• Postbus 513, Helix Building

    5600 MB Eindhoven

    Netherlands

  • De Groene Loper 3, Helix Building (STO 3.39)

    5612 AE Eindhoven

    Netherlands

Organization profile

Introduction / mission

The Precision Medicine group focuses on designing and evaluating nanotherapeutics that regulate the immune response to treat a range of conditions, including cancer, cardiovascular and autoimmune diseases.

Highlighted phrase

Nanotechnology for immunotherapy

Organisational profile

Nanotechnology can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics. The innovation cascade involves developing biocompatible nanoimmunotherapeutics from natural molecular building blocks and comprises an innovative translational workflow, involving noninvasive imaging for testing on small and large animal disease models.

Fingerprint Dive into the research topics where Precision Medicine is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Atherosclerosis Medicine & Life Sciences
Nanoparticles Chemical Compounds
Medical nanotechnology Chemical Compounds
Inflammation Medicine & Life Sciences
Tropoelastin Medicine & Life Sciences
Myeloid Cells Medicine & Life Sciences
Lipids Chemical Compounds
Liposomes Engineering & Materials Science

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2019

2 Downloads (Pure)

An iterative sparse deconvolution method for simultaneous multicolor 19F-MRI of multiple contrast agents

Schoormans, J., Calcagno, C., Daal, M. R. R., Wüst, R. C. I., Faries, C., Maier, A., Teunissen, A. J. P., Naidu, S., Sanchez-Gaytan, B. L., Nederveen, A. J., Fayad, Z. A., Mulder, W. J. M., Coolen, B. F. & Strijkers, G. J., 10 Jul 2019, In : Magnetic Resonance in Medicine. 83, 1, p. 228-239 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Contrast Media
Artifacts
Fluorine
Noise
Cell Tracking
5 Citations (Scopus)

Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads

Kulkarni, J. A., Witzigmann, D., Leung, J., van der Meel, R., Zaifman, J., Darjuan, M. M., Grisch-Chan, H. M., Thöny, B., Tam, Y. Y. C. & Cullis, P. R., 14 May 2019, In : Nanoscale. 11, 18, p. 9023-9031 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipids
Fusion reactions
Nanoparticles
Polyethylene glycols
Gene therapy
1 Citation (Scopus)

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species

Binderup, T., Duivenvoorden, R., Fay, F., van Leent, M. M. T., Malkus, J., Baxter, S., Ishino, S., Zhao, Y., Sanchez-Gaytan, B., Teunissen, A. J. P., Frederico, Y. C. A., Tang, J., Carlucci, G., Lyashchenko, S., Calcagno, C., Karakatsanis, N., Soultanidis, G., Senders, M. L., Robson, P. M., Mani, V. & 12 others, Ramachandran, S., Lobatto, M. E., Hutten, B. A., Granada, J. F., Reiner, T., Swirski, F. K., Nahrendorf, M., Kjaer, A., Fisher, E. A., Fayad, Z. A., Pérez-Medina, C. & Mulder, W. J. M., 21 Aug 2019, In : Science Translational Medicine. 11, 506, eaaw7736.

Research output: Contribution to journalArticleAcademicpeer-review

Atherosclerosis
Swine
Animal Models
Nanomedicine
Rabbits

Prizes

Nanomedicine
Castration
Routine Diagnostic Tests
Prostatic Neoplasms
docetaxel

Marie Skłodowska-Curie Action (Global Fellowship)

Roy van der Meel (Recipient), 2 Apr 2015

Prize: OtherFellowships & membershipsScientific

Castration
Prostatic Neoplasms
Nanomedicine
Biomarkers
docetaxel

Activities 2018 2019

  • 4 Invited talk

A modular nanocarrier platform for delivery of siRNA and lipophilic prodrugs

Roy van der Meel (Speaker)
5 Feb 2019

Activity: Talk or presentation typesInvited talkScientific

Lipid nanoparticles enabling personalized vaccines for cancer immunotherapy

Roy van der Meel (Speaker)
16 Jan 2019

Activity: Talk or presentation typesInvited talkScientific

The Flying Dutchman: Managing an MSCA research project in Canada

Roy van der Meel (Speaker)
5 Nov 2018

Activity: Talk or presentation typesInvited talkProfessional