Department of Biomedical Engineering

Research Output

2018

Publisher correction: Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Tanaka, N., Kanatani, S., Tomer, R., Sahlgren, C., Kronqvist, P., Kaczynska, D., Louhivuori, L., Kis, L., Lindh, C., Mitura, P., Stepulak, A., Corvigno, S., Hartman, J., Micke, P., Mezheyeuski, A., Strell, C., Carlson, J. W., Fernández Moro, C., Dahlstrand, H., Östman, A. & 6 others, Matsumoto, K., Wiklund, P., Oya, M., Miyakawa, A., Deisseroth, K. & Uhlén, P., 2 Jan 2018, In : Nature Biomedical Engineering. 2, 1, p. 48 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access
1 Citation (Scopus)

Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization

Ksiazek, A. A., Frese, L., Dijkman, P. E., Sanders, B., Motta, S. E., Weber, B. & Hoerstrup, S. P., 15 Apr 2018, In : Acta Biomaterialia. 71, p. 474-485 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
Open Access

Quantifying the effect of structural manipulations on cellular stress generation

van Loosdregt, I. A. E. W., 23 Jan 2018, Eindhoven: Technische Universiteit Eindhoven. 113 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
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118 Downloads (Pure)

Rational design, binding studies and crystal structure evaluation of the first ligand targeting the dimerization Interface of the 14-3-3ζ adapter protein

Ehlers, M., Grad, J. N., Mittal, S., Bier, D., Mertel, M., Ohl, L., Bartel, M., Briels, J., Heimann, M., Ottmann, C., Sanchez-Garcia, E., Hoffmann, D. & Schmuck, C., 16 Mar 2018, In : ChemBioChem. 19, 6, p. 591-595 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Rationally designed semisynthetic natural product analogues for stabilization of 14-3-3 protein–protein interactions

Andrei, S. A., de Vink, P., Sijbesma, E., Han, L., Brunsveld, L., Kato, N., Ottmann, C. & Higuchi, Y., 8 Oct 2018, In : Angewandte Chemie - International Edition. 57, 41, p. 13470-13474 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)
2 Downloads (Pure)

Reconnection of interrupted curvilinear structures via cortically inspired completion for ophthalmologic images

Zhang, J., Bekkers, E., Chen, D., Berendschot, T. T. J. M., Schouten, J., Pluim, J. P. W., Shi, Y., Dashtbozorg, B. & Romeny, B. M. T. H., 1 May 2018, In : IEEE Transactions on Biomedical Engineering. 65, 5, p. 1151-1165 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Reference values for anterior chamber morphometrics with swept-source optical coherence tomography in a Caucasian population

Romkens, H. C. S., Beckers, H. J. M., Schouten, J. S. A. G., Berendschot, T. T. J. M. & Webers, C. A. B., 28 Feb 2018, In : Clinical Ophthalmology. 12, p. 411-417 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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52 Downloads (Pure)

Regulation of cell cycle progression by cell-cell and cell-matrix forces

Uroz, M., Wistorf, S., Serra-Picamal, X., Conte, V., Sales-Pardo, M., Roca-Cusachs, P., Guimerà, R. & Trepat, X., 1 Jun 2018, In : Nature Cell Biology. 20, 6, p. 646-654 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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25 Citations (Scopus)
28 Downloads (Pure)

Residue-specific incorporation of noncanonical amino acids for protein engineering

van Eldijk, M. B. & van Hest, J. C. M., 2018, Noncanonical amino acids: methods and protocols. Lemke, E. A. (ed.). New York: Humana Press, p. 137-145 9 p. (Methods in Molecular Biology; vol. 1728).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)

Retinal artery/vein classification using genetic-search feature selection

Huang, F., Dashtbozorg, B., Tan, T. & ter Haar Romeny, B. M., 1 Jul 2018, In : Computer Methods and Programs in Biomedicine. 161, p. 197-207 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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14 Citations (Scopus)
69 Downloads (Pure)

Retinal microaneurysms detection using local convergence index features

Dashtbozorg, B., Zhang, J., Huang, F. & ter Haar Romeny, B. M., Jul 2018, In : IEEE Transactions on Image Processing. 27, 7, p. 3300-3315 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)
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94 Downloads (Pure)

Roto-translation covariant convolutional networks for medical image analysis

Bekkers, E. J., Lafarge, M. W., Veta, M., Eppenhof, K. A. J., Pluim, J. P. W. & Duits, R., 1 Jan 2018, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Schnabel, J. A., Davatzikos, C., Alberola-López, C., Fichtinger, G. & Frangi, A. F. (eds.). Cham: Springer, p. 440-448 9 p. (Lecture Notes in Computer Science; vol. 11070).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

9 Citations (Scopus)

Selection strategies for atlas-based mosaicing of left atrial 3-D transesophageal echocardiography data

Mulder, H. W., van Stralen, M., Ren, B., Haak, A., van Burken, G., Viergever, M. A., Bosch, J. G. & Pluim, J. P. W., Jul 2018, In : Ultrasound in Medicine and Biology. 44, 7, p. 1533–1543 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Self-assembled nanoreactors based on peptides and proteins

Timmermans, S. B. P. E. & van Hest, J. C. M., 1 May 2018, In : Current Opinion in Colloid and Interface Science. 35, p. 26-35 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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14 Citations (Scopus)
76 Downloads (Pure)

Self-assembly and stabilization of hybrid cowpea chlorotic mottle virus particles under nearly physiological conditions

Timmermans, S. B. P. E., Vervoort, D. F. M., Schoonen, L., Nolte, R. J. M. & van Hest, J. C. M., 16 Nov 2018, In : Chemistry - An Asian Journal. 13, 22, p. 3518-3525 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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2 Citations (Scopus)
18 Downloads (Pure)

Self-assembly modulation of π-conjugated architectures in water

Schill, J., 12 Nov 2018, Eindhoven: Technische Universiteit Eindhoven. 156 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

7 Downloads (Pure)

Self-healing biomaterials: from molecular concepts to clinical applications

Diba, M., Spaans, S., Ning, K., Ippel, B. D., Yang, F., Loomans, B., Dankers, P. Y. W. & Leeuwenburgh, S. C. G., 7 Sep 2018, In : Advanced Materials Interfaces. 5, 17, 21 p., 1800118.

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)
2 Downloads (Pure)

Severe retinopathy of prematurity is associated with reduced cerebellar and brainstem volumes at term and neurodevelopmental deficits at 2 years

Drost, F. J., Keunen, K., Moeskops, P., Claessens, N. H. P., van Kalken, F., Išgum, I., Voskuil-Kerkhof, E. S. M., Groenendaal, F., de Vries, L. S., Benders, M. J. N. L. & Termote, J. U. M., 1 Apr 2018, In : Pediatric Research. 83, 4, p. 818–824 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Shear stress induces expression, intracellular reorganization and enhanced Notch activation potential of Jagged1

Driessen, R. C. H., Stassen, O. M. J. A., Sjöqvist, M., Suarez Rodriguez, F., Grolleman, J., Bouten, C. V. C. & Sahlgren, C. M., 1 Nov 2018, In : Integrative Biology. 10, 11, p. 719-726 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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2 Citations (Scopus)
31 Downloads (Pure)

Sheep-specific immunohistochemical panel for the evaluation of regenerative and inflammatory processes in tissue-engineered heart valves

Dekker, S., van Geemen, D., van den Bogaerdt, A. J., Driessen-Mol, A., Aikawa, E. & Smits, A. I. P. M., 15 Aug 2018, In : Frontiers in Cardiovascular Medicine. 5, 19 p., 105.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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4 Citations (Scopus)
36 Downloads (Pure)

Sialic acid blockade suppresses tumor growth by enhancing t-cell–mediated tumor immunity

Bull, C., Boltje, T. J., Balneger, N., Weischer, S. M., Wassink, M., van Gemst, J. J., Bloemendal, V., Boon, L., van der Vlag, J., Heise, T., den Bronk, M. & Adema, G. J., 1 Jul 2018, In : Cancer Research. 78, 13, p. 3574-3588 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
25 Citations (Scopus)

Sigma factor-mediated tuning of bacterial cell-free synthetic genetic oscillators

Yelleswarapu, M., van der Linden, A. J., Pieters, P. A., Dubuc, E., de Greef, T. F. A. & Huck, W. T. S., 8 Nov 2018, In : ACS Synthetic Biology. 7, 12, p. 2879-2887 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Citations (Scopus)
56 Downloads (Pure)

Simultaneous arteriole and venule segmentation with domain-specific loss function on a new public database

Xu, X., Wang, R., Lv, P., Gao, B., Li, C., Tian, Z., Tan, T. & Xu, F., 1 Jul 2018, In : Biomedical Optics Express. 9, 7, p. 3153-3166 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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3 Citations (Scopus)
36 Downloads (Pure)

Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells

Wimmers, F., Subedi, N., van Buuringen, N., Heister, D., Vivié, J., Beeren-Reinieren, I., Woestenenk, R., Dolstra, H., Piruska, A., Jacobs, J. F. M., van Oudenaarden, A., Figdor, C. G., Huck, W. T. S., de Vries, I. J. M. & Tel, J., 1 Dec 2018, In : Nature Communications. 9, 1, 12 p., 3317.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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22 Citations (Scopus)
72 Downloads (Pure)

Single dose of empagliflozin increases in vivo cardiac energy status in diabetic db/db mice

Abdurrachim, D., Manders, E., Nicolay, K., Mayoux, E. & Prompers, J. J., 1 Dec 2018, In : Cardiovascular Research. 114, 14, p. 1843-1844 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Skeletal muscle characteristics and exercise intolerance in chronic heart failure

Niemeijer, V. M., 11 Jan 2018, Eindhoven: Technische Universiteit Eindhoven. 247 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
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744 Downloads (Pure)

Skeletal muscle fiber characteristics in patients with chronic heart failure: Impact of disease severity and relation with muscle oxygenation during exercise

Niemeijer, V. M., Snijders, T., Verdijk, L. B., Van Kranenburg, J., Groen, B. B. L., Holwerda, A. M., Spee, R. F., Wijn, P. F. F., Van Loon, L. J. C. & Kemps, H. M. C., 1 Oct 2018, In : Journal of Applied Physiology. 125, 4, p. 1266-1276 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Spatially resolved sensitivity of single-particle plasmon sensors

Beuwer, M. A., van Hoof, B. & Zijlstra, P., 1 Mar 2018, In : Journal of Physical Chemistry C. 122, 8, p. 4615-4621 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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8 Citations (Scopus)
81 Downloads (Pure)

Spatial patterning of the Notch ligand Dll4 controls endothelial sprouting in vitro

Tiemeijer, L. A., Frimat, J. P., Stassen, O. M. J. A., Bouten, C. V. C. & Sahlgren, C. M., 1 Dec 2018, In : Scientific Reports. 8, 1, 10 p., 6392.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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3 Citations (Scopus)
54 Downloads (Pure)

Statins promote cardiac infarct healing by modulating endothelial barrier function revealed by contrast-enhanced magnetic resonance imaging

Leenders, G. J., Smeets, M. B., Van Den Boomen, M., Berben, M., Nabben, M., Van Strijp, D., Strijkers, G. J., Prompers, J. J., Arslan, F., Nicolay, K. & Vandoorne, K., 1 Jan 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 1, p. 186-194 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Strain mediated enzymatic degradation of arterial tissue: Insights into the role of the non-collagenous tissue matrix and collagen crimp

Gaul, R. T., Nolan, D. R., Ristori, T., Bouten, C. V. C., Loerakker, S. & Lally, C., 1 Sep 2018, In : Acta Biomaterialia. 77, p. 301-310 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
1 Downloads (Pure)

Strain-stiffening in dynamic supramolecular fiber networks

Fernández-Castaño Romera, M., Lou, X., Schill, J., ter Huurne, G., Fransen, P. P. K. H., Voets, I. K., Storm, C. & Sijbesma, R. P., 19 Dec 2018, In : Journal of the American Chemical Society. 140, 50, p. 17547-17555 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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4 Citations (Scopus)
67 Downloads (Pure)

Structural characterization of 14-3-3ζ in complex with the human Son of sevenless homolog 1 (SOS1)

Ballone, A., Centorrino, F., Wolter, M. & Ottmann, C., 1 Jun 2018, In : Journal of Structural Biology. 202, 3, p. 210-215 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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5 Citations (Scopus)
32 Downloads (Pure)

Sumoylation of Notch1 represses its target gene expression during cell stress

Antila, C. J. M., Rraklli, V., Blomster, H. A., Dahlström, K. M., Salminen, T. A., Holmberg, J., Sistonen, L. & Sahlgren, C. M., 1 Mar 2018, In : Cell Death and Differentiation. 25, 3, p. 600-615 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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4 Citations (Scopus)
60 Downloads (Pure)

Supramolecular block copolymers under thermodynamic control

Adelizzi, B., Aloi, A., Markvoort, A. J., ten Eikelder, H. M. M., Voets, I. K., Palmans, A. R. A. & Meijer, E. W., 13 Jun 2018, In : Journal of the American Chemical Society. 140, 23, p. 7168-7175 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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35 Citations (Scopus)
58 Downloads (Pure)

Supramolecular control over recognition of proteins and cells

van Dun, S., 19 Nov 2018, Eindhoven: Technische Universiteit Eindhoven. 121 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

4 Downloads (Pure)

Supramolecular copolymerization as a strategy to control the stability of self-assembled nanofibers

Thota, B. N. S., Lou, X., Bochicchio, D., Paffen, T. F. E., Lafleur, R. P. M., van Dongen, J. L. J., Ehrmann, S., Haag, R., Pavan, G. M., Palmans, A. R. A. & Meijer, E. W., 4 Jun 2018, In : Angewandte Chemie - International Edition. 57, 23, p. 6843-6847 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
2 Downloads (Pure)

Supramolecular drug delivery systems: molecular engineering of carrier affinity

Bakker, M. H., 30 Jan 2018, Eindhoven: Technische Universiteit Eindhoven. 144 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
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1176 Downloads (Pure)

Switching from infliximab innovator to biosimilar in patients with inflammatory bowel disease: A 12-month multicentre observational prospective cohort study

Schmitz, E. M. H., Boekema, P. J., Straathof, J. W. A., van Renswouw, D. C., Brunsveld, L., Scharnhorst, V., van de Poll, M. E. C., Broeren, M. A. C. & Derijks, L. J. J., 1 Feb 2018, In : Alimentary Pharmacology and Therapeutics. 47, 3, p. 356-363

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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35 Citations (Scopus)
89 Downloads (Pure)
Open Access
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9 Citations (Scopus)
142 Downloads (Pure)

Synthetic immune niches for cancer immunotherapy

Weiden, J., Tel, J. & Figdor, C. G., 1 Mar 2018, In : Nature Reviews Immunology. 18, 3, p. 212-219 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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47 Citations (Scopus)
414 Downloads (Pure)

Systems biology of Metabolic Syndrome development and treatment

Rozendaal, Y. J. W., 21 Dec 2018, Eindhoven: Technische Universiteit Eindhoven. 138 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
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354 Downloads (Pure)

Targeting somatostatin receptors by functionalized mesoporous silica nanoparticles-are we striking home?

Paramonov, V. M., Desai, D., Kettiger, H., Mamaeva, V., Rosenholm, J. M., Sahlgren, C. & Rivero-Müller, A., Jan 2018, In : Nanotheranostics. 2, 4, p. 320-346 27 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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10 Downloads (Pure)

Target of rapamycin FATC domain as a general membrane anchor: the FKBP-12 like domain of FKBP38 as a case study

De Cicco, M., Milroy, L. G. & Dames, S. A., 1 Feb 2018, In : Protein Science. 27, 2, p. 546-560 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Temperature-induced collapse of elastin-like peptides studied by 2DIR spectroscopy

Selig, O., da Cunha, A. M. D. C. V., van Eldijk, M. B., van Hest, J. C. M., Jansen, T. L. C., Bakker, H. J. & Rezus, Y. L. A., 1 Aug 2018, In : Journal of Physical Chemistry B. 122, 34, p. 8243-8254 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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3 Citations (Scopus)
35 Downloads (Pure)

Template matching via densities on the roto-translation group

Bekkers, E., Loog, M., Romeny, B. T. H. & Duits, R., 2018, In : IEEE Transactions on Pattern Analysis and Machine Intelligence. 40, 2, p. 452-466 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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4 Citations (Scopus)
69 Downloads (Pure)

The association between diabetes status, HbA1c, diabetes duration, microvascular disease, and bone quality of the distal radius and tibia as measured with high-resolution peripheral quantitative computed tomographyThe Maastricht Study

de Waard, E. A. C., de Jong, J. J. A., Koster, A., Savelberg, H. H. C. M., van Geel, T. A., Houben, A. J. H. M., Schram, M. T., Dagnelie, P. C., van der Kallen, C. J., Sep, S. J. S., Stehouwer, C. D. A., Schaper, N. C., Berendschot, T. T. J. M., Schouten, J. S. A. G., Geusens, P. P. M. M. & van den Bergh, J. P. W., Dec 2018, In : Osteoporosis International. 29, 12, p. 2725-2738 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Citations (Scopus)
27 Downloads (Pure)

The Clareon intraocular lens: first clinical experiences

Bauer, N. J. C., Veldhuizen, C. A., Berendschot, T. T. J. M. & Nuijts, R. M. M. A., Mar 2018, In : Acta Ophthalmologica. 96, p. 34-34

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
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83 Downloads (Pure)