• Postbus 513, Helix Building

    5600 MB Eindhoven

    Netherlands

  • De Groene Loper 3, Helix Building (STO 3.39)

    5612 AE Eindhoven

    Netherlands

Organization profile

Introduction / mission

The Precision Medicine group focuses on designing and evaluating nanotherapeutics that regulate the immune response to treat a range of conditions, including cancer, cardiovascular and autoimmune diseases.

Highlighted phrase

Nanotechnology for immunotherapy

Organisational profile

Nanotechnology can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics. The innovation cascade involves developing biocompatible nanoimmunotherapeutics from natural molecular building blocks and comprises an innovative translational workflow, involving noninvasive imaging for testing on small and large animal disease models.

Fingerprint Dive into the research topics where Precision Medicine is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

  • Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Profiles

    Photo of Ewelina Kluza

    Ewelina Kluza, PhD

    Person: OBP : Supportive and management staff

    20102018
    Photo of Roy Meel van der
    20062020

    Research Output

    Defining trained immunity and its role in health and disease

    Netea, M. G., Domínguez-Andrés, J., Barreiro, L. B., Chavakis, T., Divangahi, M., Fuchs, E., Joosten, L. A. B., van der Meer, J. W. M., Mhlanga, M. M., Mulder, W. J. M., Riksen, N. P., Schlitzer, A., Schultze, J. L., Stabell Benn, C., Sun, J. C., Xavier, R. J. & Latz, E., 4 Mar 2020, In : Nature Reviews Immunology. 20, p. 375–388 14 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

    Open Access
  • 11 Citations (Scopus)

    Modular lipid nanoparticle platform technology for siRNA and lipophilic prodrug delivery

    van der Meel, R., Chen, S., Zaifman, J., Kulkarni, J. A., Zhang, X. R. S., Tam, Y. K., Bally, M. B., Schiffelers, R. M., Ciufolini, M. A., Cullis, P. R. & Tam, Y. Y. C., 16 Jan 2020, In : bioRxiv. 20 p.

    Research output: Contribution to journalArticleAcademic

    Open Access
    File
  • 15 Downloads (Pure)

    Multimodal positron emission tomography imaging to quantify uptake of 89Zr-labeled liposomes in the atherosclerotic vessel wall

    Lobatto, M. E., Binderup, T., Robson, P. M., Giesen, L. F. P., Calcagno, C., Witjes, J., Fay, F., Baxter, S., Wessel, C. H., Eldib, M., Bini, J., Carlin, S. D., Stroes, E. S. G., Storm, G., Kjaer, A., Lewis, J. S., Reiner, T., Fayad, Z. A., Mulder, W. J. M. & Pérez-Medina, C., 19 Feb 2020, In : Bioconjugate Chemistry. 31, 2, p. 360-368 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 2 Citations (Scopus)

    Prizes

  • Marie Skłodowska-Curie Action (Global Fellowship)

    Roy van der Meel (Recipient), 2 Apr 2015

    Prize: OtherFellowships & membershipsScientific

  • Activities

    • 4 Invited talk

    A modular nanocarrier platform for delivery of siRNA and lipophilic prodrugs

    Roy van der Meel (Speaker)
    5 Feb 2019

    Activity: Talk or presentation typesInvited talkScientific

    Lipid nanoparticles enabling personalized vaccines for cancer immunotherapy

    Roy van der Meel (Speaker)
    16 Jan 2019

    Activity: Talk or presentation typesInvited talkScientific

    The Flying Dutchman: Managing an MSCA research project in Canada

    Roy van der Meel (Speaker)
    5 Nov 2018

    Activity: Talk or presentation typesInvited talkProfessional