• 2037 Citations
20102020

Research output per year

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Research Output

  • 2037 Citations
  • 48 Article
  • 2 Review article
  • 1 Phd Thesis 4 Research NOT TU/e / Graduation NOT TU/e)
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Article
2020

Programmable bivalent peptide-DNA locks for pH-based control of antibody activity

Engelen, W., Zhu, K., Subedi, N., Idili, A., Ricci, F., Tel, J. & Merkx, M., 22 Jan 2020, In : ACS Central Science. 6, 1, p. 22-31 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
20 Downloads (Pure)
2019

A pipette-tip based method for seeding cells to droplet microfluidic platforms

Sinha, N., Subedi, N., Wimmers, F., Soennichsen, M. & Tel, J., 11 Feb 2019, In : Journal of Visualized Experiments (JoVE). 144, 10 p., e57848.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
45 Downloads (Pure)

Development of morphologically discrete PEG-PDLLA nanotubes for precision nanomedicine

Wauters, A. C., Pijpers, I. A. B., Mason, A. F., Williams, D. S., Tel, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 14 Jan 2019, In : Biomacromolecules. 20, 1, p. 177-183 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
92 Downloads (Pure)
2018

Customizing poly(lactic-co-glycolic acid) particles for biomedical applications

Swider, E., Koshkina, O., Tel, J., Cruz, L. J., de Vries, I. J. M. & Srinivas, M., Jun 2018, In : Acta Biomaterialia. 73, June 2018, p. 38-51 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
57 Citations (Scopus)
1 Downloads (Pure)

Injectable biomimetic hydrogels as tools for efficient T Cell expansion and delivery

Weiden, J., Voerman, D., Dölen, Y., Das, R. K., van Duffelen, A., Hammink, R., Eggermont, L. J., Rowan, A. E., Tel, J. & Figdor, C. G., 28 Nov 2018, In : Frontiers in Immunology. 9, 15 p., 2798.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
11 Citations (Scopus)
31 Downloads (Pure)

Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells

Wimmers, F., Subedi, N., van Buuringen, N., Heister, D., Vivié, J., Beeren-Reinieren, I., Woestenenk, R., Dolstra, H., Piruska, A., Jacobs, J. F. M., van Oudenaarden, A., Figdor, C. G., Huck, W. T. S., de Vries, I. J. M. & Tel, J., 1 Dec 2018, In : Nature Communications. 9, 1, 12 p., 3317.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
27 Citations (Scopus)
83 Downloads (Pure)
2017

Affinity-based purification of polyisocyanopeptide bioconjugates

Hammink, R., Eggermont, L. J., Zisis, T., Tel, J., Figdor, C. G., Rowan, A. E. & Blank, K. G., 18 Oct 2017, In : Bioconjugate Chemistry. 28, 10, p. 2560-2568 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

A membrane-anchored aptamer sensor for probing IFNγ secretion by single cells

Qiu, L., Wimmers, F., Weiden, J., Heus, H. A., Tel, J. & Figdor, C. G., 13 Jul 2017, In : Chemical Communications. 53, 57, p. 8066-8069 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
16 Citations (Scopus)
102 Downloads (Pure)

Controlling T-cell activation with synthetic dendritic cells using the multivalency effect

Hammink, R., Mandal, S., Eggermont, L. J., Nooteboom, M., Willems, P. H. G. M., Tel, J., Rowan, A. E., Figdor, C. G. & Blank, K. G., 31 Mar 2017, In : ACS Omega. 2, 3, p. 937-945 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
15 Citations (Scopus)
72 Downloads (Pure)
2016

A comparative study of the T cell stimulatory and polarizing capacity of human primary blood dendritic cell subsets

Sittig, S. P., Bakdash, G., Weiden, J., Sköld, A. E., Tel, J., Figdor, C. G., de Vries, I. J. M. & Schreibelt, G., 2016, In : Mediators of Inflammation. 2016, p. 1-11 3605643.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
25 Citations (Scopus)
76 Downloads (Pure)

Circulating apoptotic microparticles in systemic lupus erythematosus patients drive the activation of dendritic cell subsets and prime neutrophils for NETosis

Dieker, J., Tel, J., Pieterse, E., Thielen, A., Rother, N., Bakker, M., Fransen, J., Dijkman, H. B. P. M., Berden, J. H., de Vries, J. M., Hilbrands, L. B. & van der Vlag, J., Feb 2016, In : Arthritis & Rheumatology. 68, 2, p. 462-472 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
69 Citations (Scopus)
2 Downloads (Pure)

CLEC12A-mediated antigen uptake and cross-presentation by human dendritic cell subsets efficiently boost tumor-reactive T cell responses

Hutten, T. J. A., Thordardottir, S., Fredrix, H., Janssen, L., Woestenenk, R., Tel, J., Joosten, B., Cambi, A., Heemskerk, M. H. M., Franssen, G. M., Boerman, O. C., Bakker, L. B. H., Jansen, J. H., Schaap, N., Dolstra, H. & Hobo, W., 1 Oct 2016, In : Journal of Immunology. 197, 7, p. 2715-2725 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
21 Citations (Scopus)

Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses

Dölen, Y., Kreutz, M., Gileadi, U., Tel, J., Vasaturo, A., van Dinther, E. A. W., van Hout-Kuijer, M. A., Cerundolo, V. & Figdor, C. G., 5 Mar 2016, In : Oncoimmunology. 5, 1, 10 p., e1068493.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
31 Citations (Scopus)
1 Downloads (Pure)

Dendritic cells as vaccines: key regulators of tolerance and immunity

Tel, J., Benitez-Ribas, D., Janssen, E. M., Smits, E. L. J. & Jacobs, J. F. M., 2016, In : Mediators of Inflammation. 2016, 2 p., 5789725.

Research output: Contribution to journalArticleAcademic

1 Citation (Scopus)

Effective clinical responses in metastatic melanoma patients after vaccination with primary myeloid dendritic cells

Schreibelt, G., Bol, K. F., Westdorp, H., Wimmers, F., Aarntzen, E. H. J. G., Duiveman-de Boer, T., van de Rakt, M. W. M. M., Scharenborg, N. M., de Boer, A. J., Pots, J. M., Olde Nordkamp, M. A. M., van Oorschot, T. G. M., Tel, J., Winkels, G., Petry, K., Blokx, W. A. M., van Rossum, M. M., Welzen, M. E. B., Mus, R. D. M., Croockewit, S. A. J. & 8 others, Koornstra, R. H. T., Jacobs, J. F. M., Kelderman, S., Blank, C. U., Gerritsen, W. R., Punt, C. J. A., Figdor, C. G. & de Vries, I. J. M., 1 May 2016, In : Clinical Cancer Research. 22, 9, p. 2155-2166 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
99 Citations (Scopus)
2 Downloads (Pure)

Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination

Wimmers, F., Aarntzen, E. H. J. G., Duiveman-de Boer, T., Figdor, C. G., Jacobs, J. F. M., Tel, J. & de Vries, I. J. M., 5 Mar 2016, In : Oncoimmunology. 5, 1, 13 p., e1067745.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
18 Citations (Scopus)
1 Downloads (Pure)

Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition

Tel, J., Koornstra, R., de Haas, N., van Deutekom, V., Westdorp, H., Boudewijns, S., van Erp, N., Di Blasio, S., Gerritsen, W., Figdor, C. G., de Vries, I. J. M. & Hato, S. V., 14 Apr 2016, In : Journal of Translational Medicine. 14, 11 p., 14:88.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
60 Downloads (Pure)

Proteomics of human dendritic cell subsets reveals subset-specific surface markers and differential inflammasome function

Worah, K., Mathan, T. S. M., Vu Manh, T. P., Keerthikumar, S., Schreibelt, G., Tel, J., Duiveman-de Boer, T., Sköld, A. E., van Spriel, A. B., de Vries, I. J. M., Huynen, M. A., Wessels, H. J., Gloerich, J., Dalod, M., Lasonder, E., Figdor, C. G. & Buschow, S. I., 13 Sep 2016, In : Cell. 16, 11, p. 2953-66 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
25 Citations (Scopus)
5 Downloads (Pure)
2015

PLGA-encapsulated perfluorocarbon nanoparticles for simultaneous visualization of distinct cell populations by 19F MRI

Srinivas, M., Tel, J., Schreibelt, G., Bonetto, F., Cruz, L-J., Amiri, H., Heerschap, A., Figdor, C. G. & de Vries, I. J. M., 2015, In : Nanomedicine. 10, 15, p. 2339-48 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Polymer-based synthetic dendritic cells for tailoring robust and multifunctional T cell responses

Mandal, S., Hammink, R., Tel, J., Eksteen-Akeroyd, Z. H., Rowan, A. E., Blank, K. & Figdor, C. G., 20 Feb 2015, In : ACS Chemical Biology. 10, 2, p. 485-92 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Protamine-stabilized RNA as an ex vivo stimulant of primary human dendritic cell subsets

Sköld, A. E., van Beek, J. J. P., Sittig, S. P., Bakdash, G., Tel, J., Schreibelt, G. & de Vries, I. J. M., Nov 2015, In : Cancer Immunology, Immunotherapy. 64, 11, p. 1461-1473 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
23 Citations (Scopus)

Selective expression of the MAPK phosphatase Dusp9/MKP-4 in mouse plasmacytoid dendritic cells and regulation of IFN-β production

Niedzielska, M., Raffi, F. A. M., Tel, J., Muench, S., Jozefowski, K., Alati, N., Lahl, K., Mages, J., Billmeier, U., Schiemann, M., Appelt, U. K., Wirtz, S., Sparwasser, T., Hochrein, H., Figdor, C. G., Keyse, S. M. & Lang, R., 15 Aug 2015, In : Journal of Immunology. 195, 4, p. 1753-62 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
9 Downloads (Pure)
2014

An electro-coalescence chip for effective emulsion breaking in droplet microfluidics

Chokkalingam, V., Ma, Y., Thiele, J., Schalk, W., Tel, J. & Huck, W. T. S., 21 Jul 2014, In : Lab on a Chip. 14, 14, p. 2398-402 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)
1 Downloads (Pure)

Crosstalk between dendritic cell subsets and implications for dendritic cell-based anticancer immunotherapy

Bakdash, G., Schreurs, I., Schreibelt, G. & Tel, J., Jul 2014, In : Expert Review of Clinical Immunology. 10, 7, p. 915-926 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

One drop at a time : toward droplet microfluidics as a versatile tool for single-cell analysis

Rakszewska, A., Tel, J., Chokkalingam, V. & Huck, W. T., 2014, In : NPG Asia Materials. 6, e133, 10 p., e133.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
60 Citations (Scopus)
3 Downloads (Pure)

Towards efficient cancer immunotherapy: advances in developing artificial antigen-presenting cells

Eggermont, L. J., Paulis, L. E., Tel, J. & Figdor, C. G., Sep 2014, In : Trends in Biotechnology. 32, 9, p. 456-65 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

83 Citations (Scopus)

Tumoricidal activity of human dendritic cells

Tel, J., Anguille, S., Waterborg, C. E. J., Smits, E. L., Figdor, C. G. & de Vries, I. J. M., Jan 2014, In : Trends in Immunology. 35, 1, p. 38-46 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

43 Citations (Scopus)
2013

Antigen cross-presentation by dendritic cell subsets: one general or all sergeants?

Nierkens, S., Tel, J., Janssen, E. M. & Adema, G. J., Aug 2013, In : Trends in Immunology. 34, 8, p. 361-70 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

66 Citations (Scopus)
1 Downloads (Pure)

CD56 marks human dendritic cell subsets with cytotoxic potential

Roothans, D., Smits, E., Lion, E., Tel, J. & Anguille, S., 1 Feb 2013, In : Oncoimmunology. 2, 2, p. 1-3 e23037.

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets

Tel, J., Schreibelt, G., Sittig, S. P., Mathan, T. S. M., Buschow, S. I., Cruz, L-J., Lambeck, A. J. A., Figdor, C. G. & de Vries, I. J. M., 17 Jan 2013, In : Blood : the Journal of Hematology. 121, 3, p. 459-67 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

93 Citations (Scopus)

Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients

Tel, J., Aarntzen, E. H. J. G., Baba, T., Schreibelt, G., Schulte, B. M., Benitez-Ribas, D., Boerman, O. C., Croockewit, S., Oyen, W. J. G., van Rossum, M., Winkels, G., Coulie, P. G., Punt, C. J. A., Figdor, C. G. & de Vries, I. J. M., 1 Feb 2013, In : Cancer Research. 73, 3, p. 1063-75 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

182 Citations (Scopus)

Naturally circulating dendritic cells to vaccinate cancer patients

Bol, K. F., Tel, J., de Vries, I. J. M. & Figdor, C. G., 1 Mar 2013, In : Oncoimmunology. 2, 3, e23431.

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

Probing cellular heterogeneity in cytokine-secreting immune cells using droplet-based microfluidics

Chokkalingam, V., Tel, J., Wimmers, F., Liu, X., Semenov, S., Thiele, J., Figdor, C. G. & Huck, W. T. S., 21 Dec 2013, In : Lab on a Chip. 13, 24, p. 4740-4 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

111 Citations (Scopus)

Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion

Tel, J., Sittig, S. P., Blom, R. A. M., Cruz, L-J., Schreibelt, G., Figdor, C. G. & de Vries, I. J. M., 15 Nov 2013, In : Journal of Immunology. 191, 10, p. 5005-12 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

79 Citations (Scopus)
2012

Deciphering the message broadcast by tumor-infiltrating dendritic cells

Karthaus, N., Torensma, R. & Tel, J., Sep 2012, In : American Journal of Pathology. 181, 3, p. 733-42 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

38 Citations (Scopus)

Harnessing human plasmacytoid dendritic cells as professional APCs

Tel, J., van der Leun, A. M., Figdor, C. G., Torensma, R. & de Vries, L. J. M., Aug 2012, In : Cancer Immunology, Immunotherapy. 61, 8, p. 1279-88 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

42 Citations (Scopus)

Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities

Tel, J., Smits, E. L. J., Anguille, S., Joshi, R. N., Figdor, C. G. & de Vries, I. J. M., 8 Nov 2012, In : Blood : the Journal of Hematology. 120, 19, p. 3936-44 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

60 Citations (Scopus)

Interleukin-15-induced CD56(+) myeloid dendritic cells combine potent tumor antigen presentation with direct tumoricidal potential

Anguille, S., Lion, E., Tel, J., de Vries, I. J. M., Couderé, K., Fromm, P. D., Van Tendeloo, V. F., Smits, E. L. J. & Berneman, Z. N., 2012, In : PLoS ONE. 7, 12, p. e51851

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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41 Citations (Scopus)
37 Downloads (Pure)

Potential applications for plasmacytoid dendritic cells in cancer immunotherapy

Tel, J. & de Vries, I. J. M., Oct 2012, In : Immunotherapy. 4, 10, p. 979-982 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Targeted delivery of CpG ODN to CD32 on human and monkey plasmacytoid dendritic cells augments IFNα secretion

Tel, J., Beenhakker, N., Koopman, G., 't Hart, B., Mudde, G. C. & de Vries, I. J. M., Oct 2012, In : Immunobiology. 217, 10, p. 1017-1024 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
1 Downloads (Pure)

The chemotherapeutic drug oxaliplatin differentially affects blood DC function dependent on environmental cues

Tel, J., Hato, S. V., Torensma, R., Buschow, S. I., Figdor, C. G., Lesterhuis, W. J. & de Vries, I. J. M., Jul 2012, In : Cancer Immunology, Immunotherapy. 61, 7, p. 1101-11 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells

Schreibelt, G., Klinkenberg, L. J. J., Cruz, L. J., Tacken, P. J., Tel, J., Kreutz, M., Adema, G. J., Brown, G. D., Figdor, C. G. & de Vries, I. J. M., 8 Mar 2012, In : Blood : the Journal of Hematology. 119, 10, p. 2284-92 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

146 Citations (Scopus)
2011

DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells

Tel, J., Benitez-Ribas, D., Hoosemans, S., Cambi, A., Adema, G. J., Figdor, C. G., Tacken, P. J. & de Vries, I. J. M., Apr 2011, In : European Journal of Immunology. 41, 4, p. 1014-1023 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

48 Citations (Scopus)

IL-4 and IL-13 alter plasmacytoid dendritic cell responsiveness to CpG DNA and herpes simplex virus-1

Tel, J., Torensma, R., Figdor, C. G. & de Vries, I. J. M., Apr 2011, In : The Journal of Investigative Dermatology. 131, 4, p. 900-6 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Prophylactic vaccines mimic synthetic CpG oligonucleotides in their ability to modulate immune responses

de Vries, I. J. M., Tel, J., Benitez-Ribas, D., Torensma, R. & Figdor, C. G., Mar 2011, In : Molecular Immunology. 48, 6-7, p. 810-817 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)
2010

Cross-talk between human dendritic cell subsets influences expression of RNA sensors and inhibits picornavirus infection

Kramer, M., Schulte, B. M., Eleveld-Trancikova, D., van Hout-Kuijer, M. A., Toonen, L. W. J., Tel, J., de Vries, I. J. M., van Kuppeveld, F. J. M., Jansen, B. J. H. & Adema, G. J., 2010, In : Journal of Innate Immunity. 2, 4, p. 360-370 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Human plasmacytoid dendritic cells phagocytose, process, and present exogenous particulate antigen

Tel, J., Lambeck, A. J. A., Cruz, L. J., Tacken, P. J., de Vries, I. J. M. & Figdor, C. G., 15 Apr 2010, In : Journal of Immunology. 184, 8, p. 4276-83 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

58 Citations (Scopus)

Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy

Schreibelt, G., Tel, J., Sliepen, K. H. E. W. J., Benitez-Ribas, D., Figdor, C. G., Adema, G. J. & de Vries, I. J. M., Oct 2010, In : Cancer Immunology, Immunotherapy. 59, 10, p. 1573-82 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

162 Citations (Scopus)