• Department of Biomedical Engineering Eindhoven University of Technology, P.O. Box 513

    5600 MB Eindhoven

    Netherlands

  • Eindhoven University of Technology, Building 15, Gemini-South (room 4.115) Groene Loper

    5612 AZ Eindhoven

    Netherlands

Research Output 1981 2019

2019
4 Downloads (Pure)

A computational model to predict cell traction-mediated prestretch in the mitral valve

van Kelle, M. A. J., Rausch, M. K., Kuhl, E. & Loerakker, S., 18 Nov 2019, In : Computer Methods in Biomechanics and Biomedical Engineering. 22, 15, p. 1174-1185 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tissue
Actins
Structural properties
Anisotropy
Fibers
3 Citations (Scopus)
6 Downloads (Pure)

Analysis of chemical exchange saturation transfer contributions from brain metabolites to the Z-spectra at various field strengths and pH

Khlebnikov, V., van der Kemp, W. J. M., Hoogduin, H., Klomp, D. W. J. & Prompers, J. J., 31 Jan 2019, In : Scientific Reports. 9, 1, 11 p., 1089.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
5 Downloads (Pure)

A stirring system using suspended magnetically-actuated pillars for controlled cell clustering

Saberi, A., Zhang, S., van den Bersselaar, C., Kandail, H., den Toonder, J. M. J. & Kurniawan, N. A., 14 Feb 2019, In : Soft Matter. 15, 6, p. 1435-1443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
stirring
Magnetic scales
Colloids
Research laboratories
cells
5 Downloads (Pure)
Open Access
File
Biocompatible Materials
Pyrimidinones
Proteins
Notch1 Receptor
Click Chemistry
4 Downloads (Pure)

Biomechanics and modeling of tissue-engineered heart valves

Ristori, T., van Kelle, A. J. M., Baaijens, F. & Loerakker, S., 9 Apr 2019, Advances in heart valve biomechanics: valvular physiology, mechanobiology, and bioengineering. Sacks, M. & Liao, J. (eds.). Cham: Springer, p. 413-446 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Biomechanics
Tissue engineering
Tissue
Collagen
Heart valve prostheses
6 Downloads (Pure)

Cell-perceived substrate curvature dynamically coordinates the direction, speed, and persistence of stromal cell migration

Werner, M., Petersen, A., Kurniawan, N. & Bouten, C., 5 Sep 2019, In : Advanced Biosystems. 3, 10, 11 p., 1900080.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Stromal Cells
Cell Movement
Mesenchymal Stromal Cells
Bone
Biocompatible Materials
Open Access
antifouling
Biocompatible Materials
Biomaterials
Peptides
peptides
1 Citation (Scopus)

Cyclic strain affects macrophage cytokine secretion and ECM turnover in electrospun scaffolds

Bonito, V., de Kort, B., Bouten, C. & Smits, A. I. P. M., 1 Sep 2019, In : Tissue engineering. Part A. 25, 17-18, p. 1310-1325 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Military electronic countermeasures
Macrophages
Scaffolds (biology)
Cytokines
Tissue Engineering

Decoding the PTM-switchboard of Notch

Antfolk, D., Antila, C., Kemppainen, K., Landor, S. K. J. & Sahlgren, C., 1 Dec 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 12, 21 p., 118507.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Post Translational Protein Processing
Nimodipine
Translational Medical Research
Glycosylation
Half-Life
2 Downloads (Pure)

Design of an affinity based cytokine release system to temporally control macrophage behavior

Lurier, E., Smits, A., Bouten, C. V. C. & Spiller, K. L., 1 Jan 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Muttenz: Swiss Society for Biomaterials, p. 49 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Behavior Control
Macrophages
Biotin
Streptavidin
Cytokines
1 Downloads (Pure)

Elastin in vascular grafts

Wang, R., de Kort, B., Smits, A. & Weiss, A., 27 Aug 2019, Tissue-Engineered Vascular Grafts. Walpoth, B., Bergmeister, H., Bowlin, G., Kong, D., Rotmans, J. & Zilla, P. (eds.). Cham: Springer Nature Switzerland AG, p. 1-32 (Reference Series in Biomedical Engineering ).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Elastin
Blood Vessels
Transplants
Extracellular Matrix
Cardiovascular Diseases
14 Downloads (Pure)

Engineered bioactive supramolecular materials based on ureido-pyrimidinones

Putti, M., 18 Jun 2019, Eindhoven: Technische Universiteit Eindhoven. 159 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

8 Downloads (Pure)

Engineered cardiac microenvironments based on supramolecular biomaterials

Spaans, S., 13 Mar 2019, Eindhoven: Technische Universiteit Eindhoven. 175 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Biocompatible Materials
2 Citations (Scopus)
21 Downloads (Pure)

Entropic forces drive cellular contact guidance

Buskermolen, A. B. C., Suresh, H., Shishvan, S. S., Vigliotti, A., DeSimone, A., Kurniawan, N. A., Bouten, C. V. C. & Deshpande, V. S., 21 May 2019, In : Biophysical Journal. 116, 10, p. 1994-2008 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Stress Fibers
Entropy
Cell Size
Cell Nucleus Shape
Cell Nucleus Size
172 Downloads (Pure)

Evaluating aetiological processes for monitoring and detection of deep tissue injury

Traa, W. A., 19 Feb 2019, Eindhoven: Technische Universiteit Eindhoven. 140 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
File
1 Downloads (Pure)

Functional peptide presentation on different hydrogen bonding biomaterials using supramolecular additives

van Gaal, R. C., Buskermolen, A. B. C., Ippel, B. D., Fransen, P-P. K. H., Zaccaria, S., Bouten, C. V. C. & Dankers, P. Y. W., Dec 2019, In : Biomaterials. 224, 9 p., 119466.

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Hydrogen Bonding
Biomaterials
Peptides
Hydrogen bonds
1 Downloads (Pure)

Functional supramolecular additives

Ippel, B. D., 24 Sep 2019, Eindhoven: Technische Universiteit Eindhoven. 161 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
Macrophages
Hemodynamics
Biocompatible Materials
Tissue engineering
Biomaterials
2 Downloads (Pure)

Image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues

van Haaften, E. E., van Turnhout, M. C. & Kurniawan, N. A., 25 Mar 2019, In : Soft Matter. 15, 16, p. 3353-3361 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Systematic errors
Biological materials
Stretching
Tissue
Elastomers
1 Citation (Scopus)
25 Downloads (Pure)

Increased cell traction-induced prestress in dynamically cultured microtissues

van Kelle, M. A. J., Khalil, N., Foolen, J., Loerakker, S. & Bouten, C. V. C., 12 Mar 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 11 p., 41.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
18 Downloads (Pure)

Influence of the assembly state on the functionality of a supramolecular jagged1-mimicking peptide additive

Putti, M., Stassen, O. M. J. A., Schotman, M. J. G., Sahlgren, C. M. & Dankers, P. Y. W., 3 May 2019, In : ACS Omega. 4, 5, p. 8178-8187 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pyrimidinones
DSL
Peptides
Polycaprolactone
Self assembly
2 Citations (Scopus)
17 Downloads (Pure)

Investigating the influence of intermittent and continuous mechanical loading on skin through non-invasive sampling of IL-1α

Soetens, J. F. J., Worsley, P. R., Bader, D. L. & Oomens, C. W. J., 1 Feb 2019, In : Journal of Tissue Viability. 28, 1, p. 1-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Interleukin-1
Skin
Pressure Ulcer
Sacrum
Sebum
6 Downloads (Pure)

In vivo and in vitro approaches reveal novel insight into the ability of epicardium-derived cells to create their own extracellular environment

Bax, N. A. M., Duim, S. N., Kruithof, B. P. T., Smits, A. M., Bouten, C. V. C. & Goumans, M. J., 19 Jun 2019, In : Frontiers in Cardiovascular Medicine. 6, 14 p., 81.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Aptitude
Pericardium
Collagen Type I
In Vitro Techniques
Peptide Hydrolases

Layer-specific cell differentiation in bi-layered vascular grafts under flow perfusion

Pennings, I., van Haaften, E. E., Juengst, T., Bulsink, J. A., Rosenberg, A. J. W. P., Groll, J., Bouten, C. V. C., Kurniawan, N. A., Smits, A. I. P. M. & Gawlitta, D., 18 Nov 2019, In : Biofabrication. 12, 1, 13 p., 015009.

Research output: Contribution to journalArticleAcademicpeer-review

Grafts
Blood Vessels
Cell Differentiation
Perfusion
Transplants
2 Downloads (Pure)

Living kidney membranes based on supramolecular materials

van Gaal, R. C., 5 Sep 2019, Eindhoven: Technische Universiteit Eindhoven. 188 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

2 Citations (Scopus)
29 Downloads (Pure)

Macrophage-driven biomaterial degradation depends on scaffold microarchitecture

Wissing, T. B., Bonito, V., van Haaften, E. E., van Doeselaar, M., Brugmans, M. M. C. P., Janssen, H. M., Bouten, C. V. C. & Smits, A. I. P. M., 26 Apr 2019, In : Frontiers in Bioengineering and Biotechnology. 7, APR, 20 p., 87.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Macrophages
Biocompatible Materials
Scaffolds (biology)
Biomaterials
Scaffolds
9 Downloads (Pure)
147 Downloads (Pure)

Mechanical and biochemical response of human skin to diverse loading conditions

Soetens, J. F. J., 18 Jun 2019, Eindhoven: Technische Universiteit Eindhoven. 112 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
File
Skin
6 Downloads (Pure)

Mechanically driven adaptation in engineered cardiovascular tissues

van Kelle, A. J., 31 Jan 2019, Eindhoven: Technische Universiteit Eindhoven. 134 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Heart Valves
Blood Vessels
2 Citations (Scopus)
17 Downloads (Pure)

Myoglobin and troponin concentrations are increased in early stage deep tissue injury

Traa, W. A., Strijkers, G. J., Bader, D. L. & Oomens, C. W. J., 1 Apr 2019, In : Journal of the Mechanical Behavior of Biomedical Materials. 92, p. 50-57 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Troponin
Myoglobin
Blood
Tissue
Biomarkers
9 Downloads (Pure)

On the impact of the mechanical environment in vascular tissue engineering: an in vitro study

van Haaften, E. E., 1 Oct 2019, Eindhoven: Technische Universiteit Eindhoven. 248 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

7 Downloads (Pure)

Preclinical outcomes and translational challenges of material-based in situ vascular tissue engineering

Duijvelshoff, R., 4 Jul 2019, Eindhoven: Technische Universiteit Eindhoven. 201 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

2 Citations (Scopus)
2 Downloads (Pure)

Renal epithelial monolayer formation on monomeric and polymeric catechol functionalized supramolecular biomaterials

van Gaal, R. C., Fedecostante, M., Fransen, P. P. K. H., Masereeuw, R. & Dankers, P. Y. W., Feb 2019, In : Macromolecular Bioscience. 19, 2, 7 p., 1800300.

Research output: Contribution to journalArticleAcademicpeer-review

Pyrimidinones
Biocompatible Materials
Biomaterials
Catechols
Monolayers

Substrate curvature as a regulator of cellular orientation and migration

Werner, M., 19 Sep 2019, Eindhoven: Technische Universiteit Eindhoven. 166 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

2 Citations (Scopus)
5 Downloads (Pure)
Open Access
File
antifouling
Scaffolds
Adhesives
adhesives
casts
2 Downloads (Pure)
polycarbonate
Scaffolds
Blood Vessels
Esters
Polymers

The expression of anaerobic metabolites in sweat and sebum from human skin subjected to intermittent and continuous mechanical loading

Soetens, J. F. J., Worsley, P. R., Herniman, J. M., Langley, G. J., Bader, D. L. & Oomens, C. W. J., Nov 2019, In : Journal of Tissue Viability. 28, 4, p. 186-193 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Sebum
Sweat
Pressure Ulcer
Skin
Pyruvic Acid
6 Downloads (Pure)

The ins and outs of engineering functional tissues and organs: evaluating the in-vitro and in-situ processes

Kurniawan, N., 1 Oct 2019, In : Current Opinion in Organ Transplantation. 24, 5, p. 590-597 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tissue Engineering
Biocompatible Materials
Organ Transplantation
Cell Communication
Regeneration
2 Downloads (Pure)

There is an individual tolerance to mechanical loading in compression induced deep tissue injury

Traa, W. A., van Turnhout, M. C., Nelissen, J. L., Strijkers, G. J., Bader, D. L. & Oomens, C. W. J., 1 Mar 2019, In : Clinical Biomechanics. 63, p. 153-160 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pressure Ulcer
Wounds and Injuries
Edema
Muscles
1 Downloads (Pure)

Tissue-engineered heart valves

Mela, P., Hinderer, S., Kandail, H. S., Bouten, C. & Smits, A., Sep 2019, Principles of Heart Valve Tissue Engineering. Kheradvar, A. (ed.). Amsterdam: Elsevier, p. 124-176 54 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Tissue
Tissue engineering
Forms (concrete)
Hemodynamics
Bioreactors
2 Downloads (Pure)

Traction forces at the cytokinetic ring regulate cell division and polyploidy in the migrating zebrafish epicardium

Uroz, M., Garcia-Puig, A., Tekeli, I., Elosegui-Artola, A., Abenza, J. F., Marín-Llauradó, A., Pujals, S., Conte, V., Albertazzi, L., Roca-Cusachs, P., Raya, Á. & Trepat, X., 3 Jun 2019, In : Nature Materials. 18, 9, p. 1015-1023 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

epicardium
cell division
traction
Cells
adhesion
4 Downloads (Pure)

Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress

van Engeland, N. C. A., Suarez Rodriguez, F., Rivero-Müller, A., Ristori, T., Duran, C. L., Stassen, O. M. J. A., Antfolk, D., Driessen, R. C. H., Ruohonen, S., Ruohonen, S. T., Nuutinen, S., Savontaus, E., Loerakker, S., Bayless, K. J., Sjöqvist, M., Bouten, C. V. C., Eriksson, J. E. & Sahlgren, C. M., 27 Aug 2019, In : Scientific Reports. 9, 1, 14 p., 12415.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Vimentin
Hemodynamics
Vascular Smooth Muscle
Transcriptional Activation
Smooth Muscle Myocytes
1 Citation (Scopus)

What is the potential of tissue-engineered pulmonary valves in children?

Huygens, S. A., Rutten-van Mölken, M. P. M. H., Noruzi, A., Etnel, J. R. G., Corro Ramos, I., Bouten, C. V. C., Kluin, J. & Takkenberg, J. J. M., Jun 2019, In : The Annals of Thoracic Surgery. 107, 6, p. 1845-1853 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pulmonary Valve
Heart Valves
Costs and Cost Analysis
Quality-Adjusted Life Years
Patient Simulation
2018
12 Citations (Scopus)
33 Downloads (Pure)
Open Access
File
Biomimetics
Microfluidics
Endothelial cells
Hemodynamics
Vascular Smooth Muscle
6 Citations (Scopus)
48 Downloads (Pure)

Adaptation of a MR imaging protocol into a real-time clinical biometric ultrasound protocol for persons with spinal cord injury at risk for deep tissue injury: A reliability study

Swaine, J. M., Moe, A., Breidahl, W., Bader, D. L., Oomens, C. W. J., Lester, L., O'Loughlin, E., Santamaria, N. & Stacey, M. C., 1 Feb 2018, In : Journal of Tissue Viability. 27, 1, p. 2-9 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Spinal Cord Injuries
Tendons
Skin
Spinal Cord
Wounds and Injuries
4 Citations (Scopus)
60 Downloads (Pure)

All-printed cell counting chambers with on-chip sample preparation for point-of-care CD4 counting

Wasserberg, D., Zhang, X., Breukers, C., Connell, B. J., Baeten, E., van den Blink, D., Solà Benet, È., Bloem, A. C., Nijhuis, M., Wensing, A. M. J., Terstappen, L. W. M. M. & Beck, M., 15 Oct 2018, In : Biosensors and Bioelectronics. 117, p. 659-668 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Point-of-Care Systems
Antibodies
Microfluidics
Tissue Donors
HIV
4 Citations (Scopus)
63 Downloads (Pure)

A model of human skin under large amplitude oscillatory shear

Soetens, J. F. J., van Vijven, M., Bader, D. L., Peters, G. W. M. & Oomens, C. W. J., 1 Oct 2018, In : Journal of the Mechanical Behavior of Biomedical Materials. 86, p. 423-432 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Skin
Constitutive models
Shear thinning
Parameter estimation
Shear deformation
6 Citations (Scopus)

An advanced magnetic resonance imaging perspective on the etiology of deep tissue injury

Nelissen, J. L., Traa, W. A., de Boer, H. H., de Graaf, L., Mazzoli, V., Savci-Heijink, C. D., Nicolay, K., Froeling, M., Bader, D. L., Nederveen, A. J., Oomens, C. W. J. & Strijkers, G. J., 1 Jun 2018, In : Journal of Applied Physiology. 124, 6, p. 1580-1596 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Magnetic Resonance Imaging
Wounds and Injuries
Muscles
Edema
Angiography
2 Citations (Scopus)
44 Downloads (Pure)

An automated quantitative analysis of cell, nucleus and focal adhesion morphology

Buskermolen, A. B. C., Kurniawan, N. A. & Bouten, C. V. C., 1 Mar 2018, In : PLoS ONE. 13, 3, 16 p., e0195201.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Focal Adhesions
cell nucleus
Cell Nucleus
Cell Adhesion
adhesion
14 Citations (Scopus)

Angiography versus hemodynamics to predict the natural history of coronary stenoses: Fractional flow reserve versus angiography in multivessel evaluation 2 substudy

Ciccarelli, G., Barbato, E., Toth, G. G., Gahl, B., Xaplanteris, P., Fournier, S., Milkas, A., Bartunek, J., Vanderheyden, M., Pijls, N., Tonino, P., Fearon, W. F., Jüni, P. & De Bruyne, B., 3 Apr 2018, In : Circulation. 137, 14, p. 1475-1485 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Coronary Stenosis
Angiography
Pathologic Constriction
Hemodynamics
Confidence Intervals