• Het Kranenveld, Helix (STO 4.33)

    Eindhoven

    Netherlands

  • P.O. Box 513, Helix (STO 4.33)

    5600 MB Eindhoven

    Netherlands

Organization profile

Introduction / mission

How far can we push chemical self-assembly? Bridging the gap between life sciences and materials science, using organic chemistry and polymer chemistry. 

Highlighted phrase

Exploration of supramolecular systems and materials

Organisational profile

At the Macro Organic Chemistry group we educate young students to become independent scientists and make them experienced researchers in the design, synthesis, characterization and possible applications of complex molecular systems with unconventional properties. Our research addresses the challenging question “How far can we push chemical self-assembly?”. This ranges from detailed mechanistic (kinetic) investigations on the self-assembly processes of various molecular structures (e.g. the formation of ordered arrays, under thermodynamic control as well as through kinetic experiments) to the design, non-covalent synthesis and use of artificial mimics of enzymes and extracellular matrices. Our group is part of the overarching research group for Molecular Science and Technology.

From the start in 1991, our research has been focused on the design, synthesis, characterization and possible applications of new functional molecular architectures. Over the years we have worked on dendrimers, semi-conducting oligomers/polymers and several supramolecular units, with chirality as a muse. In the course of time, our focus has shifted towards the synthesis and study of complex molecular systems and in 2007 our group became the founding father of the Institute of Complex Molecular Systems (ICMS) at TU/e. More recently, a renewed interest in functional supramolecular materials for electronics and biomedical engineering has underpinned the relevance of our knowledge in the design and synthesis of molecular units that self-assemble in a controlled way, producing materials ordered at the mesoscale. 

In our current research we aim at closing the gap between organic chemistry, polymer chemistry and chemical biology by applying well-controlled supramolecular chemistry protocols. Central to this is our concept of multi-step non-covalent synthesis of molecular systems, using well-defined small and large molecules. We thus synthesize and study novel artificial molecular systems where the position of all molecules in the system can be controlled with respect to time and space. To arrive at dynamic functionalties of these molecular systems, we investigate the response to external stimuli both experimentally and theoretically.

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Research Output 1972 2019

DNA-functionalized supramolecular polymers: dynamic multicomponent assemblies with emergent properties

Wijnands, S. P. W., Meijer, E. W. & Merkx, M., 1 Jan 2019, In : Bioconjugate Chemistry.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Polymers
DNA
Hybrid systems

Functional supramolecular materials : fundamentals, copolymers and applications

Adelizzi, B., 7 Mar 2019, Eindhoven: Technische Universiteit Eindhoven. 184 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Insights into the kinetics of supramolecular copolymerization in water

Lafleur, R., Schoenmakers, S., Madhikar, P., Bochicchio, D., Baumeier, B., Palmans, A., Pavan, G. & Meijer, B., 2019, (Accepted/In press) In : Macromolecules.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Copolymerization
Polymers
Kinetics
Water
Monomers

Prizes

NWO Veni Award : Self-oscillating surfaces

Ghislaine Vantomme (Recipient), 2017

Recognition: NWOVeniScientific

sunlight
cleaning
membranes
liquids

NWO Vidi Award : Adaptive materials with molecular light switches

Ilja Voets (Recipient), 2014

Recognition: NWOVidiScientific

Switches
Transparency
Elasticity

Activities 1992 2010

  • 10 Editorial activity
  • 2 Membership of board
  • 2 Membership of committee
  • 1 Contributed talk

Chemical Science (Journal)

E.W. (Bert) Meijer (Editorial board member)
20102015

Activity: Publication peer-review and editorial work typesEditorial activityScientific

Journal of the American Chemical Society (Journal)

E.W. (Bert) Meijer (Editorial board member)
20102016

Activity: Publication peer-review and editorial work typesEditorial activityScientific

DSM (External organisation)

E.W. (Bert) Meijer (Member)
20062012

Activity: Membership typesMembership of boardScientific

Press / Media

New fluorescent polymer makes deformation visible

Hande Cingil

13/08/15

1 item of media coverage

Press/Media: Expert Comment

Student theses

Bioactivation of electrospun UPy-based supramolecular polymer meshes: towards an improved treatment of pelvic floor dysfunctions

Author: Arts, B., 18 Dec 2017

Supervisor: Dankers, P. (Supervisor 1), Zaccaria, S. (Supervisor 2) & Meijer, B. (Supervisor 2)

Student thesis: Master

Block copolymers and crystallinity: pushing phase-separation to its limits

Author: Lamers, B., 22 Feb 2017

Supervisor: van Genabeek, B. (Supervisor 1), Palmans, A. (Supervisor 2) & Meijer, E. (Supervisor 2)

Student thesis: Master

File

Complex coacervate core micelles containing poly(vinyl alcohol) for anti-icing applications

Author: Sproncken, C., Apr 2017

Supervisor: Voets, I. (Supervisor 1), Suris Valls, R. (Supervisor 2) & Tuinier, R. (Supervisor 2)

Student thesis: Master