Research Output per year
Organization profile
Introduction / mission
We explore and develop (regenerative) treatment strategies for orthopaedic injuries and disorders based on a thorough understanding of musculoskeletal tissue mechanobiology and biomechanical function.
Highlighted phrase
Novel treatment strategies for an ever-active ageing population
Organisational profile
Human cells produce, maintain and adapt musculoskeletal tissues such as bone and cartilage as a response to their biophysical environment, both in health and disease. In our ever-aging population, orthopaedic injuries and degenerative diseases have become more prevalent, with an increasing socioeconomic impact. Current treatment methods with purely synthetic devices may be limited in view of the increasing longevity and high level of activity of modern day humans. The Orthopaedic Biomechanics research group combines engineering and biology to expand our understanding of musculoskeletal tissues and to develop (regenerative) treatment strategies. These are currently applied to bone, articular cartilage, intervertebral disc and tendons/ligaments.
Fingerprint Dive into the research topics where Orthopaedic Biomechanics is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Profiles
Research Output
29th annual conference of the European Society for Biomaterials
Habibovic, P., Hofmann, S. & van den Beucken, J., 1 Jan 2020, In : Biomaterials Science. 8, 1, p. 16-17 2 p.Research output: Contribution to journal › Editorial › Academic
Open Access
Accuracy of beam theory for estimating bone tissue modulus and yield stress from 3-point bending tests on rat femora
Arias-Moreno, A. J., Ito, K. & van Rietbergen, B., 5 Mar 2020, In : Journal of Biomechanics. 101, 8 p., 109654.Research output: Contribution to journal › Article › Academic › peer-review
Changes in scaffold porosity during bone tissue engineering in perfusion bioreactors considerably affect cellular mechanical stimulation for mineralization
Zhao, F., Lacroix, D., Ito, K., van Rietbergen, B. & Hofmann, S., Jun 2020, In : Bone Reports. 12, 7 p., 100265.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Datasets
Database of femur samples
Hazrati Marangalou, J. (Creator), Technische Universiteit Eindhoven, 2013
DOI: https://doi.org/10.4121/uuid:4ae59365-92f0-480b-a899-ade34bc84a00
Dataset
Prizes
An ex vivo platform to screen drug effects on bone
Sandra Hofmann (Recipient), 20 Apr 2020
Prize: ERC › Proof of concept › Scientific
ASIA / IPD 2017 (KIVI) Educational Knee Simulator
Martijn van Lith (Recipient), Rick Tielen (Recipient), Tim Faber (Recipient), Thijs Custers (Recipient), Demi Römkes (Recipient), Sjoerd Peters (Recipient), Theo Beljaars (Recipient), Sonja Voorn (Recipient) & Rob P.A. Janssen (Recipient), 5 Jul 2017
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
Best Oral Presentation
Stefan Remmers (Recipient), 4 Dec 2015
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
Activities
Surgical techniques in ACL reconstruction of the knee
Rob P.A. Janssen (Keynote speaker)24 Mar 2020
Activity: Talk or presentation types › Keynote talk › Scientific
Pediatric anterior cruciate ligament injuries
Rob P.A. Janssen (Keynote speaker)24 Mar 2020
Activity: Talk or presentation types › Keynote talk › Scientific
Remodelling of anterior cruciate ligament autografts
Rob P.A. Janssen (Keynote speaker)24 Mar 2020
Activity: Talk or presentation types › Keynote talk › Scientific
Press / Media
Eindhoven University of Technology: ERC Proof of Concept Grant for Screening Drug Effects on Bone in 3D
2/05/20 → 4/05/20
2 items of Media coverage
Press/Media: Expert Comment
EUR 350,000 for Eindhoven University of Technology Pilot With Gel That Restores Spinal Disc Degeneration
2/04/20
1 item of Media coverage
Press/Media: Expert Comment
Kunnen wetenschappers het lichaam helpen zichzelf te genezen?
Sandra Hofmann & Anthal I.P.M. Smits
5/03/20
1 Media contribution
Press/Media: Public Engagement Activities
Research areas
Bone Function and Structure
Evelien Arts - Arts (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
Bone Tissue Engineering
Evelien Arts - Arts (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
Intervertebral Disc
Evelien Arts - Arts (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
Student theses
3D human osteoblast - osteoclast in vitro co-culture
Author: Remmers, S. & Mayer, D., 2019Supervisor: Remmers, S. (Supervisor 1), Melke, J. (Supervisor 1), Hofmann, S. (Supervisor 1), Ito, K. (Supervisor 1) & Teuschl, A. (External person) (Supervisor 2)
Student thesis: Master
A 3D co-culture model of mesenchymal stem cells and endothelial cells to promote vascularization and osteogenesis in bone tissue engineering
Author: Cramer, E., 29 Nov 2018Supervisor: Melke, J. (Supervisor 1) & Hofmann, S. (Supervisor 2)
Student thesis: Master
A microtissue platform as screening method for ACL reconstructive surgery outcome: towards personalized rehabilitation
Author: Kimenai, J., 30 Jan 2020Supervisor: Ito, K. (Supervisor 1), van der Steen, M. (External person) (External coach) & Foolen, J. (Supervisor 2)
Student thesis: Master