Content available in repository
Content available in repository
Organisation profile
Introduction / mission
In this group, research deals with chemical biology approaches to study protein-protein interactions.
Highlighted phrase
supramolecular architecture and drug discovery
Organisation profile
The Chemical Biology group is a research group within the department of Biomedical Engineering. The group is supervized by Prof.dr.ir. Luc Brunsveld.
In this group, research deals with chemical biology approaches to study protein-protein interactions. The two general lines that are being followed are supramolecular architecture and drug discovery.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy -
SDG 14 Life Below Water
Fingerprint
Dive into the research topics where Chemical Biology is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Linn van den Aker
- Biomedical Engineering, Chemical Biology - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Blaž Andlovic, MSc
- Biomedical Engineering, Chemical Biology - Former Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Roy Blom
- Biomedical Engineering, Chemical Biology - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
Research output
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A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator
Zaalberg, A., Lacoste, A., Minnee, E., Mayayo-Peralta, I., Schuurman, K., Gregoricchio, S., van Schaik, T. A., Hoekman, L., Li, D., Corey, E., Janssen, H., Lieftink, C., Prekovic, S., Proost, N., van de Ven, M., Zander, S., Altelaar, M., Nelson, P. S., Beijersbergen, R. L. & Zwart, W. (Corresponding author-nrf) & 1 others, , 28 Jul 2026, In: Oncogene. 45, 36, p. 3797-3811 15 p.Research output: Contribution to journal › Article › Academic › peer-review
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Beyond Molecular Structures: Investigating Demographic Factors in Drug-Induced Cardiotoxicity Prediction Models
Iwan, M. (Corresponding author), Roncaglioni, A. & Grisoni, F., 22 Jun 2026, In: Journal of Chemical Information and Modeling. 66, 12, p. 6962-6971 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Coacervates in the Era of Autonomous Experimentation: From Empirical Formulation to Self-Driving Laboratories
Leurs, Y. H. A., 13 Oct 2026, (Accepted/In press) Eindhoven: Eindhoven University of Technology. 204 p.Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
Open AccessFile
Equipment
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Laboratory for Chemical Biology
Brunsveld, L. (Manager)
Chemical BiologyFacility/equipment: Research lab
Datasets
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CCDC 2183726: Experimental Crystal Structure Determination
Maurya, G. P. (Contributor), Verma, D. (Contributor), Sinha, A. (Contributor), Brunsveld, L. (Contributor) & Haridas, V. (Contributor), Cambridge Crystallographic Data Centre, 7 Apr 2022
DOI: 10.5517/ccdc.csd.cc2c9bst
Dataset
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CCDC 2183727: Experimental Crystal Structure Determination
Maurya, G. P. (Contributor), Verma, D. (Contributor), Sinha, A. (Contributor), Brunsveld, L. (Contributor) & Haridas, V. (Contributor), Cambridge Crystallographic Data Centre, 7 Apr 2022
DOI: 10.5517/ccdc.csd.cc2c9btv
Dataset
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CCDC 2183728: Experimental Crystal Structure Determination
Maurya, G. P. (Contributor), Verma, D. (Contributor), Sinha, A. (Contributor), Brunsveld, L. (Contributor) & Haridas, V. (Contributor), Cambridge Crystallographic Data Centre, 4 Jul 2022
DOI: 10.5517/ccdc.csd.cc2c9bvw
Dataset
Prizes
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Golden Medal Royal Dutch Chemical Society 2012
Brunsveld, L. (Recipient), 2012
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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NWO Vici Award : Synthetic Supramolecular Signalling Systems
Brunsveld, L. (Recipient), 2014
Prize: NWO › Vici › Scientific
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NWO Vidi Award : Pieces of plastic with biological properties?
Dankers, P. Y. W. (Recipient), 2016
Prize: NWO › Vidi › Scientific
Press/Media
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Artificial Cell Communication: Protein on Demand
Hazegh Nikroo, A., Altenburg, W. J., van Veldhuisen, T. W., Brunsveld, L. & van Hest, J. C. M.
17/10/24
2 items of Media coverage
Press/Media: Expert Comment
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Investigators from QILU University of Technology Have Reported New Data on Extracellular Matrix Proteins (Thermoplastic Collagen Fiber Films Improved By Bacterial Cellulose With High Barrier Properties)
Yang, S.
18/10/23
1 item of Media coverage
Press/Media: Expert Comment
Research areas
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14-3-3 Protein-Protein Interactions
van Hoof, M. (Content manager), Broeders, A. (Content manager) & van Gorp, L. (Content manager)
Impact: Research Topic/Theme (at group level)
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Nuclear Receptor-Cofactor Interaction
van Hoof, M. (Content manager), Broeders, A. (Content manager) & van Gorp, L. (Content manager)
Impact: Research Topic/Theme (at group level)
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Supramolecular Architectures
van Hoof, M. (Content manager), Broeders, A. (Content manager) & van Gorp, L. (Content manager)
Impact: Research Topic/Theme (at group level)
Student theses
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1,4,7-triazacyclononane functionalized BTA: a supramolecular polymer for cooperative catalysis
Robeerst, C. J. (Author), Mabesoone, M. (Supervisor 1), Su, L. (Supervisor 2), Meijer, B. (Supervisor 2), Palmans, A. (Supervisor 2) & Schenning, A. (Supervisor 2), 26 Jun 2019Student thesis: Master
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A Comparative Study of Ligand-Based and Structure-Based Models in De Novo Drug Design with Active and Inactive Ligands
Groffen, I. (Author), Tomczak, J. (Supervisor 1), van Tilborg, D. (Supervisor 2) & Grisoni, F. (Supervisor 2), 27 Aug 2024Student thesis: Master
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Active learning for drug discovery using graph neural networks
Rossen, L. (Author), Brunsveld, L. (Supervisor 1), Grisoni, F. (Supervisor 2), Markvoort, A. J. (Supervisor 2) & van Tilborg, D. (Supervisor 2), 30 Nov 2023Student thesis: Master