Department of Biomedical Engineering

Research Output 1962 2019

2019

A comparative study of geometry-based methods and intra-arterial pressure measurements to assess the hemodynamic significance of equivocal iliac artery stenoses

Heinen, S. G. H., Huberts, W., van den Heuvel, D. A. F., van de Vosse, F. N., de Vries, J. P. P. M. & Delhaas, T., 1 Apr 2019, In : Vascular. 27, 2, p. 119-127 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Arterial Pressure
Pathologic Constriction
Hemodynamics
Blood Vessels

A computational approach on sensitivity of left ventricular wall strains to geometry

Barbarotta, L. & Bovendeerd, P., 2019, FIMH 2019: Functional Imaging and Modeling of the Heart . Coudière, Y., Ozenne, V., Vigmond, E. & Zemzemi, N. (eds.). Cham: Springer Nature Switzerland AG, p. 240-248 9 p. (Lecture Notes in Computer Science ; vol. 11504)

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Mode Shape
Atlas
Finite Element Model
Principal Component Analysis
Mechanics

Adaptive polymersome nanoreactors

Che, H. & van Hest, J. C. M., 27 May 2019, In : ChemNanoMat.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nanoreactors
Medical nanotechnology
Adaptive systems

Adherence to dabigatran etexilate in atrial fibrillation patients intended to undergo electrical cardioversion

Comuth, W. J., de Maat, M. P. M., van de Kerkhof, D., Malczynski, J., Husted, S., Kristensen, S. D. & Münster, A. M. B., 1 Apr 2019, In : European Heart Journal - Cardiovascular Pharmacotherapy. 5, 2, p. 91-99 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Electric Countershock
Atrial Fibrillation
Medication Adherence
Therapeutics
Dabigatran

A geometry-based model for non-invasive estimation of pressure gradients over iliac artery stenoses

Heinen, S. G. H., van den Heuvel, D. A. F., de Vries, J. P. P. M., van de Vosse, F. N., Delhaas, T. & Huberts, W., 19 Jul 2019, In : Journal of Biomechanics. 92, p. 67-75

Research output: Contribution to journalArticleAcademicpeer-review

Iliac Artery
Pressure gradient
Pathologic Constriction
Angiography
Pressure
2 Citations (Scopus)

Allosteric small molecule modulators of nuclear receptors

Meijer, F. A., Leijten-van de Gevel, I. A., de Vries, R. M. J. M. & Brunsveld, L., 1 Apr 2019, In : Molecular and Cellular Endocrinology. 485, p. 20-34 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cytoplasmic and Nuclear Receptors
Allosteric Site
Ligands
Drug Discovery
Pathology
Open Access
File
Intravenous Administration
Theoretical Models
Clinical Decision Support Systems
Mathematical models
Fluids

A multicenter evaluation of a point of care CRP Test

Scharnhorst, V., Noordzij, P. G., Lutz, A., Graser, U., Püntener, D. & Alquézar-Arbé, A., 21 Jun 2019, In : Clinical Biochemistry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Point-of-Care Systems
C-Reactive Protein
Blood
Serum
Plasmas

A multilayer microfluidic platform for the conduction of prolonged cell-free gene expression

van der Linden, A., Pieters, P., Yelleswarapu, M., Swank, Z., Huck, W. T. S., Maerkl, S. & de Greef, T., 2019, (Accepted/In press) In : Journal of Visualized Experiments (JoVE).

Research output: Contribution to journalArticleAcademicpeer-review

File
Lab-On-A-Chip Devices
Microfluidics
Transcription
Gene expression
Multilayers
Open Access
Tissue Scaffolds
Tissue Engineering
Scaffold
Microfluidics
Fluidics

Androgen receptor genomics for patient stratification: from biomarker discovery to mechanisms

Stelloo, S., 1 Jul 2019, Eindhoven: Technische Universiteit Eindhoven. 291 p.

Research output: ThesisPhd Thesis 2 (Research NOT TU/e / Graduation TU/e)Academic

A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitude

Gigante, A., Grad, J. N., Briels, J., Bartel, M., Hoffmann, D., Ottmann, C. & Schmuck, C., 1 Jan 2019, In : Chemical Communications. 55, 1, p. 111-114 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Neurodegenerative diseases
14-3-3 Proteins
Signal transduction
Ligands
Proteins

An improved growth guidance system for children with scoliosis: design of a screw guide and spacer

Gabriels, F., 11 Mar 2019, Eindhoven: Technische Universiteit Eindhoven. 59 p.

Research output: ThesisPd Eng ThesisAcademic

Child Guidance
Scoliosis
Mebendazole
Toes
Polyethylene
1 Citation (Scopus)

A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: Towards in situ tissue-engineered vascular accesses for haemodialysis

van Uden, S., Vanerio, N., Catto, V., Bonandrini, B., Tironi, M., Figliuzzi, M., Remuzzi, A., Kock, L., Redaelli, A. C. L., Greco, F. G. & Riboldi, S. A., 1 Mar 2019, In : Biomedical Materials. 14, 2, p. 025007 18 p., 025007

Research output: Contribution to journalArticleAcademicpeer-review

Fibroins
Polyurethanes
Silk
Grafts
Tissue

A pipette-tip based method for seeding cells to droplet microfluidic platforms

Sinha, N., Subedi, N., Wimmers, F., Soennichsen, M. & Tel, J., 11 Feb 2019, In : Journal of visualized experiments : JoVE. 144, 10 p., e57848

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cloud seeding
Microfluidics
Encapsulation
Poisson distribution
Poisson Distribution

Approximation of a pipeline of unsupervised retina image analysis methods with a CNN

Heslinga, F., Pluim, J., Dasht Bozorg, B., Berendschot, T., Houben, A. J. H. M., Henry, R. M. A. & Veta, M., 15 Mar 2019, Image Processing: SPIE Medical Imaging, 2019, San Diego, California, United States. Angelini, E. D. & Landman, B. A. (eds.). Bellingham: SPIE, 7 p. 109491N. (Proceedings of SPIE; vol. 10949)

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Biomarkers
Image analysis
Pipelines
Neural networks
Chemical activation
Hypothermia
Myocardial Infarction
Temperature
Myocardial Reperfusion
Myocardium

A protocol update of the fractional flow reserve versus angiography for multivessel evaluation (FAME) 3 trial: a comparison of fractional flow reserve–guided percutaneous coronary intervention and coronary artery bypass graft surgery in patients with multivessel coronary artery disease

Zimmermann, F. M., de Bruyne, B., Pijls, N. H. J., Desai, M., Oldroyd, K. G., Reardon, M. J., Wendler, O., Woo, J., Yeung, A. C. & Fearon, W. F., 1 Aug 2019, In : American Heart Journal. 214, p. 156-157 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

A revised modular approach to (–)-trans-Δ 8 -THC and derivatives through late-stage Suzuki–Miyaura cross-coupling reactions

Bloemendal, V. R. L. J., Sondag, D., Elferink, H., Boltje, T. J., van Hest, J. C. M. & Rutjes, F. P. J. T., 31 Mar 2019, In : European Journal of Organic Chemistry. 2019, 12, p. 2289-2296 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
thermohaline circulation
Dronabinol
cross coupling
Derivatives
Scaffolds

Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins

Maity, D., Gigante, A., Sánchez-Murcia, P. A., Sijbesma, E., Li, M., Bier, D., Mosel, S., Knauer, S., Ottmann, C. & Schmuck, C., 2 Apr 2019, In : Organic and Biomolecular Chemistry. 17, 17, p. 4359-4363 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

14-3-3 Proteins
peptides
Arginine
Fluorescence
proteins

A simple multi-scale model to evaluate left ventricular growth laws

Rondanina, E. & Bovendeerd, P., 2019, FIMH 2019: Functional Imaging and Modeling of the Heart. Coudière, Y., Ozenne, V., Vigmond, E. & Zemzemi, N. (eds.). Cham: Springer Nature Switzerland AG, p. 249-257 9 p. (Lecture Notes in Computer Science; vol. 11504)

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Mechanics
Blood

Association of improvement in fractional flow reserve with outcomes, including symptomatic relief, after percutaneous coronary intervention

Fournier, S., Ciccarelli, G., Toth, G. G., Milkas, A., Xaplanteris, P., Tonino, P. A. L., Fearon, W. F., Pijls, N. H. J., Barbato, E. & de Bruyne, B., 1 Apr 2019, In : JAMA Cardiology. 4, 4, p. 370-374 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Percutaneous Coronary Intervention
Angiography
Coronary Artery Disease
Randomized Controlled Trials
North America

A stirring system using suspended magnetically-actuated pillars for controlled cell clustering

Saberi, A., Zhang, S., van den Bersselaar, C., Kandail, H., den Toonder, J. M. J. & Kurniawan, N. A., 1 Jan 2019, In : Soft Matter. 15, 6, p. 1435-1443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

stirring
Magnetic scales
Colloids
Research laboratories
cells
1 Citation (Scopus)

A stochastic view on surface inhomogeneity of nanoparticles

Post, R. A. J., van der Zwaag, D., Bet, G., Wijnands, S. P. W., Albertazzi, L., Meijer, E. W. & van der Hofstad, R. W., 10 Apr 2019, In : Nature Communications. 10, 1, 11 p., 1663

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanoparticles
inhomogeneity
nanoparticles
Microscopy
Microscopic examination

A survey of crowdsourcing in medical image analysis

Ørting, S., Doyle, A., Hirth, M., van Hilten, A., Inel, O., Madan, C. R., Mavridis, P., Spiers, H. & Cheplygina, V., 25 Feb 2019, In : arXiv. 12 p., 1902.09159

Research output: Contribution to journalArticleAcademic

Open Access
File
Image analysis
Astrophysics
Medical imaging
Metadata
Learning algorithms

Atherosclerotic carotid bifurcation phantoms with stenotic soft inclusions for ultrasound flow and vessel wall elastography imaging

Chayer, B., van den Hoven, M., Roy Cardinal, M. H., Li, H., Swillens, A., Lopata, R. & Cloutier, G., 2 May 2019, In : Physics in Medicine and Biology. 64, 9, 12 p., 095025

Research output: Contribution to journalArticleAcademicpeer-review

Elasticity Imaging Techniques
Blood Vessels
Elastic Modulus
Internal Carotid Artery
Atherosclerotic Plaques
Nanosystems
Adenosine Triphosphate
Polylysine
Nanoreactors
Molecular interactions

Automatic cardiac landmark localization by a recurrent neural network

van Zon, M., Veta, M. & Li, S., 1 Jan 2019, Medical Imaging 2019: Image Processing. Landman, B. A. & Angelini, E. D. (eds.). Bellingham: SPIE, 13 p. 1094916. (Proceedings of SPIE; vol. 10949)

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

landmarks
Recurrent neural networks
Mitral Valve
Magnetic Resonance Spectroscopy
Magnetic resonance

Automatic classification of focal liver lesions based on MRI and risk factors

Jansen, M. J. A., Kuijf, H. J., Veldhuis, W. B., Wessels, F. J., Viergever, M. A. & Pluim, J. P. W., 2019, In : PLoS ONE. 14, 5, 13 p., e0217053

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
lesions (animal)
Liver
Magnetic resonance imaging
risk factors
liver

A value proposition for through level-based anti-TNFα drug dosing

Scharnhorst, V., Schmitz, E. M. H., van de Kerkhof, D., Derijks, L. J. J. & Broeren, M. A. C., 1 Feb 2019, In : Clinica Chimica Acta. 489, p. 89-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Monitoring
Pharmaceutical Preparations
Cost-Benefit Analysis
Therapeutics
Critical Pathways

A versatile protocol for studying anterior cruciate ligament reconstruction in a rabbit model

Hevesi, M., Crispim, J. F., Paggi, C. A., Dudakovic, A., van Genechten, W., Hewett, T., Kakar, S., Krych, A. J., van Wijnen, A. J. & Saris, D., 19 Mar 2019, In : Tissue Engineering Part C: Methods. 25, 4, p. 191-196 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Anterior Cruciate Ligament Reconstruction
Ligaments
Anterior Cruciate Ligament
Rabbits
Animal Care Committees

Benchmark on automatic 6-month-old infant brain segmentation algorithms: The iSeg-2017 Challenge

Wang, L., Nie, D., Li, G., Puybareau, E., Dolz, J., Zhang, Q., Wang, F., Xia, J., Wu, Z., Chen, J., Thung, K-H., Bui, T. D., Shin, J., Zeng, G., Zheng, G., Fonov, V. S., Doyle, A., Xu, Y., Moeskops, P., Pluim, J. P. W. & 9 othersDesrosiers, C., Ayed, I. B., Sanroma, G., Benkarim, O. M., Casamitjana, A., Vilaplana, V., Lin, W., Li, G. & Shen, D., 27 Feb 2019, In : IEEE Transactions on Medical Imaging.

Research output: Contribution to journalArticleAcademicpeer-review

Benchmarking
Brain
Magnetic resonance
Magnetic Resonance Spectroscopy
Cerebrospinal fluid

Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration

Castilho, M., Mouser, V., Chen, M., Malda, J. & Ito, K., 22 Jun 2019, In : Acta Biomaterialia.

Research output: Contribution to journalArticleAcademicpeer-review

Hydrogels
Cartilage
Articular Cartilage
Regeneration
Fibers

Biomechanics and modeling of tissue-engineered heart valves

Ristori, T., van Kelle, A. J. M., Baaijens, F. & Loerakker, S., 9 Apr 2019, Advances in heart valve biomechanics: valvular physiology, mechanobiology, and bioengineering. Sacks, M. & Liao, J. (eds.). Cham: Springer, p. 413-446 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Biomechanics
Tissue engineering
Tissue
Collagen
Heart valve prostheses

Biomedical applications of photo- and sono-activated Rose Bengal: a review

Vanerio, N., Stijnen, M., de Mol, B. A. J. M. & Kock, L. M., 1 Jul 2019, In : Photobiomodulation, Photomedicine, and Laser Surgery. 37, 7, p. 383-394 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Rose Bengal
Oncology
Xanthenes
Photodynamic therapy
Oxygen
2 Citations (Scopus)

Biomorphic engineering of multifunctional polylactide stomatocytes toward therapeutic nano-red blood cells

Shao, J., Pijpers, I. A. B., Cao, S., Williams, D. S., Yan, X., Li, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 1 Jan 2019, In : Advanced Science. 6, 5, 8 p., 1801678

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
erythrocytes
Blood
Erythrocytes
Cells
engineering

Bone-adhesive materials: clinical requirements, mechanisms of action, and future perspective

Sánchez-Fernández, M. J., Hammoudeh, H., Félix Lanao, R. P., van Erk, M., van Hest, J. C. M. & Leeuwenburgh, S. C. G., 22 Feb 2019, In : Advanced Materials Interfaces. 6, 4, 11 p., 1802021

Research output: Contribution to journalReview articleAcademicpeer-review

Adhesives
Bone
Biomaterials
Glues
Tissue

Bone microarchitecture and distal radius fracture pattern complexity

Daniels, A. M., Theelen, L. M. A., Wyers, C. E., Janzing, H. M. J., van Rietbergen, B., Vranken, L., van der Velde, R. Y., Geusens, P. P. M. M., Kaarsemaker, S., Poeze, M. & van den Bergh, J. P., 10 Jul 2019, In : Journal of Orthopaedic Research. 37, 8, p. 1690-1697

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Radius Fractures
Bone Density
Bone and Bones
Joints
Odds Ratio
3 Citations (Scopus)

Carbon nanotube reinforced supramolecular hydrogels for bioapplications

Mihajlovic, M., Mihajlovic, M., Dankers, P. Y. W., Masereeuw, R. & Sijbesma, R. P., 1 Jan 2019, In : Macromolecular Bioscience. 19, 12 p., 1800173

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Carbon Nanotubes
Hydrogels
Nanocomposites
Carbon nanotubes
Hydrogel

Cardiomyocyte contractile force changes in response to AGRWE detected by AFM

Qu, Y. M., Zhao, F., Wang, X., Liu, J., Li, J., Song, Z. & Wang, Z., 2 May 2019, In : Micro and Nano Letters. 14, 5, p. 511-514 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

atomic force microscopy
Water
water
synchronism
heart rate

Cats or CAT scans: transfer learning from natural or medical image source data sets?

Cheplygina, V., Mar 2019, In : Current Opinion in Biomedical Engineering. 9, p. 21-27

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
learning
tomography
image analysis
train
2 Citations (Scopus)
Open Access
File
Transcription
Telecommunication networks
Communication
Cells
Networks (circuits)

Characteristics of surgical prosthetic heart valves and problems around labelling: a document from the European Association for Cardio-Thoracic Surgery (EACTS)-the society of thoracic surgeons (STS)-american association for thoracic surgery (AATS) valve labelling task force

Durko, A. P., Head, S. J., Pibarot, P., Atluri, P., Bapat, V., Cameron, D. E., Casselman, F. P. A., Chen, E. P., Dahle, G., Ebels, T., Elefteriades, J. A., Lancellotti, P., Prager, R. L., Rosenhek, R., Speir, A., Stijnen, M., Tasca, G., Yoganathan, A., Walther, T. & de Paulis, R., 1 Jun 2019, In : European Journal of Cardio-Thoracic Surgery. 55, 6, p. 1025-1036 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Heart Valves
Advisory Committees
Thoracic Surgery
Thorax
Organizations
Heart Valves
Advisory Committees
Thoracic Surgery
Thorax
Organizations

Characteristics of the retinal microvasculature in association with cardiovascular risk markers in children with overweight, obesity and morbid obesity

Berendschot, T. T. J. M., Rijks, J., Vreugdenhil, A., Dorenbos, E., Karnebeek, K., Joris, P., Mensink, R. & Plat, J., 2019, In : Journal of Vascular Research. 56, S1, p. 13-13

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
1 Citation (Scopus)

CHD1 loss alters AR binding at lineage-specific enhancers and modulates distinct transcriptional programs to drive prostate tumorigenesis

Augello, M. A., Liu, D., Deonarine, L. D., Robinson, B. D., Huang, D., Stelloo, S., Blattner, M., Doane, A. S., Wong, E. W. P., Chen, Y., Rubin, M. A., Beltran, H., Elemento, O., Bergman, A. M., Zwart, W., Sboner, A., Dephoure, N. & Barbieri, C. E., 15 Apr 2019, In : Cancer Cell. 35, 4, p. 603-617

Research output: Contribution to journalArticleAcademicpeer-review

Androgen Receptors
Prostate
Carcinogenesis
Neoplasms
Prostatic Neoplasms

Chemoenzymatic synthesis of sialic acid derivatives using immobilized N-acetylneuraminate lyase in a continuous flow reactor

Bloemendal, V. R. L. J., Moons, S. J., Heming, J. J. A., Chayoua, M., Niesink, O., van Hest, J. C. M., Boltje, T. J. & Rutjes, F. P. J. T., 8 May 2019, In : Advanced Synthesis and Catalysis. 361, 11, p. 2443-2447

Research output: Contribution to journalArticleAcademicpeer-review

N-acetylneuraminate lyase
N-Acetylneuraminic Acid
Derivatives
Acids
Sialic Acids
1 Citation (Scopus)

Clinical candidates modulating protein-protein interactions: the fragment-based experience

Valenti, D., Hristeva, S., Tzalis, D. & Ottmann, C., 1 Apr 2019, In : European Journal of Medicinal Chemistry. 167, p. 76-95 20 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Proteins
Modulators
Lead compounds
Drug Discovery
Chemical properties