Department of Biomedical Engineering

Research Output 1962 2019

Filter
Article
2019

A comparative study of geometry-based methods and intra-arterial pressure measurements to assess the hemodynamic significance of equivocal iliac artery stenoses

Heinen, S. G. H., Huberts, W., van den Heuvel, D. A. F., van de Vosse, F. N., de Vries, J. P. P. M. & Delhaas, T., 1 Apr 2019, In : Vascular. 27, 2, p. 119-127 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Arterial Pressure
Pathologic Constriction
Hemodynamics
Blood Vessels

A computational model to predict cell traction-mediated prestretch in the mitral valve

van Kelle, M. A. J., Rausch, M. K., Kuhl, E. & Loerakker, S., 19 Aug 2019, In : Computer Methods in Biomechanics and Biomedical Engineering.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Tissue
Actins
Structural properties
Anisotropy
Fibers

Adaptive polymersome nanoreactors

Che, H. & van Hest, J. C. M., 1 Sep 2019, In : ChemNanoMat. 5, 9, p. 1092-1109

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoreactors
Medical nanotechnology
Adaptive systems

Adherence to dabigatran etexilate in atrial fibrillation patients intended to undergo electrical cardioversion

Comuth, W. J., de Maat, M. P. M., van de Kerkhof, D., Malczynski, J., Husted, S., Kristensen, S. D. & Münster, A. M. B., 1 Apr 2019, In : European Heart Journal - Cardiovascular Pharmacotherapy. 5, 2, p. 91-99 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Electric Countershock
Atrial Fibrillation
Medication Adherence
Therapeutics
Dabigatran

A geometry-based model for non-invasive estimation of pressure gradients over iliac artery stenoses

Heinen, S. G. H., van den Heuvel, D. A. F., de Vries, J. P. P. M., van de Vosse, F. N., Delhaas, T. & Huberts, W., 19 Jul 2019, In : Journal of Biomechanics. 92, p. 67-75

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Pressure gradient
Pathologic Constriction
Angiography
Pressure

Alendronate-functionalized poly(2-oxazoline)s with tunable affinity for calcium cations

Sánchez-Fernández, M. J., Immers, M. R., Félix Lanao, R. P., Yang, F., Bender, J. C. M. E., Mecinović, J., Leeuwenburgh, S. C. G. & van Hest, J. C. M., 1 Jan 2019, In : Biomacromolecules. 20, 8, p. 2913-2921 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Alendronate
Cations
Calcium
Polymers
Positive ions
3 Citations (Scopus)

Allosteric small molecule modulators of nuclear receptors

Meijer, F. A., Leijten-van de Gevel, I. A., de Vries, R. M. J. M. & Brunsveld, L., 1 Apr 2019, In : Molecular and Cellular Endocrinology. 485, p. 20-34 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cytoplasmic and Nuclear Receptors
Allosteric Site
Ligands
Drug Discovery
Pathology
Open Access
File
Intravenous Administration
Theoretical Models
Clinical Decision Support Systems
Mathematical models
Fluids

AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins

Saline, M., Badertscher, L., Wolter, M., Lau, R., Gunnarsson, A., Jacso, T., Norris, T., Ottmann, C. & Snijder, A., 1 Jan 2019, In : Journal of Biological Chemistry. 294, 35, p. 13106-13116 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

14-3-3 Proteins
Phosphorylation
AMP-Activated Protein Kinases
Protein Kinases
Transcription Factors

A multicenter evaluation of a point of care CRP Test

Scharnhorst, V., Noordzij, P. G., Lutz, A., Graser, U., Püntener, D. & Alquézar-Arbé, A., 1 Sep 2019, In : Clinical Biochemistry. 71, Sept 2019, p. 38-45

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Point-of-Care Systems
C-Reactive Protein
Blood
Serum
Plasmas

A multilayer microfluidic platform for the conduction of prolonged cell-free gene expression

van der Linden, A., Pieters, P., Yelleswarapu, M., Swank, Z., Huck, W. T. S., Maerkl, S. & de Greef, T., 2019, (Accepted/In press) In : Journal of Visualized Experiments (JoVE).

Research output: Contribution to journalArticleAcademicpeer-review

File
Lab-On-A-Chip Devices
Microfluidics
Transcription
Gene expression
Multilayers
Open Access
Tissue Scaffolds
Tissue Engineering
Scaffold
Microfluidics
Fluidics

Analysis of chemical exchange saturation transfer contributions from brain metabolites to the Z-spectra at various field strengths and pH

Khlebnikov, V., van der Kemp, W. J. M., Hoogduin, H., Klomp, D. W. J. & Prompers, J. J., 31 Jan 2019, In : Scientific Reports. 9, 11 p., 1089

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

An aptamer-based new method for competitive fluorescence detection of exosomes

Yu, X., He, L., Pentok, M., Yang, H., Yang, Y., Li, Z., He, N., Deng, Y., Li, S., Liu, T., Chen, X. & Luo, H., 7 Sep 2019, In : Nanoscale. 11, 33, p. 15589-15595 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fluorescence
Biomarkers
Costs
Cells
Proteins

A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitude

Gigante, A., Grad, J. N., Briels, J., Bartel, M., Hoffmann, D., Ottmann, C. & Schmuck, C., 1 Jan 2019, In : Chemical Communications. 55, 1, p. 111-114 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Neurodegenerative diseases
14-3-3 Proteins
Signal transduction
Ligands
Proteins

An iterative sparse deconvolution method for simultaneous multicolor 19F-MRI of multiple contrast agents

Schoormans, J., Calcagno, C., Daal, M. R. R., Wüst, R. C. I., Faries, C., Maier, A., Teunissen, A. J. P., Naidu, S., Sanchez-Gaytan, B. L., Nederveen, A. J., Fayad, Z. A., Mulder, W. J. M., Coolen, B. F. & Strijkers, G. J., 10 Jul 2019, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Contrast Media
Artifacts
Fluorine
Noise
Cell Tracking
1 Citation (Scopus)

A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: Towards in situ tissue-engineered vascular accesses for haemodialysis

van Uden, S., Vanerio, N., Catto, V., Bonandrini, B., Tironi, M., Figliuzzi, M., Remuzzi, A., Kock, L., Redaelli, A. C. L., Greco, F. G. & Riboldi, S. A., 1 Mar 2019, In : Biomedical Materials. 14, 2, p. 025007 18 p., 025007

Research output: Contribution to journalArticleAcademicpeer-review

Fibroins
Polyurethanes
Silk
Grafts
Tissue

A pipette-tip based method for seeding cells to droplet microfluidic platforms

Sinha, N., Subedi, N., Wimmers, F., Soennichsen, M. & Tel, J., 11 Feb 2019, In : Journal of visualized experiments : JoVE. 144, 10 p., e57848

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cloud seeding
Microfluidics
Encapsulation
Poisson distribution
Poisson Distribution
Hypothermia
Myocardial Infarction
Temperature
Myocardial Reperfusion
Myocardium

A protocol update of the fractional flow reserve versus angiography for multivessel evaluation (FAME) 3 trial: a comparison of fractional flow reserve–guided percutaneous coronary intervention and coronary artery bypass graft surgery in patients with multivessel coronary artery disease

Zimmermann, F. M., de Bruyne, B., Pijls, N. H. J., Desai, M., Oldroyd, K. G., Reardon, M. J., Wendler, O., Woo, J., Yeung, A. C. & Fearon, W. F., 1 Aug 2019, In : American Heart Journal. 214, p. 156-157 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

A revised modular approach to (–)-trans-Δ 8 -THC and derivatives through late-stage Suzuki–Miyaura cross-coupling reactions

Bloemendal, V. R. L. J., Sondag, D., Elferink, H., Boltje, T. J., van Hest, J. C. M. & Rutjes, F. P. J. T., 31 Mar 2019, In : European Journal of Organic Chemistry. 2019, 12, p. 2289-2296 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
thermohaline circulation
Dronabinol
cross coupling
Derivatives
Scaffolds

Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins

Maity, D., Gigante, A., Sánchez-Murcia, P. A., Sijbesma, E., Li, M., Bier, D., Mosel, S., Knauer, S., Ottmann, C. & Schmuck, C., 2 Apr 2019, In : Organic and Biomolecular Chemistry. 17, 17, p. 4359-4363 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

14-3-3 Proteins
peptides
Arginine
Fluorescence
proteins

Association of improvement in fractional flow reserve with outcomes, including symptomatic relief, after percutaneous coronary intervention

Fournier, S., Ciccarelli, G., Toth, G. G., Milkas, A., Xaplanteris, P., Tonino, P. A. L., Fearon, W. F., Pijls, N. H. J., Barbato, E. & de Bruyne, B., 1 Apr 2019, In : JAMA Cardiology. 4, 4, p. 370-374 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Percutaneous Coronary Intervention
Angiography
Coronary Artery Disease
Randomized Controlled Trials
North America

A stirring system using suspended magnetically-actuated pillars for controlled cell clustering

Saberi, A., Zhang, S., van den Bersselaar, C., Kandail, H., den Toonder, J. M. J. & Kurniawan, N. A., 1 Jan 2019, In : Soft Matter. 15, 6, p. 1435-1443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

stirring
Magnetic scales
Colloids
Research laboratories
cells
1 Citation (Scopus)

A stochastic view on surface inhomogeneity of nanoparticles

Post, R. A. J., van der Zwaag, D., Bet, G., Wijnands, S. P. W., Albertazzi, L., Meijer, E. W. & van der Hofstad, R. W., 10 Apr 2019, In : Nature Communications. 10, 1, 11 p., 1663

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoparticles
inhomogeneity
nanoparticles
Microscopy
Microscopic examination
Open Access
File
Biocompatible Materials
Pyrimidinones
Proteins
Notch1 Receptor
Click Chemistry

A survey of crowdsourcing in medical image analysis

Ørting, S., Doyle, A., Hirth, M., van Hilten, A., Inel, O., Madan, C. R., Mavridis, P., Spiers, H. & Cheplygina, V., 25 Feb 2019, In : arXiv. 12 p., 1902.09159

Research output: Contribution to journalArticleAcademic

Open Access
File
Image analysis
Astrophysics
Medical imaging
Metadata
Learning algorithms

Atherosclerotic carotid bifurcation phantoms with stenotic soft inclusions for ultrasound flow and vessel wall elastography imaging

Chayer, B., van den Hoven, M., Roy Cardinal, M. H., Li, H., Swillens, A., Lopata, R. & Cloutier, G., 2 May 2019, In : Physics in Medicine and Biology. 64, 9, 12 p., 095025

Research output: Contribution to journalArticleAcademicpeer-review

Elasticity Imaging Techniques
Blood Vessels
Elastic Modulus
Internal Carotid Artery
Atherosclerotic Plaques
Nanosystems
Adenosine Triphosphate
Polylysine
Nanoreactors
Molecular interactions

Automatic classification of focal liver lesions based on MRI and risk factors

Jansen, M. J. A., Kuijf, H. J., Veldhuis, W. B., Wessels, F. J., Viergever, M. A. & Pluim, J. P. W., 2019, In : PLoS ONE. 14, 5, 13 p., e0217053

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
lesions (animal)
Liver
Magnetic resonance imaging
risk factors
liver

A value proposition for through level-based anti-TNFα drug dosing

Scharnhorst, V., Schmitz, E. M. H., van de Kerkhof, D., Derijks, L. J. J. & Broeren, M. A. C., 1 Feb 2019, In : Clinica Chimica Acta. 489, p. 89-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Monitoring
Pharmaceutical Preparations
Cost-Benefit Analysis
Therapeutics
Critical Pathways

A versatile protocol for studying anterior cruciate ligament reconstruction in a rabbit model

Hevesi, M., Crispim, J. F., Paggi, C. A., Dudakovic, A., van Genechten, W., Hewett, T., Kakar, S., Krych, A. J., van Wijnen, A. J. & Saris, D., 19 Mar 2019, In : Tissue Engineering. Part C: Methods. 25, 4, p. 191-196 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Anterior Cruciate Ligament Reconstruction
Ligaments
Anterior Cruciate Ligament
Rabbits
Animal Care Committees

Benchmark on automatic 6-month-old infant brain segmentation algorithms: The iSeg-2017 Challenge

Wang, L., Nie, D., Li, G., Puybareau, E., Dolz, J., Zhang, Q., Wang, F., Xia, J., Wu, Z., Chen, J., Thung, K-H., Bui, T. D., Shin, J., Zeng, G., Zheng, G., Fonov, V. S., Doyle, A., Xu, Y., Moeskops, P., Pluim, J. P. W. & 9 othersDesrosiers, C., Ayed, I. B., Sanroma, G., Benkarim, O. M., Casamitjana, A., Vilaplana, V., Lin, W., Li, G. & Shen, D., 27 Feb 2019, In : IEEE Transactions on Medical Imaging. 38, 9, p. 2219-2230

Research output: Contribution to journalArticleAcademicpeer-review

Benchmarking
Brain
Magnetic resonance
Magnetic Resonance Spectroscopy
Cerebrospinal fluid
1 Citation (Scopus)

Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration

Castilho, M., Mouser, V., Chen, M., Malda, J. & Ito, K., 1 Sep 2019, In : Acta Biomaterialia. 95, Sept 2019, p. 297-306

Research output: Contribution to journalArticleAcademicpeer-review

Hydrogels
Cartilage
Articular Cartilage
Regeneration
Fibers

Biomedical applications of photo- and sono-activated Rose Bengal: a review

Vanerio, N., Stijnen, M., de Mol, B. A. J. M. & Kock, L. M., 1 Jul 2019, In : Photobiomodulation, Photomedicine, and Laser Surgery. 37, 7, p. 383-394 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Rose Bengal
Oncology
Xanthenes
Photodynamic therapy
Oxygen
2 Citations (Scopus)

Biomorphic engineering of multifunctional polylactide stomatocytes toward therapeutic nano-red blood cells

Shao, J., Pijpers, I. A. B., Cao, S., Williams, D. S., Yan, X., Li, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 1 Jan 2019, In : Advanced Science. 6, 5, 8 p., 1801678

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
erythrocytes
Blood
Erythrocytes
Cells
engineering

Bone microarchitecture and distal radius fracture pattern complexity

Daniels, A. M., Theelen, L. M. A., Wyers, C. E., Janzing, H. M. J., van Rietbergen, B., Vranken, L., van der Velde, R. Y., Geusens, P. P. M. M., Kaarsemaker, S., Poeze, M. & van den Bergh, J. P., 10 Jul 2019, In : Journal of Orthopaedic Research. 37, 8, p. 1690-1697

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Radius Fractures
Bone Density
Bone and Bones
Joints
Odds Ratio
6 Citations (Scopus)

Carbon nanotube reinforced supramolecular hydrogels for bioapplications

Mihajlovic, M., Mihajlovic, M., Dankers, P. Y. W., Masereeuw, R. & Sijbesma, R. P., 1 Jan 2019, In : Macromolecular Bioscience. 19, 12 p., 1800173

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Carbon Nanotubes
Hydrogels
Nanocomposites
Carbon nanotubes
Hydrogel

Cardiomyocyte contractile force changes in response to AGRWE detected by AFM

Qu, Y. M., Zhao, F., Wang, X., Liu, J., Li, J., Song, Z. & Wang, Z., 2 May 2019, In : Micro and Nano Letters. 14, 5, p. 511-514 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

atomic force microscopy
Water
water
synchronism
heart rate

Cats or CAT scans: transfer learning from natural or medical image source data sets?

Cheplygina, V., Mar 2019, In : Current Opinion in Biomedical Engineering. 9, p. 21-27

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
learning
tomography
image analysis
train

Cell-perceived substrate curvature dynamically coordinates the direction, speed, and persistence of stromal cell migration

Werner, M., Petersen, A., Kurniawan, N. & Bouten, C., 5 Sep 2019, In : Advanced Biosystems. 2019, 11 p., 1900080

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Stromal Cells
Cell Movement
Bone
Biocompatible Materials
Substrates

Characteristics of surgical prosthetic heart valves and problems around labelling: a document from the European Association for Cardio-Thoracic Surgery (EACTS)-the society of thoracic surgeons (STS)-american association for thoracic surgery (AATS) valve labelling task force

Durko, A. P., Head, S. J., Pibarot, P., Atluri, P., Bapat, V., Cameron, D. E., Casselman, F. P. A., Chen, E. P., Dahle, G., Ebels, T., Elefteriades, J. A., Lancellotti, P., Prager, R. L., Rosenhek, R., Speir, A., Stijnen, M., Tasca, G., Yoganathan, A., Walther, T. & de Paulis, R., 1 Jun 2019, In : European Journal of Cardio-Thoracic Surgery. 55, 6, p. 1025-1036 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Heart Valves
Advisory Committees
Thoracic Surgery
Thorax
Organizations
Heart Valves
Advisory Committees
Thoracic Surgery
Thorax
Organizations

Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples

Félix Garza, Z. C., Lenz, M., Liebmann, J., Ertaylan, G., Born, M., Arts, I. C. W., Hilbers, P. A. J. & Van Riel, N. A. W., 17 Aug 2019, In : BMC Medical Genomics. 12, 1, 14 p., 121

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Biopsy
Skin
Atopic Dermatitis
Psoriasis
Skin Diseases
2 Citations (Scopus)

CHD1 loss alters AR binding at lineage-specific enhancers and modulates distinct transcriptional programs to drive prostate tumorigenesis

Augello, M. A., Liu, D., Deonarine, L. D., Robinson, B. D., Huang, D., Stelloo, S., Blattner, M., Doane, A. S., Wong, E. W. P., Chen, Y., Rubin, M. A., Beltran, H., Elemento, O., Bergman, A. M., Zwart, W., Sboner, A., Dephoure, N. & Barbieri, C. E., 15 Apr 2019, In : Cancer Cell. 35, 4, p. 603-617

Research output: Contribution to journalArticleAcademicpeer-review

Androgen Receptors
Prostate
Carcinogenesis
Neoplasms
Prostatic Neoplasms

Chemoenzymatic synthesis of sialic acid derivatives using immobilized N-acetylneuraminate lyase in a continuous flow reactor

Bloemendal, V. R. L. J., Moons, S. J., Heming, J. J. A., Chayoua, M., Niesink, O., van Hest, J. C. M., Boltje, T. J. & Rutjes, F. P. J. T., 8 May 2019, In : Advanced Synthesis & Catalysis. 361, 11, p. 2443-2447

Research output: Contribution to journalArticleAcademicpeer-review

N-acetylneuraminate lyase
N-Acetylneuraminic Acid
Derivatives
Acids
Sialic Acids

Clinical interpretation of prostate-specific antigen values: type of applied cut-off value exceeds methods bias as the major source of variation

Klinkenberg, L. J. J., Lentjes, E. G. W. M. & Boer, A. K., 1 Mar 2019, In : Annals of Clinical Biochemistry. 56, 2, p. 259-265 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prostate-Specific Antigen
Prostatic Neoplasms
Biopsy
Linear regression
Standardization

Combined enzymatic degradation of proteoglycans and collagen significantly alters intratissue strains in articular cartilage during cyclic compression

Pastrama, M. I., Ortiz, A. C., Zevenbergen, L., Famaey, N., Gsell, W., Neu, C. P., Himmelreich, U. & Jonkers, I., 1 Oct 2019, In : Journal of the Mechanical Behavior of Biomedical Materials. 98, p. 383-394 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cartilage
Proteoglycans
Collagen
Degradation
Enzymes

Comparing signal-to-noise ratio for prostate imaging at 7T and 3T

Steensma, B. R., Luttje, M., Voogt, I. J., Klomp, D. W. J., Luijten, P. R., van den Berg, C. A. T. & Raaijmakers, A. J. E., May 2019, In : Journal of Magnetic Resonance Imaging. 49, 5, p. 1446-1455

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Signal-To-Noise Ratio
Prostate
Volunteers
Neoplasms
Protons

Computational modelling of energy balance in individuals with Metabolic Syndrome

Rozendaal, Y., Wang, Y., Hilbers, P. & van Riel, N., 26 Feb 2019, In : BMC Systems Biology. 13, 24, 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Computational Modeling
Energy Balance
Energy balance
Energy Metabolism
Energy