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Personal profile

Quote

"Pressure ulcers represent a chronic condition reflecting Quality of Care and Patient Safety. My aim is to adopt bioengineering strategies to detect early tissue damage and inform effective clinical practice."

Research profile

Dan Bader has been part-time Professor of Soft Tissue Remodeling at the TU/e department of Biomedical Engineering since 2000 in the research group Soft Tissue Engineering and Mechanobiology. He also holds the chair of Bioengineering and Tissue Health at the Faculty of Health Sciences of the University of Southampton (UK), where he has hosted a number of TU/e intern students. In collaboration with Prof. Oomens, he has supported the experimental research associated with biomechanical conditioning of cell seeded constructs for tissue engineering, as well as bioengineering solutions in the prevention of pressure ulcers (PUs). The latter studies, involving both skin and muscle tissues, have identified the physiological mechanisms associated with mechanical-induced tissue damage, using a multi-scale approach, and have established design solutions for PU prevention. Dan Bader is PI of the UK EPSRC funded Network on “Medical Devices and Vulnerable Skin” (2014-19), involving collaborative projects with academics, clinicians and industrialists.

Academic background

Dan Bader studied Physics (BSc) and Medical Physics (MSc) at the Universities of Liverpool and Aberdeen, followed by a PhD in Southampton. He moved to Oxford University, to research the engineering aspects of pressure ulcer prevention. He later moved to Queen Mary, University of London (QMUL) as a lecturer and core research staff member in the IRC in Biomedical Materials, and in 1999 became the first Professor of Medical Engineering at QMUL. In 2011, he was appointed Professor of Bioengineering and Tissue Health in the University of Southampton. Since 2000, he has been part-time Professor in Soft Tissue Remodeling at TU/e. He is Editor-in-Chief for the Journal of Tissue Viability and Elected Member of World Council of Biomechanics (2006-).

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Research Output 1997 2019

Evaluating aetiological processes for monitoring and detection of deep tissue injury

Traa, W. A., 19 Feb 2019, Eindhoven: Technische Universiteit Eindhoven. 140 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Open Access
File
2 Citations (Scopus)

Investigating the influence of intermittent and continuous mechanical loading on skin through non-invasive sampling of IL-1α

Soetens, J. F. J., Worsley, P. R., Bader, D. L. & Oomens, C. W. J., 1 Feb 2019, In : Journal of Tissue Viability. 28, 1, p. 1-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pressure Ulcer
Sacrum
Skin
Sebum
Cytokines

Mechanical and biochemical response of human skin to diverse loading conditions

Soetens, J. F. J., 18 Jun 2019, Eindhoven: Technische Universiteit Eindhoven. 112 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Open Access
File
Skin
2 Citations (Scopus)

Myoglobin and troponin concentrations are increased in early stage deep tissue injury

Traa, W. A., Strijkers, G. J., Bader, D. L. & Oomens, C. W. J., 1 Apr 2019, In : Journal of the Mechanical Behavior of Biomedical Materials. 92, p. 50-57 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Troponin
Myoglobin
Blood
Tissue
Biomarkers

The expression of anaerobic metabolites in sweat and sebum from human skin subjected to intermittent and continuous mechanical loading

Soetens, J. F. J., Worsley, P. R., Herniman, J. M., Langley, G. J., Bader, D. L. & Oomens, C. W. J., 21 Oct 2019, In : Journal of Tissue Viability.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Sebum
Sweat
Pressure Ulcer
Skin
Pyruvic Acid

Press / Media

Detecting pressure ulcers in sweat and sebum

Dan Bader

17/06/19

1 item of media coverage

Press/Media: Expert Comment

Skin Integrity and Infection Prevention Conference hailed success

Dan Bader

6/07/1611/07/16

3 items of media coverage

Press/Media: Expert Comment

Student theses

Assessment of a new generation of IC beds for pressure ulcer prevention

Author: Broek, M., 30 Jun 2012

Supervisor: Oomens, C. (Supervisor 1), Bader, D. (Supervisor 2) & Baaijens, F. (Supervisor 2)

Student thesis: Master

Biochemical marker for early and objective detection of grade 1 pressure ulcers

Author: van der Lans, M., 31 Aug 2007

Supervisor: Baaijens, F. (Supervisor 1), Bader, D. (Supervisor 2), Oomens, C. (Supervisor 2), Bosboom, E. (Supervisor 2) & Bronneberg, D. (Supervisor 2)

Student thesis: Master

Collagen orientation in chondrocyte cultures in vitro

Author: Wouters, W., 31 Aug 2010

Supervisor: Ito, K. (Supervisor 1), Bader, D. (External coach), van Donkelaar, C. (Supervisor 2) & Kock, L. (Supervisor 2)

Student thesis: Master

Early detection of deep tissue injury: the development of a new experimental set-up and a first step towards a 3D finite element model

Author: Traa, W., 31 Jan 2014

Supervisor: Baaijens, F. (Supervisor 1), Oomens, C. (Supervisor 2), Bader, D. (Supervisor 2) & van Donkelaar, C. (Supervisor 2)

Student thesis: Master

Static loading of chondrocyte-agarose constructs

Author: Chávarri Leal, C., 30 Apr 2013

Supervisor: Oomens, C. (Supervisor 1), Bader, D. (Supervisor 2), Ito, K. (Supervisor 2), van Turnhout, M. (Supervisor 2) & van Donkelaar, C. (Supervisor 2)

Student thesis: Master