Department of Biomedical Engineering

Research Output

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Review article
2020

Cellular geometry sensing at different length scales and its implications for scaffold design

Werner, M., Kurniawan, N. A. & Bouten, C. V. C., 21 Feb 2020, In : Materials. 13, 4, 18 p., 963.

Research output: Contribution to journalReview articleAcademicpeer-review

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12 Downloads (Pure)
Open Access
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10 Downloads (Pure)

Small-molecule modulation of p53 protein-protein interactions

Kuusk, A., Boyd, H., Chen, H. & Ottmann, C., 1 Jan 2020, (Accepted/In press) In : Biological Chemistry.

Research output: Contribution to journalReview articleAcademicpeer-review

2019

Adaptive polymeric assemblies for applications in biomimicry and nanomedicine

Altay, Y., Che, H., Cao, S., Abdelmohsen, L. & van Hest, J., 11 Nov 2019, In : Biomacromolecules. 20, 11, p. 4053-4064 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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1 Citation (Scopus)
25 Downloads (Pure)

Allosteric small molecule modulators of nuclear receptors

Meijer, F. A., Leijten-van de Gevel, I. A., de Vries, R. M. J. M. & Brunsveld, L., 5 Apr 2019, In : Molecular and Cellular Endocrinology. 485, p. 20-34 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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6 Citations (Scopus)
154 Downloads (Pure)

ATP-mediated transient behavior of stomatocyte nanosystems

Che, H., Zhu, J., Song, S., Mason, A. F., Cao, S., Pijpers, I. A. B., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 9 Sep 2019, In : Angewandte Chemie - International Edition. 58, 37, p. 13113-13118 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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3 Citations (Scopus)
2 Downloads (Pure)

Bone-adhesive materials: clinical requirements, mechanisms of action, and future perspective

Sánchez-Fernández, M. J., Hammoudeh, H., Félix Lanao, R. P., van Erk, M., van Hest, J. C. M. & Leeuwenburgh, S. C. G., 22 Feb 2019, In : Advanced Materials Interfaces. 6, 4, 11 p., 1802021.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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3 Citations (Scopus)
16 Downloads (Pure)

Cats or CAT scans: transfer learning from natural or medical image source data sets?

Cheplygina, V., Mar 2019, In : Current Opinion in Biomedical Engineering. 9, p. 21-27 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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2 Citations (Scopus)
28 Downloads (Pure)

Cell-free microcompartmentalised transcription-translation for the prototyping of synthetic communication networks

Dubuc, E., Pieters, P. A., van der Linden, A. J., van Hest, J. C. M., Huck, W. T. S. & de Greef, T. F. A., 1 Aug 2019, In : Current Opinion in Biotechnology. 58, p. 72-80 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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8 Citations (Scopus)
67 Downloads (Pure)

Clinical candidates modulating protein-protein interactions: the fragment-based experience

Valenti, D., Hristeva, S., Tzalis, D. & Ottmann, C., 1 Apr 2019, In : European Journal of Medicinal Chemistry. 167, p. 76-95 20 p.

Research output: Contribution to journalReview articleAcademicpeer-review

2 Citations (Scopus)
1 Downloads (Pure)

Decoding the PTM-switchboard of Notch

Antfolk, D., Antila, C., Kemppainen, K., Landor, S. K. J. & Sahlgren, C., 1 Dec 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 12, 21 p., 118507.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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10 Downloads (Pure)

DNA-functionalized supramolecular polymers: dynamic multicomponent assemblies with emergent properties

Wijnands, S. P. W., Meijer, E. W. & Merkx, M., 17 Jul 2019, In : Bioconjugate Chemistry. 30, 7, p. 1905-1914 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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3 Citations (Scopus)
40 Downloads (Pure)

Emerging modes-of-action in drug discovery

Valeur, E., Narjes, F., Ottmann, C. & Plowright, A. T., 1 Oct 2019, In : MedChemComm. 10, 9, p. 1550-1568 19 p.

Research output: Contribution to journalReview articleAcademicpeer-review

1 Citation (Scopus)

Lipid nanoparticle technology for clinical translation of siRNA therapeutics

Kulkarni, J. A., Witzigmann, D., Chen, S., Cullis, P. R. & van der Meel, R., 17 Sep 2019, In : Accounts of Chemical Research. 52, 9, p. 2435-2444 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

3 Citations (Scopus)

Modulating protein–protein interaction networks in protein homeostasis

Zhong, M., Lee, G. M., Sijbesma, E., Ottmann, C. & Arkin, M. R., 1 Jun 2019, In : Current Opinion in Chemical Biology. 50, p. 55-65 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

4 Citations (Scopus)
3 Downloads (Pure)

Nanoimmunotherapy to treat ischaemic heart disease

Duivenvoorden, R., Senders, M. L., van Leent, M. M. T., Pérez-Medina, C., Nahrendorf, M., Fayad, Z. A. & Mulder, W. J. M., Jan 2019, In : Nature Reviews. Cardiology. 16, 1, p. 21-32 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

3 Citations (Scopus)

Rotating magnetic particles for lab-on-chip applications-a comprehensive review

Moerland, C. P., van IJzendoorn, L. J. & Prins, M. W. J., 21 Mar 2019, In : Lab on a Chip. 19, 6, p. 919-933 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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6 Citations (Scopus)
33 Downloads (Pure)

Smart cancer nanomedicine

van der Meel, R., Sulheim, E., Shi, Y., Kiessling, F., Mulder, W. & Lammers, T., 6 Nov 2019, In : Nature Nanotechnology. 14, 11, p. 1007–1017 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

14 Citations (Scopus)
1 Downloads (Pure)

Super-resolution microscopy as a powerful tool to study complex synthetic materials

Pujals, S., Feiner-Gracia, N., Delcanale, P., Voets, I. & Albertazzi, L., 1 Feb 2019, In : Nature Reviews Chemistry. 3, 2, p. 68-84 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

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14 Citations (Scopus)
23 Downloads (Pure)

Super-resolution microscopy for nanomedicine research

Pujals, S. & Albertazzi, L., 24 Sep 2019, In : ACS Nano. 13, 9, p. 9707-9712 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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3 Citations (Scopus)
19 Downloads (Pure)

Therapeutic targeting of trained immunity

Mulder, W. J. M., Ochando, J., Joosten, L. A. B., Fayad, Z. A. & Netea, M. G., 9 Apr 2019, In : Nature Reviews Drug Discovery. 18, 7, p. 553-566 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

20 Citations (Scopus)
2018

14-3-3: A case study in ppi modulation

Ballone, A., Centorrino, F. & Ottmann, C., 8 Jun 2018, In : Molecules. 23, 6, 14 p., 1386.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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7 Citations (Scopus)
43 Downloads (Pure)

Integrating immunology and microfluidics for single immune cell analysis

Sinha, N., Subedi, N. & Tel, J., 16 Oct 2018, In : Frontiers in Immunology. 9, 16 p., 2373.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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3 Citations (Scopus)
141 Downloads (Pure)

Investigating supramolecular systems using Förster resonance energy transfer

Teunissen, A. J. P., Pérez-Medina, C., Meijerink, A. & Mulder, W. J. M., 21 Sep 2018, In : Chemical Society Reviews. 47, 18, p. 7027-7044 18 p.

Research output: Contribution to journalReview articleAcademicpeer-review

17 Citations (Scopus)

Mechanobiology of the cell–matrix interplay: catching a glimpse of complexity via minimalistic models

Kurniawan, N. A. & Bouten, C. V. C., 1 Apr 2018, In : Extreme Mechanics Letters. 20, p. 59-64 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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5 Citations (Scopus)
101 Downloads (Pure)

Metastasis in context: modeling the tumor microenvironment with cancer-on-a-chip approaches

Sleeboom, J. J. F., Amirabadi, H. E., Nair, P., Sahlgren, C. M. & Den Toonder, J. M. J., 1 Mar 2018, In : Disease Models & Mechanisms. 11, 3, 17 p., 033100.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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22 Citations (Scopus)
184 Downloads (Pure)

Multi-omics profiling of the tumor microenvironment: Paving the way to precision immuno-oncology

Finotello, F. & Eduati, F., 5 Oct 2018, In : Frontiers in Oncology. 8, OCT, 9 p., 430.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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12 Citations (Scopus)
57 Downloads (Pure)

Polymers at the interface with biology

Deming, T. J., Klok, H. A., Armes, S. P., Becker, M. L., Champion, J. A., Chen, E. Y. X., Heilshorn, S. C., van Hest, J. C. M., Irvine, D. J., Johnson, J. A., Kiessling, L. L., Maynard, H. D., De La Cruz, M. O., Sullivan, M. O., Tirrell, M. V., Anseth, K. S., Lecommandoux, S., Percec, S., Zhong, Z. & Albertsson, A. C., 13 Aug 2018, In : Biomacromolecules. 19, 8, p. 3151-3162 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
3 Citations (Scopus)
1 Downloads (Pure)

Self-assembled nanoreactors based on peptides and proteins

Timmermans, S. B. P. E. & van Hest, J. C. M., 1 May 2018, In : Current Opinion in Colloid and Interface Science. 35, p. 26-35 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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14 Citations (Scopus)
77 Downloads (Pure)

Synthetic immune niches for cancer immunotherapy

Weiden, J., Tel, J. & Figdor, C. G., 1 Mar 2018, In : Nature Reviews Immunology. 18, 3, p. 212-219 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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47 Citations (Scopus)
417 Downloads (Pure)

The future of heart valve replacement: recent developments and translational challenges for heart valve tissue engineering

Fioretta, E. S., Dijkman, P. E., Emmert, M. Y. & Hoerstrup, S. P., 1 Jan 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 1, p. e323-e335

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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17 Citations (Scopus)
799 Downloads (Pure)

The hallmarks of living systems: Towards creating artificial cells

Amy Yewdall, N., Mason, A. F. & Van Hest, J. C. M., 6 Oct 2018, In : Interface Focus. 8, 5, 15 p., 20180023.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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11 Citations (Scopus)
65 Downloads (Pure)
2017

14-3-3 adaptor protein-protein interactions as therapeutic targets for CNS diseases

Kaplan, A., Ottmann, C. & Fournier, A. E., 1 Nov 2017, In : Pharmacological Research. 125, part B, p. 114-121 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

16 Citations (Scopus)
1 Downloads (Pure)

Bio-inks for 3D bioprinting: recent advances and future prospects

Donderwinkel, I., van Hest, J. C. M. & Cameron, N. R., 20 Aug 2017, In : Polymer Chemistry. 8, 31, p. 4451-4471 21 p.

Research output: Contribution to journalReview articleAcademicpeer-review

62 Citations (Scopus)

Current challenges in translating tissue-engineered heart valves

Stassen, O. M. J. A., Muylaert, D. E. P., Bouten, C. V. C. & Hjortnaes, J., 1 Sep 2017, In : Current Treatment Options in Cardiovascular Medicine. 19, 9, 13 p., 71.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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7 Citations (Scopus)
53 Downloads (Pure)

From supramolecular polymers to multi-component biomaterials

Goor, O. J. G. M., Hendrikse, S. I. S., Dankers, P. Y. W. & Meijer, E. W., 7 Nov 2017, In : Chemical Society Reviews. 46, 21, p. 6621-6637 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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81 Citations (Scopus)
222 Downloads (Pure)

How not to drown in data: a guide for biomaterial engineers

Vasilevich, A. S., Carlier, A., de Boer, J. & Singh, S., Aug 2017, In : Trends in Biotechnology. 35, 8, p. 743-755 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

11 Citations (Scopus)
2 Downloads (Pure)

Joining forces: the chemical biology–medicinal chemistry continuum

Plowright, A. T., Ottmann, C., Arkin, M., Auberson, Y. P., Timmerman, H. & Waldmann, H., 21 Sep 2017, In : Cell Chemical Biology. 24, 9, p. 1058-1065 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

9 Citations (Scopus)

Subthalamic nucleus deep brain stimulation: Basic concepts and novel perspectives

Hamani, C., Florence, G., Heinsen, H., Plantinga, B. R., Temel, Y., Uludag, K., Alho, E., Teixeira, M. J., Amaro, E. & Fonoff, E. T., 1 Sep 2017, In : eNeuro. 4, 5, e0140-17.2017.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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25 Citations (Scopus)
35 Downloads (Pure)

Tailored approaches in drug development and diagnostics: from molecular design to biological model systems

Sahlgren, C. M., Meinander, A., Zhang, H., Cheng, F., Preis, M., Xu, C., Salminen, T. A., Toivola, D. M., Abankwa, D., Rosling, A., Karaman, D. Ş., Salo-Ahen, O. M. H., Österbacka, R., Eriksson, J. E., Willför, S., Petre, I., Peltonen, J., Leino, R., Johnson, M., Rosenholm, J. & 1 others, Sandler, N., 8 Nov 2017, In : Advanced Healthcare Materials. 6, 21, p. 1-34 1700258.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
14 Citations (Scopus)

Tumour-vessel-on-a-chip models for drug delivery

Caballero, D., Blackburn, S. M., De Pablo, M., Samitier, J. & Albertazzi, L., 1 Jan 2017, In : Lab on a Chip. 17, 22, p. 3760-3771 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

21 Citations (Scopus)

Vascular mechanobiology: towards control of in situ regeneration

van Haaften, E. E., Bouten, C. V. C. & Kurniawan, N. A., 3 Jul 2017, In : Cells. 6, 3, p. 1-24 19.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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159 Downloads (Pure)
2016

7 T renal MRI: challenges and promises

de Boer, A., Hoogduin, J. M., Blankestijn, P. J., Li, X., Luijten, P. R., Metzger, G. J., Raaijmakers, A. J. E., Umutlu, L., Visser, F. & Leiner, T., Jun 2016, In : Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA). 29, 3, p. 417-433 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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7 Citations (Scopus)
50 Downloads (Pure)

Adipose tissue-derived stem cells in regenerative medicine

Frese, L., Dijkman, P. E. & Hoerstrup, S. P., 1 Jul 2016, In : Transfusion Medicine and Hemotherapy. 43, 4, p. 268-274 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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119 Citations (Scopus)
118 Downloads (Pure)

Heart valve replacements with regenerative capacity

Dijkman, P. E., Fioretta, E. S., Frese, L., Pasqualini, F. S. & Hoerstrup, S. P., 1 Jul 2016, In : Transfusion Medicine and Hemotherapy. 43, 4, p. 282-290 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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14 Citations (Scopus)
64 Downloads (Pure)

MRI methods for the evaluation of high intensity focused ultrasound tumor treatment: current status and future needs

Hectors, S. J. C. G., Jacobs, I., Moonen, C. T. W., Strijkers, G. J. & Nicolaij, K., 1 Jan 2016, In : Magnetic Resonance in Medicine. 75, 1, p. 302-317 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
26 Citations (Scopus)
1 Downloads (Pure)
2014

Contrast-enhanced T1-mapping MRI for the assessment of myocardial fibrosis

de Graaf, W. L., Vandoorne, K., Arslan, F., Nicolaij, K. & Strijkers, G. J., 2014, In : Current Cardiovascular Imaging Reports. 7, 4, p. 1-12 12 p., 9260.

Research output: Contribution to journalReview articleAcademicpeer-review

2 Citations (Scopus)
1 Downloads (Pure)

Diffusion tensor MRI of the heart : in vivo imaging of myocardial fiber architecture

Froeling, M., Strijkers, G. J., Nederveen, A. J., Chamuleau, S. A. & Luijten, P. R., 2014, In : Current Cardiovascular Imaging Reports. 7, 7, p. 1-11 11 p., 9276.

Research output: Contribution to journalReview articleAcademicpeer-review

13 Citations (Scopus)
1 Downloads (Pure)

Myocardial blood flow quantification from MRI - an image analysis perspective

Zarinabad, N., Chiribiri, A. & Breeuwer, M., 2014, In : Current Cardiovascular Imaging Reports. 7, 1, p. 1-9 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

4 Citations (Scopus)

New developments in paediatric cardiac functional ultrasound imaging

De Korte, C. L., Nillesen, M. M., Saris, A. E. C. M., Lopata, R. G. P., Thijssen, J. M. V. & Kapusta, L., 2014, In : Journal of Medical Ultrasonics. 41, 3, p. 279-290 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

3 Citations (Scopus)