Content available in repository
Content available in repository
Organisation profile
Introduction / mission
In this group, research deals with chemical biology approaches to study protein-protein interactions.
Highlighted phrase
supramolecular architecture and drug discovery
Organisational profile
The Chemical Biology group is a research group within the department of Biomedical Engineering. The group is supervized by Prof.dr.ir. Luc Brunsveld.
In this group, research deals with chemical biology approaches to study protein-protein interactions. The two general lines that are being followed are supramolecular architecture and drug discovery.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Chemical Biology is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Blaz Andlovic, MSc
- Biomedical Engineering, Chemical Biology - Former Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Arjen-Kars Boer
- Biomedical Engineering, Chemical Biology - University Researcher
- EAISI Health - University Researcher
Person: OWP : University Teacher / Researcher
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Bas Bögels
- Biomedical Engineering, Biomodelling - Doctoral Candidate
- Biomedical Engineering, Chemical Biology - Doctoral Candidate
- Biomedical Engineering, Synthetic Biology - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
Research output
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Advancing prostate cancer therapies through integrative multi-omics: It’s about time
Linder, S., 30 Jun 2023, Eindhoven: Eindhoven University of Technology. 255 p.Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
Open AccessFile -
Analysis of Neuron–Specific enolase isozymes in human serum using immunoaffinity purification and liquid chromatography–tandem mass spectrometry quantification
Genet, S. A. A. M., Wolfs, J. R. E., Vu, C. B. A. K., Wolter, M., Broeren, M. A. C., van Dongen, J., Brunsveld, L., Scharnhorst, V. & van de Kerkhof, D., 15 May 2023, In: Journal of Chromatography, B, Analytical Technologies in the Biomedical and Life Sciences. 1223, 7 p., 123701.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Downloads (Pure) -
A Synthetic Protocell‐Based Heparin Scavenger
Liu, Q., Yang, S., Seitz, I., Makri Pistikou, A-M., de Greef, T. F. A. & Kostiainen, M., 29 Mar 2023, In: Small : Nano Micro. 19, 13, 6 p., e2201790.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)17 Downloads (Pure)
Equipment
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Laboratory for Chemical Biology
L. Brunsveld (Manager)
Chemical BiologyFacility/equipment: Research lab
Datasets
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Functional mapping of androgen receptor enhancer activity
Zwart, W. T. (Creator), Linder, S. (Creator), Huang, C. F. (Creator), Le Bihan, S. (Contributor), Hach, F. (Contributor), Altintas, U. B. (Creator), Lack, N. A. (Creator), Ozturan, D. (Contributor), Collins, C. (Creator), Gokbayrak, B. (Contributor), Hoogstraat, M. (Creator), Saffarzadeh, M. (Contributor), Sar, F. (Creator), Bergman, A. M. (Creator), Stelloo, S. (Creator), Lingadahalli, S. (Contributor), Gleave, M. E. (Creator), van der Poel, H. (Contributor), Morova, T. (Contributor), McConeghy, B. (Creator), Hu, E. (Creator), Yu, I. P. L. (Creator), Feng, F. Y. (Creator) & Emberly, E. (Creator), Figshare, 12 May 2021
DOI: 10.6084/m9.figshare.c.5421005, https://springernature.figshare.com/collections/Functional_mapping_of_androgen_receptor_enhancer_activity/5421005
Dataset
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Additional file 3 of Functional mapping of androgen receptor enhancer activity
Bergman, A. M. (Creator), Huang, C. F. (Creator), Linder, S. (Creator), Hoogstraat, M. (Creator), Altintas, U. B. (Creator), Lack, N. A. (Creator), van der Poel, H. (Contributor), Hach, F. (Contributor), Emberly, E. (Creator), Hu, E. (Creator), Yu, I. P. L. (Creator), Feng, F. Y. (Creator), McConeghy, B. (Creator), Morova, T. (Contributor), Sar, F. (Creator), Gleave, M. E. (Creator), Collins, C. (Creator), Saffarzadeh, M. (Contributor), Lingadahalli, S. (Contributor), Le Bihan, S. (Contributor), Ozturan, D. (Contributor), Zwart, W. T. (Creator), Stelloo, S. (Creator) & Gokbayrak, B. (Contributor), Figshare, 12 May 2021
DOI: 10.6084/m9.figshare.14576603, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Functional_mapping_of_androgen_receptor_enhancer_activity/14576603
Dataset
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Additional file 4 of Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer
Severson, T. (Creator), Qiu, X. (Creator), Alshalalfa, M. (Creator), Sjöström, M. (Creator), Quigley, D. (Creator), Bergman, A. (Creator), Long, H. (Creator), Feng, F. (Creator), Freedman, M. L. (Creator), Zwart, W. T. (Creator) & Pomerantz, M. M. (Creator), Figshare, 5 May 2022
DOI: 10.6084/m9.figshare.19711181, https://springernature.figshare.com/articles/dataset/Additional_file_4_of_Androgen_receptor_reprogramming_demarcates_prognostic_context-dependent_gene_sets_in_primary_and_metastatic_prostate_cancer/19711181
Dataset
Prizes
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Golden Medal Royal Dutch Chemical Society 2012
Brunsveld, Luc (Recipient), 2012
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific
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NWO Vici Award : Synthetic Supramolecular Signalling Systems
Brunsveld, Luc (Recipient), 2014
Prize: NWO › Vici › Scientific
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NWO Vidi Award : Pieces of plastic with biological properties?
Dankers, Patricia Y.W. (Recipient), 2016
Prize: NWO › Vidi › Scientific
Press/Media
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Eindhoven University of Technology Researcher Details Research in Prostate Cancer (Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model)
Wilbert T. Zwart & Federica Eduati
18/08/23
1 item of Media coverage
Press/Media: Expert Comment
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Multi-Omics Research Reveals Surprising Protein’s Role in Prostate Cancer Treatment Resistance
4/07/23
1 item of Media coverage
Press/Media: Expert Comment
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Impacts
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14-3-3 Protein-Protein Interactions
Marjo van Hoof (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
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Nuclear Receptor-Cofactor Interaction
Marjo van Hoof (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
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Supramolecular Architectures
Marjo van Hoof (Content manager), Amy Broeders (Content manager) & Lieke van Gorp (Content manager)
Impact: Research Topic/Theme (at group level)
Student theses
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1,4,7-triazacyclononane functionalized BTA: a supramolecular polymer for cooperative catalysis
Author: Robeerst, C. J., 26 Jun 2019Supervisor: Mabesoone, M. (Supervisor 1), Su, L. (Supervisor 2), Meijer, B. (Supervisor 2), Palmans, A. (Supervisor 2) & Schenning, A. (Supervisor 2)
Student thesis: Master
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A general framework for straightforward model construction of multi-component thermodynamic equilibrium systems
Author: Geertjens, N. H. J., 28 Feb 2022Supervisor: Wezeman, T. (Supervisor 1) & Brunsveld, L. (Supervisor 2)
Student thesis: Master
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A molecular dynamic simulation and machine learning study of counterion dependent DNA origami stability
Author: van Dalen, S. L., 25 Aug 2022Supervisor: Hilbers, P. A. J. (Supervisor 1), Markvoort, A. J. (Supervisor 2) & Grisoni, F. (Supervisor 2)
Student thesis: Master