• Groene Loper 15, Gemini-Zuid 3.115

    5612 AZ Eindhoven

    Netherlands

Organization profile

Introduction / mission

MRI and MRS offer exciting possibilities for the investigation of a range of structural, functional and metabolic parameters in living systems.

MRI and MRS are non-invasive and therefore ideally suited for repeated studies, in which changes in tissues are followed over time. This non-invasiveness and the richness of the information that is obtained explain the important role of MR in biological and biomedical research. Not surprisingly, MR has also rapidly gained an important position in human healthcare since its first arrival in medical centers in the late 1980’s.

Highlighted phrase

The research and teaching program of the BioMedical NMR group is aimed at the development and use of in vivo magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques. 

Organisational profile

The central aim of our research program is to push the limits of biomedical MR. New techniques are developed and validated by studies on biological preparations in vitro and animal models in vivo, and where possible applied in clinical human research. The technology developments in our group are inspired by important biomedical and healthcare problems:

  1. skeletal muscle disorders, especially type 2 diabetes and decubitus;
  2. cardiovascular disorders, including atherosclerosis and cardiac infarction;
  3. molecular imaging of disease biomarkers and the development of target-specific contrast agents.

These themes were chosen because:

  1. diseases of skeletal muscle and the cardiovascular system have a major socio-economic impact;
  2. MR has the potential to greatly improve the diagnosis and management of these disorders;
  3. novel MRI protocols combined with targeted contrast agents can strongly enhance the specificity and sensitivity of diagnostic MRI.

Fingerprint Dive into the research topics where Biomedical NMR is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

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    Profiles

    No photo of Ot Bakermans

    Ot Bakermans

    Person: OWP : University Teacher / Researcher

    20112015
    Photo of Holger Grüll
    20072020
    No photo of Jules L. Nelissen

    Jules L. Nelissen

    Person: OWP : University Teacher / Researcher

    20142019

    Research Output

    31P magnetic resonance spectroscopy in skeletal muscle: experts' consensus recommendations

    Experts' Working Group on 31P MR Spectroscopy of Skeletal Muscle, Meyerspeer, M., Jeneson, J. A. L. & Prompers, J. J., 1 Jan 2020, (Accepted/In press) In : NMR in Biomedicine. e4246.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 2 Citations (Scopus)

    Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging

    de Bruijn, H. S., Mashayekhi, V., Schreurs, T. J. L., van Driel, P. B. A. A., Strijkers, G. J., van Diest, P. J., Lowik, C. W. G. M., Seynhaeve, A. L. B., Hagen, T. L. M. T., Prompers, J. J., van Bergen en Henegouwen, P. M. P., Robinson, D. J. & Oliveira, S., 1 Jan 2020, In : Theranostics. 10, 5, p. 2436-2452 17 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 2 Citations (Scopus)

    Correction to: Imaging of Tumor Spheroids, Dual-Isotope SPECT, and Autoradiographic Analysis to Assess the Tumor Uptake and Distribution of Different Nanobodies (Molecular Imaging and Biology, (2019), 21, 6, (1079-1088), 10.1007/s11307-019-01320-x)

    Beltrán Hernández, I., Rompen, R., Rossin, R., Xenaki, K. T., Katrukha, E. A., Nicolay, K., Henegouwen, P. V. B. E., Grüll, H. & Oliveira, S., 1 Feb 2020, In : Molecular Imaging and Biology. 22, 1, p. 217 1 p.

    Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

    Open Access
  • Prizes

    NWO Veni Award : Changes in the failing heart

    M.W. Nabben (Recipient), 2013

    Prize: NWOVeniScientific

  • Press / Media

    Skull Surprise

    K. Vandoorne

    30/08/18

    1 item of Media coverage

    Press/Media: Expert Comment

    Student theses

    Cerebral activation reflects loudness perception rather than physical sound intensity: an fMRI study in normally hearing and hearing-impaired subjects

    Author: Schoenmaker, E., 28 Feb 2005

    Supervisor: Langers, D. (Supervisor 1), Backes, W. (Supervisor 2), van Dijk, P. (Supervisor 2), Manni, J. (External person) (Supervisor 2), van Engelshoven, J. M. (Supervisor 2) & Nicolay, K. (Supervisor 2)

    Student thesis: Master

    Development of protein-liposome conjugates using native chemical ligation

    Author: Brusselaars, W., 2007

    Supervisor: Reulen, S. (Supervisor 1), Merkx, M. (Supervisor 2), Meijer, B. (Supervisor 2), Sommerdijk, N. (Supervisor 2) & Nicolaij, K. (Supervisor 2)

    Student thesis: Master

    Machnetic resonance neurograpy of the celiac plexus with motion-compensated 3D SHINKEI

    Author: Kok, L., 20 Jun 2017

    Supervisor: Strijkers, G. (Supervisor 1), Ferrer, C. (External person) (External coach), Bos, C. (External person) (External coach), van Leeuwen, M. (External person) (External coach) & Lopata, R. (Supervisor 2)

    Student thesis: Master