• Department of Biomedical Engineering Eindhoven University of Technology, P.O. Box 513

    5600 MB Eindhoven

    Netherlands

  • Eindhoven University of Technology, Building 15, Gemini-South (room 4.115) Groene Loper

    5612 AZ Eindhoven

    Netherlands

Organization profile

Introduction / mission

Our mission is to understand and predict how biophysical factors influence biological tissue damage, repair, growth, and adaptation in order to (re)build soft tissues and prevent mechanically-induced soft tissue degeneration.

Highlighted phrase

From laboratory experiment to a permanent part of the healthcare package: from hype to hope 

Organisational profile

Living tissues show an intriguing, active response to mechanical loading. Not only is the intrinsic mechanical response complicated, the ability of living tissues to adapt to mechanical loading by changing their structure and composition is fascinating. For example, tissue proliferation and differentiation is significantly affected by mechanical loading. A quantitative understanding of these phenomena, through experimentation and numerical modeling, is of crucial importance for many biomedical applications. 

Read this interview with Carlijn Bouten (Slash, okt 2017) 

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1981 2019

A stirring system using suspended magnetically-actuated pillars for controlled cell clustering

Saberi, A., Zhang, S., van den Bersselaar, C., Kandail, H., den Toonder, J. M. J. & Kurniawan, N. A., 1 Jan 2019, In : Soft Matter. 15, 6, p. 1435-1443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

stirring
Magnetic scales
Colloids
Research laboratories
cells

Engineered cardiac microenvironments based on supramolecular biomaterials

Spaans, S., 13 Mar 2019, Eindhoven: Technische Universiteit Eindhoven. 175 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Biocompatible Materials

Evaluating aetiological processes for monitoring and detection of deep tissue injury

Traa, W. A., 19 Feb 2019, Eindhoven: Technische Universiteit Eindhoven. 140 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Open Access
File

Equipment

Bioreactors
Blood Vessels
spinners
heart valves
tissue engineering
high voltages
polymers
mechanical properties
glass
cells

Prizes

Annual BME Research Day Poster Prize

Mathieu van Kelle (Recipient), 8 Apr 2016

Recognition: OtherCareer, activity or publication related prizes (lifetime, best paper, poster etc.)Scientific

Dekker Junior 2014T013

Noortje Bax (Recipient), Mar 2015

Recognition: OtherDiscipline relatedScientific

Stem Cells

Grant Application ASTF 497-2012

Noortje Bax (Recipient), May 2013

Recognition: OtherFellowships & membershipsScientific

Colombia
grant
engineering

Activities 1993 2016

  • 6 Contributed talk
  • 3 Editorial activity

Tissue Engineering Part C: Methods (Journal)

Anthal Smits (Editorial board member)
1 Feb 2016

Activity: Publication peer-review and editorial work typesEditorial activityScientific

International Congress of Cell Biology

Rob Driessen (Speaker)
23 Jul 2016

Activity: Talk or presentation typesContributed talkScientific

Unraveling the mechanisms behind cellular anisotropy sensing

Antonetta B.C. Buskermolen (Speaker)
4 Oct 2016

Activity: Talk or presentation typesContributed talkScientific

Press / Media

PhD dissertation - Public Summary

Valentina Bonito

13/09/18

1 media contribution

Press/Media: Research

Rebuilding tissues inside the human body

Carlijn Bouten

11/09/18

1 item of media coverage

Press/Media: Expert Comment

Home Stretch. Implants and Immune Cells

Valentina Bonito

5/09/18

1 item of media coverage

Press/Media: Public Engagement Activities

Research areas

Cell-Matrix Interactions

Yvon Biemans (Content manager), Lieke van Gorp (Content manager), Amy Broeders (Content manager)

Impact: Research Topic/Theme (at group level)

Cell-Matrix Mechanobiology

Yvon Biemans (Content manager), Lieke van Gorp (Content manager), Amy Broeders (Content manager)

Impact: Research Topic/Theme (at group level)

Cell Signaling in Tissue Formation and Malformation

Yvon Biemans (Content manager), Lieke van Gorp (Content manager), Amy Broeders (Content manager)

Impact: Research Topic/Theme (at group level)

Student theses

A constitutive material model to describe the mechanical behavior of human skin in shear, tensile and indentation tests

Author: Rooijakkers, T., 31 Aug 2017

Supervisor: Oomens, C. (Supervisor 1), Loerakker, S. (Supervisor 2), Lopata, R. (Supervisor 2) & Soetens, J. (Supervisor 2)

Student thesis: Master

An in-silico imaging system based on k-Wave for multi-perspective ultrasound imaging of abdominal aortic aneurysms

Author: Nooijens, S., 31 Jan 2019

Supervisor: van de Vosse, F. (Supervisor 1), Lopata, R. (Supervisor 2), Oomens, C. (Supervisor 2), Petterson, N. (Supervisor 2) & Bouwman, R. (Supervisor 2)

Student thesis: Master

Design of a DNA-based tension probe for the quantification of cellular traction forces at a molecular level

Author: van der Putten, C., 25 Jan 2018

Supervisor: Kurniawan, N. (Supervisor 1), de Greef, T. (Supervisor 2) & Bouten, C. (Supervisor 2)

Student thesis: Master