Content available in repository
Content available in repository
Organization profile
Introduction / mission
To provide material solutions for regenerative medicine through development of functional biomaterials based on supramolecular chemistry.
Highlighted phrase
Design and synthesis of bioinspired functional biomaterials.
Organisational profile
The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials. The main goals are: 1. To develop methods to specifically modify biomaterials surfaces, and 2. To translate these biomaterials to applications in the field of regenerative medicine, with a focus on cardiovascular and renal applications.
The biomedical application of different supramolecular polymeric biomaterials held together via directed, non-covalent interactions is the central theme. In the cardiovascular field the aim is to develop vascular grafts and heart valves that in situ can be engineered by selective capturing of progenitor cells from the blood (in close collaboration with prof. Carlijn Bouten). Additionally, catheter-delivery methods of various drugs, cells and exosomes, encapsulated in hydrogels, to the heart after myocardial infarction are investigated. Furthermore, the Biomaterials research group also designs and develops biomaterials to intervene in processes related to kidney disease. In order to ameliorate hemodialysis bilayered supramolecular membranes on which kidney cells can be cultured outside the body are developed.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Profiles
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Jasper G.M. Aarts
- Biomedical Engineering, Biomedical Materials and Chemistry - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Boris Arts, MSc
- Biomedical Engineering, Biomedical Materials and Chemistry - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Bram Bakker
- Biomedical Engineering, Biomedical Materials and Chemistry - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
Research output
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Animal studies for the evaluation of in situ tissue-engineered vascular grafts - a systematic review, evidence map, and meta-analysis
Koch, S. E., de Kort, B. J., Holshuijsen, N., Brouwer, H. F. M., van der Valk, D. C., Dankers, P. Y. W., van Luijk, J. A. K. R., Hooijmans, C. R., de Vries, R. B. M., Bouten, C. V. C. & Smits, A. I. P. M., 23 Feb 2022, In: npj Regenerative Medicine. 7, 1, 17 p., 17.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Citations (Scopus)45 Downloads (Pure) -
Antimicrobial Supramolecular Biomaterials: From Molecular Design to Screening
Schmitz, M. G. J., 15 Feb 2022, Eindhoven: Eindhoven University of Technology. 170 p.Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
Open AccessFile -
Bioinspired Silk Fibroin Mineralization for Advanced In Vitro Bone Remodeling Models
de Wildt, B. W. M., van der Meijden, R., Bartels, P. A. A., Sommerdijk, N. A. J. M., Akiva, A., Ito, K. & Hofmann, S., 10 Oct 2022, In: Advanced Functional Materials. 32, 41, 17 p., 2206992.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)29 Downloads (Pure)
Datasets
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Molecular Recognition: Comparative Study of a Tunable Host-Guest System by Using a Fluorescent Model System and Collision-Induced Dissociation Mass Spectrometry on Dendrimers
Nielsen, C. B. (Contributor), Christensen, J. B. (Contributor), Broeren, M. A. C. (Contributor), Meijer, E. W. (Contributor), van Dongen, J. L. J. (Contributor), Pittelkow, M. (Contributor) & Van Genderen, M. H. P. (Contributor), SupraBank, 2022
DOI: 10.34804/supra.20210928167
Dataset
Prizes
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NWO Vidi Award : Pieces of plastic with biological properties?
Dankers, P.Y.W. (Recipient), 2016
Prize: NWO › Vidi › Scientific
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Supramolecular Chemistry in Medicine:Towards Complex Molecular Biomaterials that are Indistinguishable from Nature
Dankers, P.Y.W. (Recipient), 2012
Prize: ERC › Starting › Scientific
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Supramolecular hydrogels as local controlled drug delivery carriers
Dankers, P.Y.W. (Recipient), 2016
Prize: ERC › Proof of concept › Scientific
Press / Media
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Eindhoven University of Technology: Chemists Find a Contrary Effect - How Diluting With Water Makes a Solution Firm
Patricia Y.W. Dankers & Ghislaine M.E. Vantomme
8/07/22
1 item of Media coverage
Press/Media: Expert Comment
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Chemists find a contrary effect: How diluting with water makes a solution firm
Patricia Y.W. Dankers & Ghislaine M.E. Vantomme
7/07/22
3 items of Media coverage
Press/Media: Expert Comment
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Prestigious NWO Gravitation Funding for New Eindhoven University of Technology Polymer Research Center
Jan C.M. van Hest, Patricia Y.W. Dankers & B. Fitzgerald
3/05/22
1 item of Media coverage
Press/Media: Expert Comment
Student theses
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Anisotropic swelling of a cylindrical hydrogel
Author: Braat, Q. J. S., Jul 2021Supervisor: Storm, C. (Supervisor 1) & Wu, D. J. (Supervisor 2)
Student thesis: Master
File -
Bioactive supramolecular 3D scaffolds mimicking the ECM through post-modification with glycopolymers
Author: Bahri, C., 27 Jan 2022Supervisor: Komil, M. (Supervisor 1), Bartels, P. A. A. (Supervisor 2) & Dankers, P. Y. W. (Supervisor 2)
Student thesis: Master
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Biomaterial-Driven Differentiation of Human Induced Pluripotent Stem Cells into Late Primitive Streak Cells: A Material-Based Approach Towards the Generation of Nephron Progenitor Cells and Kidney Organoids
Author: Broeders, A. E. J. A., 25 Aug 2022Supervisor: de Jong, S. M. J. (Supervisor 1) & Dankers, P. Y. W. (Supervisor 2)
Student thesis: Master