Content available in repository
Content available in repository
Organisation profile
Introduction / mission
The Precision Medicine group focuses on designing and evaluating nanotherapeutics that regulate the immune response to treat a range of conditions, including cancer, cardiovascular and autoimmune diseases.
Highlighted phrase
Nanotechnology for immunotherapy
Organisation profile
Nanotechnology can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics. The innovation cascade involves developing biocompatible nanoimmunotherapeutics from natural molecular building blocks and comprises an innovative translational workflow, involving noninvasive imaging for testing on small and large animal disease models.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Precision Medicine is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Koen de Bruin, MSc
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Anne de Dreu
- Biomedical Engineering, Precision Medicine - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Merel Hendrikx
- Biomedical Engineering, Precision Medicine - Operations Technician
Person: OBP : Supportive and management staff
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A modular nanoparticle vaccine platform for tailored antigen and adjuvant delivery
de Dreu, A., Schrijver, D. P., Cremers, G. A. O., de Bruin, K., Vos, B. N., Anbergen, T., van Elsas, Y., Versteeg, I., Zwolsman, R., Deckers, J., Timmers, M., Roelofs, S., Darwish, Y., van der Staak, M., Priem, B., Maas, R. J. F., de Leeuw, P., Ros, G., Bartelet, B. & Hendrikx, M. & 14 others, , 2025, (Submitted) In: Nature Nanotechnology. XX, XResearch output: Contribution to journal › Article › Academic › peer-review
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Autonomous and tunable control of synthetic receptor activation using microRNAs
Nathalia, B. L., Meuleman, T. J., Makri Pistikou, A.-M., Doensen, W. H. M., Nijenhuis, W., Schrijver, D. P., Kapitein, L. C. & de Greef, T. F. A., 17 Mar 2025, (Submitted).Research output: Contribution to conference › Abstract › Academic
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Bioengineered Therapeutic Strategies to Rebalance the Immune System
Schrijver, D. P., 29 Jan 2025, Eindhoven: Eindhoven University of Technology. 205 p.Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
Datasets
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Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium
Deprez, J. (Creator), Verbeke, R. (Creator), Meulewaeter, S. (Creator), Aernout, I. (Creator), Dewitte, H. (Creator), Decruy, T. (Creator), Coudenys, J. (Creator), Van Duyse, J. (Creator), Van Isterdael, G. (Creator), Peer, D. (Creator), van der Meel, R. (Creator), De Smedt, S. C. (Contributor), Jacques, P. (Creator), Elewaut, D. (Creator) & Lentacker, I. (Creator), Figshare, 11 Jul 2023
DOI: 10.6084/m9.figshare.22800722, https://springernature.figshare.com/articles/dataset/Transport_by_circulating_myeloid_cells_drives_liposomal_accumulation_in_inflamed_synovium/22800722 and one more link, https://springernature.figshare.com/articles/dataset/Transport_by_circulating_myeloid_cells_drives_liposomal_accumulation_in_inflamed_synovium/22800722/1 (show fewer)
Dataset
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In vivo imaging of cerebral glucose metabolism informs on subacute to chronic post-stroke tissue status – A pilot study combining PET and deuterium metabolic imaging
Meerwaldt, A. E. (Creator), Straathof, M. (Creator), Oosterveld, W. (Creator), van Heijningen, C. L. (Creator), van Leent, M. M. T. (Creator), Toner, Y. C. (Creator), Munitz, J. (Creator), Teunissen, A. J. P. (Creator), Daemen, C. C. (Creator), van der Toorn, A. (Creator), van Vliet, G. (Creator), van Tilborg, G. A. F. (Creator), De Feyter, H. M. M. L. (Creator), de Graaf, R. A. (Creator), Hol, E. M. (Creator), Mulder, W. J. M. (Creator) & Dijkhuizen, R. M. (Creator), SAGE Journals, 7 Jan 2023
Dataset
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Machine learning-guided high throughput nanoparticle design
Ortiz-Perez, A. (Creator), van Tilborg, D. (Creator), van der Meel, R. (Creator), Grisoni, F. (Creator) & Albertazzi, L. (Creator), Zenodo, 28 Aug 2023
DOI: 10.5281/zenodo.8289605, https://zenodo.org/records/8289605
Dataset
Prizes
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Co-development of a nanomedicine treatment and companion diagnostic test for castration-resistant prostate cancer
van der Meel, R. (Recipient), 24 Jul 2015
Prize: NWO › Veni › Scientific
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Marie Skłodowska-Curie Action (Global Fellowship)
van der Meel, R. (Recipient), 2 Apr 2015
Prize: Other › Fellowships & memberships › Scientific
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The Netherlands Society for Biochemistry and Molecular Biology (NVBMB) prize
van der Meel, R. (Recipient), 2023
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
Press/Media
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Making your own tailor-made drugs
10/10/23
1 Media contribution
Press/Media: Public Engagement Activities
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Wat we nog meer kunnen verwachten van de Nobelprijswinnende mRNA-technologie
6/10/23
1 Media contribution
Press/Media: Public Engagement Activities
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Nobelprijs Geneeskunde naar belangrijk onderdeel mRNA-techniek
2/10/23
1 Media contribution
Press/Media: Expert Comment
Student theses
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ELP-CCMV as a novel delivery system for the treatment of Lysosomal Storage Diseases
Keij, S. R. (Author), Vervoort, D. (Supervisor 1), van Hest, J. C. M. (Supervisor 2), Merkx, M. (Supervisor 2) & van der Meel, R. (Supervisor 2), 19 Apr 2021Student thesis: Master
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In vitro assessment of siRNA nanobiologics' stability and transfection efficiency
Nugraha, E. G. (Author), Kluza, E. (Supervisor 1), Hofstraat, S. R. J. (Supervisor 2) & Mulder, W. J. M. (Supervisor 2), 16 Jun 2022Student thesis: Master
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Optical Barcoding in PLGA-PEG Nanoparticles
Meijers, R. B. B. (Author), Albertazzi, L. (Supervisor 1), van Hest, J. C. M. (Supervisor 2), van der Meel, R. (Supervisor 2) & Ortiz Perez, A. (Supervisor 2), 2021Student thesis: Master