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Personal profile


“As medical physicist I focus on improving the quality, safety and cost-effectiveness of healthcare – by developing and implementing new technology for diagnosis and treatment of patients.”

Research profile

Carola van Pul is an Associate Professor and Chair of Clinical Physics at Eindhoven University of Technology (TU/e). Her fields of expertise concerns general clinical physics - for radiology, nuclear medicine, radiation protection, with a particular specialization in medical technology used for mother-and-child care. 

Next to her clinical tasks as clinical physicist in MMC, Carola is an active researcher. Focus of her research is currently on patient monitoring for (neonatal) intensive care and complex patient monitoring and medical alarm systems using ICT networks. New monitoring techniques are developed for improving diagnosis but also data mining approaches are investigated to reduce the high number of alarms in the intensive care environment (neonatal and adult ICU) in order to increase patient safety and reduce alarm fatigue of the staff.  

In this vulnerable population of preterm infants at the NICU, improving monitoring of maturation of neonates is important to predict patient outcome. Carola is also involved in the development of serious gaming and the development of a simulation model for diabetes.

Academic background

Carola van Pul obtained her PhD on the subject on Diffusion Tensor Imaging in neonates at TU/e. With this technique, it became possible to visualize white matter fiber structures in vivo in the neonatal brain. She also holds an MSc in Applied Physics from Delft University of Technology. Carola did her specialization in medical physics (a medical profession in the Netherlands) at the Maxima Medical Center, Eindhoven, where she has been a clinical physicist since 2006. In 2008, she was involved as a researcher at the University Medical Center Utrecht in a project on Diffusion Tensor Imaging (project) for neonatal brain imaging

In this capacity, Carola is involved in medical equipment procurement processes and safe introduction and application of this equipment, e.g. in the Women-Mother and Child center, with a particular focus on risk analysis for complex medical technology, such as medical alarm systems at a NICU. She regularly contributes to leading journals such as Early Human Development and Interactive Journal of Medical Research.

Carola is actively involved in the Eindhoven MedTech Innovation Center (e/MTIC), a research collaboration between The Catharina Hospital (CH), the Maxima Medical Center (MMC), Kempenhaeghe Epilepsy and Sleep Center (KH), Eindhoven University of Technology (TU/e), and Royal Philips Eindhoven (RPE) in the domains cardiovascular care, perinatal care and sleep care.

Education/Academic qualification

1 Sep 20021 Sep 2006

Eindhoven University of Technology

1 Jul 200029 Nov 2004

Delft University of Technology

1 Sep 199414 May 2000

External positions

Klinisch Fysicus Maxima Medisch Centrum

1 Jul 2006 → …

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Research Output

Automated discomfort detection for premature infants in NICU using time-frequency feature-images and CNNs

Sun, Y., Kommers, D., Tan, T., Wang, W., Long, X., Shan, C., van Pul, C., Aarts, R. M., Andriessen, P. & de With, P. H. N., 2020, SPIE Medical Imaging. SPIE, Vol. 11314. 8 p. 11314

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

  • Predicting neonatal sepsis using features of heart rate variability, respiratory characteristics and ECG-derived estimates of infant motion

    Joshi, R., Kommers, D., Oosterwijk, L., Feijs, L., van Pul, C. & Andriessen, P., Mar 2020, In : IEEE Journal of Biomedical and Health Informatics. 24, 3, p. 681-692 12 p., 8758174.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 1 Downloads (Pure)

    Quality assessment and response to less invasive surfactant administration (LISA) without sedation

    de Kort, E., Kusters, S., Niemarkt, H., van Pul, C., Reiss, I., Simons, S. & Andriessen, P., Jan 2020, In : Pediatric Research. 87, 1, p. 125-130 6 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 1 Citation (Scopus)

    Artifacts in pulse transit time measurements using standard patient monitoring equipment

    Bennis, F. C., van Pul, C., van den Bogaart, J. J. L., Andriessen, P., Kramer, B. W. & Delhaas, T., 21 Jun 2019, In : PLoS ONE. 14, 6, 10 p., e0218784.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 26 Downloads (Pure)

    Automatic and continuous discomfort detection for premature infants in a NICU using video-based motion analysis

    Sun, Y., Kommers, D., Wang, W., Joshi, R., Shan, C., Tan, T., Aarts, R. M., Pul, C. V., Andriessen, P. & With, P. H. N. D., Jul 2019, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Piscataway: Institute of Electrical and Electronics Engineers, p. 5995-5999 5 p. 8857597

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

  • 1 Citation (Scopus)

    Student theses

    A deeper understanding of RDS and the LISA-procedure: signal analysis and modelling approach

    Author: Geurten, L., 28 Feb 2019

    Supervisor: Bovendeerd, P. (Supervisor 1), Andriessen, P. (External coach) & van Pul, C. (External coach)

    Student thesis: Master

    Assessing hypoxic ischemia in the neonatal brain: accuracy of diffusion weighted imaging in MR

    Author: van den Tillaart, J., 7 Apr 2004

    Supervisor: Wijn, P. (Supervisor 1) & van Pul, C. (Supervisor 2)

    Student thesis: Master


    Assessing the effects of training in patients with type 2 diabetes Mellitus and co-morbidity using 31P-MRS and NIRS

    Author: Kramer, A., 30 Nov 2005

    Supervisor: van Pul, C. (Supervisor 1), Prompers, J. (Supervisor 2), Wijn, P. (Supervisor 2) & Nicolaij, K. (Supervisor 2)

    Student thesis: Master

    Automatic atlas based white matter bundle labeling for neonates

    Author: van den Boom, R., 30 Apr 2011

    Supervisor: Vilanova Bartroli, A. (Supervisor 1) & van Pul, C. (Supervisor 2)

    Student thesis: Master

    De plaats van MRI bij de diagnose aortaklepstenose: een vergelijking tussen MRI en echocardiografie

    Author: de Jong, N., 30 Jun 2002

    Supervisor: Wijn, P. (Supervisor 1) & van Pul, C. (Supervisor 2)

    Student thesis: Master