Department of Biomedical Engineering

Research Output 1962 2019

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Article
2019

Adaptive polymersome nanoreactors

Che, H. & van Hest, J. C. M., 27 May 2019, In : ChemNanoMat.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nanoreactors
Medical nanotechnology
Adaptive systems

Adherence to dabigatran etexilate in atrial fibrillation patients intended to undergo electrical cardioversion

Comuth, W. J., de Maat, M. P. M., van de Kerkhof, D., Malczynski, J., Husted, S., Kristensen, S. D. & Münster, A. M. B., 1 Apr 2019, In : European Heart Journal - Cardiovascular Pharmacotherapy. 5, 2, p. 91-99 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Electric Countershock
Atrial Fibrillation
Medication Adherence
Therapeutics
Dabigatran

A geometry-based model for non-invasive estimation of pressure gradients over iliac artery stenoses

Heinen, S. G. H., van den Heuvel, D. A. F., de Vries, J. P. P. M., van de Vosse, F. N., Delhaas, T. & Huberts, W., 24 May 2019, In : Journal of Biomechanics. 92, p. 67-75

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Pressure gradient
Pathologic Constriction
Angiography
Pressure
2 Citations (Scopus)

Allosteric small molecule modulators of nuclear receptors

Meijer, F. A., Leijten-van de Gevel, I. A., de Vries, R. M. J. M. & Brunsveld, L., 1 Apr 2019, In : Molecular and Cellular Endocrinology. 485, p. 20-34 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cytoplasmic and Nuclear Receptors
Allosteric Site
Ligands
Drug Discovery
Pathology
Open Access
File
Intravenous Administration
Theoretical Models
Clinical Decision Support Systems
Mathematical models
Fluids

A multilayer microfluidic platform for the conduction of prolonged cell-free gene expression

van der Linden, A., Pieters, P., Yelleswarapu, M., Swank, Z., Huck, W. T. S., Maerkl, S. & de Greef, T., 2019, (Accepted/In press) In : Journal of Visualized Experiments (JoVE).

Research output: Contribution to journalArticleAcademicpeer-review

File
Lab-On-A-Chip Devices
Microfluidics
Transcription
Gene expression
Multilayers
Open Access
Tissue Scaffolds
Tissue Engineering
Scaffold
Microfluidics
Fluidics

A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitude

Gigante, A., Grad, J. N., Briels, J., Bartel, M., Hoffmann, D., Ottmann, C. & Schmuck, C., 1 Jan 2019, In : Chemical Communications. 55, 1, p. 111-114 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Neurodegenerative diseases
14-3-3 Proteins
Signal transduction
Ligands
Proteins

A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: Towards in situ tissue-engineered vascular accesses for haemodialysis

van Uden, S., Vanerio, N., Catto, V., Bonandrini, B., Tironi, M., Figliuzzi, M., Remuzzi, A., Kock, L., Redaelli, A. C. L., Greco, F. G. & Riboldi, S. A., 1 Mar 2019, In : Biomedical Materials. 14, 2, p. 025007 18 p., 025007

Research output: Contribution to journalArticleAcademicpeer-review

Fibroins
Polyurethanes
Silk
Grafts
Tissue

A pipette-tip based method for seeding cells to droplet microfluidic platforms

Sinha, N., Subedi, N., Wimmers, F., Soennichsen, M. & Tel, J., 11 Feb 2019, In : Journal of visualized experiments : JoVE. 144, 10 p., e57848

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cloud seeding
Microfluidics
Encapsulation
Poisson distribution
Poisson Distribution
Hypothermia
Myocardial Infarction
Temperature
Myocardial Reperfusion
Myocardium

A protocol update of the fractional flow reserve versus angiography for multivessel evaluation (FAME) 3 trial: a comparison of fractional flow reserve–guided percutaneous coronary intervention and coronary artery bypass graft surgery in patients with multivessel coronary artery disease

Zimmermann, F. M., de Bruyne, B., Pijls, N. H. J., Desai, M., Oldroyd, K. G., Reardon, M. J., Wendler, O., Woo, J., Yeung, A. C. & Fearon, W. F., 1 Aug 2019, In : American Heart Journal. 214, p. 156-157 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

A revised modular approach to (–)-trans-Δ 8 -THC and derivatives through late-stage Suzuki–Miyaura cross-coupling reactions

Bloemendal, V. R. L. J., Sondag, D., Elferink, H., Boltje, T. J., van Hest, J. C. M. & Rutjes, F. P. J. T., 31 Mar 2019, In : European Journal of Organic Chemistry. 2019, 12, p. 2289-2296 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
thermohaline circulation
Dronabinol
cross coupling
Derivatives
Scaffolds

Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins

Maity, D., Gigante, A., Sánchez-Murcia, P. A., Sijbesma, E., Li, M., Bier, D., Mosel, S., Knauer, S., Ottmann, C. & Schmuck, C., 2 Apr 2019, In : Organic and Biomolecular Chemistry. 17, 17, p. 4359-4363 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

14-3-3 Proteins
peptides
Arginine
Fluorescence
proteins

Association of improvement in fractional flow reserve with outcomes, including symptomatic relief, after percutaneous coronary intervention

Fournier, S., Ciccarelli, G., Toth, G. G., Milkas, A., Xaplanteris, P., Tonino, P. A. L., Fearon, W. F., Pijls, N. H. J., Barbato, E. & de Bruyne, B., 1 Apr 2019, In : JAMA Cardiology. 4, 4, p. 370-374 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Percutaneous Coronary Intervention
Angiography
Coronary Artery Disease
Randomized Controlled Trials
North America

A stirring system using suspended magnetically-actuated pillars for controlled cell clustering

Saberi, A., Zhang, S., van den Bersselaar, C., Kandail, H., den Toonder, J. M. J. & Kurniawan, N. A., 1 Jan 2019, In : Soft Matter. 15, 6, p. 1435-1443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

stirring
Magnetic scales
Colloids
Research laboratories
cells

A stochastic view on surface inhomogeneity of nanoparticles

Post, R. A. J., van der Zwaag, D., Bet, G., Wijnands, S. P. W., Albertazzi, L., Meijer, E. W. & van der Hofstad, R. W., 10 Apr 2019, In : Nature Communications. 10, 1, 11 p., 1663

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoparticles
inhomogeneity
nanoparticles
Microscopy
Microscopic examination

A survey of crowdsourcing in medical image analysis

Ørting, S., Doyle, A., Hirth, M., van Hilten, A., Inel, O., Madan, C. R., Mavridis, P., Spiers, H. & Cheplygina, V., 25 Feb 2019, In : arXiv. 12 p., 1902.09159

Research output: Contribution to journalArticleAcademic

Open Access
File
Image analysis
Astrophysics
Medical imaging
Metadata
Learning algorithms

Atherosclerotic carotid bifurcation phantoms with stenotic soft inclusions for ultrasound flow and vessel wall elastography imaging

Chayer, B., van den Hoven, M., Roy Cardinal, M. H., Li, H., Swillens, A., Lopata, R. & Cloutier, G., 2 May 2019, In : Physics in Medicine and Biology. 64, 9, 12 p., 095025

Research output: Contribution to journalArticleAcademicpeer-review

Elasticity Imaging Techniques
Blood Vessels
Elastic Modulus
Internal Carotid Artery
Atherosclerotic Plaques

A value proposition for trough level-based anti-TNFα drug dosing

Scharnhorst, V., Schmitz, E. M. H., van de Kerkhof, D., Derijks, L. J. J. & Broeren, M. A. C., 1 Feb 2019, In : Clinica Chimica Acta. 489, p. 89-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Monitoring
Pharmaceutical Preparations
Cost-Benefit Analysis
Therapeutics
Critical Pathways

A versatile protocol for studying anterior cruciate ligament reconstruction in a rabbit model

Hevesi, M., Crispim, J. F., Paggi, C. A., Dudakovic, A., van Genechten, W., Hewett, T., Kakar, S., Krych, A. J., van Wijnen, A. J. & Saris, D., 19 Mar 2019, In : Tissue Engineering Part C: Methods. 25, 4, p. 191-196 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Anterior Cruciate Ligament Reconstruction
Ligaments
Anterior Cruciate Ligament
Rabbits
Animal Care Committees

Benchmark on automatic 6-month-old infant brain segmentation algorithms: The iSeg-2017 Challenge

Wang, L., Nie, D., Li, G., Puybareau, E., Dolz, J., Zhang, Q., Wang, F., Xia, J., Wu, Z., Chen, J., Thung, K-H., Bui, T. D., Shin, J., Zeng, G., Zheng, G., Fonov, V. S., Doyle, A., Xu, Y., Moeskops, P., Pluim, J. P. W. & 9 othersDesrosiers, C., Ayed, I. B., Sanroma, G., Benkarim, O. M., Casamitjana, A., Vilaplana, V., Lin, W., Li, G. & Shen, D., 27 Feb 2019, In : IEEE Transactions on Medical Imaging.

Research output: Contribution to journalArticleAcademicpeer-review

Benchmarking
Brain
Magnetic resonance
Magnetic Resonance Spectroscopy
Cerebrospinal fluid

Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration

Castilho, M., Mouser, V., Chen, M., Malda, J. & Ito, K., 22 Jun 2019, In : Acta Biomaterialia.

Research output: Contribution to journalArticleAcademicpeer-review

Hydrogels
Cartilage
Articular Cartilage
Regeneration
Fibers

Biomorphic engineering of multifunctional polylactide stomatocytes toward therapeutic nano-red blood cells

Shao, J., Pijpers, I. A. B., Cao, S., Williams, D. S., Yan, X., Li, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 1 Jan 2019, In : Advanced Science. 6, 5, 8 p., 1801678

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
erythrocytes
Blood
Erythrocytes
Cells
engineering

Bone microarchitecture and distal radius fracture pattern complexity

Daniels, A. M., Theelen, L. M. A., Wyers, C. E., Janzing, H. M. J., van Rietbergen, B., Vranken, L., van der Velde, R. Y., Geusens, P. P. M. M., Kaarsemaker, S., Poeze, M. & van den Bergh, J. P., 12 Apr 2019, In : Journal of Orthopaedic Research.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Radius Fractures
Bone Density
Bone and Bones
Joints
Odds Ratio
3 Citations (Scopus)

Carbon nanotube reinforced supramolecular hydrogels for bioapplications

Mihajlovic, M., Mihajlovic, M., Dankers, P. Y. W., Masereeuw, R. & Sijbesma, R. P., 1 Jan 2019, In : Macromolecular Bioscience. 19, 12 p., 1800173

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Carbon Nanotubes
Hydrogels
Nanocomposites
Carbon nanotubes
Hydrogel

Cardiomyocyte contractile force changes in response to AGRWE detected by AFM

Qu, Y. M., Zhao, F., Wang, X., Liu, J., Li, J., Song, Z. & Wang, Z., 2 May 2019, In : Micro and Nano Letters. 14, 5, p. 511-514 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

atomic force microscopy
Water
water
synchronism
heart rate

Cats or CAT scans: transfer learning from natural or medical image source data sets?

Cheplygina, V., Mar 2019, In : Current Opinion in Biomedical Engineering. 9, p. 21-27

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
learning
tomography
image analysis
train
Heart Valves
Advisory Committees
Thoracic Surgery
Thorax
Organizations

Characteristics of surgical prosthetic heart valves and problems around labelling: a document from the European Association for Cardio-Thoracic Surgery (EACTS)-the society of thoracic surgeons (STS)-american association for thoracic surgery (AATS) valve labelling task force

Durko, A. P., Head, S. J., Pibarot, P., Atluri, P., Bapat, V., Cameron, D. E., Casselman, F. P. A., Chen, E. P., Dahle, G., Ebels, T., Elefteriades, J. A., Lancellotti, P., Prager, R. L., Rosenhek, R., Speir, A., Stijnen, M., Tasca, G., Yoganathan, A., Walther, T. & de Paulis, R., 1 Jun 2019, In : European Journal of Cardio-Thoracic Surgery. 55, 6, p. 1025-1036 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Heart Valves
Advisory Committees
Thoracic Surgery
Thorax
Organizations

CHD1 loss alters AR binding at lineage-specific enhancers and modulates distinct transcriptional programs to drive prostate tumorigenesis

Augello, M. A., Liu, D., Deonarine, L. D., Robinson, B. D., Huang, D., Stelloo, S., Blattner, M., Doane, A. S., Wong, E. W. P., Chen, Y., Rubin, M. A., Beltran, H., Elemento, O., Bergman, A. M., Zwart, W., Sboner, A., Dephoure, N. & Barbieri, C. E., 15 Apr 2019, In : Cancer Cell. 35, 4, p. 603-617

Research output: Contribution to journalArticleAcademicpeer-review

Androgen Receptors
Prostate
Carcinogenesis
Neoplasms
Prostatic Neoplasms

Chemoenzymatic synthesis of sialic acid derivatives using immobilized N-acetylneuraminate lyase in a continuous flow reactor

Bloemendal, V. R. L. J., Moons, S. J., Heming, J. J. A., Chayoua, M., Niesink, O., van Hest, J. C. M., Boltje, T. J. & Rutjes, F. P. J. T., 8 May 2019, In : Advanced Synthesis and Catalysis. 361, 11, p. 2443-2447

Research output: Contribution to journalArticleAcademicpeer-review

N-acetylneuraminate lyase
N-Acetylneuraminic Acid
Derivatives
Acids
Sialic Acids

Clinical interpretation of prostate-specific antigen values: type of applied cut-off value exceeds methods bias as the major source of variation

Klinkenberg, L. J. J., Lentjes, E. G. W. M. & Boer, A. K., 1 Mar 2019, In : Annals of Clinical Biochemistry. 56, 2, p. 259-265 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prostate-Specific Antigen
Prostatic Neoplasms
Biopsy
Linear regression
Standardization

Comparing signal-to-noise ratio for prostate imaging at 7T and 3T

Steensma, B. R., Luttje, M., Voogt, I. J., Klomp, D. W. J., Luijten, P. R., van den Berg, C. A. T. & Raaijmakers, A. J. E., May 2019, In : Journal of Magnetic Resonance Imaging. 49, 5, p. 1446-1455

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Signal-To-Noise Ratio
Prostate
Volunteers
Neoplasms
Protons

Computational modelling of energy balance in individuals with Metabolic Syndrome

Rozendaal, Y., Wang, Y., Hilbers, P. & van Riel, N., 26 Feb 2019, In : BMC Systems Biology. 13, 24, 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Computational Modeling
Energy Balance
Energy balance
Energy Metabolism
Energy

Cooperativity basis for small-molecule stabilization of protein-protein interactions

de Vink, P. J., Andrei, S. A., Higuchi, Y., Ottmann, C., Milroy, L-G. & Brunsveld, L., 2019, In : Chemical Science. 10, 10, p. 2869-2874 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Stabilization
Molecules
Proteins
14-3-3 Proteins
Fluorescence
9 Citations (Scopus)

Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study

Samelson, E. J., Broe, K. E., Xu, H., Yang, L., Boyd, S., Biver, E., Szulc, P., Adachi, J., Amin, S., Atkinson, E., Berger, C., Burt, L., Chapurlat, R., Chevalley, T., Ferrari, S., Goltzman, D., Hanley, D. A., Hannan, M. T., Khosla, S., Liu, C-T. & 13 othersLorentzon, M., Mellstrom, D., Merle, B., Nethander, M., Rizzoli, R., Sornay-Rendu, E., van Rietbergen, B., Sundh, D., Wong, A. K. O., Ohlsson, C., Demissie, S., Kiel, D. P. & Bouxsein, M. L., 1 Jan 2019, In : Lancet Diabetes & Endocrinology. 7, 1, p. 34-43 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bone Density
Prospective Studies
Bone and Bones
Femur Neck
Tibia

Counterion dependent mechanisms of DNA origami nanostructure stabilization revealed by atomistic molecular simulation

Roodhuizen, J., Hendrikx, P. J. T. M., Hilbers, P. A. J., de Greef, T. & Markvoort, B., 2019, (Accepted/In press) In : ACS Nano.

Research output: Contribution to journalArticleAcademicpeer-review

Cyclic strain affects macrophage cytokine secretion and ECM turnover in electrospun scaffolds

Bonito, V., de Kort, B., Bouten, C. & Smits, A. I. P. M., 27 Feb 2019, In : Tissue engineering. Part A.

Research output: Contribution to journalArticleAcademicpeer-review

Military electronic countermeasures
Macrophages
Scaffolds (biology)
Cytokines
Tissue Engineering
1 Citation (Scopus)

Development of morphologically discrete PEG-PDLLA nanotubes for precision nanomedicine

Wauters, A. C., Pijpers, I. A. B., Mason, A. F., Williams, D. S., Tel, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 1 Jan 2019, In : Biomacromolecules. 20, 1, p. 177-183

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Medical nanotechnology
Nanotubes
Polyethylene glycols
Particle interactions
Nanostructures
2 Citations (Scopus)

DNA-based communication in populations of synthetic protocells

Joesaar, A. H., Yang, S., Bögels, B. W. A., van der Linden, A. J., Pieters, P. A., Kumar, P., Dachau, N., Phillips, A., Mann, S. & de Greef, T. F. A., 1 Apr 2019, In : Nature Nanotechnology. 14, p. 369-378

Research output: Contribution to journalArticleAcademicpeer-review

DNA
deoxyribonucleic acid
communication
Communication
Networks (circuits)

Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns

Beijer, N. R. M., Nauryzgaliyeva, Z. M., Arteaga, E. M., Pieuchot, L., Anselme, K., van de Peppel, J., Vasilevich, A. S., Groen, N., Roumans, N., Hebels, D. G. A. J. & Boer, J. D., 1 Dec 2019, In : Scientific Reports. 9, 1, 14 p., 9099

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cell Physiological Phenomena
Mesenchymal Stromal Cells
Polystyrenes
Stem Cell Transplantation
Paclitaxel
5 Citations (Scopus)

Early or delayed cardioversion in recent-onset atrial fibrillation

Pluymaekers, N. A. H. A., Dudink, E. A. M. P., Luermans, J. G. L. M., Meeder, J. G., Lenderink, T., Widdershoven, J., Bucx, J. J. J., Rienstra, M., Kamp, O., Van Opstal, J. M., Alings, M., Oomen, A., Kirchhof, C. J., van Dijk, V. F., Ramanna, H., Liem, A., Dekker, L. R., Essers, B. A. B., Tijssen, J. G. P., Van Gelder, I. C. & 1 othersCrijns, H. J. G. M., 18 Apr 2019, In : New England Journal of Medicine. 380, 16, p. 1499-1508 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Electric Countershock
Atrial Fibrillation
Hospital Emergency Service
Confidence Intervals
Random Allocation

Echocardiographic assessment of left bundle branch–related strain dyssynchrony: a comparison with tagged MRI

Fixsen, L. S., de Lepper, A. G. W., Strik, M., van Middendorp, L. B., Prinzen, F. W., van de Vosse, F. N., Houthuizen, P. & Lopata, R. G. P., 3 May 2019, In : Ultrasound in Medicine and Biology.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
echocardiography
bundles
Echocardiography
Software
computer programs

Entropic forces drive cellular contact guidance

Buskermolen, A. B. C., Suresh, H., Shishvan, S. S., Vigliotti, A., DeSimone, A., Kurniawan, N. A., Bouten, C. V. C. & Deshpande, V. S., 21 May 2019, In : Biophysical Journal. 116, 10, p. 1994-2008 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Stress Fibers
Entropy
Cell Size
Cell Nucleus Shape
Cell Nucleus Size
4 Citations (Scopus)

Epileptic seizure detection in EEG signals using sparse multiscale radial basis function networks and the Fisher vector approach

Li, Y., Cui, W. G., Huang, H., Guo, Y. Z., Li, K. & Tan, T., 15 Jan 2019, In : Knowledge-Based Systems. 164, p. 96-106

Research output: Contribution to journalArticleAcademicpeer-review

Radial basis function networks
Electroencephalography
Statistical tests
Model structures
Particle swarm optimization (PSO)

Equilibrium model for supramolecular copolymerizations

ten Eikelder, H., Adelizzi, B., Palmans, A. & Markvoort, B., 19 Jun 2019, In : Journal of Physical Chemistry B.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Copolymerization
Copolymers
Monomers
Free energy
Polymers

Ex vivo pilot study of cardiac magnetic resonance velocity mapping for quantification of aortic regurgitation in a porcine model in the presence of a transcatheter heart valve

Kooistra, N. H. M., Nijhoff, F., Abawi, M., Agostoni, P., Araya Roos, D. M., van Tuijl, S., Blanken, N., Voskuil, M., Doevendans, P. A. F. M., Stella, P. R. & Leiner, T., 1 Jan 2019, In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Aortic Valve Insufficiency
Heart Valves
Magnetic Resonance Spectroscopy
Swine
Magnetic Resonance Imaging

Feasibility and safety of jailed-pressure wire technique using durable optical fiber pressure wire for intervention of coronary bifurcation lesions

Omori, H., Kawase, Y., Hara, M., Tanigaki, T., Okamoto, S., Hirata, T., Kikuchi, J., Ota, H., Sobue, Y., Miyake, T., Kawamura, I., Okubo, M., Kamiya, H., Tsuchiya, K., Suzuki, T., Pijls, N. H. J. & Matsuo, H., 5 Feb 2019, In : Catheterization and Cardiovascular Interventions.

Research output: Contribution to journalArticleAcademicpeer-review

Optical Fibers
Safety
Pressure
Dilatation
Stable Angina
1 Citation (Scopus)

Fourier transform on the homogeneous space of 3D positions and orientations for exact solutions to linear PDEs

Duits, R., Bekkers, E. J. & Mashtakov, A., 8 Jan 2019, In : Entropy. 21, 1, 38 p., 38

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
pulse detonation engines
quotients
rigid structures
robotics
image analysis