Projects per year
Organization profile
Introduction / mission
Our mission is to develop innovative technological concepts and fabrication methods for microsystems for a wide range of applications. Our concepts are often inspired by biology, and our microsystems are often applied to understand biological processes that are important for health and disease.
Highlighted phrase
Developing life-enhancing applications through research at the micro-scale
Organisational profile
We develop innovative technological concepts and fabrication methods by carrying out research in our Microfab/lab, often in collaboration with industrial, biomedical, or clinical partners. Practical applications of the group’s research range from organ-on-a-chip systems for cancer and brain research, point-of-care diagnostics, wearable health sensors, water and air quality monitoring and purification, lithography machines, displays, and brain-inspired computing, to soft microrobotics.
The section is structured around the senior scientists Jaap den Toonder (also head of the section), Regina Luttge, Hans Wyss, Yoeri van de Burgt and Erik Homburg, who collectively hold the expertise that defines the scientific identity of the section:
- Jaap den Toonder: microfluidics, micromechanics, organ-on-a-chip
- Regina Luttge: neuro-nanoscale engineering
- Hans Wyss: microfluidics, soft-matter
- Yoeri van de Burgt: organic devices for brain-inspired (neuromorphic) computing
- Erik Homburg: Engineering design
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Network
Profiles
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Eva A. van Aalen
- Mechanical Engineering, Group Den Toonder - University Researcher
- Biomedical Engineering, Protein Engineering - University Researcher
Person: OWP : University Teacher / Researcher
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Gülden Akçay
- Mechanical Engineering, Group Luttge - Doctoral Candidate
- Mechanical Engineering, Microsystems - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Kalpit Bakal
- Mechanical Engineering, Microsystems - Doctoral Candidate
- Mechanical Engineering, Group Wyss - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
Projects
- 1 Finished
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Magnetic control of micro-particles and integrated micro-actuators for high precision handheld diagnostics
den Toonder, J. M. J. & Shanko, E.
1/11/16 → 31/10/20
Project: Research direct
Research output
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A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?
Rahmanian, M., Sartipzadeh Hematabad, O., Askari, E., Shokati, F., Bakhshi, A., Moghadam, S., Olfatbakhsh, A., Al Sadat Hashemi, E., Khorsand Ahmadi, M., Morteza Naghib, S., Sinha, N., Tel, J., Eslami Amirabadi, H., den Toonder, J. M. J. & Majidzadeh-A, K., May 2023, In: Journal of Advanced Research. 47, X, p. 105-121 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus) -
A versatile artificial skin platform for sweat sensor development
Moonen, E. J. M., ul Islam, T., van Kemenade, S., Pelssers, E., Heikenfeld, J. & den Toonder, J. M. J., 7 May 2023, In: Lab on a Chip. 23, 9, p. 2268-2275 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Barcode demultiplexing of nanopore sequencing raw signals by unsupervised machine learning
Papetti, D. M., Spolaor, S., Nazari, I., Tirelli, A., Leonardi, T., Caprioli, C., Besozzi, D., Vlachou, T., Pelicci, P. G., Cazzaniga, P. & Nobile, M. S., 27 Apr 2023, In: Frontiers in Bioinformatics. 3, 11 p., 1067113.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Downloads (Pure)
Equipment
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Microfab/Lab
Sheen Sahebali (Manager) & W.B.M. ter Elst (Manager)
Mechanical EngineeringFacility/equipment: Research lab
Datasets
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Supporting Data for Enhancement-mode PEDOT:PSS Organic Electrochemical Transistors using Molecular De-doping
Janssen, R. A. J. (Contributor), Keene, S. T. (Contributor), Zakhidov, D. (Contributor), Weijtens, C. H. L. (Contributor), van der Pol, T. P. A. (Contributor), Salleo, A. (Contributor) & van de Burgt, Y. B. (Contributor), 4TU.Centre for Research Data, 30 Aug 2021
DOI: 10.4121/16535400
Dataset
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Source data for the publication: Anti-Biofouling and Self-Cleaning Surfaces Featured with Magnetic Artificial Cilia
Zhang, S. (Contributor), Zuo, P. (Contributor), Wang, Y. (Contributor), Onck, P. (Contributor), den Toonder, J. M. J. (Contributor) & den Toonder, J. M. J. (Contributor), 4TU.Centre for Research Data, 30 May 2022
DOI: 10.4121/19915330
Dataset
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Microfluidic Models of Metastasis: In vitro approaches to study the tumor microenvironment - supplementary design and video files
Sleeboom, J. J. F. (Creator), Sahlgren, C. M. (Creator) & den Toonder, J. M. J. (Creator), 4TU.Centre for Research Data, 21 Aug 2020
DOI: 10.4121/uuid:08ac69b6-6430-4ffa-a33e-40da88821dc6
Dataset
Prizes
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Best Journal Paper Award
Demircan Yalçin, Yagmur (Recipient), 4 Jun 2021
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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Best poster presentation prize
Jouy Bar, Mohammad (Recipient), Ballerini, Mattia (Recipient), Nezi, Luigi (Recipient) & Rasponi, Marco (Recipient), 10 Sept 2020
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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European Organ-on-Chip Society (EUROoCS) (External organisation)
Gülden Akçay (Member)
Jan 2020 → …Activity: Membership types › Membership of committee › Scientific
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human Organ and Disease Model Technologies (hDMT) (External organisation)
Gülden Akçay (Member)
21 Oct 2019Activity: Membership types › Membership of committee › Scientific
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Member Scientific Advisory Panel
Yoeri van de Burgt (Consultant)
1 Oct 2017 → …Activity: Consultancy types › Consultancy › Scientific
Press/Media
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Research on Gels Research Published by a Researcher at Eindhoven University of Technology (Single Hydrogel Particle Mechanics and Dynamics Studied by Combining Capillary Micromechanics with Osmotic Compression)
22/03/23
1 item of Media coverage
Press/Media: Expert Comment
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Sweet way to study blood vessels near tumors 4 April
4/04/22
2 items of Media coverage
Press/Media: Expert Comment
Student theses
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3D printing of microfluidic chips with different modules for point-of-care testing applications
Author: Ojha, A., 30 Aug 2019Supervisor: den Toonder, J. M. J. (Supervisor 1), Bernards, J. (External person) (External coach) & Planken, K. L. (External coach)
Student thesis: Master
File -
A brain chip to investigate neurite outgrowth by trapping cell-laden hydrogel beads in microsieves
Author: Labeur, T., 29 Aug 2019Supervisor: Bouten, C. (Supervisor 1), Luttge, R. (Supervisor 2), Kurniawan, N. (Supervisor 2) & Bastiaens, A. (Supervisor 2)
Student thesis: Master
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Active components for micro-fluidic manipulation
Author: van Uden, M. J., 2009Supervisor: den Toonder, J. M. J. (Supervisor 1) & Wimberger-Friedl, R. (External person) (External coach)
Student thesis: Master