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Personal profile


“As medical physicist I focus on improving the quality, safety and cost-effectiveness of healthcare – by developing and implementing new technology for diagnosis and treatment of patients.”

Research profile

Carola van Pul is an Associate Professor and Chair of Clinical Physics at Eindhoven University of Technology (TU/e). Her fields of expertise concerns general clinical physics - for radiology, nuclear medicine, radiation protection, with a particular specialization in medical technology used for mother-and-child care. 

Next to her clinical tasks as clinical physicist in MMC, Carola is an active researcher. Focus of her research is currently on patient monitoring for (neonatal) intensive care and complex patient monitoring and medical alarm systems using ICT networks. New monitoring techniques are developed for improving diagnosis but also data mining approaches are investigated to reduce the high number of alarms in the intensive care environment (neonatal and adult ICU) in order to increase patient safety and reduce alarm fatigue of the staff.  

In this vulnerable population of preterm infants at the NICU, improving monitoring of maturation of neonates is important to predict patient outcome. Carola is also involved in the development of serious gaming and the development of a simulation model for diabetes.

Academic background

Carola van Pul obtained her PhD on the subject on Diffusion Tensor Imaging in neonates at TU/e. With this technique, it became possible to visualize white matter fiber structures in vivo in the neonatal brain. She also holds an MSc in Applied Physics from Delft University of Technology. Carola did her specialization in medical physics (a medical profession in the Netherlands) at the Maxima Medical Center, Eindhoven, where she has been a clinical physicist since 2006. In 2008, she was involved as a researcher at the University Medical Center Utrecht in a project on Diffusion Tensor Imaging (project) for neonatal brain imaging

In this capacity, Carola is involved in medical equipment procurement processes and safe introduction and application of this equipment, e.g. in the Women-Mother and Child center, with a particular focus on risk analysis for complex medical technology, such as medical alarm systems at a NICU. She regularly contributes to leading journals such as Early Human Development and Interactive Journal of Medical Research.

Carola is actively involved in the Eindhoven MedTech Innovation Center (e/MTIC), a research collaboration between The Catharina Hospital (CH), the Maxima Medical Center (MMC), Kempenhaeghe Epilepsy and Sleep Center (KH), Eindhoven University of Technology (TU/e), and Royal Philips Eindhoven (RPE) in the domains cardiovascular care, perinatal care and sleep care.

Education/Academic qualification

1 Sep 20021 Sep 2006

Eindhoven University of Technology

1 Jul 200029 Nov 2004

Delft University of Technology

1 Sep 199414 May 2000

External positions

Klinisch Fysicus Maxima Medisch Centrum

1 Jul 2006 → …

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Research Output 2003 2020

Automated discomfort detection for premature infants in NICU using time-frequency feature-images and CNNs

Sun, Y., Kommers, D., Tan, T., Wang, W., Long, X., Shan, C., van Pul, C., Aarts, R. M., Andriessen, P. & de With, P. H. N., 2020, SPIE Medical Imaging. SPIE

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

22 Downloads (Pure)

Artifacts in pulse transit time measurements using standard patient monitoring equipment

Bennis, F. C., van Pul, C., van den Bogaart, J. J. L., Andriessen, P., Kramer, B. W. & Delhaas, T., 21 Jun 2019, In : PLoS ONE. 14, 6, 10 p., e0218784.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Patient monitoring
Pulse Wave Analysis
Physiologic Monitoring
Time measurement

Automatic and continuous discomfort detection for premature infants in a NICU using video-based motion analysis

Sun, Y., Kommers, D., Wang, W., Joshi, R., Shan, C., Tan, T., Aarts, R. M., Pul, C. V., Andriessen, P. & With, P. H. N. D., 2019, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Piscataway: Institute of Electrical and Electronics Engineers, p. 5995-5999 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Optical flows
Support vector machines
1 Downloads (Pure)

Beepless: using peripheral interaction in an intensive care seting

Guerra, M. C., Kommers, D., Bakker, S., An, P., van Pul, C. & Andriessen, P., 18 Jun 2019, DIS 2019 - Proceedings of the 2019 ACM Designing Interactive Systems Conference. New York: Association for Computing Machinery, Inc, p. 607-620 14 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Alarm systems
1 Citation (Scopus)
3 Downloads (Pure)

Cardiorespiratory coupling in preterm infants

Joshi, R., Kommers, D., Long, X., Feijs, L., van Huffel, S., van Pul, C. & Andriessen, P., 1 Jan 2019, In : Journal of Applied Physiology. 126, 1, p. 202-213 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Premature Infants
Heart Rate

Student theses

A deeper understanding of RDS and the LISA-procedure: signal analysis and modelling approach

Author: Geurten, L., 28 Feb 2019

Supervisor: Bovendeerd, P. (Supervisor 1), Andriessen, P. (External coach) & van Pul, C. (External coach)

Student thesis: Master

Assessing hypoxic ischemia in the neonatal brain: accuracy of diffusion weighted imaging in MR

Author: van den Tillaart, J., 7 Apr 2004

Supervisor: Wijn, P. (Supervisor 1) & van Pul, C. (Supervisor 2)

Student thesis: Master


Assessing the effects of training in patients with type 2 diabetes Mellitus and co-morbidity using 31P-MRS and NIRS

Author: Kramer, A., 30 Nov 2005

Supervisor: van Pul, C. (Supervisor 1), Prompers, J. (Supervisor 2), Wijn, P. (Supervisor 2) & Nicolaij, K. (Supervisor 2)

Student thesis: Master

Automatic atlas based white matter bundle labeling for neonates

Author: van den Boom, R., 30 Apr 2011

Supervisor: Vilanova Bartroli, A. (Supervisor 1) & van Pul, C. (Supervisor 2)

Student thesis: Master

De plaats van MRI bij de diagnose aortaklepstenose: een vergelijking tussen MRI en echocardiografie

Author: de Jong, N., 30 Jun 2002

Supervisor: Wijn, P. (Supervisor 1) & van Pul, C. (Supervisor 2)

Student thesis: Master