Department of Biomedical Engineering

Research Output 1962 2019

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Review article
2019

Molecular repolarisation of tumour-associated macrophages

van Dalen, F. J., van Stevendaal, M. H. M. E., Fennemann, F. L., Verdoes, M. & Ilina, O., 1 Jan 2019, In : Molecules. 24, 1, 25 p., 9

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
macrophages
Macrophages
Tumors
tumors
Neoplasms
2018
1 Citations

14-3-3: A case study in ppi modulation

Ballone, A., Centorrino, F. & Ottmann, C., 1 Jan 2018, In : Molecules. 23, 6, 14 p., 1386

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
14-3-3 Proteins
Modulation
proteins
modulation
Proteins

Cell-free microcompartmentalised transcription-translation for the prototyping of synthetic communication networks

Dubuc, E., Pieters, P. A., van der Linden, A. J., van Hest, J. C. M., Huck, W. T. S. & de Greef, T. F. A., 2018, (Accepted/In press) In : Current Opinion in Biotechnology. 58, p. 72-80 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Transcription
Telecommunication networks
Communication
Cells
Networks (circuits)

Comparison between in vitro and in vivo cartilage overloading studies based on a systematic literature review

Nickien, M., Heuijerjans, A., Ito, K. & van Donkelaar, C. C., 1 Aug 2018, In : Journal of Orthopaedic Research. 36, 8, p. 2076-2086 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Cartilage
Articular Cartilage
In Vitro Techniques
Osteoarthritis
Cell Survival

Integrating immunology and microfluidics for single immune cell analysis

Sinha, N., Subedi, N. & Tel, J., 16 Oct 2018, In : Frontiers in Immunology. 9, 16 p., 2373

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Single-Cell Analysis
Microfluidics
Allergy and Immunology
Immune System
Point-of-Care Systems
1 Citations

Investigating supramolecular systems using Förster resonance energy transfer

Teunissen, A. J. P., Pérez-Medina, C., Meijerink, A. & Mulder, W. J. M., 21 Sep 2018, In : Chemical Society Reviews. 47, 18, p. 7027-7044 18 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Energy transfer
Medical nanotechnology
Biochemistry
Materials science
Conformations
1 Citations

Mechanobiology of the cell–matrix interplay: catching a glimpse of complexity via minimalistic models

Kurniawan, N. A. & Bouten, C. V. C., 1 Apr 2018, In : Extreme Mechanics Letters. 20, p. 59-64 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Tissue
Tissue regeneration
Biomechanics
Biocompatible Materials
Biomaterials
7 Citations

Metastasis in context: modeling the tumor microenvironment with cancer-on-a-chip approaches

Sleeboom, J. J. F., Amirabadi, H. E., Nair, P., Sahlgren, C. M. & Den Toonder, J. M. J., 1 Mar 2018, In : Disease Models & Mechanisms. 11, 3, 033100

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Tumor Microenvironment
Tumors
Neoplasm Metastasis
Neoplasms
Mechanics
1 Citations

Multi-omics profiling of the tumor microenvironment: Paving the way to precision immuno-oncology

Finotello, F. & Eduati, F., 5 Oct 2018, In : Frontiers in Oncology. 8, OCT, 9 p., 430

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Tumor Microenvironment
Neoplasms
Ecosystem
Immunity
Therapeutics
1 Citations

Polymers at the interface with biology

Deming, T. J., Klok, H. A., Armes, S. P., Becker, M. L., Champion, J. A., Chen, E. Y. X., Heilshorn, S. C., van Hest, J. C. M., Irvine, D. J., Johnson, J. A., Kiessling, L. L., Maynard, H. D., De La Cruz, M. O., Sullivan, M. O., Tirrell, M. V., Anseth, K. S., Lecommandoux, S., Percec, S., Zhong, Z. & Albertsson, A. C., 13 Aug 2018, In : Biomacromolecules. 19, 8, p. 3151-3162 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Polymers
3 Citations

Self-assembled nanoreactors based on peptides and proteins

Timmermans, S. B. P. E. & van Hest, J. C. M., 1 May 2018, In : Current Opinion in Colloid and Interface Science. 35, p. 26-35 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Nanoreactors
Peptides
peptides
proteins
Proteins
20 Citations

Synthetic immune niches for cancer immunotherapy

Weiden, J., Tel, J. & Figdor, C. G., 1 Mar 2018, In : Nature Reviews Immunology. 18, 3, p. 212-219 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Immunotherapy
Immunomodulation
Immunity
Neoplasms
Cancer Vaccines
5 Citations

The future of heart valve replacement: recent developments and translational challenges for heart valve tissue engineering

Fioretta, E. S., Dijkman, P. E., Emmert, M. Y. & Hoerstrup, S. P., 1 Jan 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 1, p. e323-e335

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Heart Valves
Tissue Engineering
Tissue engineering
Heart Valve Diseases
Starters
2 Citations

The hallmarks of living systems: Towards creating artificial cells

Amy Yewdall, N., Mason, A. F. & Van Hest, J. C. M., 6 Oct 2018, In : Interface Focus. 8, 5, 15 p., 20180023

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Artificial Cells
Earth (planet)
Biological Phenomena
Automatic Data Processing
Transplantation
2017
7 Citations

14-3-3 adaptor protein-protein interactions as therapeutic targets for CNS diseases

Kaplan, A., Ottmann, C. & Fournier, A. E., 1 Nov 2017, In : Pharmacological Research. 125, part B, p. 114-121 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

14-3-3 Proteins
Central Nervous System Diseases
Proteins
Therapeutics
Therapeutic Uses
20 Citations

Bio-inks for 3D bioprinting: recent advances and future prospects

Donderwinkel, I., van Hest, J. C. M. & Cameron, N. R., 20 Aug 2017, In : Polymer Chemistry. 8, 31, p. 4451-4471 21 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Bioprinting
Printing
Ink
Polymers
Biocompatible Materials
3 Citations

Current challenges in translating tissue-engineered heart valves

Stassen, O. M. J. A., Muylaert, D. E. P., Bouten, C. V. C. & Hjortnaes, J., 1 Sep 2017, In : Current Treatment Options in Cardiovascular Medicine. 19, 9, 13 p., 71

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Heart Valves
Heart Valve Diseases
Biocompatible Materials
Bioreactors
Complex Mixtures
33 Citations

From supramolecular polymers to multi-component biomaterials

Goor, O. J. G. M., Hendrikse, S. I. S., Dankers, P. Y. W. & Meijer, E. W., 7 Nov 2017, In : Chemical Society Reviews. 46, 21, p. 6621-6637 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Biocompatible Materials
Polymers
Bearings (structural)
Hydrogels
Hydrogel
2 Citations

How to define the hemodynamic significance of an equivocal iliofemoral artery stenosis: review of literature and outcomes of an international questionnaire

de Boer, S. W., Heinen, S. G. H., van den Heuvel, D. A. F., van de Vosse, F. N. & de Vries, J. P. P. M., 1 Dec 2017, In : Vascular. 25, 6, p. 598-608 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Pathologic Constriction
Arteries
Hemodynamics
Arterial Pressure
Surveys and Questionnaires
5 Citations

Joining forces: the chemical biology–medicinal chemistry continuum

Plowright, A. T., Ottmann, C., Arkin, M., Auberson, Y. P., Timmerman, H. & Waldmann, H., 21 Sep 2017, In : Cell Chemical Biology. 24, 9, p. 1058-1065 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Pharmaceutical Chemistry
Joining
Biological systems
Drug Discovery
Medicine
6 Citations

Subthalamic nucleus deep brain stimulation: Basic concepts and novel perspectives

Hamani, C., Florence, G., Heinsen, H., Plantinga, B. R., Temel, Y., Uludag, K., Alho, E., Teixeira, M. J., Amaro, E. & Fonoff, E. T., 1 Sep 2017, In : eNeuro. 4, 5, e0140-17.2017

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Subthalamic Nucleus
Deep Brain Stimulation
Parkinson Disease
Motor Cortex
Neuroimaging
7 Citations

Tailored approaches in drug development and diagnostics: from molecular design to biological model systems

Sahlgren, C. M., Meinander, A., Zhang, H., Cheng, F., Preis, M., Xu, C., Salminen, T. A., Toivola, D. M., Abankwa, D., Rosling, A., Karaman, D. Ş., Salo-Ahen, O. M. H., Österbacka, R., Eriksson, J. E., Willför, S., Petre, I., Peltonen, J., Leino, R., Johnson, M., Rosenholm, J. & 1 othersSandler, N., 8 Nov 2017, In : Advanced Healthcare Materials. 6, 21, p. 1-34 1700258

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Biological Models
Molecular Pathology
Drug delivery
Pharmaceutical Preparations
Pharmacokinetics
3 Citations

The available evidence on demineralised bone matrix in trauma and orthopaedic surgery: a systematic review

van der Stok, J., Hartholt, K. A., Schoenmakers, D. A. L. & Arts, J. J. C., 1 Jul 2017, In : Bone and Joint Research. 6, 7, p. 423-432 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Bone Matrix
Orthopedics
Wounds and Injuries
Manuscripts
Randomized Controlled Trials
4 Citations

Tumour-vessel-on-a-chip models for drug delivery

Caballero, D., Blackburn, S. M., De Pablo, M., Samitier, J. & Albertazzi, L., 1 Jan 2017, In : Lab on a Chip. 17, 22, p. 3760-3771 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Drug delivery
Microfluidics
Tumors
Pharmaceutical Preparations
Neoplasms

Vascular mechanobiology: towards control of in situ regeneration

van Haaften, E. E., Bouten, C. V. C. & Kurniawan, N. A., 3 Jul 2017, In : Cells. 6, 3, p. 1-24 19

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Biophysics
Blood Vessels
Regeneration
Tissue
Tissue engineering
2016
5 Citations

7 T renal MRI: challenges and promises

de Boer, A., Hoogduin, J. M., Blankestijn, P. J., Li, X., Luijten, P. R., Metzger, G. J., Raaijmakers, A. J. E., Umutlu, L., Visser, F. & Leiner, T., Jun 2016, In : Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA). 29, 3, p. 417-433 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Magnetic Resonance Imaging
Kidney
Signal-To-Noise Ratio
Angiography
Sodium
54 Citations

Adipose tissue-derived stem cells in regenerative medicine

Frese, L., Dijkman, P. E. & Hoerstrup, S. P., 1 Jul 2016, In : Transfusion Medicine and Hemotherapy. 43, 4, p. 268-274 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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Regenerative Medicine
Adipose Tissue
Stem Cells
Multipotent Stem Cells
Osteocytes

Current practices and challenges in ruptured abdominal aortic aneurysm repair

't Mannetje, Y. W., Broos, P. P. H. L., van Sambeek, M. R. H. M., Cuypers, P. W. M. & Teijink, J. A. W., 1 Mar 2016, In : Italian Journal of Vascular and Endovascular Surgery. 23, 1, p. 34-45 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Aortic Rupture
Abdominal Aortic Aneurysm
Preoperative Care
Patient Selection
Aneurysm
12 Citations

Heart valve replacements with regenerative capacity

Dijkman, P. E., Fioretta, E. S., Frese, L., Pasqualini, F. S. & Hoerstrup, S. P., 1 Jul 2016, In : Transfusion Medicine and Hemotherapy. 43, 4, p. 282-290 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Heart Valves
Tissue Engineering
Pathologic Constriction
Technology
Incidence
19 Citations

MRI methods for the evaluation of high intensity focused ultrasound tumor treatment: current status and future needs

Hectors, S. J. C. G., Jacobs, I., Moonen, C. T. W., Strijkers, G. J. & Nicolaij, K., 1 Jan 2016, In : Magnetic Resonance in Medicine. 75, 1, p. 302-317 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Neoplasms
Therapeutics
High-Intensity Focused Ultrasound Ablation
Hot Temperature
134 Citations

Silk fibroin as biomaterial for bone tissue engineering

Melke, J., Midha, S., Ghosh, S., Ito, K. & Hofmann, S., Feb 2016, In : Acta Biomaterialia. 31, p. 1-16 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Fibroins
Silk
Biocompatible Materials
Tissue Engineering
Tissue engineering
28 Citations

Standardization of fractional flow reserve measurements

Toth, G. G., Johnson, N. P., Jeremias, A., Pellicano, M., Vranckx, P., Fearon, W. F., Barbato, E., Kern, M. J., Pijls, N. H. J. & De Bruyne, B., 1 Aug 2016, In : Journal of the American College of Cardiology. 68, 7, p. 742-753 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Pressure
Coronary Stenosis
Research
Artifacts
2015
19 Citations

Rationale and design of the fractional flow reserve versus angiography for multivessel evaluation (FAME) 3 trial: a comparison of fractional flow reserve-guided percutaneous coronary intervention and coronary artery bypass graft surgery in patients with multivessel coronary artery disease

Zimmermann, F. M., de Bruyne, B., Pijls, N. H. J., Desai, M., Oldroyd, K. G., Park, S. J., Reardon, M. J., Wendler, O., Woo, J., Yeung, A. C. & Fearon, W. F., 1 Oct 2015, In : American Heart Journal. 170, 4, p. 619-626 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Percutaneous Coronary Intervention
Coronary Artery Bypass
Coronary Artery Disease
Angiography
Transplants
22 Citations

Vascularization mediated by mesenchymal stem cells from bone marrow and adipose tissue : a comparison

Pill, K., Hofmann, S., Redl, H. & Holnthoner, W., 23 Oct 2015, In : Cell Regeneration. 4, 1, 10 p., 8

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Mesenchymal Stromal Cells
Adipose Tissue
Bone Marrow
Bone and Bones
Endothelial Cells
2014
1 Citations

Contrast-enhanced T1-mapping MRI for the assessment of myocardial fibrosis

de Graaf, W. L., Vandoorne, K., Arslan, F., Nicolaij, K. & Strijkers, G. J., 2014, In : Current Cardiovascular Imaging Reports. 7, 4, p. 1-12 12 p., 9260

Research output: Contribution to journalReview articleAcademicpeer-review

Fibrosis
Magnetic Resonance Imaging
Gold
Contrast Media
Heart Diseases
9 Citations

Diffusion tensor MRI of the heart : in vivo imaging of myocardial fiber architecture

Froeling, M., Strijkers, G. J., Nederveen, A. J., Chamuleau, S. A. & Luijten, P. R., 2014, In : Current Cardiovascular Imaging Reports. 7, 7, p. 1-11 11 p., 9276

Research output: Contribution to journalReview articleAcademicpeer-review

Diffusion Magnetic Resonance Imaging
Heart Diseases
Pathology
Wounds and Injuries
4 Citations

Myocardial blood flow quantification from MRI - an image analysis perspective

Zarinabad, N., Chiribiri, A. & Breeuwer, M., 2014, In : Current Cardiovascular Imaging Reports. 7, 1, p. 1-9 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Perfusion
Perfusion Imaging
Contrast Media
Ischemia
Radiation
2 Citations

New developments in paediatric cardiac functional ultrasound imaging

De Korte, C. L., Nillesen, M. M., Saris, A. E. C. M., Lopata, R. G. P., Thijssen, J. M. V. & Kapusta, L., 2014, In : Journal of Medical Ultrasonics. 41, 3, p. 279-290 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Ultrasonography
Pediatrics
Elasticity Imaging Techniques
Radio
Blood Flow Velocity
93 Citations

Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging

Ciccarelli, O., Barkhof, F., Bodini, B., De Stefano, N., Golay, X., Nicolay, K., Pelletier, D., Pouwels, P. J. W., Smith, S. A., Wheeler-Kingshott, C. A. M., Stankoff, B., Yousry, T. & Miller, D. H., 2014, In : The Lancet Neurology. 13, 8, p. 807-822 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Molecular Imaging
Multiple Sclerosis
Microglia
Demyelinating Diseases
Blood-Brain Barrier
2013
58 Citations

Fractional flow reserve to guide coronary revascularization

Pijls, N. H. J., 5 Mar 2013, In : Circulation Journal. 77, 3, p. 561-569 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Pathologic Constriction
Coronary Circulation
Coronary Stenosis
Hyperemia
Angina Pectoris
15 Citations

Intra-aortic balloon pump trials: questions, answers, and unresolved issues

Perera, D., Lumley, M., Pijls, N. & Patel, M. R., 1 Jun 2013, In : Circulation: Cardiovascular Interventions. 6, 3, p. 317-321 5 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Counterpulsation
Cardiogenic Shock
Percutaneous Coronary Intervention
Acute Coronary Syndrome
Shock
2010
14 Citations

Systems biology from micro-organisms to human metabolic diseases: the role of detailed kinetic models

Bakker, B. M., van Eunen, K., Jeneson, J. A. L., van Riel, N. A. W., Bruggeman, F. J. & Teusink, B., 1 Oct 2010, In : Biochemical Society Transactions. 38, 5, p. 1294-1301 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Systems Biology
Metabolic Diseases
Glycolysis
Enzyme kinetics
Inborn Genetic Diseases
2004
58 Citations

Guidance of complex PCI by coronary pressure measurement

Pijls, N. H. J., 1 Sep 2004, In : Heart. 90, 9, p. 1085-1093 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

63 Citations

Laminopathies

Broers, J. L. V., Hutchison, C. J. & Ramaekers, F. C. S., 2004, In : Journal of Pathology. 204, 4, p. 478-488 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Lamins
Nuclear Envelope
Intermediate Filament Proteins
Nuclear Pore
Inborn Genetic Diseases