Department of Biomedical Engineering

Research Output 1962 2020

2020
1 Downloads (Pure)

29th annual conference of the European Society for Biomaterials

Habibovic, P., Hofmann, S. & van den Beucken, J., 1 Jan 2020, In : Biomaterials Science. 8, 1, p. 16-17 2 p.

Research output: Contribution to journalEditorialAcademic

Biocompatible Materials
Biomaterials
Scaffolds
Polymers
Tissue

Alarmeringsoplossing voor het Prinses Maxima Centrum

van Vuuren, W., 6 Feb 2020, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven.

Research output: ThesisPd Eng Thesis

2 Downloads (Pure)

A metamodeling approach for instant severity assessment and uncertainty quantification of iliac artery stenoses

Heinen, S. G. H., Gashi, K., van den Heuvel, D. A. F., de Vries, J. P. P. M., van de Vosse, F. N., Delhaas, T. & Huberts, W., 1 Jan 2020, In : Journal of Biomechanical Engineering. 142, 1, 8 p., 011010.

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Uncertainty
Pathologic Constriction
Pressure drop
Pressure

Engineering interactive artificial cells

Buddingh, B., 20 Jan 2020, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven. 178 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

7 Downloads (Pure)

Fiber scaffold patterning for mending hearts: 3D organization bringing the next step

Kristen, M., Ainsworth, M. J., Chirico, N., van der Ven, C. F. T., Doevendans, P. A., Sluijter, J. P. G., Malda, J., van Mil, A. & Castilho, M., Jan 2020, In : Advanced Healthcare Materials. 9, 1, 1900775.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Scaffolds
Organizations
Technology
Fibers
Tissue Engineering
1 Downloads (Pure)

Fluid shear stress in endothelial Notch signaling

Driessen, R. C. H., 11 Feb 2020, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven. 156 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
File
6 Downloads (Pure)
Open Access
File
Macrophages
Hemodynamics
Biocompatible Materials
Tissue engineering
Biomaterials

Hybrid bio/supra-molecular polymers as programmable nano-architectures

Magdalena Estirado, E., 13 Jan 2020, Eindhoven: Technische Universiteit Eindhoven. 193 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Knie: nieuwe inzichten behandeling kruisband- en meniscusletsels bij kinderen

Translated title of the contribution: Knee: new insights in treatment of anterior cruciate ligament and meniscus injuries in childrenJanssen, R. P. A., 2020.

Research output: Contribution to conferencePaperAcademic

1 Downloads (Pure)

Layer-specific cell differentiation in bi-layered vascular grafts under flow perfusion

Pennings, I., van Haaften, E. E., Juengst, T., Bulsink, J. A., Rosenberg, A. J. W. P., Groll, J., Bouten, C. V. C., Kurniawan, N. A., Smits, A. I. P. M. & Gawlitta, D., Jan 2020, In : Biofabrication. 12, 1, 13 p., 015009.

Research output: Contribution to journalArticleAcademicpeer-review

Grafts
Blood Vessels
Cell Differentiation
Perfusion
Transplants
6 Downloads (Pure)

Ligand-based design of allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists

Meijer, F. A., Doveston, R. G., de Vries, R. M. J. M., Vos, G. M., Vos, A. A. A., Leysen, S., Scheepstra, M., Ottmann, C., Milroy, L-G. & Brunsveld, L., 9 Jan 2020, In : Journal of Medicinal Chemistry. 63, 1, p. 241-259 19 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Retinoic Acid Receptors
Isoxazoles
Cytoplasmic and Nuclear Receptors
Ligands
Interleukin-17

Mechanics of Soft Tissue Damage: a collaboration in seven courses

Bader, D. L., 4 Jan 2020, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven.

Research output: Book/ReportBookAcademic

Microvascular dysfunction is associated with worse cognitive performance the Maastricht study

Rensma, S. P., van Sloten, T. T., Houben, A. J. H. M., Koehler, S., van Boxtel, M. P. J., Berendschot, T. T. J. M., Jansen, J. F. A., Verhey, F. R. J., Kroon, A. A., Koster, A., Backes, W. H., Schaper, N., Dinant, G-J., Schalkwijk, C. G., Henry, R. M. A., Wolfs, E. M. L., van Heumen, M. J. A., Schram, M. T. & Stehouwer, C. D. A., Jan 2020, In : Hypertension. 75, 1, p. 237-245 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Modular lipid nanoparticle platform technology for siRNA and lipophilic prodrug delivery

van der Meel, R., Chen, S., Zaifman, J., Kulkarni, J. A., Zhang, X. R. S., Tam, Y. K., Bally, M. B., Schiffelers, R. M., Ciufolini, M. A., Cullis, P. R. & Tam, Y. Y. C., 16 Jan 2020

Research output: Other contributionAcademic

Open Access
Prodrugs
Nanoparticles
Small Interfering RNA
Technology
Lipids
3 Downloads (Pure)

Multi-component supramolecular fibers with elastomeric properties and controlled drug release

Putti, M., Mes, T., Huang, J., Bosman, A. W. & Dankers, P. Y. W., Jan 2020, In : Biomaterials Science. 8, 1, p. 163-173 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pyrimidinones
Polyethylene glycols
Fibers
Pharmaceutical Preparations
Electrospinning

Ontwerp en inrichting van een kwaliteitsborgingssysteem medische hulpmiddelen

Nijenhuis, S., 11 Jan 2020, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven.

Research output: ThesisPd Eng Thesis

8 Downloads (Pure)

Peptidic antifreeze materials: from design to potential applications

Suris Valls, R., 16 Jan 2020, Eindhoven: Technische Universiteit Eindhoven. 138 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
File

Peroxiredoxin proteins as building blocks for nanotechnology

Conroy, F. & Yewdall, A., 2020, Protein Nanotechnology. Gerard, J. & Domigan, L. (eds.). Humana: Springer, p. 39-54 16 p. (Methods in Molecular Biology; vol. 2073).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Peroxiredoxins
Nanotechnology
Proteins
Transmission Electron Microscopy
Centrifugation

Prevalence and predictability of kinesiophobia after anterior cruciate ligament reconstruction

Theunissen, W. W. E. S., van der Steen, M. C., Liu, W. Y. & Janssen, R. P. A., 2020, (Accepted/In press).

Research output: Contribution to conferencePosterAcademic

4 Downloads (Pure)

Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome

Rosier, B., Markvoort, B., Gumi Audenis, B., Roodhuizen, J., den Hamer, A., Brunsveld, L. & de Greef, T. F. A., 6 Jan 2020, In : Nature Catalysis. 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Apoptosomes
Caspase 9
DNA
Protein Engineering
Multiprotein Complexes
1 Downloads (Pure)

Reaching the tumour: nanoscopy study of nanoparticles in the biological environment

Feiner Gracia, N., 23 Jan 2020, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven. 191 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
File

Reproducibility assessment of ultrasound-based aortic stiffness quantification and verification using Bi-axial tensile testing

van Disseldorp, E. M. J., van den Hoven, M. H. M. H., van de Vosse, F. N., van Sambeek, M. R. H. M. & Lopata, R. G. P., Mar 2020, In : Journal of the Mechanical Behavior of Biomedical Materials. 103, 103571.

Research output: Contribution to journalArticleAcademicpeer-review

Tensile testing
Ultrasonics
Stiffness
Tissue
Surgery

Return to sport criteria for children after anterior cruciate ligament injury or reconstruction – a scoping review

Dietvorst, M., Brzoskowski, M. H., van der Steen, M. C., Delvaux, E., Janssen, R. P. A. & van Melick, N., 2020, (Accepted/In press).

Research output: Contribution to conferencePosterAcademic

1 Downloads (Pure)

Supervised deformable image registration using deep neural networks

Eppenhof, K. A. J., 11 Feb 2020, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven. 119 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)

Open Access
File

The influence of expectation modification in knee arthroplasty on satisfaction of patients a randomized controlled trial: the EKSPECT study

Tolk, J. J., Janssen, R. P. A., Haanstra, T. M., Bierma-Zeinstra, S. M. A. & Reijman, M., 2020, (Accepted/In press).

Research output: Contribution to conferencePaperAcademic

Ultrasound based wall stress analysis of abdominal aortic aneurysms using multiperspective imaging

van Disseldorp, E. M. J., van Dronkelaar, J. J., Pluim, J. P. W., van de Vosse, F. N., van Sambeek, M. R. H. M. & Lopata, R. G. P., 1 Jan 2020, In : European Journal of Vascular and Endovascular Surgery. 59, 1, p. 81-91 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Abdominal Aortic Aneurysm
Tomography
Aneurysm
Rupture
Magnetic Resonance Imaging
2019

Accelerating implant RF safety assessment using a low-rank inverse update method

Stijnman, P. R. S., Tokaya, J. P., van Gemert, J., Luijten, P. R., Pluim, J. P. W., Brink, W. M., Remis, R. F., van den Berg, C. A. T. & Raaijmakers, A. J. E., 30 Sep 2019, In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Radio
Safety
Magnetic Fields
Heating
Libraries

A comparative study of geometry-based methods and intra-arterial pressure measurements to assess the hemodynamic significance of equivocal iliac artery stenoses

Heinen, S. G. H., Huberts, W., van den Heuvel, D. A. F., van de Vosse, F. N., de Vries, J. P. P. M. & Delhaas, T., 1 Apr 2019, In : Vascular. 27, 2, p. 119-127 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Arterial Pressure
Pathologic Constriction
Hemodynamics
Blood Vessels
1 Downloads (Pure)

A computational approach on sensitivity of left ventricular wall strains to geometry

Barbarotta, L. & Bovendeerd, P., 2019, Functional Imaging and Modeling of the Heart - 10th International Conference, FIMH 2019, Proceedings. Coudière, Y., Ozenne, V., Vigmond, E. & Zemzemi, N. (eds.). Cham: Springer Nature Switzerland AG, p. 240-248 9 p. (Lecture Notes in Computer Science ; vol. 11504).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Mode Shape
Atlas
Finite Element Model
Principal Component Analysis
Mechanics
2 Downloads (Pure)

A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data

O'Donovan, S. D., Lenz, M., Vink, R. G., Roumans, N. J. T., de Kok, T. M. C. M., Mariman, E. C. M., Peeters, R. L. M., van Riel, N. A. W., van Baak, M. A. & Arts, I. C. W., Oct 2019, In : PLoS Computational Biology. 15, 10, 23 p., e1007400.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Lipid Metabolism
Radioactive tracers
isotope labeling
Isotopes
lipid metabolism
11 Downloads (Pure)

A computational model to predict cell traction-mediated prestretch in the mitral valve

van Kelle, M. A. J., Rausch, M. K., Kuhl, E. & Loerakker, S., 18 Nov 2019, In : Computer Methods in Biomechanics and Biomedical Engineering. 22, 15, p. 1174-1185 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tissue
Actins
Structural properties
Anisotropy
Fibers
1 Citation (Scopus)
7 Downloads (Pure)

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation

Korkmaz, G., Manber, Z., Lopes, R., Prekovic, S., Schuurman, K., Kim, Y., Teunissen, H., Flach, K., Wit, E. D., Galli, G. G., Zwart, W., Elkon, R. & Agami, R., 10 Oct 2019, In : Nucleic Acids Research. 47, 18, p. 9557-9572 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Estrogen Receptors
Cell Proliferation
Breast Neoplasms
Chromatin
1 Citation (Scopus)
12 Downloads (Pure)

Adaptive polymeric assemblies for applications in biomimicry and nanomedicine

Altay, Y., Che, H., Cao, S., Abdelmohsen, L. & van Hest, J., 11 Nov 2019, In : Biomacromolecules. 20, 11, p. 4053-4064 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Medical nanotechnology
Nanostructured materials
Self assembly
Intelligent networks
Complex networks
1 Citation (Scopus)
32 Downloads (Pure)

Adaptive polymersome nanoreactors

Che, H. & van Hest, J. C. M., 1 Sep 2019, In : ChemNanoMat. 5, 9, p. 1092-1109 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoreactors
Medical nanotechnology
Adaptive systems
5 Downloads (Pure)

A deep learning method for image-based subject-specific local SAR assessment

Meliadò, E. F., Raaijmakers, A. J. E., Sbrizzi, A., Steensma, B. R., Maspero, M., Savenije, M. H. F., Luijten, P. R. & van den Berg, C. A. T., 4 Sep 2019, In : Magnetic Resonance in Medicine. 83, 2, p. 695-711 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Learning
Computer Simulation
Safety
Uncertainty
Prostate

Adherence to dabigatran etexilate in atrial fibrillation patients intended to undergo electrical cardioversion

Comuth, W. J., de Maat, M. P. M., van de Kerkhof, D., Malczynski, J., Husted, S., Kristensen, S. D. & Münster, A. M. B., 1 Apr 2019, In : European Heart Journal - Cardiovascular Pharmacotherapy. 5, 2, p. 91-99 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Electric Countershock
Atrial Fibrillation
Medication Adherence
Therapeutics
Dabigatran
2 Downloads (Pure)

A geometry-based model for non-invasive estimation of pressure gradients over iliac artery stenoses

Heinen, S. G. H., van den Heuvel, D. A. F., de Vries, J. P. P. M., van de Vosse, F. N., Delhaas, T. & Huberts, W., 19 Jul 2019, In : Journal of Biomechanics. 92, p. 67-75 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Pressure gradient
Pathologic Constriction
Angiography
Pressure
5 Downloads (Pure)

Alendronate-functionalized poly(2-oxazoline)s with tunable affinity for calcium cations

Sánchez-Fernández, M. J., Immers, M. R., Félix Lanao, R. P., Yang, F., Bender, J. C. M. E., Mecinović, J., Leeuwenburgh, S. C. G. & van Hest, J. C. M., 12 Aug 2019, In : Biomacromolecules. 20, 8, p. 2913-2921 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Alendronate
Cations
Calcium
Polymers
Positive ions
5 Citations (Scopus)
109 Downloads (Pure)

Allosteric small molecule modulators of nuclear receptors

Meijer, F. A., Leijten-van de Gevel, I. A., de Vries, R. M. J. M. & Brunsveld, L., 5 Apr 2019, In : Molecular and Cellular Endocrinology. 485, p. 20-34 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Cytoplasmic and Nuclear Receptors
Allosteric Site
Ligands
Drug Discovery
Pathology
26 Downloads (Pure)
Open Access
File
Intravenous Administration
Theoretical Models
Clinical Decision Support Systems
Mathematical models
Fluids

A microfluidic oxygen gradient device to assess EMT state and migrational responses of cancer cells

Sleeboom, J., van der Doelen, K., Kruyt, F., Sahlgren, C. M. & den Toonder, J. M. J., Jul 2019.

Research output: Contribution to conferencePosterAcademic

2 Downloads (Pure)

A microfluidic oxygen gradient device to assess EMT state and migrational responses of cancer cells

Sleeboom, J., van der Doelen, K., Kruyt, F., Sahlgren, C. M. & den Toonder, J. M. J., Jun 2019.

Research output: Contribution to conferencePosterAcademic

File
1 Citation (Scopus)

AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins

Saline, M., Badertscher, L., Wolter, M., Lau, R., Gunnarsson, A., Jacso, T., Norris, T., Ottmann, C. & Snijder, A., 30 Aug 2019, In : Journal of Biological Chemistry. 294, 35, p. 13106-13116 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

14-3-3 Proteins
Phosphorylation
AMP-Activated Protein Kinases
Protein Kinases
Transcription Factors
33 Downloads (Pure)

A multicenter evaluation of a point of care CRP Test

Scharnhorst, V., Noordzij, P. G., Lutz, A., Graser, U., Püntener, D. & Alquézar-Arbé, A., 1 Sep 2019, In : Clinical Biochemistry. 71, Sept 2019, p. 38-45 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Point-of-Care Systems
C-Reactive Protein
Blood
Serum
Plasmas
71 Downloads (Pure)

A multilayer microfluidic platform for the conduction of prolonged cell-free gene expression

van der Linden, A., Pieters, P., Yelleswarapu, M., Swank, Z., Huck, W. T. S., Maerkl, S. & de Greef, T., 1 Oct 2019, In : Journal of Visualized Experiments (JoVE). 152, 14 p., e59655.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Lab-On-A-Chip Devices
Microfluidics
Transcription
Gene expression
Multilayers
6 Downloads (Pure)
Open Access
File
Tissue Scaffolds
Tissue Engineering
Scaffold
Microfluidics
Fluidics
3 Citations (Scopus)
7 Downloads (Pure)

Analysis of chemical exchange saturation transfer contributions from brain metabolites to the Z-spectra at various field strengths and pH

Khlebnikov, V., van der Kemp, W. J. M., Hoogduin, H., Klomp, D. W. J. & Prompers, J. J., 31 Jan 2019, In : Scientific Reports. 9, 1, 11 p., 1089.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
1 Downloads (Pure)

An aptamer-based new method for competitive fluorescence detection of exosomes

Yu, X., He, L., Pentok, M., Yang, H., Yang, Y., Li, Z., He, N., Deng, Y., Li, S., Liu, T., Chen, X. & Luo, H., 7 Sep 2019, In : Nanoscale. 11, 33, p. 15589-15595 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fluorescence
Biomarkers
Costs
Cells
Proteins
4 Downloads (Pure)

Androgen receptor genomics for patient stratification: from biomarker discovery to mechanisms

Stelloo, S., 1 Jul 2019, Eindhoven: Technische Universiteit Eindhoven. 291 p.

Research output: ThesisPhd Thesis 2 (Research NOT TU/e / Graduation TU/e)

1 Citation (Scopus)

A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitude

Gigante, A., Grad, J. N., Briels, J., Bartel, M., Hoffmann, D., Ottmann, C. & Schmuck, C., 4 Jan 2019, In : Chemical Communications. 55, 1, p. 111-114 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Neurodegenerative diseases
14-3-3 Proteins
Signal transduction
Ligands
Proteins