Research output per year
Research output per year
Organization profile
Introduction / mission
The Precision Medicine group focuses on designing and evaluating nanotherapeutics that regulate the immune response to treat a range of conditions, including cancer, cardiovascular and autoimmune diseases.
Highlighted phrase
Nanotechnology for immunotherapy
Organisational profile
Nanotechnology can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics. The innovation cascade involves developing biocompatible nanoimmunotherapeutics from natural molecular building blocks and comprises an innovative translational workflow, involving noninvasive imaging for testing on small and large animal disease models.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Dive into the research topics where Precision Medicine is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Koen de Bruin, MSc
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Anne de Dreu
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Stijn R.J. Hofstraat
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Regulating trained immunity with nanomedicine
van Leent, M. M. T., Priem, B., Schrijver, D. P., de Dreu, A., Hofstraat, S. R. J., Zwolsman, R., Beldman, T. J., Netea, M. G. & Mulder, W. J. M., 2022, (Accepted/In press) In: Nature Reviews Materials. XX, XResearch output: Contribution to journal › Review article › Academic › peer-review
Open Access -
A modular approach toward producing nanotherapeutics targeting the innate immune system
van Leent, M. M. T., Meerwaldt, A. E., Berchouchi, A., Toner, Y. C., Burnett, M., Klein, E. D., Vera Verschuur, A., Nauta, S. A., Munitz, J., Prévot, G., van Leeuwen, E. M., Ordikhani, F., Mourits, V. P., Calcagno, C., Robson, P. M., Soultanidis, G., Reiner, T., Joosten, R., Friedrich, H., Madsen, J. C. & 9 others, , 5 Mar 2021, In: Science Advances. 7, 10, 13 p., eabe7853.Research output: Contribution to journal › Article › Academic › peer-review
Open Access6 Citations (Scopus) -
Applications of elastin-like polypeptides in nanomedicine
Abdelghani, M., 9 Feb 2021, Eindhoven: Technische Universiteit Eindhoven. 153 p.Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
Open AccessFile
Prizes
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Co-development of a nanomedicine treatment and companion diagnostic test for castration-resistant prostate cancer
van der Meel, Roy (Recipient), 24 Jul 2015
Prize: NWO › Veni › Scientific
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Marie Skłodowska-Curie Action (Global Fellowship)
van der Meel, Roy (Recipient), 2 Apr 2015
Prize: Other › Fellowships & memberships › Scientific
Press / Media
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Australia: Icahn School of Medicine at Mount Sinai Receives Patent for 'Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis'
1/04/22
1 item of Media coverage
Press/Media: Expert Comment
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Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis
1/12/21
1 item of Media coverage
Press/Media: Expert Comment
Student theses
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ELP-CCMV as a novel delivery system for the treatment of Lysosomal Storage Diseases
Author: Keij, S. R., 19 Apr 2021Supervisor: Vervoort, D. (Supervisor 1), van Hest, J. C. M. (Supervisor 2), Merkx, M. (Supervisor 2) & van der Meel, R. (Supervisor 2)
Student thesis: Master
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The detection of circulating tumor cells based on the Warburg effect using droplet-based microfluidics
Author: Ypma, T. G., 27 Aug 2020Supervisor: Merkx, M. (Supervisor 1), Foolen, J. (Supervisor 2) & van der Meel, R. (Supervisor 2)
Student thesis: Master