• 473 Citations
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Personal profile


“As medical physicist I focus on improving the quality, safety and cost-effectiveness of healthcare – by developing and implementing new technology for diagnosis and treatment of patients.”

Research profile

Carola van Pul is an Associate Professor and Chair of Clinical Physics at Eindhoven University of Technology (TU/e). Her fields of expertise concerns general clinical physics - for radiology, nuclear medicine, radiation protection, with a particular specialization in medical technology used for mother-and-child care. 

Next to her clinical tasks as clinical physicist in MMC, Carola is an active researcher. Focus of her research is currently on patient monitoring for (neonatal) intensive care and complex patient monitoring and medical alarm systems using ICT networks. New monitoring techniques are developed for improving diagnosis but also data mining approaches are investigated to reduce the high number of alarms in the intensive care environment (neonatal and adult ICU) in order to increase patient safety and reduce alarm fatigue of the staff.  

In this vulnerable population of preterm infants at the NICU, improving monitoring of maturation of neonates is important to predict patient outcome. Carola is also involved in the development of serious gaming and the development of a simulation model for diabetes.

Academic background

Carola van Pul obtained her PhD on the subject on Diffusion Tensor Imaging in neonates at TU/e. With this technique, it became possible to visualize white matter fiber structures in vivo in the neonatal brain. She also holds an MSc in Applied Physics from Delft University of Technology. Carola did her specialization in medical physics (a medical profession in the Netherlands) at the Maxima Medical Center, Eindhoven, where she has been a clinical physicist since 2006. In 2008, she was involved as a researcher at the University Medical Center Utrecht in a project on Diffusion Tensor Imaging (project) for neonatal brain imaging

In this capacity, Carola is involved in medical equipment procurement processes and safe introduction and application of this equipment, e.g. in the Women-Mother and Child center, with a particular focus on risk analysis for complex medical technology, such as medical alarm systems at a NICU. She regularly contributes to leading journals such as Early Human Development and Interactive Journal of Medical Research.

Carola is actively involved in the Eindhoven MedTech Innovation Center (e/MTIC), a research collaboration between The Catharina Hospital (CH), the Maxima Medical Center (MMC), Kempenhaeghe Epilepsy and Sleep Center (KH), Eindhoven University of Technology (TU/e), and Royal Philips Eindhoven (RPE) in the domains cardiovascular care, perinatal care and sleep care.

Education/Academic qualification

1 Sep 20021 Sep 2006

Eindhoven University of Technology

1 Jul 200029 Nov 2004

Delft University of Technology

1 Sep 199414 May 2000

External positions

Klinisch Fysicus Maxima Medisch Centrum

1 Jul 2006 → …

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Premature Infants Medicine & Life Sciences
Electroencephalography Medicine & Life Sciences
Newborn Infant Medicine & Life Sciences
Diffusion Tensor Imaging Medicine & Life Sciences
Macropodidae Medicine & Life Sciences
Education Medicine & Life Sciences
Internal Capsule Medicine & Life Sciences
Ischemia Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2003 2019

Cardiorespiratory coupling in preterm infants

Joshi, R., Kommers, D., Long, X., Feijs, L., van Huffel, S., van Pul, C. & Andriessen, P., 1 Jan 2019, In : Journal of Applied Physiology. 126, 1, p. 202-213 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Premature Infants
Heart Rate
1 Citation (Scopus)

Changes in autonomic regulation due to Kangaroo care remain unaffected by using a swaddling device

Kommers, D. R., Joshi, R., Pul, C. V., Feijs, L., Bambang Oetomo, S. & Andriessen, P., 1 Feb 2019, In : Acta Paediatrica. 108, 2, p. 258-265

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Heart Rate
Equipment and Supplies
Respiratory Rate

Monitoring the respiratory rate of preterm infants using an ultrathin film sensor embedded in the bedding: a comparative feasibility study

Joshi, R., Bierling, B., Feijs, L., van Pul, C. & Andriessen, P., 3 Apr 2019, In : Physiological Measurement.

Research output: Contribution to journalArticleAcademicpeer-review

Ultrathin films
Feasibility Studies
Respiratory Rate
Premature Infants

A ballistographic approach for continuous and non-obtrusive monitoring of movement in neonates

Joshi, R., Bierling, B., Long, X., Weijers, J., Feijs, L., van Pul, C. & Andriessen, P., 12 Oct 2018, In : IEEE Journal of Translational Engineering in Health and Medicine. 6, p. 10 2700809

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Video recording
Thin films

Does the architectural layout of a NICU affect alarm pressure? A comparative clinical audit of a single-family room and an open bay area NICU using a retrospective study design

Joshi, R., Straaten, H. V., Mortel, H. V. D., Long, X., Andriessen, P. & Pul, C. V., 1 Jun 2018, In : BMJ open. 8, 6, 10 p., e022813

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Clinical Audit
Neonatal Intensive Care Units
Retrospective Studies

Student theses

A deeper understanding of RDS and the LISA-procedure: signal analysis and modelling approach

Author: Geurten, L., 28 Feb 2019

Supervisor: Bovendeerd, P. (Supervisor 1), Andriessen, P. (External person) (External coach) & van Pul, C. (External coach)

Student thesis: Master

Assessing hypoxic ischemia in the neonatal brain: accuracy of diffusion weighted imaging in MR

Author: van den Tillaart, J., 7 Apr 2004

Supervisor: Wijn, P. (Supervisor 1) & van Pul, C. (Supervisor 2)

Student thesis: Master


Assessing the effects of training in patients with type 2 diabetes Mellitus and co-morbidity using 31P-MRS and NIRS

Author: Kramer, A., 30 Nov 2005

Supervisor: van Pul, C. (Supervisor 1), Prompers, J. (Supervisor 2), Wijn, P. (Supervisor 2) & Nicolaij, K. (Supervisor 2)

Student thesis: Master

Automatic atlas based white matter bundle labeling for neonates

Author: van den Boom, R., 30 Apr 2011

Supervisor: Vilanova Bartroli, A. (Supervisor 1) & van Pul, C. (Supervisor 2)

Student thesis: Master

De plaats van MRI bij de diagnose aortaklepstenose: een vergelijking tussen MRI en echocardiografie

Author: de Jong, N., 30 Jun 2002

Supervisor: Wijn, P. (Supervisor 1) & van Pul, C. (Supervisor 2)

Student thesis: Master