Projects per year
Organisation profile
Introduction / mission
Our mission is to develop innovative technological concepts and fabrication methods for microsystems for a wide range of applications. Our concepts are often inspired by biology, and our microsystems are often applied to understand biological processes that are important for health and disease.
Highlighted phrase
Developing life-enhancing applications through research at the micro-scale
Organisation profile
We develop innovative technological concepts and fabrication methods by carrying out research in our Microfab/lab, often in collaboration with industrial, biomedical, or clinical partners. Practical applications of the group’s research range from organ-on-a-chip systems for cancer and brain research, point-of-care diagnostics, wearable health sensors, water and air quality monitoring and purification, lithography machines, displays, and brain-inspired computing, to soft microrobotics.
The section is structured around the senior scientists Jaap den Toonder (also head of the section), Regina Luttge, Hans Wyss, Yoeri van de Burgt and Erik Homburg, who collectively hold the expertise that defines the scientific identity of the section:
- Jaap den Toonder: microfluidics, micromechanics, organ-on-a-chip
- Regina Luttge: neuro-nanoscale engineering
- Hans Wyss: microfluidics, soft-matter
- Yoeri van de Burgt: organic devices for brain-inspired (neuromorphic) computing
- Erik Homburg: Engineering design
Fingerprint
Collaborations and top research areas from the last five years
Profiles
-
Gülden Akçay
- Mechanical Engineering, Microsystems - Doctoral Candidate
- Mechanical Engineering, Group Luttge - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
-
Kalpit Bakal
- Mechanical Engineering, Microsystems - Doctoral Candidate
- Mechanical Engineering, Group Wyss - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
-
Alex J. Bastiaens
- Mechanical Engineering, Microsystems - Business Developer
Person: OBP : Supportive and management staff
-
DEVELOPMENT OF NOVEL ASSESSMENTS FOR INDOOR AIR QUALITY MONITORING AND IMPACT ON CHILDREN'S HEALTH 101057510
Wyss, H. M. (Project Manager), Taghipour, M. (Project member) & Fiore, A. (Project member)
1/10/23 → 30/09/27
Project: Third tier
-
CRT-OND-BayesBrain: The World's First Brain-on-Chip AI Computer
de Vries, A. (Project Manager), Sijbesma, R. P. (Project member), Adamiat, S. (Project member) & Kouw, W. (Project member)
1/10/21 → 31/03/26
Project: First tier
-
bOne metaStatis chip with microphysiological Circulation for cAncer pRofiling LSHI22004
den Toonder, J. M. J. (Project Manager)
1/04/23 → 31/12/24
Project: Third tier
Research output
-
All Organic Fully Integrated Neuromorphic Crossbar Array
Kazemzadeh, S., Stevens, T. & van de Burgt, Y. (Corresponding author), 22 Feb 2025, (E-pub ahead of print) In: Advanced Electronic Materials. XX, X, 2500054.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
A novel kinetic model estimating the urea concentration in plasma during non-invasive sweat-based monitoring in hemodialysis
Yin, X. (Corresponding author), Adelaars, S., Peri, E., Pelssers, E., den Toonder, J. M. J., Bouwman, R. A., van de Kerkhof, D. H. & Mischi, M., 18 Mar 2025, In: Frontiers in Physiology. 16, 12 p., 1547117.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
A personalized model and optimization strategy for estimating blood glucose concentrations from sweat measurements
Yin, X. (Corresponding author), Peri, E., Pelssers, E., den Toonder, J. M. J., Klous, L., Daanen, H. & Mischi, M., Jun 2025, In: Computer Methods and Programs in Biomedicine. 265, 11 p., 108743.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile
Equipment
-
Microfab/Lab
Sahebali, S. (Manager) & ter Elst, W. B. M. (Manager)
Mechanical EngineeringFacility/equipment: Research lab
Datasets
-
Source data for the publication: Curved Surfaces Induce Metachronal Motion of Microscopic Magnetic Cilia
Cui, Z. (Creator), Ul Islam, T. (Creator), Wang, Y. (Creator) & den Toonder, J. M. J. (Creator), 4TU.Centre for Research Data, 15 Nov 2024
DOI: 10.4121/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7, https://data.4tu.nl/datasets/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7 and one more link, https://data.4tu.nl/datasets/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7/1 (show fewer)
Dataset
-
Source data for the publication: Enhancement of microalgae growth using magnetic artificial cilia
Verburg, T. H. C. M. (Creator), Schaap, A. (Creator), Zhang, S. (Creator), den Toonder, J. (Creator) & Wang, Y. (Creator), 4TU.Centre for Research Data, 15 Nov 2024
DOI: 10.4121/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc, https://data.4tu.nl/datasets/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc and one more link, https://data.4tu.nl/datasets/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc/1 (show fewer)
Dataset
-
Source data for the publication: A Cell Pre-Wrapping Seeding Technique for Hydrogel-Based Tubular Organ-On-A-Chip
Nie, J. (Creator), Lou, S. (Creator), Pollet, A. (Creator), van Vegchel, M. (Creator), Bouten, C. V. C. (Creator) & den Toonder, J. M. J. (Creator), 4TU.Centre for Research Data, 15 Nov 2024
DOI: 10.4121/6b6afa04-cf9c-4273-8150-8eb34c22b138, https://data.4tu.nl/datasets/6b6afa04-cf9c-4273-8150-8eb34c22b138 and one more link, https://data.4tu.nl/datasets/6b6afa04-cf9c-4273-8150-8eb34c22b138/1 (show fewer)
Dataset
Prizes
-
-
Best Journal Paper Award
Demircan Yalçin, Y. (Recipient), 4 Jun 2021
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
-
Best poster presentation prize
Jouy Bar, M. (Recipient), Ballerini, M. (Recipient), Nezi, L. (Recipient) & Rasponi, M. (Recipient), 10 Sept 2020
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
-
European Organ-on-Chip Society (EUROoCS) (External organisation)
Akçay, G. (Member)
Jan 2020 → …Activity: Membership types › Membership of committee › Scientific
-
human Organ and Disease Model Technologies (hDMT) (External organisation)
Akçay, G. (Member)
21 Oct 2019Activity: Membership types › Membership of committee › Scientific
-
Member Scientific Advisory Panel
van de Burgt, Y. (Consultant)
1 Oct 2017 → …Activity: Consultancy types › Consultancy › Scientific
Press/Media
-
AI with a human touch: regulation for co-creation
IJsselsteijn, W. A., Lüttge, R. & Behrendt, F.
6/11/23
1 item of Media coverage
Press/Media: Expert Comment
-
New Findings from Eindhoven University of Technology in the Area of Science Published (Miniaturized metachronal magnetic artificial cilia)
Wang, T., Cui, Z., den Toonder, J. M. J. & Wang, Y.
7/09/23
1 item of Media coverage
Press/Media: Expert Comment
-
Synapses and Silicon: Exploring the Intersection of AI and Neuroscience EAISI AI Symposium
Krauhausen, I.
25/03/23
1 item of Media coverage
Press/Media: Expert Comment
Student theses
-
3D printing of microfluidic chips with different modules for point-of-care testing applications
Ojha, A. (Author), den Toonder, J. M. J. (Supervisor 1), Bernards, J. (External coach) & Planken, K. L. (External coach), 30 Aug 2019Student thesis: Master
File -
A brain chip to investigate neurite outgrowth by trapping cell-laden hydrogel beads in microsieves
Labeur, T. (Author), Bouten, C. (Supervisor 1), Luttge, R. (Supervisor 2), Kurniawan, N. (Supervisor 2) & Bastiaens, A. (Supervisor 2), 29 Aug 2019Student thesis: Master
-
Active components for micro-fluidic manipulation
van Uden, M. J. (Author), den Toonder, J. M. J. (Supervisor 1) & Wimberger-Friedl, R. (External coach), 2009Student thesis: Master