Content available in repository
Content available in repository
Groene Loper, Building 14, Helix (room STO 3.39) , Secretary Tanja Vermaas - Verhaag
5612 AP Eindhoven
Netherlands
P.O. Box 513, Department of Biomedical Engineering
5600 MB Eindhoven
Netherlands
At the protein engineering group we develop new proteins for applications in therapy and diagnosis, while critically testing our understanding of protein function.
Beyond the already impressive functional diversity of natural proteins
Our group operates at the interface of chemical biology and synthetic biology. Combining protein engineering and DNA nanotechnology, we develop intelligent biomolecular sensors and switches for applications in intracellular imaging, optogenetics, point-of-care diagnostics and antibody-based therapies. An important research theme is to develop generic engineering concepts for the development of protein-based switches, which include fluorescent sensors for intracellular imaging of metal ions, photo-switchable proteins, and protein-based sensors for antibody detection and actuation. We have an active policy of sharing our protein building blocks by depositing our plasmids to AddGene and promote their use by writing dedicated protocols and tutorial reviews. In education, our main goal is to train bachelor, masters and PhD students to become creative biomolecular engineers and independent critical scientists.
Person: Prom. : doctoral candidate (PhD)
Person: HGL : Professor
Research output: Contribution to journal › Article › Academic › peer-review
Research output: Contribution to journal › Article › Academic › peer-review
Research output: Contribution to journal › Article › Academic › peer-review
Merkx, M. (Recipient), 2011
Prize: ERC › Starting › Scientific
Merkx, M. (Recipient), 2013
Prize: ERC › Proof of concept › Scientific
Dankers, P.Y.W. (Recipient), 2016
Prize: NWO › Vidi › Scientific
Jan Vinkenborg (Editorial board member)
Activity: Publication peer-review and editorial work types › Editorial activity › Scientific
13/01/23
1 item of Media coverage
Press/Media: Expert Comment
15/06/22
1 item of Media coverage
Press/Media: Expert Comment
29/09/21
1 item of Media coverage
Press/Media: Expert Comment
Marjo van Hoof (Content manager), Lieke van Gorp (Content manager) & Amy Broeders (Content manager)
Impact: Research Topic/Theme (at group level)
Marjo van Hoof (Content manager), Lieke van Gorp (Content manager) & Amy Broeders (Content manager)
Impact: Research Topic/Theme (at group level)
Marjo van Hoof (Content manager), Lieke van Gorp (Content manager) & Amy Broeders (Content manager)
Impact: Research Topic/Theme (at group level)
Supervisor: Subedi, N. (Supervisor 1), Conte, V. (Supervisor 2), Merkx, M. (Supervisor 2) & Smits, A. I. P. M. (Supervisor 2)
Student thesis: Master
Supervisor: Rosier, B. J. H. M. (Supervisor 1), van Aalen, E. A. (Supervisor 2) & Merkx, M. (Supervisor 2)
Student thesis: Master
Supervisor: Palmans, A. (Supervisor 1), Roosma, J. R. (Supervisor 2) & Meijer, B. (Supervisor 2)
Student thesis: Master