• 4028 Citations
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Personal profile


“One of the most fascinating scientific trends of today is the merging of technology and biology: new technological solutions are inspired by biology, and technology is used to study, understand, and even steer biological processes.”

Research profile

Jaap den Toonder is full professor and Chair of the Microsystems research Section at Eindhoven University of Technology (TU/e). His group focuses its research on the investigation and development of innovative technological concepts and fabrication methods for microsystems for a wide range of applications. The application focus is on microfluidic chips, biomedical microdevices, and soft microrobotics. The group’s research approaches are often biologically inspired, translating principles from nature into technological innovations.

Den Toonder’s main personal research interests are microfluidics, mechanical properties of biological cells and tissues, nature-inspired micro-actuators and organs-on-chips to understand cancer. Den Toonder teaches courses on microfabrication methods, microfluidics, and heat and flow in microsystems, in which hands-on learning is a key element.


Academic background

Jaap den Toonder studied at Delft University of Technology where he obtained his MSc in Applied Mathematics (with honors). He received his PhD  (with honors) from the same university on a numerical/theoretical and experimental study of drag reduction in turbulent flows by polymer additives. In 1995, he joined Philips Research Laboratories in Eindhoven, and began working in mechanics of solid materials. He worked on a wide variety of applications, such as ceramic capacitors, optical storage systems, IC low-k materials, RF MEMS, soft electronics, biomedical devices, polymer MEMS, and micro-fluidics. In 2008, he became Chief Technologist, leading the R&D program on (micro-)fluidics, and (starting  2011) materials science and engineering. He was involved in research programs on molecular diagnostics, lab-on-chip, immersion lithography and energy applications.  

In addition to his job at Philips, Jaap den Toonder was a part-time professor at the TU/e  Materials Technology group between 2004 and 2013.  He has (co-)authored over 100 scientific papers, as well as over 40 patent applications. He is a member of the Editorial Board of Lab on a Chip, Micro-and Nanoelectromechanical Systems, Micromachines, and Biomimetics.

Den Toonder is recipient of an ERC Advancd Grant in 2019.

Affiliated with

  • Chairman of the Consortium Assembly of the human organ and Disease Model Technologies Institute (hDMT)
  • Chairman of the Board of Examiners, Department of Mechanical Engineering, TU/e
  • Scientific Advisor to Philips Research

Partners in (semi-)industry

  • Philips
  • ASML
  • Micronit
  • TNO

Fingerprint Dive into the research topics where Jaap M.J. den Toonder is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Microfluidics Engineering & Materials Science
Flow of fluids Engineering & Materials Science
Fluids Engineering & Materials Science
Magnetic fields Engineering & Materials Science
actuation Physics & Astronomy
Fabrication Engineering & Materials Science
Lab-on-a-chip Engineering & Materials Science
fluids Physics & Astronomy

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1995 2020

41 Downloads (Pure)

Climbing droplets driven by mechanowetting on transverse waves

De Jong, E., Wang, Y., den Toonder, J. & Onck, P. R., 14 Jun 2019, In : Science Advances. 5, 6, 8 p., eaaw0914.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
transverse waves
surface waves
dynamic control
2 Citations (Scopus)
52 Downloads (Pure)

Removal of microparticles by ciliated surfaces: an experimental study

Zhang, S., Wang, Y., Onck, P. R. & den Toonder, J. M. J., 8 Feb 2019, In : Advanced Functional Materials. 29, 6, 11 p., 1806434.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
water quality
12 Citations (Scopus)
107 Downloads (Pure)

A novel method to understand tumor cell invasion: integrating extracellular matrix mimicking layers in microfluidic chips by "selective curing"

Eslami Amirabadi, H., Sahebali, S., Frimat, J. M. S., Luttge, R. & den Toonder, J. M. J., 17 Oct 2017, In : Biomedical Microdevices. 19, 4, 11 p., 19:92.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)
70 Downloads (Pure)

Microfluidic magnetic bead conveyor belt

van Pelt, S., Frijns, A. J. H. & den Toonder, J. M. J., 2017, In : Lab on a Chip. 17, 22, p. 3826-3840

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Magnetic structure
Magnetic Fields
17 Citations (Scopus)
12 Downloads (Pure)

An integrated flex-microfluidic-Si chip device towards sweat sensing applications

Nie, C., Frijns, A. J. H., Zevenbergen, M. A. G. & den Toonder, J. M. J., 1 Jan 2016, In : Sensors and Actuators, B: Chemical. 227, p. 427-437

Research output: Contribution to journalArticleAcademicpeer-review


Unraveling forces on cells with artificial microscopic hairs

Jaap den Toonder (Recipient), 29 Mar 2019

Prize: ERCAdvancedScientific

Compact disk players


Heat and flow in microsystems

1/09/15 → …


Microfabrication methods

1/09/15 → …


Microfluidics put-to-work

1/09/15 → …


Press / Media

Battery-Free Sweat Sensor Technology Inspired by Plants

Jaap M.J. den Toonder


1 item of Media coverage

Press/Media: Expert Comment

Battery-Free Wearable Sweat Sensor Inspired by Plants

Jaap M.J. den Toonder


1 item of Media coverage

Press/Media: Expert Comment

Wearable sweat sensor thanks to battery-free 'water pump' inspired by plants

Jaap M.J. den Toonder


4 items of Media coverage

Press/Media: Expert Comment

Student theses

Active microfluidic mixing using integrated actuators

Author: Bos, F., 31 May 2007

Supervisor: den Toonder, J. (Supervisor 1), Anderson, P. (Supervisor 2) & van de Vosse, F. (Supervisor 2)

Student thesis: Master

Biomechanical regulation of endothelial phenotypic heterogeneity: arterial versus venous

Author: Norouzi, Y., 30 Sep 2013

Supervisor: Bouten, C. (Supervisor 1), van de Stolpe, A. (External person) (Supervisor 2) & den Toonder, J. (Supervisor 2)

Student thesis: Master

Characterisation of interfacial strength of low-k dielectric materials used in ICs

Author: Kouters, M., 31 Aug 2006

Supervisor: Geers, M. (Supervisor 1), den Toonder, J. (Supervisor 2), Peerlings, R. (Supervisor 2), van Hal, B. (Supervisor 2) & van Silfhout, R. (Supervisor 2)

Student thesis: Master

Characterization of freestanding thin film properties for RF-MEMS

Author: Burg, V., 30 Jun 2006

Supervisor: den Toonder, J. (Supervisor 1), van Dijken, A. R. (External person) (External coach), Hoefnagels, J. (Supervisor 2) & Geers, M. (Supervisor 2)

Student thesis: Master

Craze initiation in glassy polymer systems

Author: Bressers, O., 31 Jan 2002

Supervisor: Meijer, H. (Supervisor 1), van Melick, H. (Supervisor 2), Govaert, L. (Supervisor 2) & den Toonder, J. (External coach)

Student thesis: Master