Projects per year
Personal profile
Research profile
Frans van de Vosse leads the research group Cardiovascular Biomechanics at the department of Biomedical Engineering. His research interests are related to the computational and experimental biomechanical analysis of the cardiovascular system and its application to clinical diagnosis and intervention, cardiovascular prostheses, extracorporeal systems and medical devices. Research at the Cardiovascular Biomechanics group is directed along the topics Blood in Motion, Heart at Work, and Vessels under Stress. The common denominators are the development of computational models, experimental techniques and medical devices, for clinical diagnosis, decision support, and intervention.
Academic background
Frans van de Vosse studied Applied Physics at Eindhoven University of Technology (TU/e, The Netherlands) where he obtained his MSc in 1982. He earned his PhD degree from the same university in 1987 on his thesis describing the numerical analysis of carotid artery flow. From 1987 to 2001, he was lecturer in fluid mechanics with the Materials Technology group in the TU/e department of Mechanical Engineering. In 2001 he was appointed full professor in Cardiovascular Biomechanics at the department of Biomedical engineering (BMT, TU/e).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Patient-centered Exploration for Reliable, Smart and Efficient Utilization of healthcare Services (PERSEUS)
van de Vosse, F. N. (Project Manager), Drost, V. (Project member), van Beek, K. (Project member) & de Winter, L. (Project member)
1/10/23 → 16/04/29
Project: Third tier
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PICASSO/TKI/PPS/BMT/1912P08
van de Vosse, F. N. (Project Manager), Wijntjes, P. (Project member) & Buck, C. M. A. (Project member)
1/01/20 → 31/12/25
Project: Third tier
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MEDICAID/TKI/PPS/BMT
van de Vosse, F. N. (Project Manager), Fasen, F. (Project member) & Nievergeld, A. H. M. (Project member)
2/01/18 → 30/09/23
Project: Research direct
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A Multiscale Mathematical Model for Fetal Gas Transport and Regulatory Systems During Second Half of Pregnancy
van Willigen, B. G. (Corresponding author), van der Hout-van der Jagt, M. B., Huberts, W. & van de Vosse, F. N., Jan 2025, In: International Journal for Numerical Methods in Biomedical Engineering. 41, 1, 19 p., e3881.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile30 Downloads (Pure) -
A virtual population cohort approach for fetal cardiac valve modeling
van Willigen, B. G. (Corresponding author), van Osta, N., van der Hout-van der Jagt, M. B., van de Vosse, F. N. & Huberts, W., Jun 2025, In: Journal of Computational Science. 88, 10 p., 102606.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Downloads (Pure) -
Corrigendum to “A geometry-based model for non-invasive estimation of pressure gradients over iliac artery stenosis” [J. Biomech. 92 (2019) 67–75]
Heinen, S. G. H. (Corresponding author), van den Heuvel, D. A. F., de Vries, J. P. P. M., van de Vosse, F. N., Delhaas, T. & Huberts, W., Jan 2025, In: Journal of Biomechanics. 178, 1 p., 112248.Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review
Open AccessFile -
Longitudinal ultrasound-based fluid–structure interaction study on hemodynamics and wall mechanics in abdominal aortic aneurysms
Fonken, J. (Corresponding author), Timmer, T., Nievergeld, A., Thirugnanasambandam, M., van Sambeek, M., van de Vosse, F. & Lopata, R., Sept 2025, In: Computers in Biology and Medicine. 195, 12 p., 110486.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Sensitivity analysis for exploring the variability and parameter landscape in virtual patient cohorts of multi-vessel coronary artery disease
Hilhorst, P., van de Wouw, B., Zajac, K., van 't Veer, M., Tonino, P., van de Vosse, F. & Huberts, W. (Corresponding author), 2 Apr 2025, In: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 383, 2293, 20240230.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)1 Downloads (Pure)
Datasets
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ValveValid
Eerdekens, R. (Creator), Hilhorst, P. L. J. (Creator), van 't Veer, M. (Contributor), van Wijngaarden, J. (Contributor), Verstraeten, S. (Contributor), Ganesan, R. (Contributor), Huberts, W. (Contributor), van de Vosse, F. (Contributor) & Tonino, W. A. L. (Contributor), Zenodo, Jul 2024
DOI: 10.5281/zenodo.11616538, https://zenodo.org/records/11616538
Dataset
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Data underlying the publication: Generation of synthetic aortic valve stenosis geometries for in silico trials
Verstraeten, S. (Creator), Hoeijmakers, M. J. M. M. (Creator), Tonino, W. A. L. (Creator), Brüning, J. (Creator), Capelli, C. (Creator), van de Vosse, F. (Creator) & Huberts, W. (Creator), 4TU.Centre for Research Data, 12 Oct 2023
DOI: 10.4121/3f6a3788-96e6-4b81-b37b-f07eeec85965, https://data.4tu.nl/datasets/3f6a3788-96e6-4b81-b37b-f07eeec85965 and one more link, https://data.4tu.nl/datasets/3f6a3788-96e6-4b81-b37b-f07eeec85965/1 (show fewer)
Dataset
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The impact of shape uncertainty on aortic-valve pressure-drop computations: supplementary data files
Hoeijmakers, M. J. M. M. (Creator), Huberts, W. (Creator), Rutten, M. C. M. (Creator) & van de Vosse, F. N. (Creator), 4TU.Centre for Research Data, 11 Aug 2021
DOI: 10.4121/15043599, https://data.4tu.nl/articles/_/15043599
Dataset
Courses
Press/Media
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Are artificial wombs the future?
van Haren, J. & van de Vosse, F. N.
19/10/23
1 Media contribution
Press/Media: Public Engagement Activities
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Kunstmatige alternatieven voor vitale organen
van Haren, J., van de Vosse, F. N. & Delbressine, F. L. M.
15/05/23
1 item of Media coverage
Press/Media: Public Engagement Activities
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Recent Findings in Biomechanical Engineering Described by a Researcher from Eindhoven University of Technology (Scale-Resolving Simulations of Steady and Pulsatile Flow Through Healthy and Stenotic Heart Valves)
23/01/23
1 item of Media coverage
Press/Media: Expert Comment
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Te vroeg geboren? Dan nog even groeien in de kunstbaarmoeder
van Haren, J., van de Vosse, F. N. & Delbressine, F. L. M.
27/08/21
1 item of Media coverage
Press/Media: Public Engagement Activities
Thesis
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Tweedimensionale kanaalstromingen achter een vernauwing : numerieke en experimentele analyse
van de Vosse, F. N. (Author), Janssen, J. D. (Supervisor 1), Vossers, G. (Supervisor 2), van Steenhoven, A. A. (Supervisor 2), Sauren, A. A. H. J. (Supervisor 2) & van Dongen, M. E. H. (Supervisor 2), 28 Feb 1983Student thesis: Master
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