Department of Biomedical Engineering

Research Output 1962 2019

2019

A multilayer microfluidic platform for the conduction of prolonged cell-free gene expression

van der Linden, A., Pieters, P., Yelleswarapu, M., Swank, Z., Huck, W. T. S., Maerkl, S. & de Greef, T., 2019, (Accepted/In press) In : Journal of Visualized Experiments (JoVE).

Research output: Contribution to journalArticleAcademicpeer-review

File

A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitude

Gigante, A., Grad, J. N., Briels, J., Bartel, M., Hoffmann, D., Ottmann, C. & Schmuck, C., 1 Jan 2019, In : Chemical Communications. 55, 1, p. 111-114 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Neurodegenerative diseases
14-3-3 Proteins
Signal transduction
Ligands
Proteins

Approximation of a pipeline of unsupervised retina image analysis methods with a CNN

Heslinga, F., Pluim, J., Dasht Bozorg, B., Berendschot, T., Houben, B., Henry, R. M. A. & Veta, M., Feb 2019, (Accepted/In press) Image Processing. Bellingham: SPIE, 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Biomarkers
Image analysis
Pipelines
Neural networks
Chemical activation

A value proposition for trough level-based anti-TNFα drug dosing

Scharnhorst, V., Schmitz, E. M. H., van de Kerkhof, D., Derijks, L. J. J. & Broeren, M. A. C., 1 Feb 2019, In : Clinica Chimica Acta. 489, p. 89-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Monitoring
Pharmaceutical Preparations
Cost-Benefit Analysis
Therapeutics
Critical Pathways

Biomorphic engineering of multifunctional polylactide stomatocytes toward therapeutic nano-red blood cells

Shao, J., Pijpers, I. A. B., Cao, S., Williams, D. S., Yan, X., Li, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 1 Jan 2019, (Accepted/In press) In : Advanced Science.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
erythrocytes
Blood
Erythrocytes
Cells
engineering

Carbon nanotube reinforced supramolecular hydrogels for bioapplications

Mihajlovic, M., Mihajlovic, M., Dankers, P. Y. W., Masereeuw, R. & Sijbesma, R. P., 1 Jan 2019, In : Macromolecular Bioscience. 19, 12 p., 1800173

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Carbon Nanotubes
Hydrogels
Nanocomposites
Carbon nanotubes
Hydrogel
1 Citations

Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study

Samelson, E. J., Broe, K. E., Xu, H., Yang, L., Boyd, S., Biver, E., Szulc, P., Adachi, J., Amin, S., Atkinson, E., Berger, C., Burt, L., Chapurlat, R., Chevalley, T., Ferrari, S., Goltzman, D., Hanley, D. A., Hannan, M. T., Khosla, S., Liu, C-T. & 13 othersLorentzon, M., Mellstrom, D., Merle, B., Nethander, M., Rizzoli, R., Sornay-Rendu, E., van Rietbergen, B., Sundh, D., Wong, A. K. O., Ohlsson, C., Demissie, S., Kiel, D. P. & Bouxsein, M. L., 1 Jan 2019, In : Lancet Diabetes & Endocrinology. 7, 1, p. 34-43 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bone Density
Prospective Studies
Bone and Bones
Femur Neck
Tibia

Counterion dependent mechanisms of DNA origami nanostructure stabilization revealed by atomistic molecular simulation

Roodhuizen, J., Hendrikx, P. J. T. M., Hilbers, P. A. J., de Greef, T. & Markvoort, B., 2019, (Accepted/In press) In : ACS Nano.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citations

Development of morphologically discrete PEG-PDLLA nanotubes for precision nanomedicine

Wauters, A. C., Pijpers, I. A. B., Mason, A. F., Williams, D. S., Tel, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 1 Jan 2019, In : Biomacromolecules. 20, 1, p. 177-183

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Medical nanotechnology
Nanotubes
Polyethylene glycols
Particle interactions
Nanostructures

DNA-based communication in populations of synthetic protocells

Joesaar, A. H., Yang, S., Bögels, B. W. A., van der Linden, A. J., Pieters, P. A., Kumar, P., Dachau, N., Phillips, A., Mann, S. & de Greef, T. F. A., 2019, (Accepted/In press) In : Nature Nanotechnology.

Research output: Contribution to journalArticleAcademicpeer-review

Engineered cardiac microenvironments based on supramolecular biomaterials

Spaans, S., 13 Mar 2019, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven. 175 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Environmental stimuli for controlled bone tissue engineering applications

Melke, J., 14 Mar 2019, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

1 Citations

Epileptic seizure detection in EEG signals using sparse multiscale radial basis function networks and the Fisher vector approach

Li, Y., Cui, W. G., Huang, H., Guo, Y. Z., Li, K. & Tan, T., 15 Jan 2019, In : Knowledge-Based Systems. 164, p. 96-106

Research output: Contribution to journalArticleAcademicpeer-review

Radial basis function networks
Electroencephalography
Statistical tests
Model structures
Particle swarm optimization (PSO)

Evaluating aetiological processes for monitoring and detection of deep tissue injury

Traa, W. A., 19 Feb 2019, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven. 140 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Open Access
File

Fourier transform on the homogeneous space of 3D positions and orientations for exact solutions to linear PDEs

Duits, R., Bekkers, E. J. & Mashtakov, A., 8 Jan 2019, In : Entropy. 21, 1, 38 p., 38

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
pulse detonation engines
quotients
rigid structures
robotics
image analysis

Identification of topographical architectures supporting the phenotype of rat tenocytes

Vermeulen, S., Vasilevich, A., Tsiapalis, D., Roumans, N., Vroemen, P., Beijer, N. R. M., Dede Eren, A., Zeugolis, D. & de Boer, J., 1 Jan 2019, In : Acta Biomaterialia. 83, p. 277-290

Research output: Contribution to journalArticleAcademicpeer-review

Topography
Rats
Tendons
Phenotype
Screening

Maternal hemoglobin level and its relation to fetal distress, mode of delivery, and short-term neonatal outcome: a retrospective cohort study

Bullens, L. M., Smith, J. S., Truijens, S. E. M., van der Hout-van der Jagt, M. B., van Runnard Heimel, P. J. & Oei, S. G., 31 Jan 2019, In : Journal of Maternal-Fetal and Neonatal Medicine. p. 1-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fetal Distress
Hemoglobins
Cohort Studies
Retrospective Studies
Mothers

Mechanical analysis of aortic aneurysms using 3D ultrasound : towards patient-specific risk assessment

van Disseldorp, E. M. J., 10 Jan 2019, Eindhoven: Technische Universiteit Eindhoven. 178 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Open Access
File
Risk assessment
Ultrasonics

Mechanically driven adaptation in engineered cardiovascular tissues

van Kelle, A. J., 31 Jan 2019, Eindhoven: Technische Universiteit Eindhoven. 134 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Heart Valves
Blood Vessels
Open Access
File
Micellization
Surface-Active Agents
self consistent fields
Surface active agents
Salts

Mimicking Active Biopolymer Networks with a Synthetic Hydrogel

Fernández-Castano Romera, M., Göstl, R., Shaikh, H., Ter Huurne, G., Schill, J., Voets, I. K., Storm, C. & Sijbesma, R. P., 6 Feb 2019, In : Journal of the American Chemical Society. 141, 5, p. 1989-1997 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Molecular repolarisation of tumour-associated macrophages

van Dalen, F. J., van Stevendaal, M. H. M. E., Fennemann, F. L., Verdoes, M. & Ilina, O., 1 Jan 2019, In : Molecules. 24, 1, 25 p., 9

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
macrophages
Macrophages
Tumors
tumors
Neoplasms

Nanoimmunotherapy to treat ischaemic heart disease

Duivenvoorden, R., Senders, M. L., van Leent, M. M. T., Pérez-Medina, C., Nahrendorf, M., Fayad, Z. A. & Mulder, W. J. M., 2019, In : Nature Reviews. Cardiology. 16, p. 21-32

Research output: Contribution to journalArticleAcademicpeer-review

Myocardial Ischemia
Atherosclerosis
Inflammation
Lipids
Recurrence

On the relationship between dynamic contrast-enhanced ultrasound parameters and the underlying vascular architecture extracted from acoustic angiography

Panfilova, A., Shelton, S. E., Caresio, C., van Sloun, R. J. G., Molinari, F., Wijkstra, H., Dayton, P. A. & Mischi, M., Feb 2019, In : Ultrasound in Medicine and Biology. 45, 2, p. 539-548

Research output: Contribution to journalArticleAcademicpeer-review

angiography
Acoustics
Blood Vessels
Angiography
Perfusion

Ontwerp van een kwaliteitssysteem voor de afdeling medische technologie

Plieger, M., 8 Jan 2019, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven.

Research output: ThesisPd Eng ThesisOther research output

Prospective follow-Up of cortical interruptions, bone density, and micro-structure detected on HR-pQCT: A study in patients with rheumatoid arthritis and healthy subjects

Peters, M., van den Bergh, J. P., Geusens, P., Scharmga, A., Loeffen, D., Weijers, R., van Rietbergen, B. & van Tubergen, A., 1 Feb 2019, In : Calcified Tissue International.

Research output: Contribution to journalArticleAcademicpeer-review

Bone Density
Antirheumatic Agents
Rheumatoid Arthritis
Healthy Volunteers
Tomography

Quantifying guest–host dynamics in supramolecular assemblies to analyze their robustness

Bastings, M. M. C., Hermans, T. M., Spiering, A. J. H., Kemps, E. W. L., Albertazzi, L., Kurisinkal, E. E. & Dankers, P. Y. W., 1 Jan 2019, In : Macromolecular Bioscience. 19, 1, 11 p., 1800296

Research output: Contribution to journalArticleAcademicpeer-review

Pyrimidinones
Fluorescence Recovery After Photobleaching
Photobleaching
Fluorescence Resonance Energy Transfer
Microfluidics

RegressionExplorer: Interactive exploration of logistic regression models with subgroup analysis

Dingen, D., van 't Veer, M., Houthuizen, P., Mestrom, E. H. J., Korsten, E. H. H. M., Bouwman, A. R. A. & van Wijk, J., 1 Jan 2019, In : IEEE Transactions on Visualization and Computer Graphics. 25, 1, p. 246-255 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Logistics

Robust non-rigid motion compensation of free-breathing myocardial perfusion MRI data

Scannell, C. M., Villa, A. D. M., Lee, J., Breeuwer, M. & Chiribiri, A., 1 Feb 2019, In : IEEE Transactions on Medical Imaging.

Research output: Contribution to journalArticleAcademicpeer-review

Motion compensation
Magnetic Resonance Angiography
Magnetic resonance
Compensation and Redress
Respiration
antifouling
Scaffolds
Adhesives
adhesives
casts

The dual-mode dipole: A new array element for 7T body imaging with reduced SAR

Solomakha, G., Leeuwen, C. V., Raaijmakers, A., Simovski, C., Popugaev, A., Abdeddaim, R., Melchakova, I. & Glybovski, S., 1 Feb 2019, In : Magnetic Resonance in Medicine. 81, 2, p. 1459-1469

Research output: Contribution to journalArticleAcademicpeer-review

Prostate
Volunteers
Open Access
File
Pathologic Constriction
Geometry
Hydrodynamics
Uncertainty
Dynamic models
2018
1 Citations

14-3-3: A case study in ppi modulation

Ballone, A., Centorrino, F. & Ottmann, C., 1 Jan 2018, In : Molecules. 23, 6, 14 p., 1386

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
14-3-3 Proteins
Modulation
proteins
modulation
Proteins
3 Citations
Open Access
File
Biomimetics
Microfluidics
Endothelial cells
Hemodynamics
Vascular Smooth Muscle

Accelerated 4D phase contrast MRI in skeletal muscle contraction

Mazzoli, V., Gottwald, L. M., Peper, E. S., Froeling, M., Coolen, B. F., Verdonschot, N., Sprengers, A. M., van Ooij, P., Strijkers, G. J. & Nederveen, A. J., 1 Nov 2018, In : Magnetic Resonance in Medicine. 80, 5, p. 1799-1811 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Muscle Contraction
Skeletal Muscle
Muscles
Volunteers
Leg
1 Citations

Accelerating DNA-based computing on a supramolecular polymer

Engelen, W., Wijnands, S. P. W. & Merkx, M., 1 Aug 2018, In : Journal of the American Chemical Society. 140, 30, p. 9758-9767 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polymers
DNA
Benzene
Networks (circuits)
Molecular Computers
3 Citations

Adaptation of a MR imaging protocol into a real-time clinical biometric ultrasound protocol for persons with spinal cord injury at risk for deep tissue injury: A reliability study

Swaine, J. M., Moe, A., Breidahl, W., Bader, D. L., Oomens, C. W. J., Lester, L., O'Loughlin, E., Santamaria, N. & Stacey, M. C., 1 Feb 2018, In : Journal of Tissue Viability. 27, 1, p. 2-9 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Spinal Cord Injuries
Tendons
Skin
Spinal Cord
Wounds and Injuries

Adaptive polymersome and micelle morphologies in anticancer nanomedicine: from design rationale to fabrication and proof-of-concept studies

Pijpers, I. A. B., Abdelmohsen, L. K. E. A., Xia, Y., Cao, S., Williams, D. S., Meng, F., van Hest, J. C. M. & Zhong, Z., 1 Dec 2018, In : Advanced Therapeutics. 1, 8, 14 p., 1800068

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Medical nanotechnology
Micelles
Nanoparticles
Fabrication
Drug delivery

A distance measure for heterogeneity using genome scale metabolic networks

Cabbia, A., Hilbers, P. A. J. & van Riel, N. A. W., 14 Oct 2018

Research output: Contribution to conferencePosterAcademic

Metabolic Networks and Pathways
Genome
Neoplasms
Organized Financing
European Union

A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

De Jong, E., Williams, D. S., Abdelmohsen, L. K. E. A., van Hest, J. C. M. & Zuhorn, I. S., 10 Nov 2018, In : Journal of Controlled Release. 289, p. 14-22 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Fluorescence Spectrometry
Blood-Brain Barrier
Nanoparticles
Transcytosis
Brain
2 Citations

Afivo: a framework for quadtree/octree AMR with shared-memory parallelization and geometric multigrid methods

Teunissen, J. & Ebert, U., 1 Dec 2018, In : Computer Physics Communications. 233, p. 156-166

Research output: Contribution to journalArticleAcademicpeer-review

multigrid methods
Data storage equipment
files
simulation
grids
3 Citations

AFM-detected apoptosis of hepatocellular carcinoma cells induced by American ginseng root water extract

Qu, Y., Wang, Z., Zhao, F., Liu, J., Zhang, W., Li, J., Song, Z. & Xu, H., 1 Jan 2018, In : Micron. 104, p. 1-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Panax
Hepatocellular Carcinoma
Apoptosis
Water
Elastic Modulus
Open Access
Biomarkers
Blood Vessels
Retina
Retinal Vessels
Pipelines
1 Citations

A liquid chromatography/mass spectrometry method for screening disulfide tethering fragments

Hallenbeck, K. K., Davies, J. L., Merron, C., Ogden, P., Sijbesma, E., Ottmann, C., Renslo, A. R., Wilson, C. & Arkin, M. R., 2018, In : SLAS Discovery. 23, 2, p. 183-192 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Liquid chromatography
Disulfides
Mass spectrometry
Screening
Pipelines
4 Citations

All-optical imaging of gold nanoparticle geometry using super-resolution microscopy

Taylor, A., Verhoef, R., Beuwer, M., Wang, Y. & Zijlstra, P., 1 Feb 2018, In : Journal of Physical Chemistry C. 122, 4, p. 2336-2342 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Gold
Microscopic examination
gold
Nanoparticles
microscopy

All-printed cell counting chambers with on-chip sample preparation for point-of-care CD4 counting

Wasserberg, D., Zhang, X., Breukers, C., Connell, B. J., Baeten, E., van den Blink, D., Solà Benet, È., Bloem, A. C., Nijhuis, M., Wensing, A. M. J., Terstappen, L. W. M. M. & Beck, M., 15 Oct 2018, In : Biosensors and Bioelectronics. 117, p. 659-668 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Point-of-Care Systems
Antibodies
Microfluidics
Tissue Donors
HIV
7 Citations

A microfluidics platform for combinatorial drug screening on cancer biopsies

Eduati, F., Utharala, R., Madhavan, D., Neumann, U. P., Longerich, T., Cramer, T., Saez-Rodriguez, J. & Merten, C. A., 22 Jun 2018, In : Nature Communications. 9, 1, 13 p., 2434

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Preclinical Drug Evaluations
Microfluidics
Biopsy
Drug Combinations
Tumors

A model of human skin under large amplitude oscillatory shear

Soetens, J. F. J., van Vijven, M., Bader, D. L., Peters, G. W. M. & Oomens, C. W. J., 1 Oct 2018, In : Journal of the Mechanical Behavior of Biomedical Materials. 86, p. 423-432 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Skin
Constitutive models
Shear thinning
Parameter estimation
Shear deformation
3 Citations

Amphiphilic poly(α)glutamate polymeric micelles for systemic administration of siRNA to tumors

Krivitsky, A., Polyak, D., Scomparin, A., Eliyahu, S., Ofek, P., Tiram, G., Kalinski, H., Avkin-Nachum, S., Feiner Gracia, N., Albertazzi, L. & Satchi-Fainaro, R., 1 Feb 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 2, p. 303-315 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Micelles
Small Interfering RNA
Tumors
Glutamic Acid
Bearings (structural)