Research Output per year
Organization profile
Introduction / mission
We explore and develop (regenerative) treatment strategies for orthopaedic injuries and disorders based on a thorough understanding of musculoskeletal tissue mechanobiology and biomechanical function.
Highlighted phrase
Novel treatment strategies for an ever-active ageing population
Organisational profile
Human cells produce, maintain and adapt musculoskeletal tissues such as bone and cartilage as a response to their biophysical environment, both in health and disease. In our ever-aging population, orthopaedic injuries and degenerative diseases have become more prevalent, with an increasing socioeconomic impact. Current treatment methods with purely synthetic devices may be limited in view of the increasing longevity and high level of activity of modern day humans. The Orthopaedic Biomechanics research group combines engineering and biology to expand our understanding of musculoskeletal tissues and to develop (regenerative) treatment strategies. These are currently applied to bone, articular cartilage, intervertebral disc and tendons/ligaments.
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Profiles
Maria Andreis
- Department of Biomedical Engineering, Orthopaedic Biomechanics - University Researcher
Person: OWP : University Teacher / Researcher
Sana Ansari
- Department of Biomedical Engineering, Orthopaedic Biomechanics - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
J.J.C. (Chris) Arts
- Department of Biomedical Engineering, Orthopaedic Biomechanics - Associate Professor
Person: UHD : Associate Professor
Research Output 1974 2019
A multiscale computational fluid dynamics approach to simulate the micro-fluidic environment within a tissue engineering scaffold with highly irregular pore geometry
Zhao, F., Melke, J., Ito, K., van Rietbergen, B. & Hofmann, S., 14 Jun 2019, In : Biomechanics and Modeling in Mechanobiology.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Tissue Scaffolds
Tissue Engineering
Scaffold
Microfluidics
Fluidics
An improved growth guidance system for children with scoliosis: design of a screw guide and spacer
Gabriels, F., 11 Mar 2019, Eindhoven: Technische Universiteit Eindhoven. 59 p.Research output: Thesis › Pd Eng Thesis › Academic
Child Guidance
Scoliosis
Mebendazole
Toes
Polyethylene
A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: Towards in situ tissue-engineered vascular accesses for haemodialysis
van Uden, S., Vanerio, N., Catto, V., Bonandrini, B., Tironi, M., Figliuzzi, M., Remuzzi, A., Kock, L., Redaelli, A. C. L., Greco, F. G. & Riboldi, S. A., 1 Mar 2019, In : Biomedical Materials. 14, 2, p. 025007 18 p., 025007Research output: Contribution to journal › Article › Academic › peer-review
Fibroins
Polyurethanes
Silk
Grafts
Tissue
Datasets
Database of femur samples
Hazrati Marangalou, J. (Creator), Technische Universiteit Eindhoven, 2013
DOI: https://doi.org/10.4121/uuid:4ae59365-92f0-480b-a899-ade34bc84a00
Dataset
Prizes
Best Oral Presentation
Stefan Remmers (Recipient), 4 Dec 2015
Recognition: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
BME Research Day Poster Award (second place)
Nicole van Gestel (Recipient), 4 Apr 2018
Recognition: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
Intentional control of mineralized ECM deposition in bone tissue engineering
Sandra Hofmann Boss (Recipient), 1 Sep 2013
Recognition: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
Tissue Engineering
Bone and Bones
Press / Media
WIPO PUBLISHES PATENT OF TECHNISCHE UNIVERSITEIT EINDHOVEN AND RWTH AACHEN FOR "A BIOMIMETIC FUNCTIONAL AND REGENERATIVE CARTILAGE IMPLANT" (DUTCH, GERMAN INVENTORS)
30/04/18
1 item of media coverage
Press/Media: Expert Comment
WIPO PUBLISHES PATENT OF TECHNISCHE UNIVERSITEIT EINDHOVEN FOR "NOTOCHORDAL CELL MATRIX AS A STIMULANT FOR INTERVERTEBRAL DISC REGENERATION" (DUTCH INVENTORS)
23/07/17
1 item of media coverage
Press/Media: Expert Comment
REMOTE: Real-time monitoring of load induced remodeling in tissue-engineered bone
14/04/17
1 item of media coverage
Press/Media: Expert Comment
Research areas
Bone Function and Structure
Bone Tissue Engineering
Intervertebral Disc
Student theses
A 3D co-culture model of mesenchymal stem cells and endothelial cells to promote vascularization and osteogenesis in bone tissue engineering
Author: Cramer, E., 29 Nov 2018Supervisor: Melke, J. (Supervisor 1) & Hofmann, S. (Supervisor 2)
Student thesis: Master
Assessing strain and damage in cartilage explants with ultrasound
Author: Stavenuiter, I., 31 Jan 2019Supervisor: Ito, K. (Supervisor 1), van Donkelaar, R. (Supervisor 2), Lopata, R. (Supervisor 2) & van de Vosse, F. (Supervisor 2)
Student thesis: Master
Bioactive glass granules as bone graft substitute in osteomyelitic defects: application in load-bearing defects and a 2-year case study
Author: Gabriels, F., 26 Jun 2017Supervisor: Ito, K. (Supervisor 1), van Rietbergen, B. (Supervisor 2), Arts, J. (External coach), Geurts, J. (External person) (External coach), Bovendeerd, P. (Supervisor 2) & van Gestel, N. (Supervisor 2)
Student thesis: Master