Department of Biomedical Engineering

Research Output 1962 2019

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Article
2019
1 Citation (Scopus)

On the relationship between dynamic contrast-enhanced ultrasound parameters and the underlying vascular architecture extracted from acoustic angiography

Panfilova, A., Shelton, S. E., Caresio, C., van Sloun, R. J. G., Molinari, F., Wijkstra, H., Dayton, P. A. & Mischi, M., Feb 2019, In : Ultrasound in Medicine and Biology. 45, 2, p. 539-548

Research output: Contribution to journalArticleAcademicpeer-review

angiography
Acoustics
Blood Vessels
Angiography
Perfusion

Optical control of antibody activity using photocleavable bivalent peptide-DNA locks

Wouters, S., Wijker, E. & Merkx, M., 10 May 2019, In : ChemBioChem.

Research output: Contribution to journalArticleAcademicpeer-review

Peptides
Antibodies
DNA
Ligands
Light
1 Citation (Scopus)

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors

Singh, A. A., Schuurman, K., Nevedomskaya, E., Stelloo, S., Linder, S., Droog, M., Kim, Y., Sanders, J., van der Poel, H., Bergman, A. M., Wessels, L. F. A. & Zwart, W., 1 Jan 2019, In : Life Science Alliance. 2, 1, 12 p., e201800115

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Chromatin Immunoprecipitation
tumor
Chromatin
chromatin
Tumors

Pathway Complexity in the Stacking of Imine-linked Macrocycles Related to Two-Dimensional Covalent Organic Frameworks

Wang, S., Chavez, A., Thomas, S., Li, H., Flanders, N., Sun, C., Strauss, M., Chen, L., Markvoort, B., Bredas, J-L. & Dichtel, W., 9 Aug 2019, In : Chemistry of Materials. 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Imines
Personal digital assistants
Bearings (structural)
Monomers
Polymerization

Pathway control in cooperative vs. anti-cooperative supramolecular polymers

Herkert, L., Droste, J., Kartha, K. K., Korevaar, P. A., de Greef, T. F. A., Hansen, M. R. & Fernández, G., 5 Aug 2019, In : Angewandte Chemie - International Edition. 58, 33, p. 11344-11349

Research output: Contribution to journalArticleAcademicpeer-review

File
Polymers
Self assembly
Functional materials
Solubility
Monomers
Artificial Cells
Biochemical Phenomena
Polymers
Membranes
Macromolecules
1 Citation (Scopus)

Predicting breast tumor proliferation from whole-slide images: The TUPAC16 challenge

Veta, M., Heng, Y. J., Stathonikos, N., Bejnordi, B. E., Beca, F., Wollmann, T., Rohr, K., Shah, M. A., Wang, D., Rousson, M., Hedlund, M., Tellez, D., Ciompi, F., Zerhouni, E., Lanyi, D., Viana, M., Kovalev, V., Liauchuk, V., Phoulady, H. A., Qaiser, T. & 13 othersGraham, S., Rajpoot, N., Sjöblom, E., Molin, J., Paeng, K., Hwang, S., Park, S., Jia, Z., Chang, E. I-C., Xu, Y., Beck, A. H., van Diest, P. J. & Pluim, J. P. W., 27 Feb 2019, In : Medical Image Analysis. 54, p. 111-121 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tumors
Breast Neoplasms
Neoplasms
Mitosis
Image analysis
1 Citation (Scopus)

Predictive factors of discordance between the instantaneous wave-free ratio and fractional flow reserve

Dérimay, F., Johnson, N. P., Zimmermann, F. M., Adjedj, J., Witt, N., Hennigan, B., Koo, B. K., Barbato, E., Esposito, G., Trimarco, B., Rioufol, G., Park, S. J., Baptista, S. B., Chrysant, G. S., Leone, A. M., Jeremias, A., Berry, C., De Bruyne, B., Oldroyd, K. G., Pijls, N. H. J. & 1 othersFearon, W. F., 31 Jan 2019, In : Catheterization and Cardiovascular Interventions.

Research output: Contribution to journalArticleAcademicpeer-review

Pathologic Constriction
Heart Rate
Hemodynamics
Gold
Multicenter Studies

Prospective follow-Up of cortical interruptions, bone density, and micro-structure detected on HR-pQCT: A study in patients with rheumatoid arthritis and healthy subjects

Peters, M., van den Bergh, J. P., Geusens, P., Scharmga, A., Loeffen, D., Weijers, R., van Rietbergen, B. & van Tubergen, A., 1 Jun 2019, In : Calcified Tissue International. 104, 6, p. 571-581

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Bone Density
Antirheumatic Agents
Rheumatoid Arthritis
Healthy Volunteers
Tomography

Pulmonary CT registration through supervised learning with convolutional neural networks

Eppenhof, K. A. J. & Pluim, J. P. W., 2 May 2019, In : IEEE Transactions on Medical Imaging. 38, 5, p. 1097-1105 9 p., 8510836

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Supervised learning
Parameterization
Learning
Neural networks
Lung
3 Citations (Scopus)
Vascular Stiffness
Abdominal Aortic Aneurysm
Healthy Volunteers
Volunteers
Aortic Rupture

Quantifying guest–host dynamics in supramolecular assemblies to analyze their robustness

Bastings, M. M. C., Hermans, T. M., Spiering, A. J. H., Kemps, E. W. L., Albertazzi, L., Kurisinkal, E. E. & Dankers, P. Y. W., 1 Jan 2019, In : Macromolecular Bioscience. 19, 1, 11 p., 1800296

Research output: Contribution to journalArticleAcademicpeer-review

Pyrimidinones
Fluorescence Recovery After Photobleaching
Photobleaching
Fluorescence Resonance Energy Transfer
Microfluidics

Ratiometric bioluminescent sensor proteins based on intramolecular split luciferase complementation

Ni, Y., Arts, R. & Merkx, M., 25 Jan 2019, In : ACS Sensors. 4, 1, p. 20-25 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Luciferases
proteins
Proteins
sensors
Sensors

Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps

van Rijssel, M. J., Zijlstra, F., Seevinck, P. R., Luijten, P. R., Gilhuijs, K. G. A., Klomp, D. W. J. & Pluim, J. P. W., Jul 2019, In : Magnetic Resonance in Medicine. 82, 1, p. 425-435 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Echo-Planar Imaging
Breast
Nonparametric Statistics
Artifacts
Healthy Volunteers

RegressionExplorer: Interactive exploration of logistic regression models with subgroup analysis

Dingen, D., van 't Veer, M., Houthuizen, P., Mestrom, E. H. J., Korsten, E. H. H. M., Bouwman, A. R. A. & van Wijk, J., 1 Jan 2019, In : IEEE Transactions on Visualization and Computer Graphics. 25, 1, p. 246-255 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Logistics

Renal epithelial monolayer formation on monomeric and polymeric catechol functionalized supramolecular biomaterials

van Gaal, R. C., Fedecostante, M., Fransen, P. P. K. H., Masereeuw, R. & Dankers, P. Y. W., 2019, In : Macromolecular Bioscience. 19, 2, 7 p., 1800300

Research output: Contribution to journalArticleAcademicpeer-review

Pyrimidinones
Biocompatible Materials
Biomaterials
Catechols
Monolayers

Resorption of the calcium phosphate layer on S53P4 bioactive glass by osteoclasts

van Gestel, N., Schuiringa, R., Hennissen, J. H. P. H., Delsing, A., Ito, K., van Rietbergen, B., Hofmann, S. & Arts, C., 26 Jul 2019, (Accepted/In press) In : Journal of Materials Science: Materials in Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Bioactive glass
Calcium phosphate
Osteoclasts
Glass
Putty

Robust non-rigid motion compensation of free-breathing myocardial perfusion MRI data

Scannell, C. M., Villa, A. D. M., Lee, J., Breeuwer, M. & Chiribiri, A., 1 Aug 2019, In : IEEE Transactions on Medical Imaging. 38, 8, p. 1812-1820

Research output: Contribution to journalArticleAcademicpeer-review

Motion compensation
Magnetic Resonance Angiography
Magnetic resonance
Compensation and Redress
Respiration
3 Citations (Scopus)

Simultaneous micropatterning of fibrous meshes and bioinks for the fabrication of living tissue constructs

de Ruijter, M., Ribeiro, A., Dokter, I., Castilho, M. & Malda, J., 11 Apr 2019, In : Advanced Healthcare Materials. 8, 7, 7 p., 1800418

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Bioprinting
Tissue
Fabrication
Hydrogels
Fibers
2 Citations (Scopus)

Site-directed fragment-based screening for the discovery of protein-protein interaction stabilizers

Sijbesma, E., Hallenbeck, K. K., Leysen, S., de Vink, P. J., Skóra, L., Jahnke, W., Brunsveld, L., Arkin, M. R. & Ottmann, C., 27 Feb 2019, In : Journal of the American Chemical Society. 141, 8, p. 3524–3531 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Screening
Proteins
Estrogen Receptor alpha
Stabilization
Phosphorylation

Solvent impact assessment for the “One-Flow Functional Solvent Factory”

Morales-Gonzalez, O. M., Zhang, C., Li, S. & Hessel, V., 1 Aug 2019, In : Chemical Engineering Science: X. 3, 10 p., 100024

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Industrial plants
Ionic Liquids
Ionic liquids
Solubility
Acids

Spatial organization in proteinaceous membrane-stabilized coacervate protocells

Li, J., Liu, X., Abdelmohsen, L. K. E. A., Williams, D. S. & Huang, X., 12 Jul 2019, In : Small. 9 p., 1902893

Research output: Contribution to journalArticleAcademicpeer-review

Artificial Cells
Membranes
Buoyancy
Static Electricity
Self assembly

Super-resolution imaging of structure, molecular composition, and stability of single oligonucleotide polyplexes

Feiner-Gracia, N., Olea, R. A., Fitzner, R., El Boujnouni, N., van Asbeck, A. H., Brock, R. & Albertazzi, L., 8 May 2019, In : Nano Letters. 19, 5, p. 2784-2792 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
oligonucleotides
Oligonucleotides
Cell-Penetrating Peptides
Molecular structure
Peptides

Super-resolution microscopy on single particles at fluid interfaces reveals their wetting properties and interfacial deformations

Aloi, A., Vilanova, N., Isa, L., de Jong, A. M. & Voets, I. K., 14 Apr 2019, In : Nanoscale. 11, 14, p. 6654-6661 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Wetting
Microscopic examination
Contact angle
Fluids
Colloids

Super-resolution microscopy reveals significant impact of M2e-specific monoclonal antibodies on influenza A virus filament formation at the host cell surface

Kolpe, A., Arista-Romero, M., Schepens, B., Pujals, S., Saelens, X. & Albertazzi, L., 14 Mar 2019, In : Scientific Reports. 9, 1, 14 p., 4450

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Influenza A virus
Microscopy
Monoclonal Antibodies
Virus Replication
Viruses
1 Citation (Scopus)
antifouling
Scaffolds
Adhesives
adhesives
casts

Supramolecular modification of a sequence-controlled collagen-mimicking polymer

Spaans, S., Fransen, P. P. K. H., Schotman, M. J. G., van der Wulp, R., Lafleur, R. P. M., Kluijtmans, S. G. J. M. & Dankers, P. Y. W., 10 Jun 2019, In : Biomacromolecules. 20, 6, p. 2360-2371 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pyrimidinones
Collagen
Hydrogels
Polymers
Recombinant proteins
1 Citation (Scopus)

Tetrazine - trans-cyclooctene chemistry applied to fabricate self-assembled fluorescent and radioactive nanoparticles for in vivo dual mode imaging

van Onzen, A. H. A. M., Rossin, R., Schenning, A. P. H. J., Nicolay, K., Milroy, L. G., Robillard, M. S. & Brunsveld, L., 1 Jan 2019, In : Bioconjugate Chemistry. 30, 3, p. 547–551 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoparticles
Imaging techniques
Molecules
Multimodal Imaging
Radioactivity

The association between prevalent vertebral fractures and bone quality of the distal radius and distal tibia as measured with HR-pQCT in postmenopausal women with a recent non-vertebral fracture at the Fracture Liaison Service

Vranken, L., Wyers, C. E., van Rietbergen, B., Driessen, J. H. M., Geusens, P. P. M. M., Janzing, H. M. J., van der Velde, R. Y. & van den Bergh, J. P. W., 17 Jul 2019, In : Osteoporosis International.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Bone Fractures
Tibia
Bone and Bones
Stress Fractures
Compressive Strength
1 Citation (Scopus)

The dual-mode dipole: A new array element for 7T body imaging with reduced SAR

Solomakha, G., Leeuwen, C. V., Raaijmakers, A., Simovski, C., Popugaev, A., Abdeddaim, R., Melchakova, I. & Glybovski, S., 1 Feb 2019, In : Magnetic Resonance in Medicine. 81, 2, p. 1459-1469

Research output: Contribution to journalArticleAcademicpeer-review

Prostate
Volunteers
1 Citation (Scopus)

The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies

European Eye Epidemiology Consortium, Gattoussi, S. & Berendschot, T., 1 Jun 2019, In : Acta Ophthalmologica. 97, 4, p. 364-371 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

The influence of model order reduction on the computed fractional flow reserve using parameterized coronary geometries

Gashi, K., Bosboom, E. M. H. & van de Vosse, F. N., 3 Jan 2019, In : Journal of Biomechanics. 82, p. 313-323

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pathologic Constriction
Geometry
Hydrodynamics
Uncertainty
Dynamic models

Therapeutic drug monitoring van adalimumab bij patiënten met inflammatoire darmziekten

van 't Geloof, W., Boekema, P. J., Gilissen, L. P. L., Broeren, M. A. C. & Derijks, L. J. J., 15 Mar 2019, In : Pharmaceutisch Weekblad. 154, 11, p. 29-32 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Drug Monitoring
Inflammatory Bowel Diseases
Adalimumab
Outpatients
Quality of Life

Therapeutic drug monitoring van adalimumab bij reumatologische patiënten

Kylstra, A. H., Benoy-de Keuster, S., Traksel, R. A. M., Broeren, M. A. C. & Derijks, L. J. J., 8 Feb 2019, In : Pharmaceutisch Weekblad. 154, 6, p. 25-28 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Drug Monitoring
Adalimumab
Hospital Information Systems
Psoriatic Arthritis
Ankylosing Spondylitis
Pressure Ulcer
Wounds and Injuries
Edema
Muscles

Traction forces at the cytokinetic ring regulate cell division and polyploidy in the migrating zebrafish epicardium

Uroz, M., Garcia-Puig, A., Tekeli, I., Elosegui-Artola, A., Abenza, J. F., Marín-Llauradó, A., Pujals, S., Conte, V., Albertazzi, L., Roca-Cusachs, P., Raya, Á. & Trepat, X., 3 Jun 2019, (Accepted/In press) In : Nature Materials.

Research output: Contribution to journalArticleAcademicpeer-review

epicardium
cell division
traction
Cells
adhesion

Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation

Egli-Spichtig, D., Imenez Silva, P. H., Glaudemans, B., Gehring, N., Bettoni, C., Zhang, M. Y. H., Pastor-Arroyo, E. M., Schönenberger, D., Rajski, M., Hoogewijs, D., Knauf, F., Misselwitz, B., Frey-Wagner, I., Rogler, G., Ackermann, D., Ponte, B., Pruijm, M., Leichtle, A., Fiedler, G-M., Bochud, M. & 8 othersBallotta, V., Hofmann, S., Perwad, F., Föller, M., Lang, F., Wenger, R. H., Frew, I. & Wagner, C. A., 14 May 2019, In : Kidney International.

Research output: Contribution to journalArticleAcademicpeer-review

Chronic Renal Insufficiency
Tumor Necrosis Factor-alpha
Inflammation
Kidney
fibroblast growth factor 23

Unexpectedly strong chiral amplification of chiral/achiral and chiral/chiral copolymers of biphenylylacetylenes and further enhancement/inversion and memory of the macromolecular helicity

Ishidate, R., Markvoort, B., Maeda, K. & Yashima, E., 22 Apr 2019, In : Journal of the American Chemical Society. 141, 18, p. 7605-7614

Research output: Contribution to journalArticleAcademicpeer-review

Circular Dichroism
Amplification
Polymers
Copolymers
Alcohols

Validation of distal radius failure load predictions by homogenized- and micro-finite element analyses based on second-generation high-resolution peripheral quantitative CT images

Arias Moreno, A. J., Hosseini, H., Bevers, M. S. A. M., Ito, K., Zysset, P. K. & van Rietbergen, B., 17 Apr 2019, In : Osteoporosis International.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Finite Element Analysis
Cadaver
Equipment and Supplies
Clinical Studies

What is the potential of tissue-engineered pulmonary valves in children?

Huygens, S. A., Rutten-van Mölken, M. P. M. H., Noruzi, A., Etnel, J. R. G., Corro Ramos, I., Bouten, C. V. C., Kluin, J. & Takkenberg, J. J. M., Jun 2019, In : The Annals of Thoracic Surgery. 107, 6, p. 1845-1853

Research output: Contribution to journalArticleAcademicpeer-review

Pulmonary Valve
Heart Valves
Costs and Cost Analysis
Quality-Adjusted Life Years
Patient Simulation
2018
9 Citations (Scopus)
Open Access
File
Biomimetics
Microfluidics
Endothelial cells
Hemodynamics
Vascular Smooth Muscle
4 Citations (Scopus)

Accelerated 4D phase contrast MRI in skeletal muscle contraction

Mazzoli, V., Gottwald, L. M., Peper, E. S., Froeling, M., Coolen, B. F., Verdonschot, N., Sprengers, A. M., van Ooij, P., Strijkers, G. J. & Nederveen, A. J., 1 Nov 2018, In : Magnetic Resonance in Medicine. 80, 5, p. 1799-1811 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Muscle Contraction
Skeletal Muscle
Muscles
Volunteers
Leg
6 Citations (Scopus)

Accelerating DNA-based computing on a supramolecular polymer

Engelen, W., Wijnands, S. P. W. & Merkx, M., 1 Aug 2018, In : Journal of the American Chemical Society. 140, 30, p. 9758-9767 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polymers
DNA
Benzene
Networks (circuits)
Molecular Computers
5 Citations (Scopus)

Adaptation of a MR imaging protocol into a real-time clinical biometric ultrasound protocol for persons with spinal cord injury at risk for deep tissue injury: A reliability study

Swaine, J. M., Moe, A., Breidahl, W., Bader, D. L., Oomens, C. W. J., Lester, L., O'Loughlin, E., Santamaria, N. & Stacey, M. C., 1 Feb 2018, In : Journal of Tissue Viability. 27, 1, p. 2-9 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Spinal Cord Injuries
Tendons
Skin
Spinal Cord
Wounds and Injuries

Adaptive polymersome and micelle morphologies in anticancer nanomedicine: from design rationale to fabrication and proof-of-concept studies

Pijpers, I. A. B., Abdelmohsen, L. K. E. A., Xia, Y., Cao, S., Williams, D. S., Meng, F., van Hest, J. C. M. & Zhong, Z., 1 Dec 2018, In : Advanced Therapeutics. 1, 8, 14 p., 1800068

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Medical nanotechnology
Micelles
Nanoparticles
Fabrication
Drug delivery

A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

De Jong, E., Williams, D. S., Abdelmohsen, L. K. E. A., van Hest, J. C. M. & Zuhorn, I. S., 10 Nov 2018, In : Journal of Controlled Release. 289, p. 14-22 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Fluorescence Spectrometry
Blood-Brain Barrier
Nanoparticles
Transcytosis
Brain
6 Citations (Scopus)

AFM-detected apoptosis of hepatocellular carcinoma cells induced by American ginseng root water extract

Qu, Y., Wang, Z., Zhao, F., Liu, J., Zhang, W., Li, J., Song, Z. & Xu, H., 1 Jan 2018, In : Micron. 104, p. 1-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Panax
Hepatocellular Carcinoma
Apoptosis
Water
Elastic Modulus
Open Access
Biomarkers
Blood Vessels
Retina
Retinal Vessels
Pipelines
2 Citations (Scopus)

A liquid chromatography/mass spectrometry method for screening disulfide tethering fragments

Hallenbeck, K. K., Davies, J. L., Merron, C., Ogden, P., Sijbesma, E., Ottmann, C., Renslo, A. R., Wilson, C. & Arkin, M. R., 2018, In : SLAS Discovery. 23, 2, p. 183-192 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Liquid chromatography
Disulfides
Mass spectrometry
Screening
Pipelines