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Personal profile

Quote

“Engineers need to truly become part of the medical world and understand the requirements and needs of clinicians to be able to deliver the improvements they are capable of.”

Research profile

Hessel Wijkstra is part-time Full Professor in the Signal Processing Systems group. He is also principal investigator in the department of Urology of the AMC in Amsterdam. His research focuses on medical imaging, especially contrast-enhanced ultrasound. His main interest is the clinical validation and implementation of advanced imaging technology as developed in the Signal Processing Systems group.

The focus of research is initially on prostate cancer - hard to visualize, usually only detected at a late stage and the second-highest cause of cancer deaths in men. Perfecting visualization techniques for prostate cancer would enable more effective screening, targeted biopsies and more timely and less radical treatments. The technology can be applied to other cancer types as well. Angiogenesis, the aberrant growth of new blood vessels that supplies growing tumors with the oxygen and nutrients to become malignant, is a factor in most cancers.

Wijkstra, an engineer among urologists and a urologist among engineers, believes engineers can help generate tremendous progress in medical care, improve diagnostics and treatment and help to realize more cost-effective care.

Academic background

Hessel Wijkstra holds an MSc and PhD in Electrical Engineering from Twente University. His interest in medical and clinical research led him to accept an appointment at the Urology department of the Radboud Medical Center in 1989. In 2004 he moved to the Urology department at the Academic Medical Center in Amsterdam in 2004. His intensive collaboration with Massimo Mischi at the Eindhoven University of Technology led to an appointment as part-time professor in the Signal Processing Systems group in 2010.

External positions

Principal Investigator, Academic Medical Centre Amsterdam

1 Oct 2003 → …

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Research Output 1989 2019

3-D multi-parametric contrast-enhanced ultrasound for the prediction of prostate cancer

Wildeboer, R. R., van Sloun, R. J. G., Huang, P., Wijkstra, H. & Mischi, M., 10 Jul 2019, In : Ultrasound in Medicine and Biology. 45, 10, p. 2713-2724

Research output: Contribution to journalArticleAcademicpeer-review

Prostatic Neoplasms
cancer
predictions
machine learning
Biopsy

555 - Contrast enhanced ultrasound for the localization of prostate cancer – correlation with radical prostatectomy specimens

Gayet, M., Postema, A. W., van Sloun, R., Wildeboer, R., Schalk, S., Mannaerts, C., Beerlage, H., Mischi, M. & Wijkstra, H., Mar 2019, In : European Urology Supplements. 18, 1, p. e739-e740 2 p.

Research output: Contribution to journalConference articleAcademicpeer-review

Open Access
Prostatectomy
Contrast Media
Ultrasonography
Prostatic Neoplasms
Prostate

Automated multiparametric localization of prostate cancer based on B-mode, shear-wave elastography, and contrast-enhanced ultrasound radiomics

Wildeboer, R. R., Mannaerts, C. K., van Sloun, R. J. G., Budäus, L., Tilki, D., Wijkstra, H., Salomon, G. & Mischi, M., 10 Oct 2019, In : European Radiology.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Elasticity Imaging Techniques
Prostatic Neoplasms
Machine Learning

Clinical evaluation of dispersion MRI for prostate cancer localization: a multicenter study

Turco, S., Lavini, C., Heijmink, S., Barentsz, J., Wijkstra, H. & Mischi, M., 2019 1 p.

Research output: Contribution to conferencePosterAcademic

Open Access
File
Multicenter Studies
Prostatic Neoplasms
Magnetic Resonance Imaging
Pharmacokinetics
Prostate
Prostate
Magnetic Resonance Imaging
Learning
Biopsy
France

Activities 2012 2013

  • 10 Contributed talk

28th Annual EAU congress, Milan

Hessel Wijkstra (Speaker)
18 Mar 2013

Activity: Talk or presentation typesContributed talkScientific

Workshop on ultrasound imaging for IGRT, Maastricht

Hessel Wijkstra (Speaker)
8 Feb 2013

Activity: Talk or presentation typesContributed talkScientific

Kongress der Deutschen Gesellschaft für Urologie e.V., 26 September 2012, Leipzig, Germany

Hessel Wijkstra (Speaker)
26 Sep 2012

Activity: Talk or presentation typesContributed talkScientific

27th Annual Advances in Contrast Ultrasound - ICUS Bubble Conference, 20 September 2012, Chicago, Illinois

Hessel Wijkstra (Speaker)
20 Sep 2012

Activity: Talk or presentation typesContributed talkScientific

30th World Congress of Endourology, 6 September 2012, Istanbul, Turkey

Hessel Wijkstra (Speaker)
6 Sep 2012

Activity: Talk or presentation typesContributed talkScientific

Student theses

An elastic registration method for validation of prostate cancer ultrasound imaging

Author: Schalk, S., 31 Aug 2011

Supervisor: Mischi, M. (Supervisor 1) & Wijkstra, H. (Supervisor 2)

Student thesis: Master

Classification and validation of contrast ultrasound dispersion maps compared with histology results

Author: Wu, K., 31 Oct 2014

Supervisor: Mischi, M. (Supervisor 1) & Wijkstra, H. (Supervisor 2)

Student thesis: Master

Estimation of acoustical coefficient of nonlinearity

Author: Zeng, Y., 24 May 2018

Supervisor: Mischi, M. (Supervisor 1) & Wijkstra, H. (Supervisor 2)

Student thesis: Master