Content available in repository
Content available in repository
Organization profile
Introduction / mission
We explore and develop (regenerative) treatment strategies for orthopaedic injuries and disorders based on a thorough understanding of musculoskeletal tissue mechanobiology and biomechanical function.
Highlighted phrase
Novel treatment strategies for an ever-active ageing population
Organisational profile
Human cells produce, maintain and adapt musculoskeletal tissues such as bone and cartilage as a response to their biophysical environment, both in health and disease. In our ever-aging population, orthopaedic injuries and degenerative diseases have become more prevalent, with an increasing socioeconomic impact. Current treatment methods with purely synthetic devices may be limited in view of the increasing longevity and high level of activity of modern day humans. The Orthopaedic Biomechanics research group combines engineering and biology to expand our understanding of musculoskeletal tissues and to develop (regenerative) treatment strategies. These are currently applied to bone, articular cartilage, intervertebral disc and tendons/ligaments.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Parisa Akhlaghi
- Biomedical Engineering, Orthopaedic Biomechanics - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Sana Ansari
- Biomedical Engineering, Orthopaedic Biomechanics - Doctoral Candidate
- Biomedical Engineering, Bioengineering Bone - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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A biomimetic artificial cervical disc replacement: biomaterial and biomechanical design characterization
Jacobs, C. A. M., 19 Apr 2023, Eindhoven: Eindhoven University of Technology. 158 p.Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
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A dialysis medium refreshment cell culture set-up for an osteoblast-osteoclast coculture
Vis, M. A. M., de Wildt, B. W. M., Ito, K. & Hofmann, S., Apr 2023, In: Biotechnology and Bioengineering. 120, 4, p. 1120-1132 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Downloads (Pure) -
Anterior cruciate ligament rehabilitation for the 10 to 18 year old adolescent athlete: practice guidelines based on International Delphi Consensus
van Melick, N., Dietvorst, M., van Oort, MIAM., Claessens, RLA., Janssen, R. P. A. & Bogie, R., 2023.Research output: Contribution to conference › Poster
Datasets
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Translation and transcultural validation of the Dutch hospital for special surgery paediatric functional activity brief scale (HSS Pedi-FABS)
Dietvorst, M. (Creator), Janssen, R. P. A. (Creator), van den Berg, L. E. (Creator), van de Kerkhof, T. M. (Creator) & van der Steen, M. C. (Creator), Figshare, 7 Oct 2021
DOI: 10.6084/m9.figshare.c.5651026
Dataset
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Limited evidence for return to sport testing after ACL reconstruction in children and adolescents under 16 years: a scoping review
Dietvorst, M. (Creator), Brzoskowski, M. H. (Creator), van der Steen, M. (Contributor), Delvaux, E. (Creator), Janssen, R. P. A. (Creator) & Engelen-van Melick, N. (Contributor), Figshare, 16 Oct 2020
DOI: 10.6084/m9.figshare.c.5176960
Dataset
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Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome – a diagnostic in vitro tissue remodeling platform
van Vijven, M. (Contributor), van Groningen, B. (Contributor), Kimenai, J. N. (Creator), van der Steen, M. C. (Contributor), van Doeselaar, M. (Contributor), Janssen, R. P. A. (Creator), Ito, K. (Creator) & Foolen, J. (Creator), Figshare, 5 Jul 2020
DOI: 10.6084/m9.figshare.c.5049755
Dataset
Prizes
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An ex vivo platform to screen drug effects on bone
Hofmann, Sandra (Recipient), 20 Apr 2020
Prize: ERC › Proof of concept › Scientific
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ASIA / IPD 2017 (KIVI) Educational Knee Simulator
van Lith, Martijn (Recipient), Tielen, Rick (Recipient), Faber, Tim (Recipient), Custers, Thijs (Recipient), Römkens, Demi D.I.A. (Recipient), Peters, Sjoerd (Recipient), Beljaars, Theo (Recipient), Voorn, Sonja (Recipient) & Janssen, Rob P.A. (Recipient), 5 Jul 2017
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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Best Oral Presentation
Remmers, Stefan J.A. (Recipient), 4 Dec 2015
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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32nd annual Arthroscopy & Arthroplasty Utrecht Courses 2023
Rob P.A. Janssen (Organiser)
3 Jul 2023 → 7 Jul 2023Activity: Participating in or organising an event types › Workshop, seminar, course or exhibition › Scientific
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Live Event Voorste-kruisbandletsel bij kinderen
Rob P.A. Janssen (Organiser) & Nicky van Melick (Organiser)
1 Mar 2023Activity: Participating in or organising an event types › Workshop, seminar, course or exhibition › Professional
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ACL injuries in children: outcome, complications & future perspectives
Rob P.A. Janssen (Speaker)
1 Mar 2023Activity: Talk or presentation types › Keynote talk › Professional
Courses
Press/Media
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Eindhoven University of Technology Researchers Broaden Understanding of Extracellular Matrix Proteins (A decellularized and sterilized human meniscus allograft for off-the-shelf meniscus replacement)
Jasper Foolen, Keita Ito, J.M.H. Spierings, Jorge Uquillas Paredes & Amal Mansoor
28/12/22
1 item of Media coverage
Press/Media: Expert Comment
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-Eindhoven University of Technology : New ways to grow human 'mini-bones'
10/11/22
2 items of Media coverage
Press/Media: Expert Comment
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Impacts
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Bone Function and Structure
Evelien Arts-Arts (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
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Bone Tissue Engineering
Evelien Arts-Arts (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
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Intervertebral Disc
Evelien Arts-Arts (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
Student theses
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3D human osteoblast - osteoclast in vitro co-culture
Author: Remmers, S. & Mayer, D., 2019Supervisor: Remmers, S. (Supervisor 1), Melke, J. (Supervisor 1), Hofmann, S. (Supervisor 1), Ito, K. (Supervisor 1) & Teuschl, A. (External person) (Supervisor 2)
Student thesis: Master
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3D reconstruction of coronary artery centerlines from two 2D angiography-based planar projections
Author: Berendsen, A. J., 11 Oct 2021Supervisor: van de Vosse, F. N. (Supervisor 1), van 't Veer, M. (Supervisor 2), van Rietbergen, B. (Supervisor 2) & Bakker, L. M. M. L. (Supervisor 2)
Student thesis: Master
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A 3D co-culture model of mesenchymal stem cells and endothelial cells to promote vascularization and osteogenesis in bone tissue engineering
Author: Cramer, E., 29 Nov 2018Supervisor: Melke, J. (Supervisor 1) & Hofmann, S. (Supervisor 2)
Student thesis: Master