Projects per year
Personal profile
Research profile
Frans van de Vosse leads the research group Cardiovascular Biomechanics at the department of Biomedical Engineering. His research interests are related to the computational and experimental biomechanical analysis of the cardiovascular system and its application to clinical diagnosis and intervention, cardiovascular prostheses, extracorporeal systems and medical devices. Research at the Cardiovascular Biomechanics group is directed along the topics Blood in Motion, Heart at Work, and Vessels under Stress. The common denominators are the development of computational models, experimental techniques and medical devices, for clinical diagnosis, decision support, and intervention.
Academic background
Frans van de Vosse studied Applied Physics at Eindhoven University of Technology (TU/e, The Netherlands) where he obtained his MSc in 1982. He earned his PhD degree from the same university in 1987 on his thesis describing the numerical analysis of carotid artery flow. From 1987 to 2001, he was lecturer in fluid mechanics with the Materials Technology group in the TU/e department of Mechanical Engineering. In 2001 he was appointed full professor in Cardiovascular Biomechanics at the department of Biomedical engineering (BMT, TU/e).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Patient-centered Exploration for Reliable, Smart and Efficient Utilization of healthcare Services (PERSEUS)
van de Vosse, F. N. (Project Manager), Drost, V. (Project member), van Beek, K. (Project member) & de Winter, L. (Project member)
1/10/23 → 16/04/29
Project: Third tier
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PICASSO/TKI/PPS/BMT/1912P08
van de Vosse, F. N. (Project Manager), Wijntjes, P. (Project member) & Buck, C. M. A. (Project member)
1/01/20 → 31/12/25
Project: Third tier
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MEDICAID/TKI/PPS/BMT
van de Vosse, F. N. (Project Manager), Fasen, F. (Project member) & Nievergeld, A. H. M. (Project member)
2/01/18 → 30/09/23
Project: Research direct
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An analytical evaluation of imputation methods for enhancing cardiac care data integrity
Ganesan, R. (Corresponding author), Buck, C. M. A., Sun, C., van 't Veer, M., Dekker, L. R., van de Vosse, F. N. & Huberts, W., Jun 2026, In: Healthcare Analytics. 9, 19 p., 100452.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile67 Downloads (Pure) -
A Statistical Shape Modeling Approach for the Derivation of a Data-Driven Geometry-Aware Lumped Arterial Stenosis Model
Hilhorst, P. L. J., Verstraeten, S. C. F. P. M., Zając, K., Ganesan, R., van 't Veer, M., van de Vosse, F. N. & Huberts, W. (Corresponding author), Feb 2026, In: International Journal for Numerical Methods in Biomedical Engineering. 42, 2, 22 p., e70138.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)14 Downloads (Pure) -
Exploring three-dimensional reconstruction with Neural Radiance Field (NeRF) for coronary roadmap navigation and view-planning in X-ray coronary angiography: A feasibility study
Vermeer, A. J. E. (Corresponding author-nrf), Maas, K. W. H., McCaughan, V. M., Ruijters, D., Pezzotti, N., Vlaar, P. J. J., Tonino, P. A. L., van de Vosse, F. N., Vilanova, A. & Veer, van 't, M., Jul 2026, In: Computer Methods and Programs in Biomedicine. 281, 10 p., 109349.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Downloads (Pure) -
In silico analysis of patient specific coagulation and flow effects on fibrin clot formation
Cruts, J. M. H., Rezaeimoghaddam, M., Rachid, A., Bontempi, L., Arisz, R. A., van de Vosse, F. N. & Gijsen, F. J. H. (Corresponding author), 5 Apr 2026, In: Scientific Reports. 16, 1, 21 p., 16411.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
The hemodynamic impact of congenital heart diseases during fetal-to-neonatal transition: an in-silico investigation
van Willigen, B. G. (Corresponding author), Krabben, B. C., van der Hout-van der Jagt, M. B., Huberts, W. & van de Vosse, F. N., 30 Jan 2026, (E-pub ahead of print) In: Pediatric Research. XXResearch output: Contribution to journal › Article › Academic › peer-review
Open Access
Datasets
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Data underlying the publication: Generation of synthetic aortic valve stenosis geometries for in silico trials
Verstraeten, S. (Creator), Hoeijmakers, M. J. M. M. (Creator), Tonino, W. A. L. (Creator), Brüning, J. (Creator), Capelli, C. (Creator), van de Vosse, F. (Creator) & Huberts, W. (Creator), 4TU.Centre for Research Data, 12 Oct 2023
DOI: 10.4121/3f6a3788-96e6-4b81-b37b-f07eeec85965, https://data.4tu.nl/datasets/3f6a3788-96e6-4b81-b37b-f07eeec85965 and one more link, https://data.4tu.nl/datasets/3f6a3788-96e6-4b81-b37b-f07eeec85965/1 (show fewer)
Dataset
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The impact of shape uncertainty on aortic-valve pressure-drop computations: supplementary data files
Hoeijmakers, M. J. M. M. (Creator), Huberts, W. (Creator), Rutten, M. C. M. (Creator) & van de Vosse, F. N. (Creator), 4TU.Centre for Research Data, 11 Aug 2021
DOI: 10.4121/15043599, https://data.4tu.nl/articles/_/15043599
Dataset
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ValveValid
Eerdekens, R. (Creator), Hilhorst, P. L. J. (Creator), van 't Veer, M. (Contributor), van Wijngaarden, J. (Contributor), Verstraeten, S. (Contributor), Ganesan, R. (Contributor), Huberts, W. (Contributor), van de Vosse, F. (Contributor) & Tonino, W. A. L. (Contributor), Zenodo, Jul 2024
DOI: 10.5281/zenodo.11616538, https://zenodo.org/records/11616538
Dataset
Courses
Press/Media
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Are artificial wombs the future?
van Haren, J. & van de Vosse, F. N.
19/10/23
1 Media contribution
Press/Media: Public Engagement Activities
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Study Results from Eindhoven University of Technology in the Area of Cardiovascular Research Reported (Preclinical Validation of the Advection Diffusion Flow Estimation Method Using Computational Patient Specific Coronary Tree Phantoms)
24/08/23
1 item of Media coverage
Press/Media: Expert Comment
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Kunstmatige alternatieven voor vitale organen
van Haren, J., van de Vosse, F. N. & Delbressine, F. L. M.
15/05/23
1 item of Media coverage
Press/Media: Public Engagement Activities
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Recent Findings in Biomechanical Engineering Described by a Researcher from Eindhoven University of Technology (Scale-Resolving Simulations of Steady and Pulsatile Flow Through Healthy and Stenotic Heart Valves)
23/01/23
1 item of Media coverage
Press/Media: Expert Comment
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Te vroeg geboren? Dan nog even groeien in de kunstbaarmoeder
van Haren, J., van de Vosse, F. N. & Delbressine, F. L. M.
27/08/21
1 item of Media coverage
Press/Media: Public Engagement Activities
Thesis
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Tweedimensionale kanaalstromingen achter een vernauwing : numerieke en experimentele analyse
van de Vosse, F. N. (Author), Janssen, J. D. (Supervisor 1), Vossers, G. (Supervisor 2), van Steenhoven, A. A. (Supervisor 2), Sauren, A. A. H. J. (Supervisor 2) & van Dongen, M. E. H. (Supervisor 2), 28 Feb 1983Student thesis: Master
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