• De Groene Loper 3, Helix

    5612 AE Eindhoven

    Netherlands

  • P.O. Box 513, Deparment of Biomedical Engineering

    5600 MB Eindhoven

    Netherlands

Organization profile

Introduction / mission

In this group, research deals with chemical biology approaches to study protein-protein interactions.

Highlighted phrase

supramolecular architecture and drug discovery

Organisational profile

The Chemical Biology group is a research group within the department of Biomedical Engineering. The group is supervized by Prof.dr.ir. Luc Brunsveld.
In this group, research deals with chemical biology approaches to study protein-protein interactions. The two general lines that are being followed are supramolecular architecture and drug discovery.

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

Photo of Alice Ballone

Alice Ballone

Person: Prom. : doctoral candidate (PhD)

20182018
No photo of Arjen-Kars Boer

Arjen-Kars Boer

Person: OWP : University Teacher / Researcher

20152019

Research Output 1990 2019

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation

Korkmaz, G., Manber, Z., Lopes, R., Prekovic, S., Schuurman, K., Kim, Y., Teunissen, H., Flach, K., Wit, E. D., Galli, G. G., Zwart, W., Elkon, R. & Agami, R., 10 Oct 2019, In : Nucleic Acids Research. 47, 18, p. 9557-9572 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Estrogen Receptor alpha
Estrogen Receptors
Cell Proliferation
Breast Neoplasms

Adherence to dabigatran etexilate in atrial fibrillation patients intended to undergo electrical cardioversion

Comuth, W. J., de Maat, M. P. M., van de Kerkhof, D., Malczynski, J., Husted, S., Kristensen, S. D. & Münster, A. M. B., 1 Apr 2019, In : European Heart Journal - Cardiovascular Pharmacotherapy. 5, 2, p. 91-99 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Electric Countershock
Atrial Fibrillation
Medication Adherence
Therapeutics
Dabigatran

A DNA-based synthetic apoptosome

Rosier, B., Markvoort, B., Gumi Audenis, B., Roodhuizen, J., Brunsveld, L. & de Greef, T. F. A., 2019, (Accepted/In press) In : Nature Catalysis.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Apoptosomes
Caspase 9
DNA
Proteins
Enzymes

Equipment

Laboratory for Chemical Biology

Luc Brunsveld (Manager)

Chemical Biology

Facility/equipment: Research lab

Prizes

Golden Medal Royal Dutch Chemical Society 2012

Luc Brunsveld (Recipient), 2012

Recognition: OtherCareer, activity or publication related prizes (lifetime, best paper, poster etc.)Scientific

NWO Vici Award : Synthetic Supramolecular Signalling Systems

Luc Brunsveld (Recipient), 2014

Recognition: NWOViciScientific

Biomolecules

Research Center for Functional Molecular Systems

Bert Meijer (Recipient), Jan van Hest (Recipient), Luc Brunsveld (Recipient), Rene Janssen (Recipient) & Rint Sijbesma (Recipient), 2013

Recognition: NWOGravitationScientific

Netherlands
selection procedure
Ministry of Education
funding
organization

Press / Media

2 million euros for cancer research Netherlands Cancer Institute

Wilbert Zwart

3/07/19

1 item of media coverage

Press/Media: Expert Comment

Highway to help scientific findings to clinic

Wilbert Zwart

7/05/19

1 item of media coverage

Press/Media: Expert Comment

Wilbert Zwart receives ASPIRE award for drug test on 3D printed matrix

Wilbert Zwart

12/03/19

1 item of media coverage

Press/Media: Expert Comment

Research areas

14-3-3 Protein-Protein Interactions

Marjo van Hoof (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)

Impact: Research Topic/Theme (at group level)

Nuclear Receptor-Cofactor Interaction

Marjo van Hoof (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)

Impact: Research Topic/Theme (at group level)

Supramolecular Architectures

Marjo van Hoof (Content manager), Amy Broeders (Content manager), Lieke van Gorp (Content manager)

Impact: Research Topic/Theme (at group level)

Student theses

Bioluminescent antibody conjugates for direct detection of analytes in solution

Author: van Aalen, E., 28 Mar 2019

Supervisor: Ni, Y. (Supervisor 1) & Merkx, M. (Supervisor 2)

Student thesis: Master

Biomarkers as predictor of quality of life in bariatric patients

Author: Schouten, J., 31 Jan 2019

Supervisor: Hilbers, P. (Supervisor 1), van Riel, N. (Supervisor 2), Scharnhorst, V. (Supervisor 2), van Loon, S. (Supervisor 2) & Deneer, R. (Supervisor 2)

Student thesis: Master

Characterization of the interaction between 14-3-3 and the R-domain of CFTR

Author: van de Sande, M., 29 Mar 2018

Supervisor: Stevers, L. (Supervisor 1) & Brunsveld, L. (Supervisor 2)

Student thesis: Master