Content available in repository
Content available in repository
Organization profile
Introduction / mission
The Precision Medicine group focuses on designing and evaluating nanotherapeutics that regulate the immune response to treat a range of conditions, including cancer, cardiovascular and autoimmune diseases.
Highlighted phrase
Nanotechnology for immunotherapy
Organisational profile
Nanotechnology can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics. The innovation cascade involves developing biocompatible nanoimmunotherapeutics from natural molecular building blocks and comprises an innovative translational workflow, involving noninvasive imaging for testing on small and large animal disease models.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Precision Medicine is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Koen de Bruin, MSc
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Anne de Dreu
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Stijn R.J. Hofstraat
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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DNA storage in thermoresponsive microcapsules for repeated random multiplexed data access
Bögels, B. W. A., Nguyen, B. H., Ward, D., Gascoigne, L., Schrijver, D. P., Makri Pistikou, A. M., Joesaar, A., Yang, S., Voets, I. K., Mulder, W. J. M., Phillips, A., Mann, S., Seelig, G., Strauss, K., Chen, Y. J. & de Greef, T. F. A., 4 May 2023, (E-pub ahead of print) In: Nature Nanotechnology. XX, XResearch output: Contribution to journal › Article › Academic › peer-review
Open Access -
Engineering a Scalable and Orthogonal Platform for Synthetic Communication in Mammalian Cells
Makri Pistikou, A-M., Cremers, G. A. O., Nathalia, B. L., Bögels, B., de Dreu, A., Bezembinder, M., Eijkens, B. V., Stassen, O. M. J. A., Bouten, C. V. C., Merkx, M., Jerala, R. & de Greef, T. F. A., 2023, (Submitted) In: Nature Communications. XX, XResearch output: Contribution to journal › Article › Academic
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Engineering cytokine therapeutics
Deckers, J., Anbergen, T., Hokke, A. M., de Dreu, A., Schrijver, D. P., de Bruin, K., Toner, Y. C., Beldman, T., Spangler, J. B., de Greef, T. F. A., Grisoni, F., van der Meel, R., Joosten, L. A. B., Merkx, M., Netea, M. G. & Mulder, W. J. M., Apr 2023, In: Nature Reviews Bioengineering. 1, 4, p. 286-303 18 p.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
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In vivo imaging of cerebral glucose metabolism informs on subacute to chronic post-stroke tissue status – A pilot study combining PET and deuterium metabolic imaging
Meerwaldt, A. E. (Creator), Straathof, M. (Creator), Oosterveld, W. (Creator), van Heijningen, C. L. (Creator), van Leent, M. M. T. (Creator), Toner, Y. C. (Creator), Munitz, J. (Creator), Teunissen, A. J. P. (Creator), Daemen, C. C. (Creator), van der Toorn, A. (Creator), van Vliet, G. (Creator), van Tilborg, G. A. F. (Creator), De Feyter, H. M. M. L. (Creator), de Graaf, R. A. (Creator), Hol, E. M. (Creator), Mulder, W. J. M. (Creator) & Dijkhuizen, R. M. (Creator), SAGE Journals, 7 Jan 2023
Dataset
Prizes
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Co-development of a nanomedicine treatment and companion diagnostic test for castration-resistant prostate cancer
van der Meel, Roy (Recipient), 24 Jul 2015
Prize: NWO › Veni › Scientific
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Marie Skłodowska-Curie Action (Global Fellowship)
van der Meel, Roy (Recipient), 2 Apr 2015
Prize: Other › Fellowships & memberships › Scientific
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The Netherlands Society for Biochemistry and Molecular Biology (NVBMB) prize
van der Meel, Roy (Recipient), 2023
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
Press/Media
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NANOPAKKETJES BRENGEN RNA-MEDICATIE OP JUISTE PLEK
11/01/23
1 Media contribution
Press/Media: Public Engagement Activities
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Roy van der Meel develops RNA nanotechnology. ‘I’m a kind of postie who delivers medicines’
27/12/22
1 Media contribution
Press/Media: Public Engagement Activities
Student theses
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ELP-CCMV as a novel delivery system for the treatment of Lysosomal Storage Diseases
Author: Keij, S. R., 19 Apr 2021Supervisor: Vervoort, D. (Supervisor 1), van Hest, J. C. M. (Supervisor 2), Merkx, M. (Supervisor 2) & van der Meel, R. (Supervisor 2)
Student thesis: Master
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In vitro assessment of siRNA nanobiologics' stability and transfection efficiency
Author: Nugraha, E. G., 16 Jun 2022Supervisor: Kluza, E. (Supervisor 1), Hofstraat, S. R. J. (Supervisor 2) & Mulder, W. J. M. (Supervisor 2)
Student thesis: Master
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Optical Barcoding in PLGA-PEG Nanoparticles
Author: Meijers, R. B. B., 2021Supervisor: Albertazzi, L. (Supervisor 1), van Hest, J. C. M. (Supervisor 2), van der Meel, R. (Supervisor 2) & Ortiz Perez, A. (Supervisor 2)
Student thesis: Master