Biomedical Materials and Chemistry

  • Institute for Complex Molecular Systems Department of Biomedical Engineering, P.O. Box 513

    5600 MB Eindhoven

    Netherlands

Organization profile

Introduction / mission

To provide material solutions for regenerative medicine through development of functional biomaterials based on supramolecular chemistry.

Highlighted phrase

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials.

Organisational profile

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials. The main goals are: 1. To develop methods to specifically modify biomaterials surfaces, and 2. To translate these biomaterials to applications in the field of regenerative medicine, with a focus on cardiovascular and renal applications.

The biomedical application of different supramolecular polymeric biomaterials held together via directed, non-covalent interactions is the central theme. In the cardiovascular field the aim is to develop vascular grafts and heart valves that in situ can be engineered by selective capturing of progenitor cells from the blood (in close collaboration with prof. Carlijn Bouten). Additionally, catheter-delivery methods of various drugs, cells and exosomes, encapsulated in hydrogels, to the heart after myocardial infarction are investigated. Furthermore, the Biomaterials research group also designs and develops biomaterials to intervene in processes related to kidney disease. In order to ameliorate hemodialysis bilayered supramolecular membranes on which kidney cells can be cultured outside the body are developed.

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Research Output 2016 2019

  • 16 Article
  • 5 Phd Thesis 1 (Research TU/e / Graduation TU/e)
  • 1 Chapter

Carbon nanotube reinforced supramolecular hydrogels for bioapplications

Mihajlovic, M., Mihajlovic, M., Dankers, P. Y. W., Masereeuw, R. & Sijbesma, R. P., 1 Jan 2019, In : Macromolecular Bioscience. 19, 12 p., 1800173

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Carbon Nanotubes
Hydrogels
Nanocomposites
Carbon nanotubes
Hydrogel

Engineered cardiac microenvironments based on supramolecular biomaterials

Spaans, S., 13 Mar 2019, (Accepted/In press) Eindhoven: Technische Universiteit Eindhoven. 175 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Quantifying guest–host dynamics in supramolecular assemblies to analyze their robustness

Bastings, M. M. C., Hermans, T. M., Spiering, A. J. H., Kemps, E. W. L., Albertazzi, L., Kurisinkal, E. E. & Dankers, P. Y. W., 1 Jan 2019, In : Macromolecular Bioscience. 19, 1, 11 p., 1800296

Research output: Contribution to journalArticleAcademicpeer-review

Pyrimidinones
Fluorescence Recovery After Photobleaching
Photobleaching
Fluorescence Resonance Energy Transfer
Microfluidics

Prizes

NWO Vidi Award : Pieces of plastic with biological properties?

Patricia Dankers (Recipient), 2016

Recognition: NWOVidiScientific

Bearings (structural)
Tissue
Plastics
Polymers
Supramolecular chemistry
Biocompatible Materials
Medicine
Tissue
Medical problems

Supramolecular hydrogels as local controlled drug delivery carriers

Patricia Dankers (Recipient), 2016

Recognition: ERCProof of conceptScientific

Drug Carriers
Hydrogels
Hydrogel
Pyrimidinones
Drug Delivery Systems

Press / Media

Martijn Wieling elected vice chair of the The Young Academy

Patricia Dankers

29/01/18

1 item of media coverage

Press/Media: Expert Comment

Martijn Wieling elected Vice President of The Young Academy

Patricia Dankers

23/01/18

1 item of media coverage

Press/Media: Expert Comment

3D imaging MS shows surface functionalization

Olga Goor, Patricia Dankers & Moniek Schmitz

12/02/17

1 item of media coverage

Press/Media: Expert Comment