Research output per year
Research output per year
Organization profile
Introduction / mission
We explore and develop (regenerative) treatment strategies for orthopaedic injuries and disorders based on a thorough understanding of musculoskeletal tissue mechanobiology and biomechanical function.
Highlighted phrase
Novel treatment strategies for an ever-active ageing population
Organisational profile
Human cells produce, maintain and adapt musculoskeletal tissues such as bone and cartilage as a response to their biophysical environment, both in health and disease. In our ever-aging population, orthopaedic injuries and degenerative diseases have become more prevalent, with an increasing socioeconomic impact. Current treatment methods with purely synthetic devices may be limited in view of the increasing longevity and high level of activity of modern day humans. The Orthopaedic Biomechanics research group combines engineering and biology to expand our understanding of musculoskeletal tissues and to develop (regenerative) treatment strategies. These are currently applied to bone, articular cartilage, intervertebral disc and tendons/ligaments.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Sana Ansari
- Biomedical Engineering, Bioengineering Bone - Doctoral Candidate
- Biomedical Engineering, Orthopaedic Biomechanics - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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J.J.C. (Chris) Arts
- Biomedical Engineering, Orthopaedic Biomechanics - University Lecturer
Person: OWP : University Teacher / Researcher
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Alkaline Phosphatase Activity of Serum Affects Osteogenic Differentiation Cultures
Ansari, S., Ito, K. & Hofmann, S., 19 Apr 2022, In: ACS Omega. 7, 15, p. 12724-12733 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
A tailored intervention does not reduce low value MRI’s and arthroscopies in degenerative knee disease when the secular time trend is taken into account: a difference-in-difference analysis
Rietbergen, T., Marang-van de Mheen, P. J., de Graaf, J., Diercks, R. L., Janssen, R. P. A., van der Linden-van der Zwaag, H. M. J., van den Akker-van Marle, M. E., Steyerberg, E. W., Nelissen, R. G. H. H., van Bodegom-Vos, L., Pander, P., Hofstee, D. J., van Geenen, R. C. I., Koenraadt, K. L. M., Onderwater, J. P. A. H., Kleinlugtenbelt, Y. V., Gosens, T., Klos, T. V. S., Rijk, P. C., Dijkstra, B. & 8 others, , 7 Apr 2022, (E-pub ahead of print) In: Knee Surgery, Sports Traumatology, Arthroscopy. XX, XResearch output: Contribution to journal › Article › Academic › peer-review
Open Access -
Biodegradable hydrogel scaffolds based on 2-hydroxyethyl methacrylate, gelatin, poly(β-amino esters), and hydroxyapatite
Filipović, V. V., Babić Radić, M. M., Vuković, J. S., Vukomanović, M., Rubert, M., Hofmann, S., Müller, R. & Tomić, S. L., Jan 2022, In: Polymers. 14, 1, 17 p., 18.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)4 Downloads (Pure)
Datasets
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Translation and transcultural validation of the Dutch hospital for special surgery paediatric functional activity brief scale (HSS Pedi-FABS)
Dietvorst, M. (Creator), Janssen, R. P. A. (Creator), van den Berg, L. E. (Creator), van de Kerkhof, T. M. (Creator) & van der Steen, M. C. (Creator), Figshare, 7 Oct 2021
DOI: 10.6084/m9.figshare.c.5651026
Dataset
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Database of femur samples
Hazrati Marangalou, J. (Creator), van Rietbergen, B. (Contributor) & Ito, K. (Contributor), Technische Universiteit Eindhoven, 7 Dec 2013
DOI: 10.4121/uuid:4ae59365-92f0-480b-a899-ade34bc84a00
Dataset
Prizes
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An ex vivo platform to screen drug effects on bone
Hofmann, Sandra (Recipient), 20 Apr 2020
Prize: ERC › Proof of concept › Scientific
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ASIA / IPD 2017 (KIVI) Educational Knee Simulator
van Lith, M. (Recipient), Tielen, R. (Recipient), Faber, T. (Recipient), Custers, T. (Recipient), Römkens, D. D. I. A. (Recipient), Peters, S. (Recipient), Beljaars, T. (Recipient), Voorn, S. (Recipient) & Janssen, Rob P.A. (Recipient), 5 Jul 2017
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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Best Oral Presentation
Remmers, Stefan J.A. (Recipient), 4 Dec 2015
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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Arthroscopy & Arthroplasty Utrecht Courses 2022
Rob P.A. Janssen (Organiser)
4 Jul 2022 → 8 Jul 2022Activity: Participating in or organising an event types › Workshop, seminar, course or exhibition › Professional
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Voorste kruisbandletsels bij kinderen
Rob P.A. Janssen (Speaker)
24 Jun 2022Activity: Talk or presentation types › Keynote talk › Scientific
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Return to performance after anterior cruciate ligament reconstruction: graft biology
Rob P.A. Janssen (Speaker)
15 Jun 2022Activity: Talk or presentation types › Keynote talk › Scientific
Press / Media
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Eindhoven University of Technology Postdoc Association Has the Postdoc Community at Heart
Maria Pastrama-Mastnak & B. Fitzgerald
11/12/21
1 item of Media coverage
Press/Media: Expert Comment
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TU/e Postdoc Association has postdoc community at heart
Maria Pastrama-Mastnak & B. Fitzgerald
10/12/21
1 item of Media coverage
Press/Media: Expert Comment
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-Eindhoven University of Technology: Major EU grants for groundbreaking research into scoliosis and transplant organ rejection
23/04/21
1 item of Media coverage
Press/Media: Expert Comment
Impacts
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Bone Function and Structure
Evelien Arts-Arts (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
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Bone Tissue Engineering
Evelien Arts-Arts (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
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Intervertebral Disc
Evelien Arts-Arts (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
Student theses
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3D human osteoblast - osteoclast in vitro co-culture
Author: Remmers, S. & Mayer, D., 2019Supervisor: Remmers, S. (Supervisor 1), Melke, J. (Supervisor 1), Hofmann, S. (Supervisor 1), Ito, K. (Supervisor 1) & Teuschl, A. (External person) (Supervisor 2)
Student thesis: Master
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3D reconstruction of coronary artery centerlines from two 2D angiography-based planar projections
Author: Berendsen, A. J., 11 Oct 2021Supervisor: van de Vosse, F. N. (Supervisor 1), van 't Veer, M. (Supervisor 2), van Rietbergen, B. (Supervisor 2) & Bakker, L. M. M. L. (Supervisor 2)
Student thesis: Master
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A 3D co-culture model of mesenchymal stem cells and endothelial cells to promote vascularization and osteogenesis in bone tissue engineering
Author: Cramer, E., 29 Nov 2018Supervisor: Melke, J. (Supervisor 1) & Hofmann, S. (Supervisor 2)
Student thesis: Master