Department of Biomedical Engineering

Research Output 1962 2020

4 Citations (Scopus)

The potential of prolonged tissue culture to reduce stress generation and retraction in engineered heart valve tissues

Vlimmeren, van, M. A. A., Driessen - Mol, A., Oomens, C. W. J. & Baaijens, F. P. T., 2013, In : Tissue Engineering. Part C: Methods. 19, 3, p. 205-215 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue culture
Heart Valves
Tissue
Glycosaminoglycans
Compaction

The potential therapeutic gain of redisributing dose to hypoxic regions using dose-painting: a modeling study

Petit, S. F., Riel, van, N. A. W., Murrer, L. H. P., Seigneuric, R., Lambin, P. & Wouters, B. G., 2005, Proc. 8th Biennial ESTRO Meeting on Physics and Radiation Technology for Clinical Radiotherapy. Lisbon, Portugal

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

The potential therapeutic gain of redistributing dose to hypoxic regions using dose-painting: a modeling study

Petit, S. F., Riel, van, N. A. W., Murrer, L. H. P., Seigneuric, R., Lambin, P. & Wouters, B. G., 2006, 8th Biennial ESTRO Meeting on Physics and Radiation Technology for Clinical Radiotherapy. Portugal, Lisboa

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

10 Citations (Scopus)
29 Downloads (Pure)

The predictability of visual outcome of epiretinal membrane peeling by pre-operative OCT images

Takkenberg, D. E. J., Berendschot, T. T. J. M. & Goezinne, F., Mar 2018, In : Acta Ophthalmologica. 96, p. 9-9

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
File
128 Citations (Scopus)

The pro-angiogenic properties of multi-functional bioactive glass composite scaffolds

Gerhardt, L. C., Widdows, K. L., Erol, M. M., Burch, C. W., Sanz-Herrera, J. A., Ochoa, I., Staempfli, R., Roqan, I. S., Gabe, S., Ansari, T. & Boccaccini, A. R., 2011, In : Biomaterials. 32, 17, p. 4096-4108 4096 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bioactive glass
Scaffolds
Glass
Composite materials
Composite films
46 Citations (Scopus)

The prognostic value of residual coronary stenoses after functionally complete revascularization

FAME Study Investigators, 12 Apr 2016, In : Journal of the American College of Cardiology. 67, 14, p. 1701-1711 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Coronary Stenosis
Percutaneous Coronary Intervention
Angiography
Kaplan-Meier Estimate
Coronary Artery Disease
6 Citations (Scopus)

The prognostic value of right ventricular deformation imaging in early arrhythmogenic right ventricular cardiomyopathy

Mast, T. P., Taha, K., Cramer, M. J., Lumens, J., van der Heijden, J. F., Bouma, B. J., van den Berg, M. P., Asselbergs, F. W., Doevendans, P. A. & Teske, A. J., 1 Mar 2019, In : JACC: Cardiovascular Imaging. 12, 3, p. 446-455 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Arrhythmogenic Right Ventricular Dysplasia
Advisory Committees
Disease Progression
Confidence Intervals
27 Citations (Scopus)
1 Downloads (Pure)

The prospects of estimating trabecular bone tissue properties from the combination of ultrasound, dual-energy X-ray absorptiometry, microcomputed tomography, and microfinite element analysis

Lenthe, van, G. H., Bergh, van den, J. P. W., Hermus, A. R. M. M. & Huiskes, H. W. J., 2001, In : Journal of Bone and Mineral Research. 16, 3, p. 550-555

Research output: Contribution to journalArticleAcademicpeer-review

X-Ray Microtomography
Photon Absorptiometry
Bone and Bones
Elastic Modulus
Bone Density
22 Downloads (Pure)

The prospects of estimating trabecular-bone tissue properties from ultrasound, micro-CT and micro-finite element analysis

Lenthe, van, G. H., Bergh, van den, J. P. W., Hermus, A. R. M. M. & Huiskes, H. W. J., 1999, 45th Annual meeting of the Orthopaedic Research Society. S.l.: Orthopaedic Research Society, p. 570

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
File
30 Citations (Scopus)
Hypertrophy
Parathyroid Hormone-Related Protein
Growth Plate
Feedback Loop
Proliferation
92 Citations (Scopus)
4 Downloads (Pure)

The quality of trabecular bone evaluated with micro-computed tomography, FEA and mechanical testing

Ulrich, D., Hildebrand, T., Rietbergen, van, B., Müller, R. & Rüegsegger, P., 1997, Bone research in biomechanics. Lowet, G., Rüegsegger, P. & Weinans, H. (eds.). Amsterdam: IOS Press, p. 97-112 (Studies in health technology and informatics; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Mechanical testing
Tomography
Bone
Finite element method
Volume fraction
25 Citations (Scopus)

The quantitation of ADP diffusion gradients across the outer membrane of heart mitochondria in the presence of macromolecules

Gellerich, F. N., Laterveer, F. D., Zierz, S. & Nicolaij, K., 2002, In : Biochimica et Biophysica Acta, Bioenergetics. 1554, 1-2, p. 48-56

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Heart Mitochondria
Mitochondria
Macromolecules
Adenosine Diphosphate
Membranes
28 Citations (Scopus)
40 Downloads (Pure)

The R439C mutation in LMNA causes lamin oligomerization and susceptibility to oxidative stress

Verstraeten, V. L. R. M., Caputo, S., Van Steensel, M. A. M., Duband-Goulet, I., Zinn-Justin, S., Kamps, M. A. F., Kuijpers, H. J. H., Östlund, C., Worman, H. J., Briedé, J. J., Le Dour, C., Marcelis, C. L. M., Van Geel, M., Steijlen, P. M., Van Den Wijngaard, A., Ramaekers, F. C. S. & Broers, J. L. V., May 2009, In : Journal of Cellular and Molecular Medicine. 13, 5, p. 959-971 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Familial Partial Lipodystrophy
Lamins
Lamin Type A
Oxidative Stress
Mutation
12 Citations (Scopus)
54 Downloads (Pure)

Therapeutic drug monitoring (TDM) as a tool in the switch from infliximab innovator to biosimilar in rheumatic patients: results of a 12-month observational prospective cohort study

Schmitz, E. M. H., Benoy-De Keuster, S., Meier, A. J. L., Scharnhorst, V., Traksel, R. A. M., Broeren, M. A. C. & Derijks, L. J. J., 1 Sep 2017, In : Clinical Rheumatology. 36, 9, p. 2129-2134 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Biosimilar Pharmaceuticals
Drug Monitoring
Cohort Studies
Prospective Studies
Infliximab
20 Citations (Scopus)

Therapeutic drug monitoring of infliximab : performance evaluation of three commercial ELISA kits

Schmitz, E. M. H., van de Kerkhof, D., Hamann, D., van Dongen, J. L. J., Kuijper, P. H. M., Brunsveld, L., Scharnhorst, V. & Broeren, M. A. C., 2016, In : Clinical Chemistry and Laboratory Medicine. 54, 7, p. 1211–1219

Research output: Contribution to journalArticleAcademicpeer-review

Drug Monitoring
Assays
Enzyme-Linked Immunosorbent Assay
Monitoring
Pharmaceutical Preparations

Therapeutic drug monitoring van adalimumab bij patiënten met inflammatoire darmziekten

Translated title of the contribution: Therapeutic drug monitoring of adalimumab in inflammatory bowel disease patientsvan 't Geloof, W., Boekema, P. J., Gilissen, L. P. L., Broeren, M. A. C. & Derijks, L. J. J., 15 Mar 2019, In : Pharmaceutisch Weekblad. 154, 11, p. 29-32 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Drug Monitoring
Inflammatory Bowel Diseases
Adalimumab
Outpatients
Quality of Life

Therapeutic drug monitoring van adalimumab bij reumatologische patiënten

Translated title of the contribution: Therapeutic drug monitoring of adalimumab in rheumatic patientsKylstra, A. H., Benoy-de Keuster, S., Traksel, R. A. M., Broeren, M. A. C. & Derijks, L. J. J., 8 Feb 2019, In : Pharmaceutisch Weekblad. 154, 6, p. 25-28 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Drug Monitoring
Adalimumab
Hospital Information Systems
Psoriatic Arthritis
Ankylosing Spondylitis
146 Citations (Scopus)

Therapeutic intervention based on protein prenylation and associated modifications

Gelb, M. H., Brunsveld, L., Hrycyna, C. A., Michaelis, S. & Tamanoi, F., 2006, In : Nature Chemical Biology. 2, 10, p. 518-528

Research output: Contribution to journalArticleAcademicpeer-review

Protein Prenylation
Carbon
Protein C
Progeria
Protozoan Infections
34 Citations (Scopus)
330 Downloads (Pure)

Therapeutic potential of adipose-derived stromal cells in age-related osteoporosis

Mirsaidi, A., Genelin, K., Vetsch, J. R., Stanger, S., Theiss, F., Lindtner, R. A., von Rechenberg, B., Blauth, M., Müller, R., Kuhn, G., Hofmann, S., Ebner, H. L. & Richards, P. J., 2014, In : Biomaterials. 35, 26, p. 7326-7335 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Stromal Cells
Osteoporosis
Bone
Scaffolds
Tomography
18 Citations (Scopus)

Therapeutic targeting of trained immunity

Mulder, W. J. M., Ochando, J., Joosten, L. A. B., Fayad, Z. A. & Netea, M. G., 9 Apr 2019, In : Nature Reviews Drug Discovery. 18, 7, p. 553-566 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Immunity
Immunotherapy
Immune System
Immune System Diseases
Myeloid Cells
66 Citations (Scopus)

The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion

Gruijthuijsen, Y. K., Casarosa, P., Kaptein, S. J. F., Broers, J. L. V., Leurs, R., Bruggeman, C. A., Smit, M. J. & Vink, C., 2002, In : Journal of virology. 76, 3, p. 1328-1338

Research output: Contribution to journalArticlePopular

Murid herpesvirus 2
Muromegalovirus
pertussis toxin
phospholipase C
Pertussis Toxin
2 Downloads (Pure)

The ratio between tissue and scaffold in cardiovascular tissue engineering

Soekhradj - Soechit, R. S., Driessen - Mol, A., Hoerstrup, S. P. & Baaijens, F. P. T., 2010.

Research output: Contribution to conferencePosterAcademic

3 Citations (Scopus)
58 Downloads (Pure)

The regenerative potential of notochordal cells in a nucleus pulposus explant

Arkesteijn, I. T. M., Potier, E. & Ito, K., 1 Feb 2017, In : Global Spine Journal. 7, 1, p. 14-20 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
A73025
Phosphates
Nucleus Pulposus
DNA
Hydroxyproline
30 Downloads (Pure)

The regulation of functional adaptation in trabecular bone

Mullender, M. G. & Huiskes, H. W. J., 1995, Bone structure and remodeling / Ed. A. Odgaard, H. Weinans. Singapore: World Scientific, p. 181-187 (Recent advances in human biology; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingChapterPopular

Open Access
File
2 Downloads (Pure)

There is an individual tolerance to mechanical loading in compression induced deep tissue injury

Traa, W. A., van Turnhout, M. C., Nelissen, J. L., Strijkers, G. J., Bader, D. L. & Oomens, C. W. J., 1 Mar 2019, In : Clinical Biomechanics. 63, p. 153-160 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pressure Ulcer
Wounds and Injuries
Edema
Muscles
6 Citations (Scopus)

The relation between cardiac output kinetics and skeletal muscle oxygenation during moderate exercise in moderately impaired patients with chronic heart failure

Spee, R. F., Niemeijer, V. M., Schoots, T., Wijn, P. F. F., Doevendans, P. A. F. M. & Kemps, H. M. C., 1 Jul 2016, In : Journal of Applied Physiology. 121, 1, p. 198-204 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cardiac Output
Skeletal Muscle
Heart Failure
Exercise
Oxygen
4 Citations (Scopus)
48 Downloads (Pure)

The relationship between fractional flow reserve, platelet reactivity and platelet leukocyte complexes in stable coronary artery disease

Sels, J. W. E. M., Rutten, B., Holten, van, T. C., Hillaert, M. A. K., Waltenberger, J., Pijls, N. H. J., Pasterkamp, G., Groot, de, P. G. & Roest, M., 2013, In : PLoS ONE. 8, 12, p. e83198-1/7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Platelets
Coronary Artery Disease
leukocytes
Leukocytes
Blood Platelets
92 Downloads (Pure)

The relationship between knee motion and articular surface geometry

Huiskes, R. & Blankevoort, L., 1990, Biomechanics of diarthrodial joints, volume 2. Mow, V. C., Ratcliffe, A. & Woo, SL-Y. (eds.). New York: Springer, p. 269-286

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Open Access
File
Knee
Joints
6 Downloads (Pure)

The relationship between loading rate and damage (Keynote)

Donkelaar, van, C. C., Parraga Quiraga, J. M., Henao Murillo, L. & Ito, K., 2014, 7th World Congress of Biomechanics, July 6-11, 2014, Boston, Massachusetts, USA.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

18 Citations (Scopus)

The relationship between local scalp skin temperature and cutaneous perfusion during scalp cooling

Janssen, F. E. M., Rajan, V., Steenbergen, W., Leeuwen, van, G. M. J. & Steenhoven, van, A. A., 2007, In : Physiological Measurement. 28, 8, p. 829-839

Research output: Contribution to journalArticleAcademicpeer-review

Skin Temperature
Scalp
Skin
Perfusion
Cooling

The relationship between proteoglycan loss, overloading-induced collagen damage, and cyclic loading in articular cartilage

Henao Murillo, L., Pastrama, M., Ito, K. & van Donkelaar, R., 15 Nov 2019, In : Cartilage.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cartilage
Articular Cartilage
Proteoglycans
Collagen
Phosphates
1 Downloads (Pure)

The relationship between softening and collagen fibril damage

Henao Murillo, L., Ito, K. & Donkelaar, van, C. C., 2012.

Research output: Contribution to conferencePosterAcademic

720 Citations (Scopus)
573 Downloads (Pure)

The relationship between stress shielding and bone resorption around total hip stems and the effects of flexible materials

Huiskes, H. W. J., Weinans, H. & Rietbergen, van, B., 1992, In : Clinical Orthopaedics and Related Research. 274, p. 124-134

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Bone Resorption
Hip
Bone and Bones
Bone Remodeling
Individuality
127 Citations (Scopus)
1 Downloads (Pure)

The relative contributions of compression and hypoxia to development of muscle tissue damage: an in vitro study

Gawlitta, D., Li, W., Oomens, C. W. J., Baaijens, F. P. T., Bader, D. L. & Bouten, C. V. C., 2007, In : Annals of Biomedical Engineering. 35, 2, p. 273-284

Research output: Contribution to journalArticleAcademicpeer-review

Cell death
Muscle
Compaction
Tissue
Cells
177 Citations (Scopus)
1 Downloads (Pure)

The relative contributions of different skin layers to the mechanical behaviour of human skin in vivo using suction experiments

Hendriks, F. M., Brokken, D., Oomens, C. W. J., Bader, D. L. & Baaijens, F. P. T., 2006, In : Medical Engineering & Physics. 28, 3, p. 259-266

Research output: Contribution to journalArticleAcademicpeer-review

Suction
Skin
Dermis
Epidermis
Experiments
483 Downloads (Pure)

The relative contributions of muscle deformation and ischaemia to pressure ulcer development

Loerakker, S., 2011, Eindhoven: Technische Universiteit Eindhoven. 162 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
File
Pressure Ulcer
Ischemia
Muscles
Wounds and Injuries
Myoglobin

The relative contributions of muscle deformation and ischaemia to pressure ulcer development

Loerakker, S., Strijkers, G. J., Nicolay, K., Baaijens, F. P. T., Bader, D. L. & Oomens, C. W. J., 2012, Proceedings of the ASME summer bioengineering conference, pts A and B. p. 375-376 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

The relevance of collagen cross-links for mechanical behavior of human aortic valve leaflets – Prospects for tissue engineering

Balguid, A., Driessen - Mol, A., Bouten, C. V. C. & Baaijens, F. P. T., 2006, TERMIS 2007. Netherlands, Rotterdam, p. 1-

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

6 Downloads (Pure)

The relevance of extracellular matrix structure and composition in engineering the diseased cardiac microenvironment

Spreeuwel, van, A. C. C., Bax, N. A. M. & Bouten, C. V. C., 2014, In : OA Tissue Engineering. 2, 1, p. 1-6

Research output: Contribution to journalArticleAcademicpeer-review

60 Downloads (Pure)

The relevance of high strains in tissue engineering of heart valves

Driessen - Mol, A., Hoerstrup, S. P., Bouten, C. V. C., Visjager, J. F., Guenter, C., Zund, G., Turina, M. I. & Baaijens, F. P. T., 2002.

Research output: Contribution to conferencePosterAcademic

Open Access
File
20 Downloads (Pure)

The relevance of implant telemetry for mechanical analyses of total hip arthroplasties

Verdonschot, N. J. J., Dalstra, M. & Huiskes, H. W. J., 1990, Implantable telemetry in orthopaedics : workshop : papers. Bergmann, G., Graichen, F. & Rohlmann, A. (eds.). Berlin: Freie Universität Berlin, p. 249-257

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
File
82 Citations (Scopus)
3 Downloads (Pure)

The relevance of large strains in functional tissue engineering of heart valves

Driessen - Mol, A., Bouten, C. V. C., Zund, G., Günter, C. I., Visjager, J. F., Turina, M. I., Baaijens, F. P. T. & Hoerstrup, S. P., 2003, In : Thoracic and Cardiovascular Surgeon. 51, 2, p. 78-83

Research output: Contribution to journalArticleAcademicpeer-review

Heart Valves
Tissue Engineering
Pressure
Pulmonary Valve
Bioreactors
21 Citations (Scopus)
120 Downloads (Pure)

The relevance of non-generic events in scale space models

Kuijper, A. & Florack, L. M. J., 2004, In : International Journal of Computer Vision. 57, 1, p. 67-84

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Trajectories

The relevance of non-generic events in scale space models

Kuijper, A. & Florack, L. M. J., 2001, Utrecht: Utrecht University. (UU-CS; vol. 2001-55)

Research output: Book/ReportReportAcademic

trajectory
catastrophe theory
modeling
5 Citations (Scopus)

The relevance of non-generic events in scale space models

Kuijper, A. & Florack, L. M. J., 2002, Proceedings of the 7th European Conference on Computer Vision, Part I (ECCV 2002), 28-31 May 2002, Copenhagen, Denmark. Heyden, A., Sparr, G., Nielsen, M. & Johansen, P. (eds.). Berlin, Germany: Springer, p. 190-204 (Lecture Notes in Computer Science; vol. 2350).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

catastrophe theory
trajectory
5 Citations (Scopus)
46 Downloads (Pure)

The reliability of a semi-automated algorithm for detection of cortical interruptions in finger joints on high resolution CT compared to microCT

Peters, M., Scharmga, A., van Tubergen, A., Arts, J., Loeffen, D., Weijers, R., van Rietbergen, B., Geusens, P. P. M. M. & van den Bergh, J. P. W., 25 Jul 2017, In : Calcified Tissue International. 101, 2, p. 132–140 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Finger Joint
X-Ray Microtomography
Joints
Tomography
Fingers
2 Citations (Scopus)
1 Downloads (Pure)

The reliability of continuous measurement of mixed venous oxygen saturation during exercise in patients with chronic heart failure

Sleutjes, B. T. H. M., Kemps, H. M. C., Thijssen, E. J. M., Vosse, van de, F. N., Schep, G., Peters, C. H. L. & Wijn, P. F. F., 2008, In : European Journal of Applied Physiology. 102, 4, p. 493-496

Research output: Contribution to journalArticleAcademicpeer-review

Heart Failure
Exercise
Oxygen
Catheters
Pulmonary Artery
13 Citations (Scopus)
82 Downloads (Pure)

The renaissance of Ras

Milroy, L. G. & Ottmann, C., 2014, In : ACS Chemical Biology. 9, 11, p. 2447-2458 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Oncology
Monomeric GTP-Binding Proteins
Drug Discovery
Proteins
Mutation
13 Citations (Scopus)

The representation and matching of images using top points

Demirci, M. F., Platel, B., Shokoufandeh, A., Florack, L. M. J. & Dickinson, S. J., 2009, In : Journal of Mathematical Imaging and Vision. 35, 2, p. 103-116

Research output: Contribution to journalArticleAcademicpeer-review

Scale Space
Matching Algorithm
embedding
Experiments
Experiment
48 Downloads (Pure)

The reproducibility of passive human knee-joint motion characteristics

Blankevoort, L., Huiskes, H. W. J. & Lange, de, A., 1985, Biomechanics : current interdisciplinary research : selected proceedings of the fourth meeting of the European Society of Biomechanics / Ed. S.M. Perren, E. Schneider. Dordrecht: Nijhoff, p. 3091-3314 (Developments in biomechanics; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
File