Orthopaedic Biomechanics

2025

Biomimetic design of articular cartilage tissue engineering constructs: A focus on the cell microenvironment

van Mourik, M., 30 Jan 2025, Eindhoven: Eindhoven University of Technology. 160 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

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174 Downloads (Pure)

Improving ACL reconstruction: understanding and mitigating postoperative complications

Spierings, J. M. H., 23 Jun 2025, (Accepted/In press) Eindhoven: Eindhoven University of Technology. 141 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

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25 Downloads (Pure)

2023

A biomimetic artificial cervical disc replacement: biomaterial and biomechanical design characterization

Jacobs, C. A. M., 19 Apr 2023, Eindhoven: Eindhoven University of Technology. 158 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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293 Downloads (Pure)

A nucleus pulposus explant model to study intervertebral disc degeneration and regeneration

Salzer, E. M., 1 Sept 2023, Eindhoven: Eindhoven University of Technology. 107 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Exploring the effect of osmotic pressure on creating load bearing regenerative cartilage implants

Schuiringa, G. H., 21 Sept 2023, Eindhoven: Eindhoven University of Technology. 166 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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351 Downloads (Pure)

Ex vivo bone explant cultures for evaluation of remodeling and bone substitutes

Cramer, E. E. A., 1 Nov 2023, Eindhoven: Eindhoven University of Technology. 203 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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137 Downloads (Pure)

Microenvironmental advancement and miniaturization of human in vitro bone models

Vis, M. A. M., 19 Jun 2023, Eindhoven: Eindhoven University of Technology. 150 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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340 Downloads (Pure)

Notochordal cell-derived therapeutic approaches for intervertebral disc regeneration

Schmitz, T. C., 6 Dec 2023, Eindhoven: Eindhoven University of Technology. 179 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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324 Downloads (Pure)

Serum Substitute Medium for Bone Tissue Engineering Applications

Ansari, S., 10 May 2023, Eindhoven: Eindhoven University of Technology. 208 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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165 Downloads (Pure)

The amazing osteoclast: Towards an in vitro 3D co-culture model of bone

Remmers, S. J. A., 14 Mar 2023, Eindhoven: Eindhoven University of Technology. 132 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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203 Downloads (Pure)

2022

Advancing tissue engineering of in vitro human bone models

de Wildt, B. W. M., 4 Nov 2022, Eindhoven: Eindhoven University of Technology. 278 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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167 Downloads (Pure)

A human ex vivo model for evaluation of osteochondral regeneration and integration

Kleuskens, M. W. A., 23 Sept 2022, Eindhoven: Eindhoven University of Technology. 145 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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176 Downloads (Pure)

Biotribology of cartilage resurfacing implants

Damen, A. H. A., 16 Sept 2022, Eindhoven: Eindhoven University of Technology. 167 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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265 Downloads (Pure)

2021

A Multi-Scale Investigation of Tendon- and Ligament Disorders

van Vijven, M., 8 Dec 2021, Eindhoven: Eindhoven University of Technology. 184 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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52 Downloads (Pure)

Nature-inspired Biomaterials Discovery for Tendon Tissue Engineering

Dede Eren, A., 9 Jun 2021, Eindhoven: Technische Universiteit Eindhoven. 215 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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474 Downloads (Pure)

2019

Bioactive glass as bone graft substitute: in vitro assessment of the mechanical and biological properties

van Gestel, N. A. P., 31 Oct 2019, Eindhoven: Technische Universiteit Eindhoven. 181 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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202 Downloads (Pure)

Environmental stimuli for controlled bone tissue engineering applications

Melke, J., 14 Mar 2019, Eindhoven: Technische Universiteit Eindhoven. 172 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

22 Downloads (Pure)

Estimations of mechanical properties of intact and damaged bone from high resolution CT-images

Arias Moreno, A. J., 27 Jun 2019, Eindhoven: Technische Universiteit Eindhoven. 156 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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272 Downloads (Pure)

Strain-induced initiation and progression of articular cartilage damage

Henao Murillo, L., 25 Jun 2019, Eindhoven: Technische Universiteit Eindhoven. 127 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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132 Downloads (Pure)

2018

Towards understanding of cartilage damage development around focal defects and implants

Heuijerjans, A., 30 Oct 2018, Eindhoven: Technische Universiteit Eindhoven. 106 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

20 Downloads (Pure)

2016

Notochordal cell-based therapies for intervertebral disc regeneration

de Vries, S. A. H., 21 Nov 2016, Eindhoven: Technische Universiteit Eindhoven. 142 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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512 Downloads (Pure)

Notochordal cells and tissue explants for intervertebral disc regeneration

Arkesteijn, I. T. M., 28 Jun 2016, Eindhoven: Technische Universiteit Eindhoven. 143 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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710 Downloads (Pure)

The development of a degenerative spinal motion segment : moving towards the unknown

van Rijsbergen, M. M., 6 Oct 2016, Eindhoven: Technische Universiteit Eindhoven. 144 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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832 Downloads (Pure)

Towards predicting chondroprotective capabilities of meniscus prostheses

Parraga Quiroga, J. M., 31 May 2016, Eindhoven: Technische Universiteit Eindhoven. 135 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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269 Downloads (Pure)

2014

Novel strategies for monitoring intervertebral disc degeneration and regeneration

Dittmar, R., 2014, Eindhoven: Technische Universiteit Eindhoven. 90 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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412 Downloads (Pure)

Towards a damage model for articular cartilage

Hosseini, S. M., 2014, Eindhoven: Technische Universiteit Eindhoven. 114 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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1072 Downloads (Pure)

2013

A physiological in vitro model of intervertebral disc tissue

Dijk, van, B. G. M., 2013, Eindhoven: Technische Universiteit Eindhoven. 131 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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830 Downloads (Pure)

Deciphering the secret message within bone microstructure

Christen, P., 2013, Eindhoven: Technische Universiteit Eindhoven. 112 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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317 Downloads (Pure)

Patient specific prediction of bone failure using microstructure-enhanced continuum finite element models

Hazrati Marangalou, J., 2013, Eindhoven: Technische Universiteit Eindhoven. 116 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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771 Downloads (Pure)

2012

Computer-aided cartilage tissue-engineering : a numerical evaluation of the influence of inhomogeneities, collagen architecture and temporal culture effects

Khoshgoftar, M., 2012, Eindhoven: Technische Universiteit Eindhoven. 134 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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162 Downloads (Pure)

Development of a biomimetic artificial intervertebral disc

Broek, van den, P. R., 2012, Eindhoven: Technische Universiteit Eindhoven. 146 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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901 Downloads (Pure)

Strategies for engineering cartilage with improved content and organization

Kock, L. M., 2012, Eindhoven: Technische Universiteit Eindhoven. 122 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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346 Downloads (Pure)

2011

Mechanoregulated bone adaptation in osteoarthritis

Cox, L. G. E., 2011, Eindhoven: Technische Universiteit Eindhoven. 143 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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432 Downloads (Pure)

2010

Simulations of bone remodeling at the cellular scale

Oers, van, R. F. M., 2010, Eindhoven: Technische Universiteit Eindhoven. 108 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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500 Downloads (Pure)

2009

How periosteum is involved in long bone growth

Foolen, J., 2009, Eindhoven: Technische Universiteit Eindhoven. 111 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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1085 Downloads (Pure)

Propagating discontinuities in ionized porous media

Kraaijeveld, F., 2009, Eindhoven: Technische Universiteit Eindhoven. 143 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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166 Downloads (Pure)

The influence of nutrient deprivation on nucleus pulposus cells in vivo and in vitro

Werf, van der, M. J., 2009, Eindhoven: Technische Universiteit Eindhoven. 102 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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833 Downloads (Pure)

2008

In vivo assessment of changes in bone due to osteoporosis and its possible treatments

Brouwers, J. E. M., 2008, Eindhoven: Technische Universiteit Eindhoven. 156 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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559 Downloads (Pure)

Putting pressure on the spine : an osmoviscoelastic FE model of the intervertebral disc

Schroder, Y., 2008, Eindhoven: Technische Universiteit Eindhoven. 91 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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391 Downloads (Pure)

2007

Mixed finite element for swelling of cartilaginous tissues

Malakpoor, K., 2007, Eindhoven: Technische Universiteit Eindhoven. 133 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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408 Downloads (Pure)

2006

Analyses of trabecular bone failure

Verhulp, E., 2006, Eindhoven: Technische Universiteit Eindhoven. 97 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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788 Downloads (Pure)

Plasma needle : non-thermal atmospheric plasmas in dentistry

Sladek, R. E. J., 2006, Eindhoven: Technische Universiteit Eindhoven. 159 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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2387 Downloads (Pure)

2005

An explanation for the onset of mechanically induced cartilage damage

Wilson, W., 2005, Eindhoven: Technische Universiteit Eindhoven. 146 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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521 Downloads (Pure)

Plasma needle : exploring biomedical applications of non-thermal plasmas

Kieft, I. E., 2005, Eindhoven: Technische Universiteit Eindhoven. 147 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

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937 Downloads (Pure)

2003

Towards a rational definition of osteoporosis

Homminga, J. J., 2003, Eindhoven: Technische Universiteit Eindhoven. 104 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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623 Downloads (Pure)

1986

Non-linear finite element models of the beating left ventricle and the intramyocardial coronary circulation

Huyghe, J. M. R. J., 1986, Eindhoven: Technische Universiteit Eindhoven. 270 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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434 Downloads (Pure)

1979

Some fundamental aspects of human joint replacement : analyses of stresses and heat conduction in bone-prosthesis structures

Huiskes, R., 1979, Eindhoven: Technische Hogeschool Eindhoven. 209 p.

Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access

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924 Downloads (Pure)

Orthopaedic Biomechanics

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