Organisation profile
Introduction / mission
Research at BiS is dedicated to understanding and applying basic cell biological principles at the biointerfaces especially for regenerative medicine. The research program is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental biology to streamline the wealth of biological knowledge to real clinical applications.
Highlighted phrase
Cell biology in regenerative medicine
Organisation profile
Cell biology, computational approaches, and material development are the three key fields of science that we focus our research on at BiS. To find out more, have a look at our website.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education
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Collaborations and top research areas from the last five years
Profiles
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Els Alsema
- Biomedical Engineering, Biointerface Science - Doctoral Candidate
Person: Prom. : doctoral candidate (PhD)
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Jan de Boer
- EAISI Health - Full Professor
- ICMS Core member - Full Professor
- Biomedical Engineering, Biointerface Science - Full Professor
Person: HGL : Professor
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Burcu Gumuscu
- Biomedical Engineering, Biointerface Science - University Researcher
- ICMS Affiliated member - University Researcher
- EAISI Health - University Researcher
- Biomedical Engineering, Departmental Office BMT - University Researcher
Person: OWP : University Teacher / Researcher
Projects
- 1 Finished
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CRT-OND-BayesBrain: The World's First Brain-on-Chip AI Computer
de Vries, A. (Project Manager), Sijbesma, R. P. (Project member), Adamiat, S. (Project member) & Kouw, W. (Project member)
1/10/21 → 31/03/26
Project: First tier
Research output
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Advanced microfluidic platforms and responsive surface technologies for modulating cellular behaviour
Savchak, O., 3 Feb 2026, Eindhoven: Eindhoven University of Technology. 214 p.Research output: Thesis › Phd Thesis 1 (Research TU/e / Graduation TU/e)
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Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
Kooi, R., Ul Islam, T., Stassen, O. M. J. A., Amsing, N., de Boer, J. & den Toonder, J. M. J. (Corresponding author), 1 Feb 2026, (E-pub ahead of print) In: Advanced Healthcare Materials. XX, e00001.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Controlling spatial organization of the cell - using surface micro-pillar patterns to manipulate Golgi morphology and function
Verbakel, J. & de Boer, J. (Corresponding author), 16 Mar 2026, In: Journal of Cell Science. 139, 5Research output: Contribution to journal › Article › Academic › peer-review
Datasets
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Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells
Vermeulen, S. A. A. (Creator), de Boer, J. (Contributor) & Hebels, D. (Contributor), DataverseNL, 18 Aug 2020
DOI: 10.34894/vvatm8, https://dataverse.nl/citation?persistentId=doi:10.34894/VVATM8
Dataset
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Micro-topographies induce epigenetic reprogramming and quiescence in human mesenchymal stem cells
Vermeulen, S. A. A. (Creator), de Boer, J. (Creator) & Hebels, D. G. A. J. (Contributor), DataverseNL, 7 Nov 2022
DOI: 10.34894/s2qx6c, https://dataverse.nl/citation?persistentId=doi:10.34894/S2QX6C
Dataset
Prizes
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INTERACTIVE POLYMER MATERIALS (IPM)
Gumuscu Sefunc, B. (Recipient), 2022
Prize: NWO › Gravitation › Scientific
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25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 (Event)
Gumuscu Sefunc, B. (Editorial board member), Manjua, A. C. (Editorial board member), Cabral, J. M. S. (Editorial board member), Castelo Ferreira, F. (Editorial board member), Gardeniers, J. G. E. (Editorial board member) & Portugal, C. A. M. (Editorial board member)
23 Oct 2022 → 27 Oct 2022Activity: Publication peer-review and editorial work types › Publication peer-review › Scientific
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Dutch Design Week 2022 (Event)
Gumuscu Sefunc, B. (Editorial board member), Savchak, O. (Editorial board member) & Li, L. (Editorial board member)
22 Oct 2022 → 30 Oct 2022Activity: Publication peer-review and editorial work types › Publication peer-review › Scientific
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human Organ and Disease Model Technologies (hDMT) (External organisation)
Gumuscu Sefunc, B. (Contributor)
Nov 2021Activity: Membership types › Membership of network › Scientific
Press/Media
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Reports from NOVA University Lisbon Add New Data to Findings in Health and Medicine (Design of Blood Vessel Models Using Magnetic-responsive Vascular Platforms)
28/09/23
1 item of Media coverage
Press/Media: Expert Comment
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Recent Findings from Xiamen University of Technology Highlight Research in Remote Sensing (A New Technique for Impervious Surface Mapping and Its Spatio-Temporal Changes from Landsat and Sentinel-2 Images)
Li, L.
12/06/23
1 item of Media coverage
Press/Media: Expert Comment
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Data on Sustainable Development Described by Researchers at Xiamen University of Technology (Mapping China's Changing Gross Domestic Product Distribution Using Remotely Sensed and Point-of-Interest Data with Geographical Random Forest Model)
Li, L.
8/06/23
1 item of Media coverage
Press/Media: Expert Comment
Research areas
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Droplet-Based Microfluidics
Tel, J. (Content manager), van Gorp, L. (Content manager), Broeders, A. (Content manager) & Looijenga, M. (Content manager)
Impact: Research Topic/Theme (at group level)
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Valve-Based Microfluidics
Tel, J. (Content manager), van Gorp, L. (Content manager), Broeders, A. (Content manager) & Looijenga, M. (Content manager)
Impact: Research Topic/Theme (at group level)
Student theses
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Analysis of Nuclear Dynamics and Morphology on Topographical Surfaces from Static Images
Derwig, S. (Author), de Boer, J. (Supervisor 1) & Bosnacki, D. (Supervisor 2), 29 Aug 2024Student thesis: Master
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A novel concept in ACL reconstruction surgery: an off-the-shelf decellularized and sterilized bone-ACL-bone allograft
Spierings, J. M. H. (Author), Foolen, J. (Supervisor 1) & Dede, A. (Supervisor 2), 22 Feb 2021Student thesis: Master
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Assessment of the Dynamic Interplay of Shear Stress and Surface Topographies on Hepatocytes in a Microfluidic Platform
Dekker, W. A. M. (Author), Gumuscu Sefunc, B. (Supervisor 1) & de Boer, J. (Supervisor 2), 2022Student thesis: Master