• Groene Loper 15, Gemini-Zuid 3.115

    5612 AZ Eindhoven

    Netherlands

Organization profile

Introduction / mission

MRI and MRS offer exciting possibilities for the investigation of a range of structural, functional and metabolic parameters in living systems.

MRI and MRS are non-invasive and therefore ideally suited for repeated studies, in which changes in tissues are followed over time. This non-invasiveness and the richness of the information that is obtained explain the important role of MR in biological and biomedical research. Not surprisingly, MR has also rapidly gained an important position in human healthcare since its first arrival in medical centers in the late 1980’s.

Highlighted phrase

The research and teaching program of the BioMedical NMR group is aimed at the development and use of in vivo magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques. 

Organisational profile

The central aim of our research program is to push the limits of biomedical MR. New techniques are developed and validated by studies on biological preparations in vitro and animal models in vivo, and where possible applied in clinical human research. The technology developments in our group are inspired by important biomedical and healthcare problems:

  1. skeletal muscle disorders, especially type 2 diabetes and decubitus;
  2. cardiovascular disorders, including atherosclerosis and cardiac infarction;
  3. molecular imaging of disease biomarkers and the development of target-specific contrast agents.

These themes were chosen because:

  1. diseases of skeletal muscle and the cardiovascular system have a major socio-economic impact;
  2. MR has the potential to greatly improve the diagnosis and management of these disorders;
  3. novel MRI protocols combined with targeted contrast agents can strongly enhance the specificity and sensitivity of diagnostic MRI.

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

No photo of Ot Bakermans

Ot Bakermans

Person: OWP : University Teacher / Researcher

20112015
Photo of Holger Grüll
20072019
No photo of Jules L. Nelissen

Jules L. Nelissen

Person: OWP : University Teacher / Researcher

20142019

Research Output 1978 2019

2 Citations (Scopus)

Analysis of chemical exchange saturation transfer contributions from brain metabolites to the Z-spectra at various field strengths and pH

Khlebnikov, V., van der Kemp, W. J. M., Hoogduin, H., Klomp, D. W. J. & Prompers, J. J., 31 Jan 2019, In : Scientific Reports. 9, 11 p., 1089

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

An iterative sparse deconvolution method for simultaneous multicolor 19F-MRI of multiple contrast agents

Schoormans, J., Calcagno, C., Daal, M. R. R., Wüst, R. C. I., Faries, C., Maier, A., Teunissen, A. J. P., Naidu, S., Sanchez-Gaytan, B. L., Nederveen, A. J., Fayad, Z. A., Mulder, W. J. M., Coolen, B. F. & Strijkers, G. J., 10 Jul 2019, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Contrast Media
Artifacts
Fluorine
Noise
Cell Tracking

Correction to: imaging of tumor spheroids, dual-isotope SPECT, and autoradiographic analysis to assess the tumor uptake and distribution of different nanobodies

Beltrán Hernández, I., Rompen, R., Rossin, R., Xenaki, K. T., Katrukha, E. A., Nicolay, K., Henegouwen, P. V. B. E., Grüll, H. & Oliveira, S., 15 Apr 2019, In : Molecular Imaging and Biology. 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access
Single-Domain Antibodies
Single-Photon Emission-Computed Tomography
Isotopes
Neoplasms

Prizes

NWO Veni Award : Changes in the failing heart

M.W. Nabben (Recipient), 2013

Recognition: NWOVeniScientific

Heart Diseases
Heart Failure
Research Personnel
Therapeutics

Press / Media

Skull Surprise

Katrien Vandoorne

30/08/18

1 item of media coverage

Press/Media: Expert Comment

Student theses

Cerebral activation reflects loudness perception rather than physical sound intensity: an fMRI study in normally hearing and hearing-impaired subjects

Author: Schoenmaker, E., 28 Feb 2005

Supervisor: Langers, D. (Supervisor 1), Backes, W. (Supervisor 2), van Dijk, P. (Supervisor 2), Manni, J. (External person) (Supervisor 2), van Engelshoven, J. M. (Supervisor 2) & Nicolay, K. (Supervisor 2)

Student thesis: Master

Development of protein-liposome conjugates using native chemical ligation

Author: Brusselaars, W., 2007

Supervisor: Reulen, S. (Supervisor 1), Merkx, M. (Supervisor 2), Meijer, B. (Supervisor 2), Sommerdijk, N. (Supervisor 2) & Nicolaij, K. (Supervisor 2)

Student thesis: Master

Machnetic resonance neurograpy of the celiac plexus with motion-compensated 3D SHINKEI

Author: Kok, L., 20 Jun 2017

Supervisor: Strijkers, G. (Supervisor 1), Ferrer, C. (External person) (External coach), Bos, C. (External person) (External coach), van Leeuwen, M. (External person) (External coach) & Lopata, R. (Supervisor 2)

Student thesis: Master