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Research profile

Albert Aldenkamp is Part-time Professor in the Department of Electrical Engineering of Eindhoven University of Technology (TU/e). Within the Signal Processing System group, Aldenkamp focuses on brain MR-imaging and detailed processing of MR signals, specifically to understand processes of neurodegeneration.

This is the next evolution of his research background in epilepsy and its cognitive comorbidities. Aldenkamp is an internationally renowned epilepsy researcher, who has held professorships at multiple universities and is currently still a professor at Maastricht University Medical Center (MUMC) and a key research, strategy and management figure at Kempenhaeghe Epilepsy Centre.

In a collaborative multi-year project of TU/e, MUMC and Kempenhaeghe, Aldenkamp leads a multimodal MRI program that connects technological and clinical expertise. In his capacity as professor at TU/e, Aldenkamp focuses on using signal analysis for research into causality, neurodegeneration, neuromodulation and neuropharmacology.

Until 2012, Aldenkamp was Editor-in-Chief of the European Journal of Epileptology. He is currently a member of the Editorial Boards of medical journals such as: Epilepsy and Behaviour, Acta Neurologica Scandinavica and Clinical Neurology and neurosurgery, a member of the International Advisory Board of two Pharmaceutical companies, and a member of the Dutch advisory Board for two pharmaceutical industries.

Academic background

Albert Aldenkamp obtained his PhD on Cognition and Epilepsy from Groningen University in 1984 and has held several professorates. He was appointed professor in Leiden in 1991 and in Amsterdam in 1998. Since 2002, he is Chair of Epileptology and Neurocognition of Maastricht University Medical Centre and Head of the Epilepsy Imaging Research Group of the Research School Mental Health and Neurosciences (MHeNS) of the University of Maastricht. In addition, he holds several roles at Kempenhaeghe Epilepsy Centre, such as Head of the Department of Behavioral Research. In 2013, he was appointed part-time professor of Cognition and Imaging in Epilepsy at Eindhoven University of Technology.


“In epilepsy, comorbidity in the form of the cognitive effects of the disease cause around half of the disease burden. Cognition and epilepsy are intertwined to a remarkable degree.”

External positions

Visiting Professor, Ghent University Hospital

1 Jan 2009 → …

Full Professor, Maastricht University Medical Center

1 Jan 2001 → …

Fingerprint Dive into the research topics where A.P. (Bert) Aldenkamp is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Epilepsy Medicine & Life Sciences
Seizures Medicine & Life Sciences
Ketogenic Diet Medicine & Life Sciences
Rolandic Epilepsy Medicine & Life Sciences
Anticonvulsants Medicine & Life Sciences
Cognition Medicine & Life Sciences
Brain Medicine & Life Sciences
Magnetic Resonance Imaging Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1999 2019

1 Citation (Scopus)

Accelerated cognitive ageing in epilepsy: A neuropsychological evaluation of cognitive deterioration

Breuer, L. E. M., Bernas, A., Boon, P., Besseling, R. M. H., Carrette, E. C. B., de Louw, A. & Aldenkamp, A. P., May 2019, In : Archives of Clinical Neuropsychology. 34, 3, p. 301-309 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cognitive Aging
1 Citation (Scopus)
30 Downloads (Pure)

A new analysis approach for T2 relaxometry myelin water quantification: Orthogonal Matching Pursuit

Drenthen, G. S., Backes, W. H., Aldenkamp, A. P., Op ’t Veld, G. J. & Jansen, J. F. A., May 2019, In : Magnetic Resonance in Medicine. 81, 5, p. 3292-3303 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Myelin Sheath
Least-Squares Analysis
Nervous System Diseases
1 Citation (Scopus)
17 Downloads (Pure)

Applicability and reproducibility of 2D multi-slice GRASE myelin water fraction with varying acquisition acceleration

Drenthen, G. S., Backes, W. H., Aldenkamp, A. P. & Jansen, J. F. A., 15 Jul 2019, In : Neuroimage. 195, p. 333-339 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Myelin Sheath
Demyelinating Diseases
Nervous System Diseases

Cognition and quality of life in patients with poststroke epilepsy: a case–control study

van Tuijl, J. H., van Raak, E. P. M., van Oostenbrugge, R. J., Aldenkamp, A. P. & Rouhl, R. P. W., 30 Aug 2019, In : Epilepsy and Behavior. 106444.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Quality of Life
National Institutes of Health (U.S.)
9 Downloads (Pure)

Cognitive development in absence epilepsy during long-term follow-up

Fonseca Wald, E. L. A., Klinkenberg, S., Voncken, T. P. C., Ebus, S. C. M., Aldenkamp, A. P., Vles, J. S. H., Vermeulen, R. J., Hendriksen, J. G. M. & Debeij-van Hall, M. H. J. A., Nov 2019, In : Child Neuropsychology. 25, 8, p. 1003-1021 19 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Absence Epilepsy
Reaction Time


Cognitive neuroscience

1/09/14 → …


Student theses

Brain blood perfusion and white matter integrity in accelerated cognitive ageing patiens with epilepsy

Author: Stevens, J., 31 Oct 2019

Supervisor: Breeuwer, M. (Supervisor 1), Pluim, J. (Supervisor 2), Aldenkamp, A. (Supervisor 2), Zinger, S. (Supervisor 2), Mestrom, R. (Supervisor 2) & Bernas, A. (Supervisor 2)

Student thesis: Master

Effects of TMS on functional and structural brain networks in major depression disorder patients

Author: Franklin, S., 22 Dec 2016

Supervisor: Meusen - Klooster, D. (Supervisor 1), Besseling, R. (Supervisor 2), Nicolaij, K. (Supervisor 2) & Aldenkamp, A. (Supervisor 2)

Student thesis: Master

Functional MRI analysis: salience network and neurodynamics in accelerated cognitive ageing

Author: Gunther, M., 25 Oct 2018

Supervisor: Aldenkamp, A. (Supervisor 1), Bernas, A. (Supervisor 2) & Zinger, S. (Supervisor 2)

Student thesis: Master

Improved method of segmentation of hippocampus using 7T MRI brain volume based on multi-atlas label fusion

Author: Jiang, S., 30 Aug 2016

Supervisor: Aldenkamp, A. (Supervisor 1), Jasinschi, R. (External person) (External coach) & Veerman, J. (External person) (External coach)

Student thesis: Master

Study of alterations in the brain for two neurological disorders, based on magnetic resonance spectroscopy (MRS) and imaging (MRI)

Author: Drenthen, G., 31 Aug 2015

Supervisor: Aldenkamp, A. (Supervisor 1), Tijhuis, A. (Supervisor 2), Zinger, S. (Supervisor 2) & Jansen, J. (External coach)

Student thesis: Master