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Research Output

2020

Differential leaflet remodeling of bone marrow cell pre-seeded versus nonseeded bioresorbable transcatheter pulmonary valve replacements

Fioretta, E., Lintas, V., Mallone, A., Motta, S. E., von Boehmer, L., Dijkman, P. E., Cesarovic, N., Caliskan, E., Rodriguez Cetina Biefer, H., Lipiski, M., Sauer, M., Putti, M., Janssen, H. M., Söntjens, S. H. M., Smits, A. I. P. M., Bouten, C. V. C., Emmert, M. Y. & Hoerstrup, S. P., 1 Jan 2020, In : JACC: Basic to Translational Science. 5, 1, p. 15-31 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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2 Citations (Scopus)
9 Downloads (Pure)
Open Access
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2 Citations (Scopus)
19 Downloads (Pure)
Open Access

Layer-specific cell differentiation in bi-layered vascular grafts under flow perfusion

Pennings, I., van Haaften, E. E., Juengst, T., Bulsink, J. A., Rosenberg, A. J. W. P., Groll, J., Bouten, C. V. C., Kurniawan, N. A., Smits, A. I. P. M. & Gawlitta, D., 1 Jan 2020, In : Biofabrication. 12, 1, 13 p., 015009.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
5 Downloads (Pure)
2019

Cyclic strain affects macrophage cytokine secretion and ECM turnover in electrospun scaffolds

Bonito, V., de Kort, B., Bouten, C. & Smits, A. I. P. M., 1 Sep 2019, In : Tissue engineering. Part A. 25, 17-18, p. 1310-1325 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)
11 Downloads (Pure)

Design of an affinity based cytokine release system to temporally control macrophage behavior

Lurier, E., Smits, A., Bouten, C. V. C. & Spiller, K. L., 1 Jan 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Muttenz: Swiss Society for Biomaterials, p. 49 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

6 Downloads (Pure)

Elastin in vascular grafts

Wang, R., de Kort, B., Smits, A. & Weiss, A., 27 Aug 2019, Tissue-Engineered Vascular Grafts. Walpoth, B., Bergmeister, H., Bowlin, G., Kong, D., Rotmans, J. & Zilla, P. (eds.). Cham: Springer Nature Switzerland AG, p. 1-32 (Reference Series in Biomedical Engineering ).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Downloads (Pure)

Macrophage-driven biomaterial degradation depends on scaffold microarchitecture

Wissing, T. B., Bonito, V., van Haaften, E. E., van Doeselaar, M., Brugmans, M. M. C. P., Janssen, H. M., Bouten, C. V. C. & Smits, A. I. P. M., 26 Apr 2019, In : Frontiers in Bioengineering and Biotechnology. 7, APR, 20 p., 87.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Citations (Scopus)
81 Downloads (Pure)
3 Citations (Scopus)
9 Downloads (Pure)

Tissue-engineered heart valves

Mela, P., Hinderer, S., Kandail, H. S., Bouten, C. & Smits, A., Sep 2019, Principles of Heart Valve Engineering. Kheradvar, A. (ed.). Amsterdam: Elsevier, p. 123-176 54 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

3 Downloads (Pure)

Vascular tissue engineering: pathological considerations, mechanisms, and translational implications

Schoen, F., Fioretta, E. S., Mallone, A., Smits, A. I. P. M., Klouda, E. L. L. & Bouten, C. V. C., 26 Oct 2019, Tissue-Engineered Vascular Grafts. Walpoth, B., Bergmeister, H., Bowlin, G., Kong, D., Rotmans, J. & Zilla, P. (eds.). Cham, Switzerland: Springer Nature Switzerland AG, p. 1-41 (Reference serie in Biomedical Engineering).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2 Downloads (Pure)
2018
Open Access
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10 Citations (Scopus)
93 Downloads (Pure)

Decoupling the effect of shear stress and stretch on tissue growth and remodeling in a vascular graft

van Haaften, E. E., Wissing, T. B., Rutten, M. C. M., Bulsink, J. A., Gashi, K., van Kelle, M. A. J., Smits, A. I. P. M., Bouten, C. V. C. & Kurniawan, N. A., 1 Jul 2018, In : Tissue Engineering. Part C: Methods. 24, 7, p. 418-429 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
9 Downloads (Pure)

Host response and neo-tissue development during resorption of a fast degrading supramolecular electrospun arterial scaffold

Duijvelshoff, R., van Engeland, N. C. A., Gabriels, K. M. R., Söntjens, S. H. M., Smits, A. I. P. M., Dankers, P. Y. W. & Bouten, C. V. C., Sep 2018, In : Bioengineering. 5, 3, 16 p., 61.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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4 Citations (Scopus)
45 Downloads (Pure)

Modulation of macrophage phenotype and protein secretion via heparin-IL-4 functionalized supramolecular elastomers

Bonito, V., Smits, A. I. P. M., Goor, O. J. G. M., Ippel, B. D., Driessen-Mol, A., Münker, T. J. A. G., Bosman, A. W., Mes, T., Dankers, P. Y. W. & Bouten, C. V. C., 15 Apr 2018, In : Acta Biomaterialia. 71, p. 247-260 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
2 Downloads (Pure)

Sheep-specific immunohistochemical panel for the evaluation of regenerative and inflammatory processes in tissue-engineered heart valves

Dekker, S., van Geemen, D., van den Bogaerdt, A. J., Driessen-Mol, A., Aikawa, E. & Smits, A. I. P. M., 15 Aug 2018, In : Frontiers in Cardiovascular Medicine. 5, 19 p., 105.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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5 Citations (Scopus)
41 Downloads (Pure)
12 Citations (Scopus)
6 Downloads (Pure)
2017

Biomaterial-driven in situ cardiovascular tissue engineering : a multi-disciplinary perspective

Wissing, T. B., Bonito, V., Bouten, C. V. C. & Smits, A. I. P. M., 16 Jun 2017, In : npj Regenerative Medicine. 2, 1, p. 18-19

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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111 Downloads (Pure)

Ex vivo culture platform for assessment of cartilage repair treatment strategies

Schwab, A., Meeuwsen, A. B. F., Ehlicke, F., Hansmann, J., Mulder, L., Smits, A. I. P. M., Walles, H. & Kock, L. M., 1 Apr 2017, In : ALTEX. 34, 2, p. 267-277 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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7 Citations (Scopus)
162 Downloads (Pure)

In situ heart valve tissue engineering using a bioresorbable elastomeric implant - From material design to 12 months follow-up in sheep

Kluin, J., Talacua, H., Smits, A. I. P. M., Emmert, M. Y., Brugmans, M. C. P., Fioretta, E. S., Dijkman, P. E., Söntjens, S. H. M., Duijvelshoff, R., Dekker, S., Janssen-van den Broek, M. W. J. T., Lintas, V., Vink, A., Hoerstrup, S. P., Janssen, H. M., Dankers, P. Y. W., Baaijens, F. P. T. & Bouten, C. V. C., 1 May 2017, In : Biomaterials. 125, p. 101-117 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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84 Citations (Scopus)
176 Downloads (Pure)
2016

Development of non-cell adhesive vascular grafts using supramolecular building blocks

van Almen, G., Talacua, H., Ippel, B. D., Mollet, B., Ramaekers, M., Simonet, M., Smits, A. I. P. M., Bouten, C. V. C., Kluin, J. & Dankers, P. Y. W., 2016, In : Macromolecular Bioscience. 16, 3, p. 350-362

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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21 Citations (Scopus)
210 Downloads (Pure)

Early in-situ cellularization of a supramolecular vascular graft is modified by synthetic stromal cell-derived factor-1α derived peptides

Muylaert, D. E. P., van Almen, G. C., Talacua, H., Fledderus, J., Kluin, J., van Dongen, J. L. J., Hendrikse, S., Sijbesma, E., Bosman, A. W. T., Mes, T., Thakkar, S. H., Smits, A. I. P. M., Bouten, C. V. C., Dankers, P. Y. W. & Verhaar, M. C., Jan 2016, In : Biomaterials. 76, p. 187-195 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)
13 Downloads (Pure)

In-situ heart valve tissue engineering - Is On-the-Fly preseeding with bone marrow-derived cells required?

Smits, A. I. P. M., Ballotta, V., Driessen-Mol, A., Baaijens, F. P. T. & Bouten, C. V. C., 2016, In : Cardiology. 134, 2, p. 136 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
7 Downloads (Pure)

In situ tissue engineering: seducing the body to regenerate

Smits, A. I. P. M., Bonito, V. & Stoddart, M. J., Sep 2016, In : Tissue engineering. Part A. 22, 17-18, p. 1061-1062 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)
5 Downloads (Pure)
2015

Biomaterial-based in situ tissue engineering of heart valves

Bouten, C. V., Smits, A. I., Talacua, H., Muylaert, D. E., Janssen, H. M., Bosman, A. W., Verhaar, M. C., Dankers, P. Y. W., Driessen - Mol, A., Kluin, J. & Baaijens, F. P. T., 1 Sep 2015, In : Tissue engineering. Part A. 21, p. S6-S6

Research output: Contribution to journalMeeting AbstractAcademic

8 Downloads (Pure)

In situ tissue engineering of functional small-diameter blood vessels by host circulating cells only

Talacua, H., Smits, A., Muylaert, D., van Rijswijk, J. W., Vink, A., Verhaar, M. C., Driessen - Mol, A., van Herwerden, L. A., Bouten, C. V. C., Kluin, J. & Baaijens, F. P. T., Oct 2015, In : Tissue engineering. Part A. 21, 19-20, p. 2583-2594 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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47 Citations (Scopus)
216 Downloads (Pure)
2014

Differential response of endothelial and endothelial colony forming cells on electrospun scaffolds with distinct microfiber diameters

Fioretta, E. S., Simonet, M., Smits, A. I. P. M., Baaijens, F. P. T. & Bouten, C. V. C., 2014, In : Biomacromolecules. 15, 3, p. 821-829 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

27 Citations (Scopus)
4 Downloads (Pure)

Modulating the immune response for in situ cardiovascular tissue engineering

Smits, A. I. P. M., 2014, Eindhoven: Technische Universiteit Eindhoven. 241 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
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747 Downloads (Pure)

Shear flow affects selective monocyte recruitment into MCP-1-loaded scaffolds

Smits, A. I. P. M., Ballotta, V., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2014, In : Journal of Cellular and Molecular Medicine. 18, 11, p. 2176-2188 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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17 Citations (Scopus)
84 Downloads (Pure)

Synergistic protein secretion by mesenchymal stromal cells seeded in 3D scaffolds and circulating leukocytes in physiological flow

Ballotta, V., Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2014, In : Biomaterials. 35, 33, p. 9100-9113 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)
3 Downloads (Pure)
2013

The immune response in In Situ tissue engineering of aortic heart valves

van Loon, S. L. M., Smits, A. I. P. M., Baaijens, F. P. T. & Bouten, C. V. C., 12 Jun 2013, Calcific Aortic Valve Disease. Aikawa, E. (ed.). InTech, p. 207-245

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

File
121 Downloads (Pure)

Then and now: hypes and hopes of regenerative medicine

Slingerland, A. S., Smits, A. & Bouten, C., Mar 2013, In : Trends in Biotechnology. 31, 3, p. 121-123 3 p.

Research output: Contribution to journalArticleAcademic

3 Citations (Scopus)
2012
11 Citations (Scopus)
4 Downloads (Pure)

In situ arterial regeneration in a humanized rat model

Smits, A. I. P. M., Talacua, H., Muylaert, D. E. P., Van Rijswijk, J. W., Vink, A., Driessen - Mol, A., Bouten, C. V. C., Kluin, J. & Baaijens, F. P. T., 2012.

Research output: Contribution to conferencePosterAcademic

2 Downloads (Pure)
7 Downloads (Pure)

Modulating the inflammatory response for in situ tissue engineering – the role of MCP-1

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2012, 5th Biennial Meeting on Heart Valve Biology and Tissue Engineering. Mykonos, Greece

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

5 Downloads (Pure)
2011

A novel bioreactor for the systematic development of functional 3D scaffolds for in-situ cardiovascular tissue engineering

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2011, Proceedings of TERMIS EU 2011 Annual Meeting ( Tissue Engineering & Regenerative Medicine International Society). Granada, Spain, p. 185-186

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

2 Downloads (Pure)

A novel test bed for 3D cell recruitment under hemodynamic conditions

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2011, 3rd Dutch Conference on Biomedical Engineering, 20-24 January 2011, Egmond aan Zee, The Netherlands.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Modulating the inflammatory response - The role of Monocyte Chemotactant Protein-1

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2011.

Research output: Contribution to conferencePosterAcademic

Open Access
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32 Downloads (Pure)
2010

A novel test bed for 3D cell recruitment under hemodynamic conditions

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2010.

Research output: Contribution to conferencePosterAcademic

4 Downloads (Pure)
2009

A high-throughput model system to study in situ cell recruitment

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2009.

Research output: Contribution to conferencePosterAcademic

1 Downloads (Pure)

A one-step approach for in situ cardiovascular tissue regeneration

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2009.

Research output: Contribution to conferencePosterAcademic

4 Downloads (Pure)

Tissue engineering of heart valves: advances and current challenges

Driessen - Mol, A., Smits, A. I. P. M., Bouten, C. V. C. & Baaijens, F. P. T., 2009, In : Expert Review Medical Devices. 6, 3, p. 259-275

Research output: Contribution to journalArticleAcademicpeer-review

101 Citations (Scopus)
4 Downloads (Pure)
2008

A one-step approach for in situ cardiovascular tissue engineering

Smits, A. I. P. M., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2008.

Research output: Contribution to conferencePosterAcademic

Open Access
File
69 Downloads (Pure)