Biomedical Materials and Chemistry

  • Institute for Complex Molecular Systems Department of Biomedical Engineering, P.O. Box 513

    5600 MB Eindhoven

    Netherlands

Organization profile

Introduction / mission

To provide material solutions for regenerative medicine through development of functional biomaterials based on supramolecular chemistry.

Highlighted phrase

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials.

Organisational profile

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials. The main goals are: 1. To develop methods to specifically modify biomaterials surfaces, and 2. To translate these biomaterials to applications in the field of regenerative medicine, with a focus on cardiovascular and renal applications.

The biomedical application of different supramolecular polymeric biomaterials held together via directed, non-covalent interactions is the central theme. In the cardiovascular field the aim is to develop vascular grafts and heart valves that in situ can be engineered by selective capturing of progenitor cells from the blood (in close collaboration with prof. Carlijn Bouten). Additionally, catheter-delivery methods of various drugs, cells and exosomes, encapsulated in hydrogels, to the heart after myocardial infarction are investigated. Furthermore, the Biomaterials research group also designs and develops biomaterials to intervene in processes related to kidney disease. In order to ameliorate hemodialysis bilayered supramolecular membranes on which kidney cells can be cultured outside the body are developed.

Fingerprint Dive into the research topics where Biomedical Materials and Chemistry is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Pyrimidinones Chemical Compounds
Hydrogels Engineering & Materials Science
Biocompatible Materials Chemical Compounds
Biomaterials Engineering & Materials Science
Hydrogel Chemical Compounds
Peptides Engineering & Materials Science
Scaffolds Chemical Compounds
Bone Chemical Compounds

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Research Output 2016 2019

  • 28 Article
  • 9 Phd Thesis 1 (Research TU/e / Graduation TU/e)
  • 1 Chapter
  • 1 Editorial
5 Downloads (Pure)
Open Access
File
Biocompatible Materials
Pyrimidinones
Proteins
Notch1 Receptor
Click Chemistry
9 Citations (Scopus)
18 Downloads (Pure)

Carbon nanotube reinforced supramolecular hydrogels for bioapplications

Mihajlovic, M., Mihajlovic, M., Dankers, P. Y. W., Masereeuw, R. & Sijbesma, R. P., 1 Jan 2019, In : Macromolecular Bioscience. 19, 12 p., 1800173.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Carbon Nanotubes
Hydrogels
Nanocomposites
Carbon nanotubes
Hydrogel

Prizes

NWO Vidi Award : Pieces of plastic with biological properties?

P.Y.W. Dankers (Recipient), 2016

Prize: NWOVidiScientific

Bearings (structural)
Tissue
Plastics
Polymers
Supramolecular chemistry
Biocompatible Materials
Medicine
Tissue
Medical problems

Supramolecular hydrogels as local controlled drug delivery carriers

P.Y.W. Dankers (Recipient), 2016

Prize: ERCProof of conceptScientific

Drug Carriers
Hydrogels
Hydrogel
Pyrimidinones
Drug Delivery Systems

Student theses

Introduction of Notch ligands at the surface of supramolecular biomaterials

Author: de Jong, S., 23 May 2019

Supervisor: Putti, M. (Supervisor 1) & Dankers, P. (Supervisor 2)

Student thesis: Master

Renal epithelial sheet response to curved surfaces

Author: Miltenburg, R., 30 Aug 2018

Supervisor: van Gaal, R. (Supervisor 1) & Dankers, P. (Supervisor 2)

Student thesis: Master