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Biomineralization, the formation of mineral by living organisms, involves ancient strategies to produce materials with advanced functions. I want to know how these fascinating materials are made. 

Research profile

Anat Akiva is a Marie Curie fellow at the Laboratory of Materials and Interface Chemistry in the Eindhoven University of Technology (TU/e). Her primary interest is in the field of biomineralization, aiming to understand the processes of hard tissue formation. With her team, Anat studies the molecular mechanisms of bone formation and collagen mineralization. Her research aims at the fundamental understanding of mineralization processes which have essential implications in regenerative medicine. Her most recent activities also include the study of pathological mineralization in bone-related diseases such as osteogenesis imperfecta (brittle bone disease) and atherosclerosis (blood vessel calcification) 

Academic background

Anat received her B.Sc., and M.Sc. degree (cum laude) in Chemistry from the Technion – Israel Institute of Technology. Her major was in physical chemistry and solid-state NMR. She was first introduced to the world of biomineralization during her master degree, and she continued in this field as a Ph.D. student in the biomineralization group of Prof Lia Addadi and Prof Steve Weiner from the Weizmann Institute of Science, Israel. In her Ph.D. work Anat investigated the process of bone mineralization in vivo using the zebrafish and chicken embryo as animal models. She mastered advanced imaging and spectroscopy techniques such as in vivo fluorescent confocal imaging, cryo-(FIB)-SEM, Raman and µ-spot X-ray spectroscopy.
In October 2016 she joined the laboratory of Materials and Interfaces Chemistry to establish a new research line on Biological Materials Chemistry.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Minerals Medicine & Life Sciences
Calcium Carbonate Medicine & Life Sciences
Zebrafish Medicine & Life Sciences
Bone and Bones Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences
calcium carbonates Physics & Astronomy
Larva Medicine & Life Sciences
Physiologic Calcification Medicine & Life Sciences

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Research Output 2011 2019

  • 189 Citations
  • 10 Article
  • 1 Letter

Intercellular pathways from the vasculature to the forming bone in the zebrafish larval caudal fin: possible role in bone formation

Akiva, A., Nelkenbaum, O., Schertel, A., Yaniv, K., Weiner, S. & Addadi, L., 1 Jan 2019, In : Journal of Structural Biology.

Research output: Contribution to journalArticleAcademicpeer-review

Zebrafish
Osteogenesis
Extracellular Space
Ions
Bone and Bones
15 Citations (Scopus)

Cryo-FIB-SEM serial milling and block face imaging: large volume structural analysis of biological tissues preserved close to their native state

Vidavsky, N., Akiva, A., Kaplan-Ashiri, I., Rechav, K., Addadi, L., Weiner, S. & Schertel, A., 1 Dec 2016, In : Journal of Structural Biology. 196, 3, p. 487-495 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Zebrafish
Minerals
Tail
Electrons
Nuclear Pore
38 Citations (Scopus)

On the pathway of mineral deposition in larval zebrafish caudal fin bone

Akiva, A., Malkinson, G., Masic, A., Kerschnitzki, M., Bennet, M., Fratzl, P., Addadi, L., Weiner, S. & Yaniv, K., 1 Jun 2015, In : Bone. 75, p. 192-200 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Mineral formation in the Larval Zebrafish tail bone occurs via an acidic disordered calcium phosphate phase

Akiva, A., Kerschnitzki, M., Pinkas, I., Wagermaier, W., Yaniv, K., Fratzl, P., Addadi, L. & Weiner, S., 2 Nov 2016, In : Journal of the American Chemical Society. 138, 43, p. 14481-14487 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Calcium phosphate
Zebrafish
Raman Spectrum Analysis
Minerals
Tail
4 Citations (Scopus)

Minerals in the pre-settled coral Stylophora pistillata crystallize via protein and ion changes

Akiva, A., Neder, M., Kahil, K., Gavriel, R., Pinkas, I., Goobes, G. & Mass, T., 1 Dec 2018, In : Nature Communications. 9, 1, 1880

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
aragonite
Anthozoa
Calcium Carbonate
musculoskeletal system
Biomineralization

Prizes

Lev Margulis national Prize for outstanding research in microscopy

Anat Akiva (Recipient), 2015

Recognition: OtherCareer, activity or publication related prizes (lifetime, best paper, poster etc.)Scientific

Marie Skłodowska-Curie Postdoctoral individual Fellowship (IF)

Anat Akiva (Recipient), 2018

Recognition: OtherScholarshipsScientific

Courses