia, F. A., Moerland, C., van Ijzendoorn, L. & Prins, M., 14 Nov 2019, In : Nanoscale. 11, 42, p. 19933-19942 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Conformations
Proteins
Calcium
Antibodies
Troponin
1 Citation (Scopus)
13 Downloads (Pure)

Rate of dimer formation in stable colloidal solutions quantified using an attractive interparticle force

Scheepers, M. R. W., Romijn, A. R., van Ijzendoorn, L. J. & Prins, M. W. J., 13 Aug 2019, In : Langmuir. 35, 32, p. 10533-10541 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Dimers
dimers
Agglomeration
Chemical reactivity
Particle interactions
6 Citations (Scopus)
28 Downloads (Pure)

Rotating magnetic particles for lab-on-chip applications-a comprehensive review

Moerland, C. P., van IJzendoorn, L. J. & Prins, M. W. J., 21 Mar 2019, In : Lab on a Chip. 19, 6, p. 919-933 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Magnetic Fields
Magnetic fields
Torque
Molecules
Biomolecules
7 Downloads (Pure)

Single-dimer formation rate reveals heterogeneous particle surface reactivity

Scheepers, M. R. W., van IJzendoorn, L. J. & Prins, M. W. J., 13 Oct 2019, In : Langmuir. 35, 44, p. 14272-14281 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Dimers
Agglomeration
reactivity
dimers
Antibodies
2018
9 Citations (Scopus)
72 Downloads (Pure)

Continuous biomarker monitoring by particle mobility sensing with single molecule resolution

Visser, E. W. A., Yan, J., van IJzendoorn, L. J. & Prins, M. W. J., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 2541.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
biomarkers
Biomarkers
Technology
Molecules
Monitoring
3 Citations (Scopus)
149 Downloads (Pure)

Nanoscale interparticle distance within dimers in solution measured by light scattering

van Vliembergen, R. W. L., van Ijzendoorn, L. J. & Prins, M. W. J., 9 Jan 2018, In : Langmuir. 34, 1, p. 179-186 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Colloids
Ionic strength
Dimers
Light scattering
Large scale systems
2017
5 Citations (Scopus)

Optimization and characterization of a flow cell for heat-transfer-based biosensing

Stilman, W., Jooken, S., Wackers, G., Cornelis, P., Khorshid, M., Yongabi, D., Akkermans, O., Dyson, S., van Grinsven, B., Cleij, T., van IJzendoorn, L., Wagner, P. & Eersels, K., 1 Sep 2017, In : Physica Status Solidi A : Applications and material science. 214, 9, 9 p., 1600758.

Research output: Contribution to journalArticleAcademicpeer-review

heat transfer
Heat transfer
heat transmission
optimization
cells
2016
5 Citations (Scopus)
201 Downloads (Pure)

Distance within colloidal dimers probed by rotation-induced oscillations of scattered light

van Vliembergen, R. W. L., van IJzendoorn, L. J. & Prins, M. W. J., 25 Jan 2016, In : Optics Express. 24, 2, p. A123-A138

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
dimers
oscillations
scattering cross sections
simulation
Mie scattering
1 Citation (Scopus)
3 Downloads (Pure)

Evanescent field biosensor using polymer slab waveguide-based cartridges for the optical detection of nanoparticles

Teigell Beneitez, N., Missinne, J., Visser, E. W. A., Van Ijzendoorn, L. J., Prins, M. W. J., Schleipen, J. J. H. B., Vinkenborg, J. L., Rietjens, G., Verschuuren, M. A., Krishnamoorthy, G., Orsel, J. G. & Van Steenberge, G., 1 May 2016, In : IEEE Journal of Selected Topics in Quantum Electronics. 22, 3, p. 1-8

Research output: Contribution to journalArticleAcademicpeer-review

Evanescent fields
cartridges
bioinstrumentation
Biosensors
slabs
13 Citations (Scopus)
7 Downloads (Pure)

Particle motion analysis reveals nanoscale bond characteristics and enhances dynamic range for biosensing

Visser, E. W. A., van IJzendoorn, L. J. & Prins, M. W. J., 22 Mar 2016, In : ACS Nano. 10, 3, p. 3093-3101 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

particle motion
dynamic range
Substrates
Assays
Molecules
2015
2 Citations (Scopus)
2 Downloads (Pure)

Ara h 1 protein–antibody dissociation study : evidence for binding inhomogeneities on a molecular scale

Perez-Ruiz, E., Spasic, D., Gils, A., IJzendoorn, van, L. J., Prins, M. W. J. & Lammertyn, J., 2015, In : New Biotechnology. 32, 5, p. 458-466 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Proteins
Molecular Conformation
Polystyrenes
Antibodies
Normal Distribution

Editorial

van IJzendoorn, L. J., 5 Sep 2015, In : New Biotechnology. 32, 5, p. 419 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)
4 Downloads (Pure)

Effective particle magnetic moment of multi-core particles

Ahrentorp, F., Astalan, A., Blomgren, J., Jonasson, C., Wetterskog, E., Svedlindh, P., Lak, A., Ludwig, F., Van IJzendoorn, L. J., Westphal, F., Grüttner, C., Gehrke, N., Gustafsson, S., Olsson, E. & Johansson, C., 15 Apr 2015, In : Journal of Magnetism and Magnetic Materials. 380, p. 221-226 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Magnetic moments
magnetic moments
Transmission electron microscopy
Dynamic light scattering
Light transmission
1 Citation (Scopus)
2 Downloads (Pure)

Molecular interference in antibody–antigen interaction studied with magnetic force immunoassay

Dorokhin, D. V., IJzendoorn, van, L. J., Jong, de, A. M., Nieto, L., Brunsveld, L., Orsel, J. G. & Prins, M. W. J., 2015, In : New Biotechnology. 32, 5, p. 450-457 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immunoassay
Surface-Active Agents
Troponin
Surface active agents
Antigens
3 Citations (Scopus)
8 Downloads (Pure)

Surfactants modify the torsion properties of proteins : a single molecule study

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2015, In : New Biotechnology. 32, 5, p. 441-449 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Surface-Active Agents
Torsional stress
Surface active agents
Proteins
Polysorbates
2014
1 Downloads (Pure)

Altering the torsional rigidity of proteins with surfactants

Gutierrez Mejia, F. A., Reenen, van, A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014, 9th EBSA European Biophysics Congress, 13-17 July 2013, Lisbon, Portugal. Berlin: Springer, p. 170 O-518. (European Biophysics Journal; vol. 42, no. suppl. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

surfactants
proteins

Altering the torsional rigidity of proteins with surfactants

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014, Proceedings of the first European Conference on Novel Technologies for In Vitro Diagnostics, (DIATECH), 6-8 October 2014, Leuven, Belgium.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Surface-Active Agents
Rigidity
Proteins
Torsional stress
Polysorbates
34 Downloads (Pure)

A rotating molecular ruler : determining nanometer-scale particle-particle distances in an optomagnetic cluster assay

Vliembergen, van, R. W. L., IJzendoorn, van, L. J. & Prins, M. W. J., 2014, Poster presented at the 10th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, 10-14 June 2014, Dresden, Germany. p. 169-169

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
File
biomarkers
light scattering
antibodies
scattering cross sections
molecules
1 Downloads (Pure)

A short dsDNA model system for torsional deformation studies with magnetic tweezers

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014.

Research output: Contribution to conferencePoster

A short dsDNA model system for torsional deformation studies with magnetic tweezers

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014.

Research output: Contribution to conferencePoster

Characterization of individual superparamagnetic particles using a torsional molecular spring

Gutierrez Mejia, F. A., Reenen, van, A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014.

Research output: Contribution to conferencePoster

biomarkers
light scattering
antibodies
scattering cross sections
molecules
biomarkers
light scattering
antibodies
scattering cross sections
molecules

Model assays to vary particle-particle distances in an optomagnetic cluster assay

Vliembergen, van, R. W. L., IJzendoorn, van, L. J. & Prins, M. W. J., 2014.

Research output: Contribution to conferencePoster

biomarkers
biotin
covalent bonds
Mie scattering
classifying

Motion patterns of tethered particles reveal heterogeneities on a molecular scale

Visser, E. W. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014, NanoCity 2014, 27-28 October 2014, Utrecht, The Netherlands.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Motion patterns of tethered particles reveal heterogeneities on a molecular scale

Visser, E. W. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014, Proceedings of the First European Conference on Novel Technologies for In Vitro Diagnostics, (DIATECH), 6-8 October 2014, Leuven, Belgium.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Motion patterns of tethered particles reveal heterogeneities on a molecular scale

Visser, E. W. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2014, Dutch Physics Conference, Physics@FOM, 21-22 January 2014, Veldhoven, The Netherlands.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

particle motion
antibodies
molecules
deoxyribonucleic acid
chips

On the origin of torque generation in superparamagnetic particles

Moerland, C. P., Prins, M. W. J. & IJzendoorn, van, L. J., 2014.

Research output: Contribution to conferencePoster

torque
magnetization
torsion
time lag
angular distribution
24 Downloads (Pure)

On torque generation in superparamagnetic particles

Moerland, C. P., Prins, M. W. J. & IJzendoorn, van, L. J., 2014.

Research output: Contribution to conferencePoster

Open Access
File
10 Citations (Scopus)
117 Downloads (Pure)

Probing the force-induced dissociation of aptamer-protein complexes

Perez-Ruiz, E., Kemper, M., Spasic, D., Gils, A., IJzendoorn, van, L. J., Lammertyn, J. & Prins, M. W. J., 2014, In : Analytical Chemistry. 86, 6, p. 3084-3091

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Proteins
Energy barriers
Fiber optics
Rate constants
Kinetics

Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing

Visser, E. W. A., IJzendoorn, van, L. J. & Prins, M. W. J., 1 Jan 2014, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 2303-2305 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Lab-on-a-chip
Optical systems
Sensors
2013

Altering the torsional rigidity of proteins by surfactants

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, Proceedings of the Satellite Symposium on Bionanotechnology : Recent Advances, 10-13 July 2013, Sesimbra, Portugal. Sesimbra, Portugal

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Altering the torsional rigidity of proteins by surfactants

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, Proceedings of the Dutch Meeting on Molecular and Cellular Biophysics 2013, 30 September - 1 October 2013, Veldhoven, The Netherlands. Veldhoven, The Netherlands

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

28 Downloads (Pure)

Altering the torsional rigidity of proteins by surfactants

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, MicroNanoConference ‘13, 11-12 December 2013, Ede, The Netherlands. p. 1-30

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
File

Altering the torsional rigidity of proteins with surfactants

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, 9th European Biophysics Congress (EBSA), Lisbon, 13-17 2013.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

biomarkers
light scattering
antibodies
scattering cross sections
molecules
biomarkers
light scattering
antibodies
scattering cross sections
molecules
5 Citations (Scopus)
81 Downloads (Pure)

Diffusion enhancement in on/off ratchets

Germs, W. C., Roeling, E. M., IJzendoorn, van, L. J., Janssen, R. A. J. & Kemerink, M., 2013, In : Applied Physics Letters. 102, 7, p. 073104-1/5 5 p., 073104.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
augmentation
curves
polystyrene
asymmetry
scaling

Effect of surfactants on the torsion properties of individual protein complexes

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013.

Research output: Contribution to conferencePoster

proteins
polymers
interactions
energy
dissociation

Optomagnetic detection technology reveals nanoparticle cluster geometries in biomarker assays

Vliembergen, van, R. W. L., Saha, B., Ranzoni, A., Schleipen, J., IJzendoorn, van, L. J. & Prins, M. W. J., 2013.

Research output: Contribution to conferencePoster

biomarkers
nanoparticles
geometry
magnetic fields
antibodies

Study of the mechanical properties of antigen-antibody systems with magnetic beads and applications in biosensors

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, Proceedings of the BIOMAX Sysmposium, Uppsala, Sweden. Uppsala, Sweden

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Study of the torsional properties protein complexes

Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, Biomax Symposium. Lausanne, Switzerland

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

14 Citations (Scopus)
3 Downloads (Pure)

Torsion profiling of proteins using magnetic particles

Reenen, van, A., Gutierrez Mejia, F. A., IJzendoorn, van, L. J. & Prins, M. W. J., 2013, In : Biophysical Journal. 104, 5, p. 1073-1080

Research output: Contribution to journalArticleAcademicpeer-review

Immunoglobulin G
Torque
Proteins
Research