If you made any changes in Pure these will be visible here soon.

Research Output

[42] Strategies to assess phosphoprotein phosphatase and protein kinase- mediated regulation of the cytoskeleton

Eriksson, J. E., Toivola, D. M., Sahlgren, C., Mikhailov, A. & Härmälä-Braskén, A-S., 1998, Molecular Motors and the Cytoskeleton Part B. Vallee, R. B. (ed.). San Diego, Calif: Academic Press Inc., p. 542-569 (Methods in Enzymology; vol. 298).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

16 Citations (Scopus)
Open Access
File
17 Citations (Scopus)
59 Downloads (Pure)

Active targeting of mesoporous silica drug carriers enhances γ-secretase inhibitor efficacy in an in vivo model for breast cancer

Wittig, R., Rosenholm, J. M., Haartman, Von, E., Hemming, J., Genze, F., Bergman, L., Simmet, T., Lindén, M. & Sahlgren, C., 2014, In : Nanomedicine. 9, 7, p. 971-987

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

A microfluidic oxygen gradient device to assess EMT state and migrational responses of cancer cells

Sleeboom, J., van der Doelen, K., Kruyt, F., Sahlgren, C. M. & den Toonder, J. M. J., Jul 2019.

Research output: Contribution to conferencePosterAcademic

A microfluidic oxygen gradient device to assess EMT state and migrational responses of cancer cells

Sleeboom, J., van der Doelen, K., Kruyt, F., Sahlgren, C. M. & den Toonder, J. M. J., Jun 2019.

Research output: Contribution to conferencePosterAcademic

File
11 Downloads (Pure)

Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes

Paatero, I., Casals, E., Niemi, R., Özliseli, E., Rosenholm, J. M. & Sahlgren, C., 1 Dec 2017, In : Scientific Reports. 7, 1, 8423.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
15 Citations (Scopus)
69 Downloads (Pure)

A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death

Sahlgren, C. M., Pallari, H-M., He, T., Chou, Y-H., Goldman, R. D. & Eriksson, J. E., 2006, In : EMBO Journal. 25, 20, p. 4808-4819

Research output: Contribution to journalArticleAcademicpeer-review

119 Citations (Scopus)
File
53 Downloads (Pure)

A novel breast-cancer model of early stage invasion

Sleeboom, J. J. F., Sahlgren, C. M. & den Toonder, J. M. J., 2 May 2017.

Research output: Contribution to conferencePosterAcademic

File
67 Downloads (Pure)

Astrocytes negatively regulate neurogenesis through the Jagged1-mediated notch pathway

Wilhelmsson, U., Faiz, M., Pablo, De, Y., Sjöqvist, M., Andersson, D., Widestrand, Å., Potokar, M., Stenovec, M., Smith, P. L. P., Shinjyo, N., Pekny, T., Zorec, R., Ståhlberg, A., Pekna, M., Sahlgren, C. & Pekny, M., 2012, In : Stem Cells. 30, 10, p. 2320-2329

Research output: Contribution to journalArticleAcademicpeer-review

81 Citations (Scopus)
1 Downloads (Pure)
Open Access
File
27 Downloads (Pure)

Cancer-cell-specific induction of apoptosis using mesoporous silica nanoparticles as drug-delivery vectors

Rosenholm, J. M., Peuhu, E., Bate-Eya, L. T., Eriksson, J. E., Sahlgren, C. & Lindén, M., 2010, In : Small. 6, 11, p. 1234-1241

Research output: Contribution to journalArticleAcademicpeer-review

135 Citations (Scopus)

Cancer-cell targeting and cell-specific delivery by mesoporous silica nanoparticles

Rosenholm, J. M., Sahlgren, C. & Lindén, M., 2010, In : Journal of Materials Chemistry. 20, 14, p. 2707-2713

Research output: Contribution to journalArticleAcademicpeer-review

81 Citations (Scopus)
1 Downloads (Pure)

Cancer stem cell migration in an oxygen gradient characterized using a microfluidic device

Sleeboom, J. J. F., Sahlgren, C. M. & Den Toonder, J. M. J., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, Vol. 3. p. 1517-1520 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Cardiac progenitor cells and the interplay with their microenvironment

Mauretti, A., Spaans, S., Bax, N. A. M., Sahlgren, C. & Bouten, C. V. C., 2017, In : Stem Cells International. 2017, 20 p., 7471582.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
16 Citations (Scopus)
93 Downloads (Pure)

Cardiac stem cell mechanosome and mechanosensitivity develop with differentiation

Mauretti, A., Bax, N. A. M., van Marion, M. H., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., 28 Jun 2016.

Research output: Contribution to conferencePosterAcademic

Open Access
File
30 Downloads (Pure)

Cardiac stem cell mechanosome and mechanosensitivity develop with differentiation

Mauretti, A., Bax, N. A. M., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., 22 Mar 2016.

Research output: Contribution to conferencePosterAcademic

Open Access
File
88 Downloads (Pure)

Cardiomyocyte progenitor cell mechanoresponse unrevealed: strain avoidance and mechanosome development.

Mauretti, A., Bax, N. A. M., van Marion, M. H., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., 12 Sep 2016, In : Integrative Biology. 8, 9, p. 991-1001 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
17 Downloads (Pure)

Cdk5 regulates the organization of nestin and its association with p35

Sahlgren, C. M., Mikhailov, A., Vaittinen, S., Kalimo, H., Pant, H. C. & Eriksson, J. E., 2003, In : Molecular and cellular biology. 23, 14, p. 5090-5106

Research output: Contribution to journalArticleAcademicpeer-review

113 Citations (Scopus)

Cell-matrix interactions in cardiac progenitor cell niche

Mauretti, A., Sahlgren, C. M., Baaijens, F. P. T. & Bouten, C. V. C., 2014.

Research output: Contribution to conferencePosterAcademic

11 Downloads (Pure)

Cell-matrix interactions in cardiomyocyte progenitor cells upon cyclic strain

Mauretti, A., Sahlgren, C. M., Baaijens, F. P. T. & Bouten, C. V. C., May 2015.

Research output: Contribution to conferencePosterAcademic

Open Access
File
58 Downloads (Pure)

Combination of magnetic field and surface functionalization for reaching synergistic effects in cellular labeling by magnetic core-shell nanospheres

Gulin-Sarfraz, T., Zhang, J., Desai, D., Teuho, J., Sarfraz, J., Jiang, H., Zhang, C., Sahlgren, C., Lindén, M., Gu, H. & Rosenholm, J. M., 1 Dec 2014, In : Biomaterials Science. 2, 12, p. 1750-1760 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
Open Access

Core-shell designs of photoluminescent nanodiamonds with porous silica coatings for bioimaging and drug delivery, II : Application

Prabhakar, N., Näreoja, T., Haartman, Von, E., Karaman, D. S., Jiang, H., Koho, S., Dolenko, T. A., Hänninen, P. E., Vlasov, D. I., Ralchenko, V. G., Hosomi, S., Vlasov, I. I., Sahlgren, C. M. & Rosenholm, J. M., 2013, In : Special Publication - Royal Society of Chemistry. 5, 9, p. 3713-3722

Research output: Contribution to journalArticleAcademicpeer-review

74 Citations (Scopus)
1 Downloads (Pure)

Decoding breast cancer tissue-stroma interactions using species-specific sequencing

Chivukula, I. V., Ramsköld, D., Storvall, H., Anderberg, C., Jin, S., Mamaeva, V., Sahlgren, C. M., Pietras, K., Sandberg, R. & Lendahl, U., 2015, In : Breast cancer research : BCR. 17, p. 1-14 109.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
97 Downloads (Pure)

Decoding the PTM-switchboard of Notch

Antfolk, D., Antila, C., Kemppainen, K., Landor, S. K. J. & Sahlgren, C., 1 Dec 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 12, 21 p., 118507.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
32 Downloads (Pure)
Open Access
File
43 Downloads (Pure)

Fluid shear stress induces jagged1 Ligand clustering in endothelial cells.

Driessen, R. C. H., Bouten, C. V. C. & Sahlgren, C. M., 23 Jul 2016.

Research output: Contribution to conferenceAbstractAcademic

Genetically-encoded tools for cAMP probing and modulation in living systems

Paramonov, V. M., Mamaeva, V., Sahlgren, C. M. & Rivero-Müller, A., 2015, In : Frontiers in Pharmacology. 6, p. 1-21 196.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
17 Citations (Scopus)
80 Downloads (Pure)

High levels of Notch signaling down-regulate Numb and Numblike

Chapman, G., Liu, L., Sahlgren, C., Dahlqvist, C. & Lendahl, U., 2006, In : Journal of Cell Biology. 175, 4, p. 535-540 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

64 Citations (Scopus)

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms

Landor, S., Mutvei, A. P., Mamaeva, V., Jin, S., Busk, M., Borra, R., Grönroos, T. J., Kronqvist, P., Lendahl, U. & Sahlgren, C. M., 2011, In : Proceedings of the National Academy of Sciences of the United States of America (PNAS). 108, 46, p. 18814-18819

Research output: Contribution to journalArticleAcademicpeer-review

64 Citations (Scopus)

Influence of the assembly state on the functionality of a supramolecular jagged1-mimicking peptide additive

Putti, M., Stassen, O. M. J. A., Schotman, M. J. G., Sahlgren, C. M. & Dankers, P. Y. W., 3 May 2019, In : ACS Omega. 4, 5, p. 8178-8187 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
50 Downloads (Pure)

Inhibiting notch activity in breast cancer stem cells by glucose functionalized nanoparticles carrying γ-secretase inhibitors

Mamaeva, V., Niemi, R., Beck, M., Özliseli, E., Desai, D., Landor, S., Gronroos, T., Kronqvist, P., Pettersen, I. K. N., McCormack, E., Rosenholm, J. M., Linden, M. & Sahlgren, C. M., 1 May 2016, In : Molecular Therapy. 24, 5, p. 926-936 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
52 Citations (Scopus)
100 Downloads (Pure)

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells

Main, H., Lee, K. L., Yang, H., Haapa-Paananen, S., Edgren, H., Jin, S., Sahlgren, C., Kallioniemi, O., Poellinger, L., Lim, B. & Lendahl, U., 2010, In : Experimental Cell Research. 316, 9, p. 1610-1624

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)

Intermediate filament protein partnership in astrocytes

Eliasson, C., Sahlgren, C., Berthold, C-H., Stakeberg, J., Celis, J. E., Betsholtz, C. & Pekny, M., 1999, In : Journal of Biological Chemistry. 274, 34, p. 23996-24006 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

281 Citations (Scopus)
Open Access
File
11 Downloads (Pure)

Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells

Braune, E-B., Tsoi, Y. L., Phoon, Y. P., Landor, S., Silva Cascales, H., Ramsköld, D., Deng, Q., Lindqvist, A., Lian, X., Sahlgren, C. M., Jin, S-B. & Lendahl, U., 10 May 2016, In : Stem cell reports. 6, 5, p. 643-51 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
16 Citations (Scopus)
74 Downloads (Pure)

Mapping of the three-dimensional lymphatic microvasculature in bladder tumours using light-sheet microscopy

Tanaka, N., Kaczynska, D., Kanatani, S., Sahlgren, C., Mitura, P., Stepulak, A., Miyakawa, A., Wiklund, P. & Uhlén, P., 1 Apr 2018, In : British Journal of Cancer. 118, 7, p. 995-999 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
66 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
62 Downloads (Pure)

Mechanosensitivity of cardiomyocyte progenitor cells: the strain response in 2D and 3D environments

Bax, N. A. M., Mauretti, A., Van Marion, M. H., Van Turnhout, M. C., Van der Schaft, D. W. J., Sahlgren, C. M., Goumans, M. J. T. H. & Bouten, C. V. C., 1 Jul 2016, In : Cardiovascular Research. 111, suppl 1, p. S94-S94 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
File
45 Downloads (Pure)

Mechanosensitivity of CMPCs :strain response in 2D and 3D environments

Bax, N. A. M., Mauretti, A., van Marion, M. H., van Turnhout, M. C., van der Schaft, D. W. J., Goumans, M. J. T. H., Sahlgren, C. M. & Bouten, C. V. C., Sep 2016, International Society for Applied Cardiovascular Biology : ISACB, 7-10 September, Banff, Canada.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

8 Downloads (Pure)

Mechanosensitivity of Jagged–Notch signaling can induce a switch-type behavior in vascular homeostasis

Loerakker, S., Stassen, O. M. J. A., ter Huurne, F. M., Boareto, M., Bouten, C. V. C. & Sahlgren, C. M., 17 Apr 2018, In : Proceedings of the National Academy of Sciences of the United States of America (PNAS). 115, 16, p. E3682-E3691 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
10 Citations (Scopus)
59 Downloads (Pure)

Mesoporous silica nanoparticle-based substrates for cell directed delivery of Notch signalling modulators to control myoblast differentiation

Böcking, D., Wiltschka, O., Niinimäki, J., Shokry, H., Brenner, R., Lindén, M. & Sahlgren, C., 2014, In : Nanoscale. 6, 3, p. 1490-1498 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)
2 Downloads (Pure)

Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of notch signaling in cancer

Mamaeva, V., Rosenholm, J. M., Bate-Eya, L. T., Bergman, L., Peuhu, E., Duchanoy, A., Fortelius, L. E., Landor, S., Lindén, M. & Sahlgren, C., 31 May 2011, In : Molecular Therapy. 19, 8, p. 1538-1546

Research output: Contribution to journalArticleAcademicpeer-review

150 Citations (Scopus)
1 Downloads (Pure)

Mesoporous silica nanoparticles in medicine : recent advances

Mamaeva, V., Sahlgren, C. & Lindén, M., May 2013, In : Advanced Drug Delivery Reviews. 65, 5, p. 689-702 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

416 Citations (Scopus)
1 Downloads (Pure)

Mesoporous silica nanoparticles in tissue engineering : a perspective

Rosenholm, J. M., Zhang, J., Linden, M. & Sahlgren, C. M., 1 Feb 2016, In : Nanomedicine. 11, 4, p. 391-402 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Mesoporous silica particle-PLA-PANI hybrid scaffolds for cell-directed intracellular drug delivery and tissue vascularization

Shokry, H., Vanamo, U., Wiltschka, O., Niinimäki, J., Lerche, M., Levon, K., Linden, M. & Sahlgren, C. M., 14 Sep 2015, In : Nanoscale. 7, 34, p. 14434-43 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)