• Groene Loper, Building 15, Gemini South (room 2.106)

    5612 AZ Eindhoven

    Netherlands

Organization profile

Introduction / mission

We aim to improve our qualitative and quantitative knowledge of biomedical processes and structures and diseases.

Highlighted phrase

Simulations, modeling and informatics

Organisational profile

We want to improve our qualitative and quantitative knowledge of biomedical processes and structures (such as biomembranes, protein interactions and complex biochemical networks) and diseases (such as metabolic syndrome and diabetes). In our research group we distinguish five research topics: molecular simulations, systems biology, synthetic biology, bioinformatics and mathematical modeling.

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1982 2018

4 Citations

A microfluidics platform for combinatorial drug screening on cancer biopsies

Eduati, F., Utharala, R., Madhavan, D., Neumann, U. P., Longerich, T., Cramer, T., Saez-Rodriguez, J. & Merten, C. A., 22 Jun 2018, In : Nature Communications. 9, 1, 13 p., 2434

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Preclinical Drug Evaluations
Microfluidics
Biopsy
Drug Combinations
Tumors

Applications of Canonical Correlation Analysis to microbial and metabolite data of metabolic syndrome patients

van der Stam, J. A., Prodan, A., van Baar, A., Hilbers, P. A. J., Groen, B., Nieuwdorp, M., Levin, E. & van Riel, N. A. W., 15 May 2018

Research output: Contribution to conferencePosterAcademic

Open Access
File

Prizes

AMC Principal Investigator

Natal van Riel (Recipient), 1 May 2016

Recognition: OtherCareer, activity or publication related prizes (lifetime, best paper, poster etc.)Scientific

Best poster award

Yvonne Rozendaal (Recipient), 28 Oct 2016

Recognition: OtherCareer, activity or publication related prizes (lifetime, best paper, poster etc.)Scientific

Heart Neoplasms
Practice Guidelines
Chronic Disease
Stroke
Myocardial Infarction

Activities 1999 2018

Personalized modelling of bile acid metabolism: predicting metabolic effects of bariatric surgery

van Riel, N. (Speaker)
6 Jul 2018

Activity: Talk or presentationInvited talkScientific

A physiology based glucose-insulin-GLP-1 model: explaining changes observed after Roux-en-Y gastric bypass

L.C.P. Thijssen (Speaker), van Riel, N. (Member)
15 May 2018

Activity: Talk or presentationContributed talkScientific

4th Dutch Bioinformatics & Systems Biology Conference

van Riel, N. (Organiser)
15 May 201816 May 2018

Activity: Participating in or organising an eventConferenceScientific

Press / Media

Miniature testing of drug pairs on tumour biopsies

Federica Eduati

25/06/18

1 item of media coverage

Press/Media: Expert Comment

Miniature Testing of Drug Pairs on Tumour Biopsies

Federica Eduati

25/06/18

1 item of media coverage

Press/Media: Expert Comment

Miniature testing of drug pairs on tumor biopsies

Federica Eduati

22/06/18

1 item of media coverage

Press/Media: Expert Comment

Research areas

Bioinformatics

Rina van Dijck - Postma (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)

Impact: Research Topic/Theme (at group level)

Cancer Systems Biology

Rina van Dijck - Postma (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)

Impact: Research Topic/Theme (at group level)

Mathematical Modeling

Rina van Dijck - Postma (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)

Impact: Research Topic/Theme (at group level)

Student theses

Causal candidate genes identification for familial hypercholesterolemia family based on whole-genome sequencing

Author: Wang, Q., 31 Aug 2017

Supervisor: Hilbers, P. (Supervisor 1), van Riel, N. (Supervisor 2), Hovingh, K. (External person) (External coach), Bosnacki, D. (Supervisor 2) & Veta, M. (Supervisor 2)

Student thesis: Master

Data mining and analysis for the insulin signalling pathway

Author: Rozendaal, Y., Jul 2011

Supervisor: Çölmekçi, C. (Supervisor 1) & van Riel, N. (Supervisor 1)

Student thesis: Bachelor

Downstream coupling of PEN-based chemical reaction networks

Author: van der Zee, D., 31 Aug 2017

Supervisor: van Roekel, H. (Supervisor 1) & de Greef, T. (Supervisor 2)

Student thesis: Master