Biomedical Materials and Chemistry

  • Institute for Complex Molecular Systems Department of Biomedical Engineering, P.O. Box 513

    5600 MB Eindhoven

    Netherlands

Organization profile

Introduction / mission

To provide material solutions for regenerative medicine through development of functional biomaterials based on supramolecular chemistry.

Highlighted phrase

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials.

Organisational profile

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials. The main goals are: 1. To develop methods to specifically modify biomaterials surfaces, and 2. To translate these biomaterials to applications in the field of regenerative medicine, with a focus on cardiovascular and renal applications.

The biomedical application of different supramolecular polymeric biomaterials held together via directed, non-covalent interactions is the central theme. In the cardiovascular field the aim is to develop vascular grafts and heart valves that in situ can be engineered by selective capturing of progenitor cells from the blood (in close collaboration with prof. Carlijn Bouten). Additionally, catheter-delivery methods of various drugs, cells and exosomes, encapsulated in hydrogels, to the heart after myocardial infarction are investigated. Furthermore, the Biomaterials research group also designs and develops biomaterials to intervene in processes related to kidney disease. In order to ameliorate hemodialysis bilayered supramolecular membranes on which kidney cells can be cultured outside the body are developed.

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    Research Output

    • 33 Article
    • 9 Phd Thesis 1 (Research TU/e / Graduation TU/e)
    • 1 Chapter
    • 1 Editorial

    Development of poor cell adhesive immersion precipitation membranes based on supramolecular bis-urea polymers

    van Gaal, R. C., van Sprang, J. F., Borneman, Z. & Dankers, P. Y. W., 1 Mar 2020, In : Macromolecular Bioscience. 20, 3, 7 p., 1900277.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 2 Downloads (Pure)

    Functional supramolecular bioactivated electrospun mesh improves tissue ingrowth in experimental abdominal wall reconstruction in rats

    Mori da Cunha, M. G. M. C., Arts, B., Hympanova, L., Rynkevic, R., Mackova, K., Bosman, A. W., Dankers, P. Y. W. & Deprest, J., 1 Apr 2020, In : Acta Biomaterialia. 106, p. 82-91 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • Open Access
    File
  • 15 Downloads (Pure)

    Prizes

    NWO Vidi Award : Pieces of plastic with biological properties?

    P.Y.W. Dankers (Recipient), 2016

    Prize: NWOVidiScientific

  • Supramolecular hydrogels as local controlled drug delivery carriers

    P.Y.W. Dankers (Recipient), 2016

    Prize: ERCProof of conceptScientific

  • Press / Media

    The NWO Chemistry Round Table: an introduction

    Patricia Y.W. Dankers & Rolf A.T.M. van Benthem

    26/11/19

    1 item of Media coverage

    Press/Media: Expert Comment

    Bert Weckhuysen steps down as chair of the Chemistry Round Table

    Patricia Y.W. Dankers

    11/10/19

    1 item of Media coverage

    Press/Media: Expert Comment

    Student theses

    Decellularized extracellular matrix hydrogels for kidney tissue culture

    Author: Smits, I., 27 Feb 2020

    Supervisor: van Sprang, J. F. (Supervisor 1), van Gaal, R. C. (Supervisor 2) & Dankers, P. Y. (Supervisor 2)

    Student thesis: Master

    Introduction of Notch ligands at the surface of supramolecular biomaterials

    Author: de Jong, S., 23 May 2019

    Supervisor: Putti, M. (Supervisor 1) & Dankers, P. (Supervisor 2)

    Student thesis: Master

    Model-based assessment of calcifications in aortic stenosis and their role in valve opening

    Author: Janssens, K., 19 Dec 2019

    Supervisor: Rutten, M. (Supervisor 1) & Meiburg, R. (Supervisor 2)

    Student thesis: Master