Organisation profile
Introduction / mission
At PULS/e, our mission is to revolutionize medical imaging by pioneering advancements in ultrasound and photoacoustic technologies. We aim to transform clinical decision-making through early and precise diagnosis, non-invasive monitoring, and personalized treatment planning. By employing a wide range of scientific and engineering techniques—from hardware development and signal processing to clinical studies and first-in-man pilots—we strive to replace costly and hazardous imaging modalities with safe, cost-effective solutions.
Our ultimate goal is to enhance patient care, improve healthcare outcomes, and contribute to healthcare sustainability.
Highlighted phrase
Innovating sound and light to transform healthcare
Organisation profile
Ultrasound Imaging: The Future of Medical Diagnostics
Ultrasound imaging (US) is a key tool in modern diagnostics, used for rapid diagnosis, disease monitoring, and guiding interventions. Over the past two decades, it has advanced rapidly, becoming a safe, cost-effective alternative to other imaging methods. It is now widely used from tertiary to primary healthcare, reflecting the belief that "the future of medical imaging is sound."
Innovations and Advancements
To meet the demand for high-fidelity imaging, new concepts are being developed to overcome traditional US limitations. Innovations like photoacoustics, functional imaging, and model-based analysis provide detailed insights into tissue morphology and function. These advancements enable early diagnosis, continuous monitoring, and personalized treatment plans, improving patient outcomes and quality of life.
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Collaborations and top research areas from the last five years
Profiles
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Daniek A.C. van Aarle, MSc
- Biomedical Engineering - Doctoral Candidate
- Eindhoven MedTech Innovation Center - Doctoral Candidate
- Biomedical Engineering, Photoacoustics and Ultrasound Laboratory Eindhoven - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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María José Almario Escorcia
- Biomedical Engineering, Photoacoustics and Ultrasound Laboratory Eindhoven - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Projects
- 3 Active
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MEDEIA/TKI-HTSM/22.0501/TKI2212P12
Lopata, R. G. P. (Project Manager) & Severens, A. C. E. (Project member)
1/01/22 → 31/12/27
Project: Third tier
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PISANO/TKI/PPS/BMT
Lopata, R. G. P. (Project Manager) & van Aarle, D. A. C. (Project member)
1/09/21 → 31/08/26
Project: Third tier
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TKI-HTSM/20.0295/PPS2006 MEDUSA
Lopata, R. G. P. (Project Manager) & Gillissen, M. (Project member)
1/01/20 → 16/04/29
Project: Third tier
Research output
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Spatio-temporal registration of multi-perspective 3D echocardiography for improved strain estimation
Sjoerdsma, M. (Corresponding author), Bouwmeester, S., van Heesch, F., Houthuizen, P. & Lopata, R. G. P., Jan 2026, In: Medical Image Analysis. 107, Part A, 12 p., 103791.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Downloads (Pure) -
Toward ICE-XRF fusion: real-time pose estimation of the intracardiac echo probe in 2D X-ray using deep learning
Severens, A. (Corresponding author), Meijs, M., Pai Raikar, V. & Lopata, R., Jan 2026, In: International Journal of Computer Assisted Radiology and Surgery. 21, 1, p. 59-69 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Downloads (Pure) -
Ultrasound-based personalized hemodynamic modeling of large regions of the peripheral artery using a novel optical tracking approach
Gillissen, M. (Corresponding author), Piek, L., van der Horst, A., van Sambeek, M., van de Vosse, F. & Lopata, R., Jan 2026, In: Journal of Biomechanics. 194, 9 p., 113020.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)5 Downloads (Pure)
Press/Media
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Maastricht University Reports Findings in Photoacoustics (Deep learning assisted classification of spectral photoacoustic imaging of carotid plaques)
Lopata, R. G. P. & van Sambeek, M. R. H. M.
15/09/23
1 item of Media coverage
Press/Media: Expert Comment
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Parents bring photo of deceased son on board cruise ship to fulfil his dream
11/09/23
1 item of Media coverage
Press/Media: Expert Comment
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Eindhoven University of Technology Reports Findings in Technology (Enabling strain imaging in realistic Eulerian ultrasound simulation methods)
Rutten, M. C. M., Wu, M., Muller, J.-W. & Schwab, H.-M.
25/08/23
1 item of Media coverage
Press/Media: Expert Comment
Student theses
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3D Camera Monitoring of Rodent Irradiation Geometry for High Precision Shielding
Slegt, V. J. (Author), Raaijmakers, A. J. E. (Supervisor 1), Pluim, J. P. W. (Supervisor 2), Schwab, H.-M. (Supervisor 2), Staut, N. (External coach) & Verhaegen, F. (External coach), 29 Sept 2022Student thesis: Master
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3D flow velocity imaging based on high frame rate ultrasound acquisitions
Verheijen, F. B. T. (Author), Lopata, R. G. P. (Supervisor 1), Schwab, H.-M. (Supervisor 2) & de Hoop, H. (Supervisor 2), 25 May 2023Student thesis: Master
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3-D geometry assessment of lower extremities using multi-perspective, freehand, 2-D ultrasound for improved decision making in peripheral arterial occlusive disease
Romme, C. J. A. (Author), Lopata, R. G. P. (Supervisor 1), van Sambeek, M. R. H. M. (Supervisor 2), Jansen, L. C. (Supervisor 2), Gillissen, M. (Supervisor 2) & de Ruijter, J. (Supervisor 2), 25 Aug 2022Student thesis: Master