Personal profile
Quote
Single molecule biosensors are a great benefit for society. They can be applied for monitoring and control in healthcare, food, and the environment.
Research profile
Arthur de Jong is an assistant professor in the research group for Molecular Biosensing for Medical Diagnostics, a joint group of the TU/e departments of Applied Physics and Biomedical Engineering. He develops approaches for single-molecule sensing with the aim to study individual biomolecules in complex environments. He aims to develop next-generation biosensing principles that enable continuous patient monitoring. In his research he combines small colloidal particles with molecular constructs to engineer single molecule sensors. His current research focusses on
* single molecule techniques;
* colloid and interface functionalization and interactions;
* designing and making non-fouling surfaces; and
* microfluidics and sensor integration technology.
Academic background
Arthur de Jong studied Chemical Engineering at Eindhoven University of Technology (TU/e), where he obtained his MSc degree in 1989. In 1994, he received his PhD from the Schuit Institute of Catalysis and continued his research at TU/e in the field of catalysis and surface science as a postdoc. In 1997, he joined the group Applications of Ion Beams and Accelerators at the TU/e department of Applied Physics, where he was appointed as assistant professor in 2000. He joined the group Molecular Biosensing for Medical Diagnostics in 2005. Arthur de Jong is a core member of the Institute for Complex Molecular Systems at TU/e, where groups from different disciplines (chemistry, physics, biomedical engineering, mathematics) collaborate on multidisciplinary research topics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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Real-time Biomolecular Sensing for Smart Food Industry
Prins, M. W. J. (Project Manager), Vu, C. (Project member), Michielsen, C. M. S. (Project member) & de Jong, A. M. (Project member)
1/05/21 → 21/12/26
Project: Third tier
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Continuous Sensing of Lactate Dehydrogenase with a Competitive Particle-Based Sensor for Monitoring Cell Death
Belina, E., de Jong, A. M. & Prins, M. W. J. (Corresponding author), 22 May 2026, In: ACS Sensors. 11, 5, p. 3763-3771 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Downloads (Pure) -
Continuous monitoring of dsDNA fragments for biomanufacturing: Sensor development and feasibility study
Janssen, S. A. J., de Jong, A. M. & Prins, M. W. J. (Corresponding author), 15 Nov 2025, In: Biosensors and Bioelectronics. 288, 9 p., 117808.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)79 Downloads (Pure) -
Continuous Protein Sensing Using Fast-Dissociating Antibody Fragments in Competition-Based Biosensing by Particle Motion
Michielsen, C. M. S., Lin, Y.-T., Yan, J., de Jong, A. M. & Prins, M. W. J. (Corresponding author), 25 Apr 2025, In: ACS Sensors. 10, 4, p. 2895-2905 11 p., 4c03637.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Link opens in a new tab Citations (Scopus)108 Downloads (Pure) -
How Highly Heterogeneous Sensors with Single-Molecule Resolution can Result in Robust Continuous Monitoring Over Long Time Spans
Vu, C., Yan, J., de Jong, A. M. & Prins, M. W. J. (Corresponding author), 17 Feb 2025, In: Advanced Science. 12, 7, 9 p., 2412181.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Link opens in a new tab Citations (Scopus)74 Downloads (Pure) -
Reversible Sandwich-Based Particle Nanoswitch for Continuous Protein Monitoring at Picomolar Concentrations with Automated Calibration
Michielsen, C. M. S., Yan, J., Bergkamp, M. H., Lin, Y.-T., Haenen, S. R. R., Lubken, R. M., Gräwe, A., Swietlikowska, A., de Jong, A. M. & Prins, M. W. J. (Corresponding author), 15 Dec 2025, In: Angewandte Chemie - International Edition. 64, 51, 11 p., e202517725.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)41 Downloads (Pure)
Courses
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Advanced Computational and Experimental Skills
de Jong, A. M., Langereis, E. & Donders, T. J. M. 1/09/23 → 31/08/26
Course
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Advanced Optical Microscopy
Albertazzi, L., de Jong, A. M., Zijlstra, P., Tielrooij, K.-J., Lavrijsen, R. & Kashkanova, A. 1/09/18 → 31/08/26
Course
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Design and Automation in Experiments
de Jong, A. M., Nijdam, S., Linssen, M. D. M. E. & Roog, W. J. 1/09/23 → 31/08/26
Course
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Thesis
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De bouw van een TDS-opstelling
de Jong, A. M. (Author) & Janssens, T. V. W. (Author), 1989Student thesis: Master
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