• 5995 Citations
1985 …2019
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Personal profile

Research profile

Frans van de Vosse leads the research group Cardiovascular Biomechanics at the department of Biomedical Engineering. His research interests are related to the computational and experimental biomechanical analysis of the cardiovascular system and its application to clinical diagnosis and intervention, cardiovascular prostheses, extracorporeal systems and medical devices. Research at the Cardiovascular Biomechanics group is directed along the topics Blood in Motion, Heart at Work, and Vessels under Stress. The common denominators are the development of computational models, experimental techniques and medical devices, for clinical diagnosis, decision support, and intervention.

Academic background

Frans van de Vosse studied Applied Physics at Eindhoven University of Technology (TU/e, The Netherlands) where he obtained his MSc in 1982. He earned his PhD degree from the same university in 1987 on his thesis describing the numerical analysis of carotid artery flow. From 1987 to 2001, he was lecturer in fluid mechanics with the Materials Technology group in the TU/e department of Mechanical Engineering. In 2001 he was appointed full professor in Cardiovascular Biomechanics at the department of Biomedical engineering (BMT, TU/e).

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Research Output 1985 2019

Mechanical analysis of aortic aneurysms using 3D ultrasound : towards patient-specific risk assessment

van Disseldorp, E. M. J., 10 Jan 2019, Eindhoven: Technische Universiteit Eindhoven. 178 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Open Access
Risk assessment
Open Access
Pathologic Constriction
Dynamic models
7 Citations

A novel angiographic quantification of aortic regurgitation after TAVR provides an accurate estimation of regurgitation fraction derived from cardiac magnetic resonance imaging

Abdel-Wahab, M., Abdelghani, M., Miyazaki, Y., Holy, E. W., Merten, C., Zachow, D., Tonino, W. A. L., Rutten, M. C. M., van de Vosse, F. N., Morel, M. A., Onuma, Y., Serruys, P. W., Richardt, G. & Soliman, O. I., 12 Feb 2018, In : JACC: Cardiovascular Interventions. 11, 3, p. 287-297 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Aortic Valve Insufficiency
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Area Under Curve
Sensitivity and Specificity
2 Citations

Effects of exercise modalities on central hemodynamics, arterial stiffness and cardiac function in cardiovascular disease: Systematic review and meta-analysis of randomized controlled trials

Zhang, Y., Qi, L., Xu, L., Sun, X., Liu, W., Zhou, S., van de Vosse, F. & Greenwald, S. E., 1 Jul 2018, In : PLoS ONE. 13, 7, 28 p., e0200829

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Vascular Stiffness
systematic review
cardiac output
1 Citations

Hemodynamic significance assessment of equivocal iliac artery stenoses by comparing duplex ultrasonography with intra-arterial pressure measurements

Heinen, S. G., de Boer, S. W., van den Heuvel, D. A., Huberts, W., Dekker, P., van de Vosse, F. N., Delhaas, T. & De Vries, J. P., 1 Feb 2018, In : Journal of Cardiovascular Surgery. 59, 1, p. 37-44 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Femoral Artery
Arterial Pressure
Pathologic Constriction

Student theses

(Semi)automatic quantification of the internal elastic lamina fenestrae in remodeling arteries

Author: Groen, H., 30 Sep 2005

Supervisor: ter Haar Romenij, B. (Supervisor 1), van Zandvoort, M. (Supervisor 2), de Mey, J. (External person) (Supervisor 2) & van de Vosse, F. (Supervisor 2)

Student thesis: Master

A biomechanical view on atrial fibrillation: feasibility of stretch-activated ectopic beats in the left atrium

Author: Meiburg, R., 30 Apr 2016

Supervisor: Bovendeerd, P. (Supervisor 1), Dekker, L. (Supervisor 2), Oomens, C. (Supervisor 2) & van de Vosse, F. (Supervisor 2)

Student thesis: Master

Active microfluidic mixing using integrated actuators

Author: Bos, F., 31 May 2007

Supervisor: den Toonder, J. (Supervisor 1), Anderson, P. (Supervisor 2) & van de Vosse, F. (Supervisor 2)

Student thesis: Master

A diffuse-interface model of a red blood cell in flow

Author: Jaensson, N., 30 Apr 2012

Supervisor: van de Vosse, F. (Supervisor 1), Anderson, P. (Supervisor 2), Hilbers, P. (Supervisor 2) & Toschi, F. (Supervisor 2)

Student thesis: Master