• 271 Citations
20102020

Research output per year

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Research Output

  • 271 Citations
  • 15 Article
  • 1 Conference contribution
  • 1 Review article
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Article
2020

Patient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Eduati, F., Jaaks, P., Wappler, J., Cramer, T., Merten, C. A., Garnett, M. J. & Saez-Rodriguez, J., Feb 2020, In : Molecular Systems Biology. 16, 2, 13 p., e8664.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
32 Downloads (Pure)
2018

A microfluidics platform for combinatorial drug screening on cancer biopsies

Eduati, F., Utharala, R., Madhavan, D., Neumann, U. P., Longerich, T., Cramer, T., Saez-Rodriguez, J. & Merten, C. A., 22 Jun 2018, In : Nature Communications. 9, 1, 13 p., 2434.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
32 Citations (Scopus)
136 Downloads (Pure)
2017

Drug resistance mechanisms in colorectal cancer dissected with cell type-specific dynamic logic models

Eduati, F., Doldàn-Martelli, V., Klinger, B., Cokelaer, T., Sieber, A., Kogera, F., Dorel, M., Garnett, M. J., Blüthgen, N. & Saez-Rodriguez, J., 15 Jun 2017, In : Cancer Research. 77, 12, p. 3364-3375 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
38 Citations (Scopus)

Logic modeling in quantitative systems pharmacology

Traynard, P., Tobalina, L., Eduati, F., Calzone, L. & Saez-Rodriguez, J., 1 Aug 2017, In : CPT: Pharmacometrics & Systems Pharmacology. 6, 8, p. 499-511 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Citations (Scopus)
36 Downloads (Pure)
2016

A rule-based model of insulin signalling pathway

Di Camillo, B., Carlon, A., Eduati, F. & Toffolo, G. M., 1 Jun 2016, In : BMC Systems Biology. 10, 1, 13 p., 38.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
7 Citations (Scopus)
6 Downloads (Pure)

Rapid identification of optimal drug combinations for personalized cancer therapy using microfluidics

Eduati, F., Utharala, R., Madhavan, D., Neumann, U. P., Cramer, T., Saez-Rodriguez, J. & Merten, C. A., 14 Dec 2016, In : bioRxiv. 34 p.

Research output: Contribution to journalArticleAcademic

Open Access
File
68 Downloads (Pure)
2015

DREAMTools: a Python package for scoring collaborative challenges

Cokelaer, T., Bansal, M., Bare, C., Bilal, E., Bot, B. M., Chaibub Neto, E., Eduati, F., de la Fuente, A., Gönen, M., Hill, S. M., Hoff, B., Karr, J. R., Küffner, R., Menden, M. P., Meyer, P., Norel, R., Pratap, A., Prill, R. J., Weirauch, M. T., Costello, J. C. & 2 others, Stolovitzky, G. & Saez-Rodriguez, J., 2015, In : F1000Research. 4, 28 p., 1030.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
228 Downloads (Pure)

Learning Boolean logic models of signaling networks with ASP

Videla, S., Guziolowski, C., Eduati, F., Thiele, S., Gebser, M., Nicolas, J., Saez-Rodriguez, J., Schaub, T. & Siegel, A., 27 Sep 2015, In : Theoretical Computer Science. 599, September, p. 79-101 23 p., 10393.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
11 Citations (Scopus)
10 Downloads (Pure)

Prediction of human population responses to toxic compounds by a collaborative competition

Eduati, F., Mangravite, L. M., Wang, T., Tang, H., Bare, J. C., Huang, R., Norman, T., Kellen, M., Menden, M. P., Yang, J., Zhan, X., Zhong, R., Xiao, G., Xia, M., Abdo, N., Kosyk, O., Friend, S., Dearry, A., Simeonov, A., Tice, R. R. & 6 others, Rusyn, I., Wright, F. A., Stolovitzky, G., Xie, Y., Saez-Rodriguez, J. & NIEHS-NCATS-UNC DREAM Toxicogenetics Collaboration, 10 Sep 2015, In : Nature Biotechnology. 33, 9, p. 933-940 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
53 Citations (Scopus)
2 Downloads (Pure)
2014

Leucine modulates dynamic phosphorylation events in insulin signaling pathway and enhances insulin-dependent glycogen synthesis in human skeletal muscle cells

Di Camillo, B., Eduati, F., Nair, S. K., Avogaro, A. & Toffolo, G. M., 20 Mar 2014, In : BMC Cell BIology. 15, 9 p., 9.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
10 Citations (Scopus)
18 Downloads (Pure)
2013

Exhaustively characterizing feasible logic models of a signaling network using Answer Set Programming

Guziolowski, C., Videla, S., Eduati, F., Thiele, S., Cokelaer, T., Siegel, A. & Saez-Rodriguez, J., 15 Sep 2013, In : Bioinformatics. 29, 18, p. 2320-6 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
39 Citations (Scopus)
37 Downloads (Pure)
2012

Dynamic modeling of miRNA-mediated feed-forward loops

Eduati, F., Di Camillo, B., Karbiener, M., Scheideler, M., Corà, D., Caselle, M. & Toffolo, G. M., Feb 2012, In : Journal of Computational Biology. 19, 2, p. 188-199 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Integrating literature-constrained and data-driven inference of signalling networks

Eduati, F., De Las Rivas, J., Di Camillo, B., Toffolo, G. & Saez-Rodriguez, J., 15 Sep 2012, In : Bioinformatics. 28, 18, p. 2311-2317 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
25 Citations (Scopus)
64 Downloads (Pure)
2011

Adaptation as a genome-wide autoregulatory principle in the stress response of yeast

De Palo, G., Eduati, F., Zampieri, M., Di Camillo, B., Toffolo, G. & Altafini, C., Jul 2011, In : IET Systems Biology. 5, 4, p. 269-79 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2010

A Boolean approach to linear prediction for signaling network modeling

Eduati, F., Corradin, A., Di Camillo, B. & Toffolo, G., 16 Sep 2010, In : PLoS ONE. 5, 9

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
14 Citations (Scopus)